Drug & supplement interaction

Raw Food Diet + Unoprostone

Unoprostone brand name: Rescula.

No Known Interaction
Medically reviewed by · Updated July 2026 · Pair last verified Sep 20, 2026
The bottom line No known interaction

We found no known interaction between Raw Food Diet and Unoprostone in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Raw Food Diet and Unoprostone

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Unoprostone and Raw Food Diet in our sources. This does not guarantee that the combination is completely free of risk — research on Raw Food Diet alongside specific medications may be limited.

Worth understanding: our licensed dataset holds no drug-interaction record for Raw Food Diet at all — not against Unoprostone, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

Raw Food Diet is an eating pattern rather than something you take. Ask your pharmacist or doctor before changing how you eat while on a prescribed medicine: some medicines are dosed around meals, and a change in diet can change how they work. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Raw Food Diet safety at a glance

Raw Food Diet overall Use caution It can lead to nutrient gaps and foodborne illness if not carefully planned.
Pregnancy Possibly Unsafe During pregnancy and lactation due to risk for malnutrition. Read the full pregnancy detail
Breastfeeding Possibly Unsafe During pregnancy and lactation due to risk for malnutrition. Read the full breastfeeding detail

Pregnancy & breastfeeding ratings are from Natural Medicines (Therapeutic Research Center) — the full detail is in the Special populations card below. Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Unoprostone and Raw Food Diet? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

What Raw Food Diet Itself Has Been Linked To

This is not an interaction — nothing below involves Unoprostone. It is the side-effect record for Raw Food Diet on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Raw Food Diet, this list is the first place to look.

  • Changes to your period Additional detail

    “When followed with strict adherence, raw food diets may not provide adequate nutrition. Observational research in long-term adherents of raw food diets found that 15% of men and 25% of women had a body mass index (BMI) below the normal weight range. Those with strict adherence had an increased risk for a low BMI.”

    Raw Food Diet · Natural Medicines adverse-effect record, reported in amenorrhea.

    4 sources cited
    1. 103156. Koebnick C, Strassner C, Hoffmann I, Leitzmann C. Consequences of a long-term raw food diet on body weight and menstruation: results of a questionnaire survey. Ann Nutr Metab. 1999;43(2):69-79. PubMed
    2. 103155. Koebnick C, Garcia AL, Dagnelie PC, et al. Long-term consumption of a raw food diet is associated with favorable serum LDL cholesterol and triglycerides but also with elevated plasma homocysteine and low serum HDL cholesterol in humans. J Nutr. 2005 Oct;1
    3. 103157. Ganss C, Schlechtriemen M, Klimek J. Dental erosions in subjects living on a raw food diet. Caries Res. 1999;33(1):74-80. PubMed
    4. 103158. Douglass JM, Rasgon IM, Fleiss PM, Schmidt RD, Peters SN, Abelmann EA. Effects of a raw food diet on hypertension and obesity. South Med J. 1985 Jul;78(7):841-4. PubMed

    “An observational study of long-term raw food diet adherents found that 30% of women had partial or complete amenorrhea. The rate of amenorrhea was higher in women with strict adherence to the diet than in those who followed a moderate raw food diet.”

    Raw Food Diet · Natural Medicines adverse-effect record, reported in amenorrhea.

    1 source cited
    1. 103156. Koebnick C, Strassner C, Hoffmann I, Leitzmann C. Consequences of a long-term raw food diet on body weight and menstruation: results of a questionnaire survey. Ann Nutr Metab. 1999;43(2):69-79. PubMed
  • Tiredness / Vomiting / Nausea Additional detail

    “In one clinical study, patients following a 40% raw food diet reported nausea, vomiting, and malaise after consuming typical restaurant and banquet foods. Participants also reported gastrointestinal symptoms when consuming certain foods, such as citrus fruit, nuts, and tomatoes.”

    Raw Food Diet · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    1 source cited
    1. 103158. Douglass JM, Rasgon IM, Fleiss PM, Schmidt RD, Peters SN, Abelmann EA. Effects of a raw food diet on hypertension and obesity. South Med J. 1985 Jul;78(7):841-4. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Raw Food Diet — expand a row for the licensed statement it rests on. We haven’t matched Unoprostone to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Unoprostone.

Special populations

Raw Food Diet in Pregnancy & Breastfeeding

Pregnancy And Lactation Possibly Unsafe

During pregnancy and lactation due to risk for malnutrition.

DISCLAIMER: This tool is intended for informational purposes only, and should not be interpreted as specific medical advice. Patients should consult with a qualified healthcare provider before making decisions about therapies and/or health conditions.© 2026 Therapeutic Research Center

Overlapping uses

What Unoprostone Is Prescribed For, and What Raw Food Diet Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Unoprostone is a prescription medicine with approved uses on its FDA label. Raw Food Diet is an eating pattern: what follows is what researchers have looked at it for, and how strong that evidence is.

Raw Food Diet has been studied for:

  • Hypertension studied, not established Raw Food Diet has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Raw Food Diet for hypertension

    In a small clinical study in adults with hypertension, following a 40% raw food diet reduced diastolic blood pressure by an average 18 mmHg when compared with baseline. The investigators did not report on changes in systolic blood pressure. Dieters also experienced an average 3.8 kg weight loss. The validity of these findings is limited by the lack of a comparator group.

