Iporuru + Rezafungin
Rezafungin brand name: Rezzayo.
We found no known interaction between Iporuru and Rezafungin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Iporuru and Rezafungin
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Rezafungin and Iporuru in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Iporuru at all — not against Rezafungin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Iporuru safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
See Every Supplement That Interacts With Rezafungin
This page covers Iporuru only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Rezafungin page lists 38 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Beer (major), Siberian Cocklebur (major), Wine (major), Ashwagandha (moderate) and Black Cohosh (moderate).
By severity: 3 major · 35 moderate.
From our pharmacist’s overview on the Rezafungin page
“Rezafungin (Rezzayo) is an intravenous antifungal used against serious, often life-threatening Candida infections, and every one of its 38 flagged supplements shares a single concern, added stress on the liver. Three interactions rate major, and two of those are alcohol in the form of beer and wine, alongside the herb Siberian cocklebu…”
Reviewed by 2 · Jul 18, 2026
Taking Iporuru as Part of a Dietary Supplement Product? Check It for Interactions
We hold 5 real supplement products containing Iporuru, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Iporuru. Even though Iporuru itself has no known interaction with Rezafungin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Iporuru and Rezafungin Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#666 of 1,452 supplements looked up here in the last 7 days
#1,098 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions. Iporuru is not yet covered by that licensed database, so its write-up cites publicly available medical sources directly (see the references below).
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Iporuru reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Iporuru and Rezafungin records this page draws on were last updated July 3, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Iporuru
What is Iporuru?
- Joint and muscle pain
- Arthritis and inflammation
- Rheumatism
- General aches and pains
- Digestive complaints
Iporuru is an Amazonian shrub traditionally used by Indigenous peoples for joint pain, arthritis, and inflammation. Scientific evidence in humans is very limited, so its true benefits and safety are not well established. Talk with your pharmacist or doctor before using it, especially if you take other medicines or have health conditions.
Alchornea castaneifolia · Euphorbiaceae · Bark and leaves · Tea, tincture, capsules, dried bark
An interaction check asks whether these two react with each other — it does not ask whether Iporuru is a good idea for someone in your situation. Here is what our Iporuru record says about it on its own.
Iporuru: dosing
There is no established or standardized dose for Iporuru. Traditional preparations vary, and supplement labels differ from one product to another.If you choose to use it, follow the directions on the product label and do not exceed the recommended amount.
From our Iporuru monograph — the full record covers uses, side effects and every documented interaction.
About Rezafungin Injection
What Is Rezafungin Injection Used For?
Brand name: Rezzayo
Rezzayo (rezafungin injection) is used to treat candidemia (a Candida yeast infection in the bloodstream) and invasive candidiasis (a serious Candida infection that has spread into the body's tissues or organs). It is approved for adults and for adolescents 12 years of age and older who have limited or no other treatment options.
Important note: Rezzayo has not been studied in Candida infections of the heart (endocarditis), bones (osteomyelitis), or the brain and spinal cord (meningitis), so it is not used for those conditions.
Most-Reported Side Effects for Rezafungin
From FAERS, the FDA’s public side-effect reporting system (0 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Iporuru
Browse every other medication we’ve checked against Iporuru — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Iporuru against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Ivermectin ›
- Abemaciclib ›
- Aspirin ›
- Metoprolol ›
- Acetaminophen ›
- Rosuvastatin ›
- Rivaroxaban ›
- Escitalopram ›
- Clopidogrel ›
- Atorvastatin ›
- Tadalafil ›
- Docusate ›
- Tirzepatide ›
- Ibuprofen ›
- Methamphetamine ›
- Hydroxyurea ›
- Warfarin Sodium ›
- Valacyclovir ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Lisdexamfetamine ›
- Propranolol ›
- Metformin ›
- Amitriptyline ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Methotrexate ›
- Amlodipine Besylate ›
- Bendamustine ›
- Bupropion ›
- Amphetamine ›
- Fluoxetine ›
- Doxycycline ›
- Acyclovir ›
- Azithromycin ›
- Lamotrigine ›
- Pregabalin ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Quetiapine ›
- Clonazepam ›
- Levothyroxine, Liothyronine ›
- Naproxen ›
- Omeprazole ›
- Letrozole ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Iporuru list.
Iporuru References
The 3 sources that drive our Iporuru monograph — publicly available pages from reputable medical and government organizations. Every link was verified to work before publishing. Iporuru is not covered by the licensed Natural Medicines interaction database, so its page cites these public sources directly.
- Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
- Herbs at a Glance — NIH NCCIH Source
- Herbal Supplements — MedlinePlus Source
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Taking Iporuru and Rezafungin Together: Common Questions
Is it safe to take Iporuru with Rezafungin?
Does Rezafungin interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Rezafungin and Iporuru?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.