Drug & supplement interaction

Parsnip + Digoxin

Digoxin brand names: Lanoxicaps, Lanoxin, Digitek.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Oct 4, 2026
The bottom line No known interaction

We found no known interaction between Parsnip and Digoxin in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Parsnip and Digoxin

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Digoxin and Parsnip in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Parsnip at all — not against Digoxin, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Parsnip safety at a glance

Parsnip overall Use caution Safe as a food, but its leaves, sap, and seeds contain compounds that can cause skin reactions with sun exposure.
Pregnancy Use caution Fine as a normal food, but avoid concentrated supplement or medicinal amounts due to lack of safety data.
Breastfeeding Use caution Safe as a food, but the safety of medicinal or concentrated amounts is not known.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Digoxin and Parsnip? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Parsnip and Digoxin May Share a Side Effect

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • A skin rash Additional detail

    Parsnip

    “Topically, contact dermatitis and phototoxic reactions (including skin blisters) are possible following exposure to parsnip sap or fresh parsnip root and exposure to sunlight. Allergic contact dermatitis can occur but is rare.”

    Parsnip · Natural Medicines adverse-effect record, reported in dermatitis.

    4 sources cited
    1. 10071. Ivie GW, Holt DL, Ivey MC. Natural toxicants in human foods: psoralens in raw and cooked parsnip root. Science 1981;213:909-10.. PubMed
    2. 68289. Lutchman, L., Inyang, V., and Hodgkinson, D. Phytophotodermatitis associated with parsnip picking. J.Accid.Emerg.Med. 1999;16(6):453-454. PubMed
    3. 68291. Aberer, W. Occupational dermatitis from organically grown parsnip (Pastinaca sativa L.). Contact Dermatitis 1992;26(1):62.
    4. 68295. Bang, Pedersen N. and Pla Arles, U. B. Phototoxic reaction to parsnip and UV-A sunbed. Contact Dermatitis 1998;39(2):97. PubMed

    “Topically, contact dermatitis and phototoxic reactions, including skin blisters and later hyperpigmentation, have occurred following exposure to parsnip sap or fresh parsnip root and exposure to sunlight or UV-A light from a sunbed. Light-skinned people may be particularly susceptible to these reactions.

    A case report describes a 51-year-old male who developed rashes on his hands after preparing parsnip.”

    Parsnip · Natural Medicines adverse-effect record, reported in dermatitis.

    6 sources cited
    1. 10071. Ivie GW, Holt DL, Ivey MC. Natural toxicants in human foods: psoralens in raw and cooked parsnip root. Science 1981;213:909-10.. PubMed
    2. 68289. Lutchman, L., Inyang, V., and Hodgkinson, D. Phytophotodermatitis associated with parsnip picking. J.Accid.Emerg.Med. 1999;16(6):453-454. PubMed
    3. 68291. Aberer, W. Occupational dermatitis from organically grown parsnip (Pastinaca sativa L.). Contact Dermatitis 1992;26(1):62.
    4. 68295. Bang, Pedersen N. and Pla Arles, U. B. Phototoxic reaction to parsnip and UV-A sunbed. Contact Dermatitis 1998;39(2):97. PubMed
    5. 111192. White JML, Pink AE. English Sunday lunch dermatitis: Allergic contact dermatitis to parsnip, carrot, fennel (and ivy). Contact Dermatitis. 2020 Oct;83(4):317-8. PubMed
    6. 111193. Lafon A, Boulard C. Perioral phytophotodermatitis induced by parsnip mash. Contact Dermatitis. 2020 Oct;83(4):318-9. PubMed

    Digoxin

    Listed in the ADVERSE REACTIONS section of the FDA label for Digoxin. Read the label on DailyMed ›

Reported for Parsnip but not commonly for Digoxin: swelling.

Effects for Digoxin come from the ADVERSE REACTIONS section of its FDA label; effects for Parsnip come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

From our Q&A

Questions About Parsnip or Digoxin

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Parsnip or Digoxin, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Digoxin

This page covers Parsnip only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Digoxin page lists 113 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Aloe (major), Blue Flag (major), Danshen (major) and European Buckthorn (major).

By severity: 18 major · 79 moderate · 16 minor.

