Drug & supplement interaction

Strawberry + Docusate

Docusate brand name: Colace.

No Known Interaction
The bottom line No known interaction

We found no known interaction between Strawberry and Docusate in our sources. Absence of a documented interaction is not the same as proven safety, and does not guarantee one does not exist. Do not start, stop, or change a medication or supplement based on this page; confirm with your pharmacist or doctor first.

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Interaction report

Strawberry and Docusate

We checked these two against our interaction database. Here is what we found.

No Known Interaction Found

We did not find a documented interaction between Docusate and Strawberry in our sources. This does not guarantee that the combination is completely free of risk — there is often limited research on supplements and herbal products, especially around drug interactions.

If you decide to take both, the practical routine is simple: add one new thing at a time and note the date you started it. If the combination is going to disagree with you, it usually shows in the first days to a couple of weeks — and a start date turns “I’ve been feeling off” into something a pharmacist can actually work with. Do not stop a prescribed medicine on your own.

Always talk with your pharmacist or doctor before making changes to your medications or supplements, particularly if you take several medications or have an ongoing health condition.

Strawberry safety at a glance

Strawberry overall Generally safe Strawberry fruit is widely eaten and considered safe for most people in normal food amounts.
Pregnancy Use caution Eating strawberries as food is generally fine, but concentrated supplement doses are not well studied in pregnancy.
Breastfeeding Use caution Strawberries as food are generally fine, but concentrated supplements lack safety data while breastfeeding.

Safety guidance is general; always confirm with your pharmacist or doctor for your situation.

Still wondering about combining Docusate and Strawberry? Ask Dr. Brian Staiger, PharmD, BCPS directly ›
How we checked

Why No Interaction Is Listed for Docusate

Interactions in our licensed database are recorded against drug classes, not just single drug names. Docusate is filed under a single classification — oral drugs. Strawberry has documented interactions with 2 drug classes — the most serious being anticoagulant/antiplatelet drugs (moderate) and p-glycoprotein substrates (moderate) — and none of Docusate’s classifications are among them.

Classification data comes from our licensed Natural Medicines dataset. A medication can belong to classes beyond those recorded there, so this describes how the check was run — it is not a safety guarantee.

Keep it in perspective

Strawberry Does Interact With Other Medications

Strawberry has 316 moderate known drug interactions in our database — Docusate isn’t one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Strawberry

Covers the 2,830 medications we’ve checked against Strawberry. Pick one to open its full report.

What to actually watch for

What Strawberry Itself Has Been Linked To

This is not an interaction — nothing below involves Docusate. It is the side-effect record for Strawberry on its own, from the licensed Natural Medicines monograph. If something new turns up after you add Strawberry, this list is the first place to look. 2 entries are worth acting on rather than waiting out — marked below.

  • Hives Worth acting on Additional detail

    “Orally, consuming strawberry has been reported to cause allergic reactions, including oral allergy syndrome and skin reactions, in some patients.. Topically, strawberry has caused contact urticaria in one case report. Overall, allergy to strawberry appears to be rare.”

    Strawberry · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    2 sources cited
    1. 103880. Cabrera-Freitag P, Bermejo Becerro A, Abreu Ramírez MG, et al. Allergy to strawberry in children from the Mediterranean area: is it really allergy? J Investig Allergol Clin Immunol 2020;30(4):283-5. PubMed
    2. 13637. Grattan CE, Harman RR. Contact urticaria to strawberry. Contact Dermatitis 1985;13:191-2. . PubMed
  • An allergic reaction Worth acting on Additional detail

    “Orally, strawberry is well tolerated when taken in the amounts commonly found in food. When taken in medicinal amounts, strawberry seems to be generally well tolerated. Rarely, strawberry has been reported to cause nausea and allergic reactions, including oral allergy syndrome and skin reactions.

    Topically, strawberry can cause contact dermatitis.”

    Strawberry · Natural Medicines adverse-effect record, reported in allergic rhinitis (hay fever).

