Osha + Bazedoxifene Acetate, Conjugated Estrogens
Bazedoxifene Acetate, Conjugated Estrogens brand name: Duavee.
We found no known interaction between Osha and Bazedoxifene Acetate, Conjugated Estrogens in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.
Osha and Bazedoxifene Acetate, Conjugated Estrogens
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Bazedoxifene Acetate, Conjugated Estrogens and Osha in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Osha at all — not against Bazedoxifene Acetate, Conjugated Estrogens, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Osha safety at a glance
Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Osha in Pregnancy & Breastfeeding
When used orally. Osha has been used to stimulate menstruation and is reported to have abortifacient activity; contraindicated.
DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center
See Every Supplement That Interacts With Bazedoxifene Acetate, Conjugated Estrogens
This page covers Osha only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Bazedoxifene Acetate, Conjugated Estrogens page lists 187 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Grapefruit (major), St. John's Wort (major), Acacia Rigidula (moderate) and Adrafinil (moderate).
By severity: 3 major · 152 moderate · 32 minor.
From our pharmacist’s overview on the Bazedoxifene Acetate, Conjugated Estrogens page
“If you take Duavee (bazedoxifene with conjugated estrogens) for hot flashes or bone protection after menopause, give this list genuine care, because three of its 187 supplement interactions rate major. Grapefruit and St.”
Reviewed by 2 · Jul 18, 2026
Open the Bazedoxifene Acetate, Conjugated Estrogens interaction page
Taking Osha as Part of a Dietary Supplement Product? Check It for Interactions
We hold 336 real supplement products containing Osha, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Osha. Even though Osha itself has no known interaction with Bazedoxifene Acetate, Conjugated Estrogens, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Osha and Bazedoxifene Acetate, Conjugated Estrogens Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#464 of 1,452 supplements looked up here in the last 7 days
#286 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Osha reference on this page ↓
- Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Osha and Bazedoxifene Acetate, Conjugated Estrogens records this page draws on were last updated July 11, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Osha
What is Osha?
- Cough and sore throat
- Respiratory infections and colds
- Immune support
- Digestive upset
- Bronchitis and congestion
Osha is a root from a wild mountain plant native to the western United States and Mexico, traditionally used by Native American and Hispanic communities for coughs, colds, and sore throats. Solid human research is lacking, so its benefits remain unproven, and it should be avoided during pregnancy and breastfeeding. Talk to your pharmacist or doctor before trying it.
Ligusticum porteri · Apiaceae · Root · Tea, tincture, capsules, lozenges, chewed raw root
An interaction check asks whether these two react with each other — it does not ask whether Osha is a good idea for someone in your situation. Here is what our Osha record says about it on its own.
Osha: dosing
There is no established standard dose for osha. The right amount depends on the form (tea, tincture, capsule, or lozenge) and the product's strength.If you choose to use osha, follow the directions on the product label and do not exceed them.
From our Osha monograph — the full record covers uses, side effects and every documented interaction.
About Estrogen and Bazedoxifene
What Is Estrogen and Bazedoxifene Used For?
Brand name: Duavee
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Estrogen and bazedoxifene tablets are used to treat hot flashes (sudden feelings of warmth, especially in the face, neck, and chest) in women who are experiencing menopause (stage of life when menstrual periods become less frequent and stop and women may experience other symptoms and body changes). Estrogen and bazedoxifene tablets are also used to prevent osteoporosis (condition in which the bones become thin and weak and break easily) in women who have undergone menopause. Estrogen is in a class of medications called hormones and bazedoxifene is in a class of medications called estrogen agonist–antagonists. Estrogen works by replacing estrogen that is normally produced by the body. Bazedoxifene is used to block the action of estrogen on the lining of the uterus, decreasing the risk of overgrowth that may lead to cancer.
Other Drugs & Osha
Browse every other medication we’ve checked against Osha — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Osha against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Ivermectin ›
- Testosterone ›
- Losartan Potassium ›
- Abemaciclib ›
- Aspirin ›
- Acetaminophen ›
- Metoprolol ›
- Rosuvastatin ›
- Escitalopram ›
- Rivaroxaban ›
- Clopidogrel ›
- Atorvastatin ›
- Docusate ›
- Tirzepatide ›
- Methamphetamine ›
- Tadalafil ›
- Ibuprofen ›
- Valacyclovir ›
- Warfarin Sodium ›
- Hydroxyurea ›
- Sumatriptan ›
- Semaglutide ›
- Prednisone ›
- Propranolol ›
- Amitriptyline ›
- Lisdexamfetamine ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Isotretinoin ›
- Methotrexate ›
- Amlodipine Besylate ›
- Bendamustine ›
- Amphetamine ›
- Bupropion ›
- Doxycycline ›
- Fluoxetine ›
- Acyclovir ›
- Azithromycin ›
- Pregabalin ›
- Lamotrigine ›
- Dextroamphetamine ›
- Gabapentin ›
- Acetaminophen, Codeine ›
- Levothyroxine, Liothyronine ›
- Quetiapine ›
- Clonazepam ›
- Naproxen ›
- Omeprazole ›
- Duloxetine ›
- Letrozole ›
- Methylene Blue ›
- Buspirone ›
- Citalopram ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Osha list.
Osha References
The 2 references that drive our Osha monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
Bazedoxifene Acetate, Conjugated Estrogens Is Linked to Lower Levels of 5 Nutrients
Natural Medicines records Bazedoxifene Acetate, Conjugated Estrogens as a medicine that can lower these. This is not an interaction with Osha — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Bazedoxifene Acetate, Conjugated Estrogens nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Osha and Bazedoxifene Acetate, Conjugated Estrogens Together: Common Questions
Is it safe to take Osha with Bazedoxifene Acetate, Conjugated Estrogens?
Does Bazedoxifene Acetate, Conjugated Estrogens interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Still Have a Question About Bazedoxifene Acetate, Conjugated Estrogens and Osha?
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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.