Drug & supplement interaction

Quinoa + Sacubitril, Valsartan

Sacubitril, Valsartan brand name: Entresto.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 13, 2026
The bottom line No known interaction

We found no known interaction between Quinoa and Sacubitril, Valsartan in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Quinoa and Sacubitril, Valsartan

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Sacubitril, Valsartan and Quinoa in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Quinoa at all — not against Sacubitril, Valsartan, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Quinoa safety at a glance

Quinoa overall Generally safe Quinoa is widely eaten as a food and is generally safe for most people.
Pregnancy Likely Safe When used orally in food amounts. There is insufficient reliable information available about the safety of quinoa in medicinal amounts; avoid using. Read the full pregnancy detail
Breastfeeding Likely Safe When used orally in food amounts. There is insufficient reliable information available about the safety of quinoa in medicinal amounts; avoid using. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Sacubitril, Valsartan and Quinoa? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Quinoa and Sacubitril, Valsartan May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. 2 of them are worth acting on rather than waiting out — marked below.

  • A severe allergic reaction / An allergic reaction Worth acting on Additional detail

    Quinoa

    “Orally, allergic reactions to quinoa have been reported. Anaphylaxis and pruritic reactions have occurred in at least two individuals, a 29-year-old female and a 52-year-old male. Quinoa allergy was confirmed in both patients via skin-prick testing with quinoa extract.”

    Quinoa · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    3 sources cited
    1. 99150. Hong J, Convers K, Reeves N, Temprano J. Anaphylaxis to quinoa. Ann Allergy Asthma Immunol. 2013;110(1):60-1. PubMed
    2. 96062. El-Qutob López D, Bartolomé Zavala B, Ortiz I. Cross-reactivity between buckwheat and quinoa in a patient with eosinophilic esophagitis caused by wheat. J Investig Allergol Clin Immunol. 2014;24(1):56-7.
    3. 99151. Astier C, Moneret-Vautrin DA, Puillandre E, Bihain BE. First case report of anaphylaxis to quinoa, a novel food in France. Allergy. 2009;64(5):819-20. PubMed

    Sacubitril, Valsartan

    Listed in the ADVERSE REACTIONS section of the FDA label for Sacubitril, Valsartan. Read the label on DailyMed ›

Effects for Sacubitril, Valsartan come from the ADVERSE REACTIONS section of its FDA label; effects for Quinoa come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Quinoa in Pregnancy & Breastfeeding

Pregnancy And Lactation Likely Safe

When used orally in food amounts. There is insufficient reliable information available about the safety of quinoa in medicinal amounts; avoid using.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Sacubitril, Valsartan

This page covers Quinoa only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Sacubitril, Valsartan page lists 249 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Lithium (major) and Oleander (major).

By severity: 7 major · 206 moderate · 36 minor.

From our pharmacist’s overview on the Sacubitril, Valsartan page

“Entresto (sacubitril and valsartan) is a heart failure medicine, and heart failure patients tend to be heavy supplement users, reaching for fish oil, potassium, and herbal blood-pressure remedies. That instinct carries real risk here.”

Reviewed by 2 · Jul 18, 2026

Open the Sacubitril, Valsartan interaction page

One more smart check

Taking Quinoa as Part of a Dietary Supplement Product? Check It for Interactions

We hold 699 real supplement products containing Quinoa, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Quinoa. Even though Quinoa itself has no known interaction with Sacubitril, Valsartan, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Quinoa and Sacubitril, Valsartan Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Quinoa
Top 25%

#286 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Sacubitril, Valsartan
Top 25%

#330 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Quinoa reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Quinoa and Sacubitril, Valsartan records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Quinoa

What is Quinoa?

  • Gluten-free grain alternative
  • Plant-based protein source
  • Heart and cholesterol health
  • Blood sugar support
  • Digestive and fiber intake
  • Weight management

Quinoa is a nutritious, gluten-free seed eaten like a grain, rich in protein, fiber, and minerals. It is best thought of as a healthy food rather than a medicine, and most people can enjoy it safely as part of a balanced diet.