    1 source cited
    1. 103158. Douglass JM, Rasgon IM, Fleiss PM, Schmidt RD, Peters SN, Abelmann EA. Effects of a raw food diet on hypertension and obesity. South Med J. 1985 Jul;78(7):841-4. PubMed

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Unoprostone on your own; if you are taking Raw Food Diet for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

Everything else you take

See Every Supplement That Interacts With Unoprostone

This page covers Raw Food Diet only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Unoprostone page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

From our pharmacist’s overview on the Unoprostone page

“Unoprostone (Rescula) is a glaucoma eye drop, yet every one of the 17 supplements flagged against it works in the digestive tract, and one of them warrants genuine care. Activated charcoal, the lone major-rated entry, binds medications and can lower their levels even when a drug is not swallowed, so the eye drop route does not automati…”

Reviewed by 2 · Jul 18, 2026

Open the Unoprostone interaction page

How much people look this up

Where Raw Food Diet and Unoprostone Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Raw Food Diet
Steady interest

#833 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Unoprostone
Steady interest

#2,705 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Raw Food Diet reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Raw Food Diet and Unoprostone records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Eating pattern

About Raw Food Diet

What is Raw Food Diet?

  • Weight loss
  • Improving digestion
  • Increasing fruit and vegetable intake
  • General wellness and detox
  • Lowering cholesterol

A raw food diet emphasizes uncooked, unprocessed plant foods (and sometimes raw animal products) based on the idea that cooking destroys nutrients and enzymes. It can boost intake of fruits and vegetables and help with weight loss, but it carries real risks of nutrient deficiencies and foodborne illness. Talk with a doctor or dietitian before trying it, especially if you are pregnant, breastfeeding, or have a health condition.

Whole eating pattern based on uncooked or minimally heated plant foods, fruits, vegetables, nuts, seeds, and sprouted grains

An interaction check asks whether these two react with each other — it does not ask whether Raw Food Diet is a good idea for someone in your situation. Here is what our Raw Food Diet record says about it on its own.

Raw Food Diet: dosing

Because a raw food diet is an eating pattern and not a pill, there is no standardized 'dose.' Plans vary widely—some people eat 100% raw, while others aim for 75% or 50% raw and cook the rest.If you want to try it, a safer approach is to add more raw fruits and vegetables to your meals rather than switching to fully raw all at once. Working with a registered dietitian helps you plan for protein, vitamin B12, vitamin D, calcium, iron, and omega-3 fats, and may include supplements to fill gaps.

From our Raw Food Diet monograph — the full record covers uses, side effects and every documented interaction.

Read the full Raw Food Diet monograph & all interactions
Medication

About Unoprostone Ophthalmic

What Is Unoprostone Ophthalmic Used For?

Brand name: Rescula

  • Unoprostone ophthalmic is used to treat glaucoma (a condition in which increased pressure in the eye can lead to gradual loss of vision) and ocular hypertension (a condition which causes increased pressure in the eye). It is in a class of medications called prostaglandin analogs. Unoprostone lowers pressure in the eye by increasing the flow of natural eye fluids out of the eye.

See full Unoprostone Ophthalmic drug information
Keep checking

Other Drugs & Raw Food Diet

Browse every other medication we’ve checked against Raw Food Diet — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
2,829 No interaction
No interaction 2,829 drugs checked — show the list

We also checked Raw Food Diet against these medications and found no known interaction in our sources. Open any page to confirm.

Showing the 60 most looked-up of 2,829 medications checked with no known interaction — see the full Raw Food Diet list.

See the full Raw Food Diet interactions page
See every supplement checked against Unoprostone, ranked by severity
Evidence & sources

Raw Food Diet References

The 4 references that drive our Raw Food Diet monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Koebnick C, Garcia AL, Dagnelie PC, et al. Long-term consumption of a raw food diet is associated with favorable serum LDL cholesterol and triglycerides but also with elevated plasma homocysteine and low serum HDL cholesterol in humans. J Nutr. 2005 Oct;1
  2. Koebnick C, Strassner C, Hoffmann I, Leitzmann C. Consequences of a long-term raw food diet on body weight and menstruation: results of a questionnaire survey. Ann Nutr Metab. 1999;43(2):69-79. PubMed
  3. Ganss C, Schlechtriemen M, Klimek J. Dental erosions in subjects living on a raw food diet. Caries Res. 1999;33(1):74-80. PubMed
  4. Douglass JM, Rasgon IM, Fleiss PM, Schmidt RD, Peters SN, Abelmann EA. Effects of a raw food diet on hypertension and obesity. South Med J. 1985 Jul;78(7):841-4. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Following Raw Food Diet While Taking Unoprostone: Common Questions

Is it safe to follow Raw Food Diet while taking Unoprostone?
We do not list a known interaction between Raw Food Diet and Unoprostone. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Are Raw Food Diet and Unoprostone used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Raw Food Diet in each. That is a conversation for your prescriber, especially if Unoprostone is being adjusted to a target.
Does Unoprostone interact with any supplements?
Yes. Unoprostone has documented interactions with 17 supplements in our database — Raw Food Diet is not one of them. The Unoprostone interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

Keep Exploring

Raw Food Diet monograph Uses, safety profile, and every drug interaction in one place Unoprostone Ophthalmic drug information The full plain-English guide to this medication Unoprostone supplement interactions Every supplement checked against Unoprostone, ranked by severity Supplement interaction checker Check any supplement or product against your medications Browse medications A–Z Every drug we’ve checked against herbs & supplements References The 4 citations behind this page Ask a pharmacist Free, personal answer from our licensed team

Still Have a Question About Unoprostone and Raw Food Diet?

Our pharmacists answer your medication & supplement questions — free.

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.