Drug & supplement interaction

Lemon Verbena + Triazolam

Triazolam brand names: Halcion, Triazo, Apo-Triazo, Gen-Triazolam, Mylan-Triazolam, and others.

Moderate Interaction
The bottom line Moderate

Lemon Verbena has a moderate interaction with Triazolam. Theoretically, taking lemon verbena with benzodiazepines might increase the risk of sedation and respiratory depression.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Lemon Verbena and Triazolam

Here is the interaction we found between these two, with the evidence behind it.

Moderate

BENZODIAZEPINES

Why this applies to Triazolam

Triazolam falls under BENZODIAZEPINES — the group Lemon Verbena interacts with.

Theoretically, taking lemon verbena with benzodiazepines might increase the risk of sedation and respiratory depression.
Animal research shows that lemon verbena has additive sedative effects in mice that also received diazepam.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Triazolam (Halcion) is a benzodiazepine sleeping pill, so it already works by calming brain activity to help you drift off. The concern here is simple: lemon verbena may add a little extra sedation on top of what your sleeping pill already does. In theory, that could mean feeling groggier, more drowsy the next morning, or having trouble with balance and clear thinking.

I want to be honest about the evidence though. This is based mostly on a mouse study, not on people, so it's a theoretical caution rather than a proven problem. A cup of lemon verbena tea is unlikely to cause trouble, but concentrated supplement doses are harder to predict. If you're taking triazolam regularly, just run your lemon verbena use by your pharmacist or doctor first.

References
  1. Afrasiabian F, Mirabzadeh Ardakani M, Rahmani K, et al. Aloysia citriodora Palau (lemon verbena) for insomnia patients: A randomized, double-blind, placebo-controlled clinical trial of efficacy and safety. Phytother Res. 2019;33(2):350-359.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Lemon Verbena Also Interacts With Other Medications

Lemon Verbena has 21 moderate known drug interactions in our database — the Triazolam one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Lemon Verbena

Covers the 2,830 medications we’ve checked against Lemon Verbena. Pick one to open its full report.

From our Q&A

Questions About Lemon Verbena or Triazolam

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Lemon Verbena or Triazolam, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Triazolam

This page covers Lemon Verbena only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Triazolam page lists 197 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: 1,4-butanediol (major), Activated Charcoal (major), Beer (major), Gamma-hydroxybutyrate (ghb) (major) and Grapefruit (major).

By severity: 9 major · 150 moderate · 38 minor.

From our pharmacist’s overview on the Triazolam page

“Triazolam (Halcion) is a potent, fast-acting sleep medication, and I'd approach its supplement list with genuine care rather than a quick skim. Nine of the 197 flagged ingredients carry a major rating, and they cluster around two problems.”

Reviewed by 2 · Jul 18, 2026

Open the Triazolam interaction page

One more smart check

Taking Lemon Verbena as Part of a Dietary Supplement Product? Check It for Interactions

We hold 32 real supplement products containing Lemon Verbena, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Lemon Verbena. Your product may carry other ingredients that interact with Triazolam too, on top of Lemon Verbena — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Lemon Verbena and Triazolam Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Lemon Verbena
Top half

#646 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Triazolam
Top half

#949 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Lemon Verbena

What is Lemon Verbena?

Lemon Verbena
  • Digestive upset
  • Anxiety and trouble sleeping
  • Joint pain and inflammation
  • Exercise recovery and oxidative stress
  • Weight management
  • Flavoring and aromatherapy

Lemon verbena is a fragrant South American herb most often enjoyed as a tea or flavoring, and it contains polyphenols like verbascoside that have antioxidant activity in lab studies. Some small studies hint at benefits for inflammation, exercise recovery, and appetite, but the human evidence is limited and far from proven. It is generally well tolerated as a food and tea, but talk with your pharmacist or doctor before using concentrated supplements, and avoid it during pregnancy and breastfeeding.

Read the full Lemon Verbena monograph & all interactions
Medication

About Triazolam

What Is Triazolam Used For?

Brand names: Halcion, Triazo, Apo-Triazo, Gen-Triazolam, Mylan-Triazolam, Novo-Triolam, Nu-Triazo

Triazolam tablets are used for the short-term treatment of insomnia in adults — generally for 7 to 10 days. It is not intended for long-term use. If sleep problems last beyond 2 to 3 weeks, a full medical evaluation is needed to look for an underlying cause.

Halcion (brand-name triazolam) is specifically indicated for short-term insomnia in adults, with prescriptions written for no more than a 1-month supply. Generic triazolam tablets carry the same indication and the same duration limits.

See full Triazolam drug information
Keep checking

Other Drugs & Lemon Verbena

Browse every other medication we’ve checked against Lemon Verbena — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
21Moderate
0Minor
2,808No known interaction
Moderate

21 interactions

No interaction 2,808 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Lemon Verbena and Triazolam Together: Common Questions

Can you take Lemon Verbena with Triazolam?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Lemon Verbena and Triazolam interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Triazolam and Lemon Verbena?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.