Drug & supplement interaction

Phlorizin + Chloroprocaine Hydrochloride

Chloroprocaine Hydrochloride brand name: Clorotekal.

No Known Interaction
Medically reviewed by · Updated June 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Phlorizin and Chloroprocaine Hydrochloride in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Phlorizin and Chloroprocaine Hydrochloride

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Chloroprocaine Hydrochloride and Phlorizin in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Phlorizin safety at a glance

Phlorizin overall Not established Human safety data for phlorizin supplements are very limited.
Pregnancy Avoid There is no reliable safety data, so it is best avoided in pregnancy.
Breastfeeding Avoid No safety information exists for nursing, so avoid use.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Chloroprocaine Hydrochloride and Phlorizin? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Chloroprocaine Hydrochloride

Interactions in our licensed database are recorded against drug classes, not just single drug names. Chloroprocaine Hydrochloride is filed under a single classification — anesthesia. Phlorizin has documented interactions with 1 drug class — the most serious being antidiabetes drugs (moderate) — and none of Chloroprocaine Hydrochloride’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Phlorizin Does Interact With Other Medications

Phlorizin has 86 moderate known drug interactions in our database — Chloroprocaine Hydrochloride isn’t one of them. If you take anything else, check it against the full list below.

Moderate 86 No known interaction 2,744 (incl. Chloroprocaine Hydrochloride)
Taking anything else?

Check Another of Your Medications Against Phlorizin

Covers the 2,830 medications we’ve checked against Phlorizin. Pick one to open its full report.

What to actually watch for

What Chloroprocaine Hydrochloride’s Own FDA Label Lists

This is not an interaction — none of it involves Phlorizin. These are the most notable effects listed in the ADVERSE REACTIONS section of Chloroprocaine Hydrochloride’s own FDA label, for the medication by itself. Knowing the drug’s own list makes it easier to work out the likely cause if something new turns up while you take both. 5 of them are worth acting on rather than waiting out — marked below.

  • A slow heartbeat Worth acting on
  • Fainting Worth acting on
  • Seizures Worth acting on
  • Low mood Worth acting on
  • Hives Worth acting on
  • Ringing in the ears
  • Blurred vision
  • Sweating
  • Back pain
  • A fast or pounding heartbeat

Showing the 10 most notable of 19 label-listed effects — ranked by how unusual each one is across medicines generally, with serious effects weighted up.

From the ADVERSE REACTIONS section of the FDA label for Chloroprocaine Hydrochloride. Read the label on DailyMed › Where a percentage is shown, it is the share of 138 voluntary FDA FAERS reports for Chloroprocaine Hydrochloride that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Phlorizin’s licensed record lists no adverse effects our clinical vocabulary could match, so there is no Phlorizin side to compare — that is a limit of the record, not a statement that Phlorizin has no side effects.

Everything else you take

See Every Supplement That Interacts With Chloroprocaine Hydrochloride

This page covers Phlorizin only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Chloroprocaine Hydrochloride page lists 5 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Fever Bark (major), Cannabis (moderate), Cowhage (moderate), Datura Wrightii (moderate) and Delta-9-tetrahydrocannabinol (thc) (moderate).

Open the Chloroprocaine Hydrochloride interaction page

One more smart check

Taking Phlorizin as Part of a Dietary Supplement Product? Check It for Interactions

We hold 6 real supplement products containing Phlorizin, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Phlorizin. Even though Phlorizin itself has no known interaction with Chloroprocaine Hydrochloride, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Phlorizin and Chloroprocaine Hydrochloride Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Phlorizin
Top half

#399 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Chloroprocaine Hydrochloride
Steady interest

#2,283 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Phlorizin reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Phlorizin and Chloroprocaine Hydrochloride records this page draws on were last updated June 22, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Phlorizin

What is Phlorizin?

  • Blood sugar support
  • Diabetes research
  • Antioxidant
  • Weight management interest

Phlorizin is a natural plant compound (a dihydrochalcone) found in apple tree bark and other plants that has been studied mostly in the laboratory for its effects on blood sugar handling. There is no good human evidence that taking it as a supplement is safe or effective, and it is poorly absorbed when swallowed. Talk with your pharmacist or doctor before using any product containing it.

Root bark, bark, and leaves of apple trees and related Rosaceae plants · Purified compound (research chemical), capsules, powders

An interaction check asks whether these two react with each other — it does not ask whether Phlorizin is a good idea for someone in your situation. Here is what our Phlorizin record says about it on its own.

Phlorizin: dosing

There is no established or standardized dose of phlorizin for supplement use in humans. It has mainly been used in research settings at carefully controlled amounts, not as a routine oral supplement.If you choose to use a product that contains phlorizin or apple bark extract, follow the directions on the product label and do not exceed the recommended amount.

From our Phlorizin monograph — the full record covers uses, side effects and every documented interaction.

Read the full Phlorizin monograph & all interactions
Medication

About Chloroprocaine Hydrochloride

Most-Reported Side Effects for Chloroprocaine Hydrochloride

From FAERS, the FDA’s public side-effect reporting system (138 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Underdose 54 reports
Eye pain 19 reports
Eye irritation 18 reports
Ocular hyperaemia 8 reports
Lacrimation increased 7 reports
Keep checking

Other Drugs & Phlorizin

Browse every other medication we’ve checked against Phlorizin — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
86Moderate
0Minor
2,743No known interaction
86 Moderate 2,743 No interaction
Moderate

86 interactions

Showing 60 of 86 moderate interactions — see all 86 on the Phlorizin page.

No interaction 2,743 drugs checked — show the list

We also checked Phlorizin against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,743 medications checked with no known interaction — see the full Phlorizin list.

See the full Phlorizin interactions page
See every supplement checked against Chloroprocaine Hydrochloride, ranked by severity
Evidence & sources

Phlorizin References

The 1 references that drive our Phlorizin monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Chao EC, Henry RR. SGLT2 inhibition--a novel strategy for diabetes treatment. Nat Rev Drug Discov. 2010;9(7):551-9. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Phlorizin and Chloroprocaine Hydrochloride Together: Common Questions

Is it safe to take Phlorizin with Chloroprocaine Hydrochloride?
We do not list a known interaction between Phlorizin and Chloroprocaine Hydrochloride. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Phlorizin and Chloroprocaine Hydrochloride combination checked?
Interactions in our licensed database are recorded against drug classes. Chloroprocaine Hydrochloride is filed under 1 classification, and Phlorizin has documented interactions with 1 drug class — none of Chloroprocaine Hydrochloride's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Phlorizin interact with any other medications?
Yes. Phlorizin has 86 documented drug interactions in our database — Chloroprocaine Hydrochloride is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Chloroprocaine Hydrochloride interact with any supplements?
Yes. Chloroprocaine Hydrochloride has documented interactions with 5 supplements in our database — Phlorizin is not one of them. The Chloroprocaine Hydrochloride interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Phlorizin monograph Uses, safety profile, and every drug interaction in one place Chloroprocaine Hydrochloride supplement interactions Every supplement checked against Chloroprocaine Hydrochloride, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 1 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Chloroprocaine Hydrochloride and Phlorizin?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.