Drug & supplement interaction

Mountain Ash + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide

Aluminum Hydroxide, Aspirin, Magnesium Hydroxide brand name: Ascriptin.

Moderate Interaction
Medically reviewed by · Updated September 2026
The bottom line Moderate

Mountain Ash has a moderate interaction with Aluminum Hydroxide, Aspirin, Magnesium Hydroxide. Taking large amounts of fresh mountain ash berries may cause kidney damage due to its parasorbic acid constituent.

Read the full interaction report
SeverityModerate
LikelihoodPossible
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Mountain Ash and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide

Here is the interaction we found between these two, with the evidence behind it.

Moderate

NEPHROTOXIC DRUGS

Why this applies to Aluminum Hydroxide, Aspirin, Magnesium Hydroxide

Aluminum Hydroxide, Aspirin, Magnesium Hydroxide falls under NEPHROTOXIC DRUGS — the group Mountain Ash interacts with.

Taking large amounts of fresh mountain ash berries may cause kidney damage due to its parasorbic acid constituent. Theoretically, taking mountain ash berries with nephrotoxic drugs might increase the risk for kidney damage. Until more is known, advise patients to avoid taking mountain ash berries if they are taking other potentially nephrotoxic drugs.
Some potentially nephrotoxic drugs include cyclosporine (Neoral, Sandimmune); aminoglycosides including amikacin (Amikin), gentamicin (Garamycin, Gentak, others), and tobramycin (Nebcin, others); nonsteroidal anti-inflammatory drugs (NSAIDs) including ibuprofen (Advil, Motrin, Nuprin, others), indomethacin (Indocin), naproxen (Aleve, Anaprox, Naprelan, Naprosyn), piroxicam (Feldene); and numerous others.
Severity Moderate Likelihood Possible Evidence D

Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the gist for this combo product (which pairs aspirin with two antacids, aluminum and magnesium hydroxide). The worry isn't about how your body breaks the aspirin down. It's about your kidneys. Aspirin, like other anti-inflammatory pain relievers, can be a little hard on the kidneys, especially with regular use or in folks who are older or dehydrated.

Mountain ash berries contain a compound called parasorbic acid, and in large amounts of fresh berries it could theoretically stress the kidneys too. Stacking those two together might add up. I'll be honest, this is based on pharmacology theory, not real human studies, so don't panic. A little cooked rowan jam is unlikely to matter, but concentrated supplement doses are a different story. Check with your pharmacist or doctor before combining them.

Contact Dr. Brian directly if you have additional questions on this interaction
References
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Mountain Ash Also Interacts With Other Medications

Mountain Ash has 354 moderate known drug interactions in our database — the Aluminum Hydroxide, Aspirin, Magnesium Hydroxide one above is one of them. If you take anything else, check it against the full list below.

Moderate 354 No known interaction 2,476 (incl. Aluminum Hydroxide, Aspirin, Magnesium Hydroxide)
Taking anything else?

Check Another of Your Medications Against Mountain Ash

Covers the 2,830 medications we’ve checked against Mountain Ash. Pick one to open its full report.

From our Q&A

Questions About Mountain Ash or Aluminum Hydroxide, Aspirin, Magnesium Hydroxide

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Mountain Ash or Aluminum Hydroxide, Aspirin, Magnesium Hydroxide, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Aluminum Hydroxide, Aspirin, Magnesium Hydroxide

This page covers Mountain Ash only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Aluminum Hydroxide, Aspirin, Magnesium Hydroxide page lists 255 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Danshen (major) and Piracetam (major).

By severity: 7 major · 211 moderate · 37 minor.

From our pharmacist’s overview on the Aluminum Hydroxide, Aspirin, Magnesium Hydroxide page

“Ascriptin combines aspirin with two antacids, aluminum hydroxide and magnesium hydroxide, and the aspirin part already thins the blood on its own. That is why more than 200 of the 255 ingredients listed here can raise bleeding risk, and why this page deserves a careful read rather than a quick skim.”

Reviewed by 2 · Jul 18, 2026

Open the Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interaction page

One more smart check

Taking Mountain Ash as Part of a Dietary Supplement Product? Check It for Interactions

We hold 1 real supplement products containing Mountain Ash, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Mountain Ash. Your product may carry other ingredients that interact with Aluminum Hydroxide, Aspirin, Magnesium Hydroxide too, on top of Mountain Ash — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Mountain Ash and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Mountain Ash
Steady interest

#839 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Aluminum Hydroxide, Aspirin, Magnesium Hydroxide
Top 1%

#28 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Mountain Ash

What is Mountain Ash?

Mountain Ash
  • Sore throat and hoarseness
  • Digestive upset and constipation
  • Cough and chest congestion
  • Mild urinary complaints
  • Source of vitamin C in folk medicine

Mountain ash (rowan) is a northern-hemisphere tree whose bright red berries are traditionally cooked into jams, syrups, and teas. There is very little reliable human research to support any medical use, and raw berries contain compounds that can cause stomach upset, so cooking is important. If you want to try it, talk with your pharmacist or doctor first.

Read the full Mountain Ash monograph & all interactions
Medication

About Aspirin

What Is Aspirin Used For?

Brand name: Ascriptin

Aspirin is used to temporarily relieve minor aches and pains from headaches, backaches, muscle aches, toothaches, menstrual cramps, the common cold, and minor arthritis pain. It also temporarily reduces fever.

Some coated aspirin tablet products note that, under a doctor's supervision, aspirin can help prevent another heart attack or stroke in adults who have already had one. Because of their delayed-release design, those coated products will not give fast relief for headaches or other symptoms needing quick relief.

See full Aspirin drug information
Keep checking

Other Drugs & Mountain Ash

Browse every other medication we’ve checked against Mountain Ash — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
354Moderate
0Minor
2,475No known interaction
354 Moderate 2,475 No interaction
Moderate

354 interactions

Showing 60 of 354 moderate interactions — see all 354 on the Mountain Ash page.

No interaction 2,475 drugs checked — show the list

We also checked Mountain Ash against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,475 medications checked with no known interaction — see the full Mountain Ash list.

See the full Mountain Ash interactions page
See every supplement checked against Aluminum Hydroxide, Aspirin, Magnesium Hydroxide, ranked by severity
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Mountain Ash monograph › Uses, safety, and every drug interaction in one place Aluminum Hydroxide, Aspirin, Magnesium Hydroxide supplement interactions › Every supplement checked against Aluminum Hydroxide, Aspirin, Magnesium Hydroxide, ranked by severity Aspirin drug information › The full plain-English guide to this medication Supplement interaction checker › Check any supplement or product against your medications Browse medications A–Z › Every drug we've checked against herbs & supplements Ask a pharmacist › Free, personal answer from our licensed team
Pharmacist Counseling Corner

Taking Mountain Ash and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide Together: Common Questions

Can you take Mountain Ash with Aluminum Hydroxide, Aspirin, Magnesium Hydroxide?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Mountain Ash and Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Aluminum Hydroxide, Aspirin, Magnesium Hydroxide and Mountain Ash?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.