Drug & supplement interaction

Storax + Acetaminophen

Acetaminophen brand names: Tylenol Ex Strength, Children's Tylenol, Tylenol, Children's Tylenol Meltaways.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Storax and Acetaminophen in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first. Additionally, although there is no interaction, the two are separately associated with some of the same side effects, which would make a new symptom harder to attribute to one or the other.

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Interaction report

Storax and Acetaminophen

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Acetaminophen and Storax in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

Worth understanding: our licensed dataset holds no drug-interaction record for Storax at all — not against Acetaminophen, and not against any other medication we track. This verdict therefore rests on the absence of any recorded data, not on research that looked at this combination and found nothing. We cannot rule an interaction out.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Storax safety at a glance

Storax overall Use caution Generally used topically or as a flavoring in small amounts, but it can irritate skin and trigger allergic reactions.
Pregnancy Avoid There is not enough safety data, so it is best avoided during pregnancy.
Breastfeeding Avoid Safety while breastfeeding is unknown, so avoidance is the cautious choice.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Acetaminophen and Storax? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
What to actually watch for

No Interaction Found — But Data Suggests Storax and Acetaminophen May Share Several of the Same Side Effects

This is not an interaction. Neither one changes how your body handles the other, and nothing here says they react together. What our sources do show is that each has separately been linked to the effects below — so taking both can make those effects more likely to turn up, and harder to pin on one or the other if they do. 2 of them are worth acting on rather than waiting out — marked below.

  • Kidney problems Worth acting on Additional detail

    Storax

    “When applied to large, open wounds, systemic absorption of storax can cause kidney damage (e.g., albuminuria and hemorrhagic nephritis) (18).”

    Storax · Natural Medicines adverse-effect record, reported in albuminuria.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Acetaminophen

    Listed in the ADVERSE REACTIONS section of the FDA label for Acetaminophen. Read the label on DailyMed ›

  • An allergic reaction Worth acting on Additional detail

    Storax

    Recorded for Storax in the same Natural Medicines adverse-effect record shown under Kidney problems above.

    Acetaminophen

    Listed in the ADVERSE REACTIONS section of the FDA label for Acetaminophen. Read the label on DailyMed ›

  • Diarrhea Additional detail

    Storax

    “Orally, storax can cause diarrhea (18).”

    Storax · Natural Medicines adverse-effect record, reported in diarrhea.

    1 source cited
    1. 18. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

    Acetaminophen

    Listed in the ADVERSE REACTIONS section of the FDA label for Acetaminophen. Read the label on DailyMed ›

Effects for Acetaminophen come from the ADVERSE REACTIONS section of its FDA label; effects for Storax come from the Natural Medicines adverse-effect record, quoted above. Where a percentage is shown, it is the share of 679,604 voluntary FDA FAERS reports for Acetaminophen that mention that effect — a reporting proportion, not an incidence rate and not evidence the drug caused it. Wording is matched across sources by our own clinical vocabulary, so treat this as a prompt to pay attention, not a diagnosis.

Overlapping uses

What Acetaminophen Is Prescribed For, and What Storax Has Been Studied For

These two come up together because they touch the same health topic — not because they do the same job. Acetaminophen is a prescription medicine with approved uses on its FDA label. Storax is a supplement: what follows is what researchers have looked at it for, and how strong that evidence is.

Acetaminophen is prescribed for: Acetaminophen temporarily relieves minor aches and pains caused by headaches, the common cold, backaches, muscle aches, toothaches, minor arthritis pain, and premenstrual or menstrual cramps. It also temporarily reduces fever. These uses apply across oral tablet, suspension, and oral liquid products. The intravenous (IV) injection form is used in clinical settings to treat acute pain and fever, including in pediatric patients 2 years and older.

Storax has been studied for:

  • Common cold studied, not established Storax has been studied for this. Natural Medicines rates the evidence: Insufficient Reliable Evidence To Rate Read what the research shows

    Storax for common cold

    Although there has been interest in using oral storax for the common cold, there is insufficient reliable information about the clinical effects of storax for this purpose.

Effectiveness ratings and the research summaries above are the verbatim record from the Natural Medicines database, which grades evidence from “Effective” down to “Insufficient Reliable Evidence To Rate”. A rating below the top of that scale means researchers have looked at it — not that it works, and never that it can stand in for a prescribed medicine. Do not stop or replace Acetaminophen on your own; if you are taking Storax for the same health topic, tell your prescriber, especially if the medicine is being adjusted to a target.

