Quince + Rifapentine
Rifapentine brand name: Priftin.
We found no known interaction between Quince and Rifapentine in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the label for Rifapentine states a food rule worth keeping to.
Quince and Rifapentine
We checked these two against our interaction database. Here is what we found.
No Known Interaction Found
We did not find a documented interaction between Rifapentine and Quince in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.
Worth understanding: our licensed dataset holds no drug-interaction record for Quince at all — not against Rifapentine, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.
If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.
Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.
Quince safety at a glance
Safety guidance is general; always confirm with your pharmacist or doctor for your situation.
Some Rifapentine Products Have a Food Rule — Quince Should Not Break It
At least one FDA label for a product containing Rifapentine says to take it with food. If you take Quince on an empty stomach out of habit, keep them separate — and take Rifapentine with a meal where the label says to.
This may not be true of your version. Food instructions belong to the product, not the ingredient: two Rifapentine products can carry different directions, and extended-release forms often differ from immediate-release ones. The label we read is quoted below — check the directions on your own box or bottle, or ask your pharmacist, for how to take the exact product you were given.
( 2.2 ) Take with food.
From the Dosage and Administration section of the FDA label we read for Rifapentine — where that label names a specific product, the instruction is that product's. Read the label on DailyMed ›
A food rule is not an interaction — it is about how much of the medicine you absorb. The directions that came with your own product, and your pharmacist, outrank anything on this page.
See Every Supplement That Interacts With Rifapentine
This page covers Quince only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Rifapentine page lists 64 supplements it has a documented interaction with, worst first, each one explained.
The most serious there right now: Activated Charcoal (major), Alkanna (moderate), Alpine Ragwort (moderate), Bacillus Coagulans (moderate) and Bacillus Subtilis (moderate).
By severity: 1 major · 53 moderate · 10 minor.
From our pharmacist’s overview on the Rifapentine page
“Rifapentine (Priftin) treats tuberculosis and is often dosed just once or twice a week, so a single blunted dose costs more than it would with a daily pill. That is why I read this list of 64 interacting supplements as a real warning rather than routine fine print.”
Reviewed by 2 · Jul 18, 2026
Taking Quince as Part of a Dietary Supplement Product? Check It for Interactions
We hold 25 real supplement products containing Quince, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Quince. Even though Quince itself has no known interaction with Rifapentine, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:
Where Quince and Rifapentine Sit Against Everything Else
Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.
#590 of 1,452 supplements looked up here in the last 7 days
#2,684 of 2,830 medications looked up here in the last 7 days
Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.
Where does our data come from?
- Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
- Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources.
- Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Quince and Rifapentine records this page draws on were last updated June 22, 2026.
- What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
About Quince
What is Quince?
- Digestive upset and diarrhea
- Acid reflux and heartburn
- Sore throat and cough
- Skin soothing and wound care
- Nausea
Quince is a tart, apple-like fruit traditionally used for digestive complaints, reflux, and soothing the throat and skin. Early research is interesting but limited, so quince should not replace proven treatments. Enjoying cooked quince in food is generally fine, but talk to a pharmacist or doctor before using concentrated supplements.
Cydonia oblonga · Rosaceae · Fruit, seeds, and leaves · Fresh fruit, jam or jelly, syrup, tea, dried seeds, capsules, extracts
An interaction check asks whether these two react with each other — it does not ask whether Quince is a good idea for someone in your situation. Here is what our Quince record says about it on its own.
Quince: dosing
There is no standardized or proven dose for quince supplements. The right amount depends on the product, the part of the plant used, and how it is prepared, which varies a lot between brands.If you choose to use a quince product, follow the directions on the label and do not exceed the suggested amount. Avoid eating raw or crushed seeds.
From our Quince monograph — the full record covers uses, side effects and every documented interaction.
About Rifapentine
What Is Rifapentine Used For?
