Drug & supplement interaction

Raw Food Diet + Riluzole

Riluzole brand names: Rilutek, Tiglutik, Exservan.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Raw Food Diet and Riluzole in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Raw Food Diet and Riluzole

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Riluzole and Raw Food Diet in our sources. This does not guarantee that the combination is completely free of risk — research on Raw Food Diet alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Raw Food Diet at all — not against Riluzole, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Raw Food Diet is an eating pattern rather than something you take. Ask your pharmacist or doctor before changing how you eat while on a prescribed medicine: some medicines are dosed around meals, and a change in diet can change how they work. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Raw Food Diet safety at a glance

Raw Food Diet overall Use caution It can lead to nutrient gaps and foodborne illness if not carefully planned.
Pregnancy Possibly Unsafe During pregnancy and lactation due to risk for malnutrition. Read the full pregnancy detail
Breastfeeding Possibly Unsafe During pregnancy and lactation due to risk for malnutrition. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Riluzole and Raw Food Diet? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Raw Food Diet and Riluzole May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so following Raw Food Diet while taking the medicine can make those effects more likely to turn up, and harder to pin on one or the other if they do.

  • Tiredness / Vomiting / Nausea Additional detail

    Raw Food Diet

    “In one clinical study, patients following a 40% raw food diet reported nausea, vomiting, and malaise after consuming typical restaurant and banquet foods. Participants also reported gastrointestinal symptoms when consuming certain foods, such as citrus fruit, nuts, and tomatoes.”

    Raw Food Diet · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 103158. Douglass JM, Rasgon IM, Fleiss PM, Schmidt RD, Peters SN, Abelmann EA. Effects of a raw food diet on hypertension and obesity. South Med J. 1985 Jul;78(7):841-4. PubMed

    Riluzole

    Listed in the ADVERSE REACTIONS section of the FDA label for Riluzole. Read the label on DailyMed ›

Reported for Raw Food Diet but not commonly for Riluzole: changes to your period.

Effects for Riluzole come from the ADVERSE REACTIONS section of its FDA label; effects for Raw Food Diet come from the Natural Medicines adverse-effect record, quoted above. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Special populations

Raw Food Diet in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

During pregnancy and lactation due to risk for malnutrition.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Everything else you take

See Every Supplement That Interacts With Riluzole

This page covers Raw Food Diet only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Riluzole page lists 141 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Beer (major), Siberian Cocklebur (major), Wine (major) and Adrafinil (moderate).

By severity: 4 major · 106 moderate · 31 minor.

From our pharmacist’s overview on the Riluzole page

“Riluzole (Rilutek, Tiglutik, Exservan) slows the progression of ALS, and it already works the liver hard, which is where this list turns genuinely serious. The four major-rated entries among 141 documented interactions cluster around two hazards: extra liver strain (Siberian cocklebur has caused liver failure, and heavy alcohol from be…”

Reviewed by 2 · Jul 18, 2026

Open the Riluzole interaction page

How much people look this up

Where Raw Food Diet and Riluzole Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Raw Food Diet
Steady interest

#1,411 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Riluzole
Steady interest

#1,610 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Raw Food Diet reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Raw Food Diet and Riluzole records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Eating pattern

About Raw Food Diet

What is Raw Food Diet?

  • Weight loss
  • Improving digestion
  • Increasing fruit and vegetable intake
  • General wellness and detox
  • Lowering cholesterol

A raw food diet emphasizes uncooked, unprocessed plant foods (and sometimes raw animal products) based on the idea that cooking destroys nutrients and enzymes. It can boost intake of fruits and vegetables and help with weight loss, but it carries real risks of nutrient deficiencies and foodborne illness. Talk with a doctor or dietitian before trying it, especially if you are pregnant, breastfeeding, or have a health condition.

Whole eating pattern based on uncooked or minimally heated plant foods, fruits, vegetables, nuts, seeds, and sprouted grains

An interaction check asks whether these two react with each other — it does not ask whether Raw Food Diet is a good idea for someone in your situation. Here is what our Raw Food Diet record says about it on its own.

Raw Food Diet: dosing

Because a raw food diet is an eating pattern and not a pill, there is no standardized 'dose.' Plans vary widely—some people eat 100% raw, while others aim for 75% or 50% raw and cook the rest.If you want to try it, a safer approach is to add more raw fruits and vegetables to your meals rather than switching to fully raw all at once. Working with a registered dietitian helps you plan for protein, vitamin B12, vitamin D, calcium, iron, and omega-3 fats, and may include supplements to fill gaps.

From our Raw Food Diet monograph — the full record covers uses, side effects and every documented interaction.

Read the full Raw Food Diet monograph & all interactions
Medication

About Riluzole

What Is Riluzole Used For?

Brand names: Rilutek, Tiglutik, Exservan

Riluzole is approved to treat amyotrophic lateral sclerosis (ALS) — the progressive neurological disease also known as Lou Gehrig's disease. This indication is shared across all available riluzole products, including tablets (Rilutek, riluzole), the dissolving oral film (Exservan), and the oral suspension (Tiglutik).

Tiglutik oral suspension is notable in that it can also be given through a PEG-tube (percutaneous endoscopic gastrostomy tube) for patients who have difficulty swallowing.

See full Riluzole drug information
Keep checking

Other Drugs & Raw Food Diet

Browse every other medication we’ve checked against Raw Food Diet — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Raw Food Diet References

The 4 references that drive our Raw Food Diet monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Koebnick C, Garcia AL, Dagnelie PC, et al. Long-term consumption of a raw food diet is associated with favorable serum LDL cholesterol and triglycerides but also with elevated plasma homocysteine and low serum HDL cholesterol in humans. J Nutr. 2005 Oct;1
  2. Koebnick C, Strassner C, Hoffmann I, Leitzmann C. Consequences of a long-term raw food diet on body weight and menstruation: results of a questionnaire survey. Ann Nutr Metab. 1999;43(2):69-79. PubMed
  3. Ganss C, Schlechtriemen M, Klimek J. Dental erosions in subjects living on a raw food diet. Caries Res. 1999;33(1):74-80. PubMed
  4. Douglass JM, Rasgon IM, Fleiss PM, Schmidt RD, Peters SN, Abelmann EA. Effects of a raw food diet on hypertension and obesity. South Med J. 1985 Jul;78(7):841-4. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Following Raw Food Diet While Taking Riluzole: Common Questions

Is it safe to follow Raw Food Diet while taking Riluzole?
We do not list a known interaction between Raw Food Diet and Riluzole. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Raw Food Diet and Riluzole have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Does Riluzole interact with any supplements?
Yes. Riluzole has documented interactions with 141 supplements in our database — Raw Food Diet is not one of them. The Riluzole interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Riluzole and Raw Food Diet?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.