From our Q&A

Questions About Storax or Acetaminophen

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Storax or Acetaminophen, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Acetaminophen

This page covers Storax only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Acetaminophen page lists 155 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Asarabacca (major), Beer (major), Siberian Cocklebur (major) and Wine (major).

By severity: 5 major · 114 moderate · 36 minor.

From our pharmacist’s overview on the Acetaminophen page

“Acetaminophen (Tylenol) feels harmless because it sits on every shelf, but this list deserves real attention, mostly because of your liver. Of the 155 supplements and herbs on file, five carry a major rating, and the largest serious group, 38 ingredients, adds liver strain on top of acetaminophen's own well-known potential to harm the…”

Reviewed by 2 · Jul 18, 2026

Open the Acetaminophen interaction page

One more smart check

Taking Storax as Part of a Dietary Supplement Product? Check It for Interactions

We hold 24 real supplement products containing Storax, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Storax. Even though Storax itself has no known interaction with Acetaminophen, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Storax and Acetaminophen Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Storax
Steady interest

#1,049 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Acetaminophen
Top 1%

#25 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Storax reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Storax and Acetaminophen records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Storax

What is Storax?

  • Skin wounds and scabies
  • Cough and respiratory complaints
  • As a topical antiseptic
  • Fragrance and incense
  • Flavoring agent

Storax is an aromatic balsam (resin) tapped from Liquidambar trees, used traditionally as a topical antiseptic, a remedy for skin parasites, and a respiratory aid. Modern human evidence for its health benefits is very limited, and it can cause skin irritation or allergic reactions, so use it cautiously and check with a pharmacist or doctor first.

Liquidambar orientalis · Altingiaceae · Balsam (resin) from the trunk bark · Balsam (resin), tincture, topical ointments and creams, incense, and an ingredient in compound preparations like Friar's Balsam

An interaction check asks whether these two react with each other — it does not ask whether Storax is a good idea for someone in your situation. Here is what our Storax record says about it on its own.

Storax: dosing

There is no well-established standardized dose for storax, and it has not been studied in the kind of rigorous trials needed to recommend specific amounts. It is most often used topically or as a small flavoring ingredient rather than as an oral supplement.If you use a product that contains storax, follow the directions on the label and do not exceed the recommended amount.

From our Storax monograph — the full record covers uses, side effects and every documented interaction.

Read the full Storax monograph & all interactions
Medication

About Acetaminophen

What Is Acetaminophen Used For?

Brand names: Tylenol Ex Strength, Children's Tylenol, Tylenol, Children's Tylenol Meltaways

Acetaminophen temporarily relieves minor aches and pains caused by headaches, the common cold, backaches, muscle aches, toothaches, minor arthritis pain, and premenstrual or menstrual cramps. It also temporarily reduces fever.

These uses apply across oral tablet, suspension, and oral liquid products. The intravenous (IV) injection form is used in clinical settings to treat acute pain and fever, including in pediatric patients 2 years and older.

Most-Reported Side Effects for Acetaminophen

From FAERS, the FDA’s public side-effect reporting system (679,604 reports, all brands). Reports are voluntary and are not proof the drug caused the effect.

Fatigue 45,791 reports
Nausea 41,932 reports
Overdose 40,941 reports
Drug dependence 39,209 reports
Headache 38,738 reports
See full Acetaminophen drug information
Keep checking

Other Drugs & Storax

Browse every other medication we’ve checked against Storax — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
0Moderate
0Minor
2,829No known interaction
No interaction 2,829 drugs checked — show the list
Evidence & sources

Storax References

The 2 references that drive our Storax monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Martindale W. Martindale the Extra Pharmacopoeia. Pharmaceutical Press, 1999.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Storax and Acetaminophen Together: Common Questions

Is it safe to take Storax with Acetaminophen?
We do not list a known interaction between Storax and Acetaminophen. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
Do Storax and Acetaminophen have any of the same side effects?
Yes — our sources link each of them separately to 3 of the same effects. That is not an interaction: neither changes how your body handles the other. It does mean that if one of those effects turns up, it can be harder to tell which one is behind it. They are listed on this page with the source behind each.
Are Storax and Acetaminophen used for the same thing?
They overlap in purpose, which usually means the real question is whether you need both rather than whether they are safe together. This page lists the shared uses and how strong the evidence is for Storax in each. That is a conversation for your prescriber, especially if Acetaminophen is being adjusted to a target.
Does Acetaminophen interact with any supplements?
Yes. Acetaminophen has documented interactions with 155 supplements in our database — Storax is not one of them. The Acetaminophen interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Acetaminophen and Storax?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.