Drug & supplement interaction

Smartweed + Interferon Beta-1b

Interferon Beta-1b brand names: Betaseron, Betaferon, Extavia.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Smartweed and Interferon Beta-1b in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Smartweed and Interferon Beta-1b

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Interferon Beta-1b and Smartweed in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Smartweed safety at a glance

Smartweed overall Use caution There is little modern safety data, so use cautiously and talk to a healthcare provider first.
Pregnancy Avoid Traditionally used to affect menstruation and the uterus, so avoid during pregnancy.
Breastfeeding Avoid There is not enough safety information, so it is best to avoid while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Interferon Beta-1b and Smartweed? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Interferon Beta-1b

Interactions in our licensed database are recorded against drug classes, not just single drug names. Interferon Beta-1b is filed under 2 classifications — photosensitizing drugs, hepatotoxic drugs. Smartweed has documented interactions with 1 drug class — the most serious being warfarin (coumadin) (moderate) — and none of Interferon Beta-1b’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Smartweed Does Interact With Other Medications

Smartweed has 2 moderate known drug interactions in our database — Interferon Beta-1b isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Smartweed

Covers the 2,830 medications we’ve checked against Smartweed. Pick one to open its full report.

Everything else you take

See Every Supplement That Interacts With Interferon Beta-1b

This page covers Smartweed only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Interferon Beta-1b page lists 57 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Beer (major), Siberian Cocklebur (major), Wine (major), Alfalfa (moderate) and Angelica Archangelica (moderate).

By severity: 3 major · 53 moderate · 1 minor.

From our pharmacist’s overview on the Interferon Beta-1b page

“If you inject interferon beta-1b (Betaseron, Betaferon, Extavia) for multiple sclerosis, this supplement list is one to take seriously, mostly because of your liver. Interferon beta-1b can raise liver enzymes on its own, and 38 of the 57 ingredients on file add their own liver stress on top of that.”

Reviewed by 2 · Jul 18, 2026

Open the Interferon Beta-1b interaction page

One more smart check

Taking Smartweed as Part of a Dietary Supplement Product? Check It for Interactions

We hold 4 real supplement products containing Smartweed, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Smartweed. Even though Smartweed itself has no known interaction with Interferon Beta-1b, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Smartweed and Interferon Beta-1b Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Smartweed
Steady interest

#771 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Interferon Beta-1b
Steady interest

#2,299 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Smartweed reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 20, 2026. The Smartweed and Interferon Beta-1b records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Smartweed

What is Smartweed?

Smartweed
  • Digestive upset
  • Minor skin irritation
  • Heavy menstrual bleeding (traditional)
  • Wound and bleeding (traditional topical use)
  • Antioxidant and anti-inflammatory support

Smartweed (Persicaria hydropiper) is a peppery wetland plant with a long history in traditional medicine for digestive complaints, bleeding, and skin problems. Modern human studies are very limited, so its benefits are not well proven. Because safety data are thin, it's best to use cautiously and avoid it during pregnancy and breastfeeding.

Persicaria hydropiper · Polygonaceae · Aerial parts (leaves, stems, and flowering tops); sometimes the whole plant · Tea, tincture, liquid extract, dried herb, and topical preparations

An interaction check asks whether these two react with each other — it does not ask whether Smartweed is a good idea for someone in your situation. Here is what our Smartweed record says about it on its own.

Smartweed: dosing

There is no well-established or standardized dose for smartweed. Because it has not been carefully studied in people, experts cannot recommend a safe and effective amount.If you choose to use a product, follow the directions on the label and do not exceed them.

From our Smartweed monograph — the full record covers uses, side effects and every documented interaction.

Read the full Smartweed monograph & all interactions
Medication

About Interferon Beta-1b Injection

What Is Interferon Beta-1b Injection Used For?

Brand names: Betaseron, Betaferon, Extavia

  • Interferon beta-1b injection is used to reduce episodes of symptoms in patients with relapsing-remitting (course of disease where symptoms flare up from time to time) of multiple sclerosis (MS, a disease in which the nerves do not function properly and patients may experience weakness, numbness, loss of muscle coordination and problems with vision, speech, and bladder control). Interferon beta-1b is in a class of medications called immunomodulators. It is not known exactly how interferon beta-1b works to treat MS.

Most-Reported Side Effects for Interferon Beta-1b

From FAERS, the FDA’s public side-effect reporting system (19,057 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Influenza like illness 1,402 reports
Multiple sclerosis relapse 1,344 reports
Fatigue 1,198 reports
Injection site pain 1,198 reports
Multiple sclerosis 1,167 reports
See full Interferon Beta-1b Injection drug information
Keep checking

Other Drugs & Smartweed

Browse every other medication we’ve checked against Smartweed — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
2Moderate
0Minor
2,827No known interaction
Moderate

2 interactions

No interaction 2,827 drugs checked — show the list
Evidence & sources

Smartweed References

The 2 references that drive our Smartweed monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Smartweed and Interferon Beta-1b Together: Common Questions

Is it safe to take Smartweed with Interferon Beta-1b?
We do not list a known interaction between Smartweed and Interferon Beta-1b. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Smartweed and Interferon Beta-1b combination checked?
Interactions in our licensed database are recorded against drug classes. Interferon Beta-1b is filed under 2 classifications, and Smartweed has documented interactions with 1 drug class — none of Interferon Beta-1b's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Smartweed interact with any other medications?
Yes. Smartweed has 2 documented drug interactions in our database — Interferon Beta-1b is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Interferon Beta-1b interact with any supplements?
Yes. Interferon Beta-1b has documented interactions with 57 supplements in our database — Smartweed is not one of them. The Interferon Beta-1b interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Interferon Beta-1b and Smartweed?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.