    6 sources cited
    1. 100109. Basu A, Betts NM, Nguyen A, Newman ED, Fu D, Lyons TJ. Freeze-dried strawberries lower serum cholesterol and lipid peroxidation in adults with abdominal adiposity and elevated serum lipids. J Nutr. 2014;144(6):830-7. PubMed
    2. 100113. Moazen S, Amani R, Homayouni Rad A, Shahbazian H, Ahmadi K, Taha Jalali M. Effects of freeze-dried strawberry supplementation on metabolic biomarkers of atherosclerosis in subjects with type 2 diabetes: a randomized double-blind controlled trial. Ann Nutr PubMed
    3. 100116. Schell J, Scofield RH, Barrett JR, et al. Strawberries improve pain and inflammation in obese adults with radiographic evidence of knee osteoarthritis. Nutrients. 2017;9(9):949. PubMed
    4. 100119. Amani R, Moazen S, Shahbazian H, Ahmadi K, Jalali MT. Flavonoid-rich beverage effects on lipid profile and blood pressure in diabetic patients. World J Diabetes. 2014;5(6):962-8. PubMed
    5. 103880. Cabrera-Freitag P, Bermejo Becerro A, Abreu Ramírez MG, et al. Allergy to strawberry in children from the Mediterranean area: is it really allergy? J Investig Allergol Clin Immunol 2020;30(4):283-5. PubMed
    6. 13637. Grattan CE, Harman RR. Contact urticaria to strawberry. Contact Dermatitis 1985;13:191-2. . PubMed
  • A skin rash Additional detail

    Recorded for Strawberry in the same Natural Medicines adverse-effect record shown under An allergic reaction above.

  • Nausea Additional detail

    “Orally, taking freeze-dried strawberry powder 50 grams daily has been reported to cause nausea in clinical trials.”

    Strawberry · Natural Medicines adverse-effect record, reported in nausea and vomiting.

    2 sources cited
    1. 100113. Moazen S, Amani R, Homayouni Rad A, Shahbazian H, Ahmadi K, Taha Jalali M. Effects of freeze-dried strawberry supplementation on metabolic biomarkers of atherosclerosis in subjects with type 2 diabetes: a randomized double-blind controlled trial. Ann Nutr PubMed
    2. 100119. Amani R, Moazen S, Shahbazian H, Ahmadi K, Jalali MT. Flavonoid-rich beverage effects on lipid profile and blood pressure in diabetic patients. World J Diabetes. 2014;5(6):962-8. PubMed

Everything above comes from the Natural Medicines adverse-effect record for Strawberry — expand a row for the licensed statement it rests on. We haven’t matched Docusate to its FDA label in our system yet, so we can’t compare its own side-effect list here — the leaflet that comes with your prescription is the authoritative list for Docusate.

Everything else you take

See Every Supplement That Interacts With Docusate

This page covers Strawberry only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Docusate page lists 17 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), Coffee Charcoal (moderate), European Mandrake (moderate), Glucomannan (moderate) and Guar Gum (moderate).

By severity: 1 major · 7 moderate · 9 minor.

Open the Docusate interaction page

One more smart check

Taking Strawberry as Part of a Dietary Supplement Product? Check It for Interactions

We hold 2,806 real supplement products containing Strawberry, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Strawberry. Even though Strawberry itself has no known interaction with Docusate, another ingredient on your label might. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Strawberry and Docusate Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Strawberry
Top 10%

#100 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Docusate
Top 5%

#34 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Where does our data come from?
  • Source: the Natural Medicines (TRC Healthcare) clinical database — the evidence-graded professional reference for herb & supplement interactions.
  • Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources. See every Strawberry reference on this page ↓
  • Freshness: we automatically re-check this combination every week — this pair was last verified September 13, 2026. The Strawberry and Docusate records this page draws on were last updated July 10, 2026.
  • What “no known interaction” means: no documented interaction in the sources above — not a guarantee of safety. Supplements are studied far less than prescription drugs, so we say exactly what the evidence supports, and nothing more.
Data structure & sourcing designed and verified by .
Supplement

About Strawberry

What is Strawberry?

  • General antioxidant support
  • Heart and blood vessel health
  • Blood sugar support
  • Skin and oral health
  • Source of vitamin C and fiber

Strawberry is a popular, nutrient-rich fruit that supplies vitamin C, fiber, and antioxidant plant compounds. Eating strawberries as part of a balanced diet is healthy for most people, but concentrated supplement forms have only limited research behind specific health claims. If you have allergies or take it as a supplement, check with your pharmacist or doctor.