Chenopodium quinoa · Amaranthaceae · Seeds (whole grain); leaves are sometimes eaten as a vegetable · Whole cooked seeds, flour, flakes, puffed cereal, and protein powders

An interaction check asks whether these two react with each other — it does not ask whether Quinoa is a good idea for someone in your situation. Here is what our Quinoa record says about it on its own.

Quinoa: dosing

There is no official medicinal dose for quinoa because it is a food, not a standardized supplement. Most people simply eat it as a serving of cooked grain, similar to rice or pasta.If you use a quinoa-based product such as flour, flakes, or a protein powder, follow the directions on the package.

From our Quinoa monograph — the full record covers uses, side effects and every documented interaction.

Read the full Quinoa monograph & all interactions
Medication

About Valsartan and Sacubitril

What Is Valsartan and Sacubitril Used For?

Brand name: Entresto

Sacubitril and valsartan is used to reduce the risk of cardiovascular death and hospitalization for heart failure in adult patients with chronic heart failure. The benefit is most clearly seen in patients whose heart pumps with a lower-than-normal ejection fraction (the percentage of blood the heart pushes out with each beat).

It is also approved to treat symptomatic heart failure with reduced left ventricular function in children aged 1 year and older. In pediatric patients, it lowers a blood marker of heart stress (NT-proBNP) and is expected to improve heart outcomes.

See full Valsartan and Sacubitril drug information
Keep checking

Other Drugs & Quinoa

Browse every other medication we’ve checked against Quinoa — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Quinoa against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Quinoa list.

See the full Quinoa interactions page
See every supplement checked against Sacubitril, Valsartan, ranked by severity
Evidence & sources

Quinoa References

The 5 references that drive our Quinoa monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. El-Qutob López D, Bartolomé Zavala B, Ortiz I. Cross-reactivity between buckwheat and quinoa in a patient with eosinophilic esophagitis caused by wheat. J Investig Allergol Clin Immunol. 2014;24(1):56-7.
  2. Li L, Lietz G, Bal W, Watson A, Morfey B, Seal C. Effects of quinoa (Chenopodium quinoa Willd.) consumption on markers of CVD risk. Nutrients. 2018;10(6). pii: E777. PubMed
  3. De Carvalho FG, Ovídio PP, Padovan GJ, Jordão Junior AA, Marchini JS, Navarro AM. Metabolic parameters of postmenopausal women after quinoa or corn flakes intake--a prospective and double-blind study. Int J Food Sci Nutr. 2014;65(3):380-5. PubMed
  4. Hong J, Convers K, Reeves N, Temprano J. Anaphylaxis to quinoa. Ann Allergy Asthma Immunol. 2013;110(1):60-1. PubMed
  5. Astier C, Moneret-Vautrin DA, Puillandre E, Bihain BE. First case report of anaphylaxis to quinoa, a novel food in France. Allergy. 2009;64(5):819-20. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Quinoa and Sacubitril, Valsartan Together: Common Questions

Is it safe to take Quinoa with Sacubitril, Valsartan?
We do not list a known interaction between Quinoa and Sacubitril, Valsartan. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Quinoa and Sacubitril, Valsartan have any of the same side effects?
Yes — our sources link each of them separately to 2 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Sacubitril, Valsartan interact with any supplements?
Yes. Sacubitril, Valsartan has documented interactions with 249 supplements in our database — Quinoa is not one of them. The Sacubitril, Valsartan interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Quinoa monograph Uses, safety profile, and every drug interaction in one place Valsartan and Sacubitril drug information The full plain-English guide to this medication Sacubitril, Valsartan supplement interactions Every supplement checked against Sacubitril, Valsartan, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 5 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Sacubitril, Valsartan and Quinoa?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.