Brand name: Priftin
Rifapentine tablets — sold as Priftin and as rifapentine tablets — are used to treat two forms of tuberculosis caused by Mycobacterium tuberculosis. For active pulmonary TB (a live TB infection in the lungs), it is approved for adults and children 12 years and older. It must always be combined with other anti-TB drugs — never taken alone.
For latent tuberculosis infection (LTBI) — where TB bacteria are in the body but not yet causing illness — it is approved for adults and children 2 years and older who are at high risk of the infection becoming active. For LTBI, it is always taken together with isoniazid, once weekly for 12 weeks. Active TB disease must be ruled out before starting LTBI treatment.
Most-Reported Side Effects for Rifapentine
From FAERS, the FDA’s public side-effect reporting system (509 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.
Other Drugs & Quince
Browse every other medication we’ve checked against Quince — both the ones with a known interaction and the ones without. Select any drug for the full detail.
No drugs match “”.
No interaction 2,829 drugs checked — show the list
We also checked Quince against these medications and found no known interaction in our sources. Open any page to confirm.
- Apixaban ›
- Levothyroxine ›
- Amlodipine ›
- Methylphenidate ›
- Warfarin ›
- Sertraline ›
- Testosterone ›
- Losartan Potassium ›
- Metoprolol ›
- Aspirin ›
- Ivermectin ›
- Rivaroxaban ›
- Rosuvastatin ›
- Escitalopram ›
- Tadalafil ›
- Acetaminophen ›
- Clopidogrel ›
- Valacyclovir ›
- Atorvastatin ›
- Docusate ›
- Hydroxyurea ›
- Abemaciclib ›
- Methamphetamine ›
- Ibuprofen ›
- Sumatriptan ›
- Semaglutide ›
- Tirzepatide ›
- Warfarin Sodium ›
- Prednisone ›
- Propranolol ›
- Lisdexamfetamine ›
- Acyclovir ›
- Bupropion ›
- Metformin ›
- Amoxicillin ›
- Lisinopril ›
- Bendamustine ›
- Amitriptyline ›
- Doxycycline ›
- Lamotrigine ›
- Fluoxetine ›
- Methotrexate ›
- Acetaminophen, Codeine ›
- Gabapentin ›
- Amphetamine ›
- Pregabalin ›
- Isotretinoin ›
- Dextroamphetamine ›
- Azithromycin ›
- Clonazepam ›
- Quetiapine ›
- Omeprazole ›
- Amlodipine Besylate ›
- Methylene Blue ›
- Duloxetine ›
- Buspirone ›
- Letrozole ›
- Citalopram ›
- Ciprofloxacin ›
- Naproxen ›
Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Quince list.
Sources & How We Checked
We checked Quince against Rifapentine in the Natural Medicines interaction database and found no documented interaction on file. The medication overview comes from MedlinePlus, and supplement label details from the NIH Dietary Supplement Label Database.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference for vitamins, herbs and supplements — the basis for our interaction data.
- MedlinePlus, U.S. National Library of Medicine — NIH consumer drug information, used for the medication overviews.
- NIH Dietary Supplement Label Database (DSLD) — Official supplement product labels.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC
Rifapentine Is Linked to Lower Levels of 7 Nutrients
Natural Medicines records Rifapentine as a medicine that can lower these. This is not an interaction with Quince — it is a separate effect of the medicine, and it is a reason some people are advised to supplement rather than to avoid one:
Read the full Rifapentine nutrient depletion report ›
Depletion records come from the licensed Natural Medicines database. Do not start a supplement on the strength of this page — ask your pharmacist or doctor whether it applies to you.
Taking Quince and Rifapentine Together: Common Questions
Is it safe to take Quince with Rifapentine?
Should I take Quince and Rifapentine at the same time of day?
Does Rifapentine interact with any supplements?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Still Have a Question About Rifapentine and Quince?
Our pharmacists answer your medication & supplement questions — free.
This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.