From our pharmacist’s overview on the Digoxin page

“Digoxin is a heart medicine with a narrow therapeutic index, meaning the gap between a helpful blood level and a harmful one is small, and few drugs give me more pause when supplements enter the picture. The most serious entries here are herbs that themselves contain digoxin-like cardiac glycosides, foxglove and lily-of-the-valley amon…”

Reviewed by 2 · Jul 18, 2026

Open the Digoxin interaction page

One more smart check

Taking Parsnip as Part of a Dietary Supplement Product? Check It for Interactions

We hold 38 real supplement products containing Parsnip, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Parsnip. Even though Parsnip itself has no known interaction with Digoxin, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Parsnip and Digoxin Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Parsnip
Steady interest

#1,168 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Digoxin
Top 25%

#379 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Parsnip reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified October 4, 2026. The Parsnip and Digoxin records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Parsnip

What is Parsnip?

  • Digestive support
  • Mild diuretic ('water pill') effect
  • Nutritional/dietary fiber source
  • Traditional kidney and urinary support
  • General wellness

Parsnip is mainly a nutritious root vegetable that is safe and healthy as part of a normal diet. Its use as a concentrated supplement or herbal remedy is not well studied, and certain parts of the plant can make skin very sensitive to sunlight. Talk to your pharmacist or doctor before using parsnip in any medicinal or high-dose form.

Pastinaca sativa · Apiaceae · Root, leaves, seeds, and essential oil · Whole root (food), cooked vegetable, juice, dried seeds, and rarely supplements or essential oil

An interaction check asks whether these two react with each other — it does not ask whether Parsnip is a good idea for someone in your situation. Here is what our Parsnip record says about it on its own.

Parsnip: dosing

There is no established medicinal dose for parsnip. As a food, it is simply eaten as a vegetable in normal serving amounts.If you choose to use a parsnip supplement, juice, or extract, there is no standardized dose backed by research.

From our Parsnip monograph — the full record covers uses, side effects and every documented interaction.

Read the full Parsnip monograph & all interactions
Medication

About Digoxin

What Is Digoxin Used For?

Brand names: Lanoxicaps, Lanoxin, Digitek

Digoxin treats mild to moderate heart failure in adults. It improves heart failure symptoms and exercise capacity, and it reduces heart failure-related hospitalizations and emergency care. It does not change survival.

It also helps control the resting heart rate in adults with chronic atrial fibrillation (an irregular heartbeat). In children with heart failure, the tablet, oral solution and most injection products are used to increase the heart’s pumping strength (myocardial contractility). Some older injection labels list only the adult uses. Digoxin Oral Solution should not be used for multifocal atrial tachycardia.

See full Digoxin drug information
Keep checking

Other Drugs & Parsnip

Browse every other medication we’ve checked against Parsnip — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Parsnip against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Parsnip list.

See the full Parsnip interactions page
See every supplement checked against Digoxin, ranked by severity
Evidence & sources

Parsnip References

The 6 references that drive our Parsnip monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Ivie GW, Holt DL, Ivey MC. Natural toxicants in human foods: psoralens in raw and cooked parsnip root. Science 1981;213:909-10.. PubMed
  2. Lutchman, L., Inyang, V., and Hodgkinson, D. Phytophotodermatitis associated with parsnip picking. J.Accid.Emerg.Med. 1999;16(6):453-454. PubMed
  3. Aberer, W. Occupational dermatitis from organically grown parsnip (Pastinaca sativa L.). Contact Dermatitis 1992;26(1):62.
  4. Bang, Pedersen N. and Pla Arles, U. B. Phototoxic reaction to parsnip and UV-A sunbed. Contact Dermatitis 1998;39(2):97. PubMed
  5. White JML, Pink AE. English Sunday lunch dermatitis: Allergic contact dermatitis to parsnip, carrot, fennel (and ivy). Contact Dermatitis. 2020 Oct;83(4):317-8. PubMed
  6. Lafon A, Boulard C. Perioral phytophotodermatitis induced by parsnip mash. Contact Dermatitis. 2020 Oct;83(4):318-9. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Parsnip and Digoxin Together: Common Questions

Is it safe to take Parsnip with Digoxin?
We do not list a known interaction between Parsnip and Digoxin. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Parsnip and Digoxin have any of the same side effects?
Yes — our sources link each of them separately to one of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Digoxin interact with any supplements?
Yes. Digoxin has documented interactions with 113 supplements in our database — Parsnip is not one of them. The Digoxin interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Parsnip monograph Uses, safety profile, and every drug interaction in one place Digoxin drug information The full plain-English guide to this medication Digoxin supplement interactions Every supplement checked against Digoxin, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 6 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Digoxin and Parsnip?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.