Fragaria × ananassa · Rosaceae · Fruit (berries); leaves are also used in some traditional preparations · Fresh or frozen fruit, juice, powder, extracts, capsules, and leaf tea

An interaction check asks whether these two react with each other — it does not ask whether Strawberry is a good idea for someone in your situation. Here is what our Strawberry record says about it on its own.

Strawberry: dosing

There is no official or standardized dose of strawberry for any health condition. As a food, a typical serving is about a cup of fresh strawberries, which fits easily into a healthy diet.For supplements such as powders, extracts, or capsules, follow the directions on the product label, since concentrations vary widely between brands.

From our Strawberry monograph — the full record covers uses, side effects and every documented interaction.

Read the full Strawberry monograph & all interactions
Medication

About Stool Softeners

What Is Stool Softeners Used For?

Brand name: Colace

  • Stool softeners are used on a short-term basis to relieve constipation by people who should avoid straining during bowel movements because of heart conditions, hemorrhoids, and other problems. They work by softening stools to make them easier to pass.

See full Stool Softeners drug information
Keep checking

Other Drugs & Strawberry

Browse every other medication we’ve checked against Strawberry — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
316Moderate
0Minor
2,513No known interaction
Moderate

316 interactions

Showing 60 of 316 moderate interactions — see all 316 on the Strawberry page.

No interaction 2,513 drugs checked — show the list
Evidence & sources

Strawberry References

The 18 references that drive our Strawberry monograph and interaction data, from the evidence-graded Natural Medicines (TRC Healthcare) database. Citations with a link open the study on PubMed or the publisher’s site.

  1. Grattan CE, Harman RR. Contact urticaria to strawberry. Contact Dermatitis 1985;13:191-2. . PubMed
  2. Dutta-Roy, A. K., Crosbie, L., and Gordon, M. J. Effects of tomato extract on human platelet aggregation in vitro. Platelets. 2001;12(4):218-227. PubMed
  3. Van Gelder, J., Deferme, S., Naesens, L., De Clercq, E., van den, Mooter G., Kinget, R., and Augustijns, P. Intestinal absorption enhancement of the ester prodrug tenofovir disoproxil fumarate through modulation of the biochemical barrier by defined este
  4. Deferme, S., Van Gelder, J., and Augustijns, P. Inhibitory effect of fruit extracts on P-glycoprotein-related efflux carriers: an in-vitro screening. J Pharm Pharmacol 2002;54(9):1213-1219.
  5. Naemura, A., Mitani, T., Ijiri, Y., Tamura, Y., Yamashita, T., Okimura, M., and Yamamoto, J. Anti-thrombotic effect of strawberries. Blood Coagul.Fibrinolysis 2005;16(7):501-509. PubMed
  6. Basu A, Betts NM, Nguyen A, Newman ED, Fu D, Lyons TJ. Freeze-dried strawberries lower serum cholesterol and lipid peroxidation in adults with abdominal adiposity and elevated serum lipids. J Nutr. 2014;144(6):830-7. PubMed
  7. Feresin RG, Johnson SA, Pourafshar S, et al. Impact of daily strawberry consumption on blood pressure and arterial stiffness in pre- and stage 1-hypertensive postmenopausal women: a randomized controlled trial. Food Funct. 2017;8(11):4139-4149. PubMed
  8. Moazen S, Amani R, Homayouni Rad A, Shahbazian H, Ahmadi K, Taha Jalali M. Effects of freeze-dried strawberry supplementation on metabolic biomarkers of atherosclerosis in subjects with type 2 diabetes: a randomized double-blind controlled trial. Ann Nutr PubMed
  9. Schell J, Scofield RH, Barrett JR, et al. Strawberries improve pain and inflammation in obese adults with radiographic evidence of knee osteoarthritis. Nutrients. 2017;9(9):949. PubMed
  10. Zunino SJ, Parelman MA, Freytag TL, et al. Effects of dietary strawberry powder on blood lipids and inflammatory markers in obese human subjects. Br J Nutr. 2012;108(5):900-9. PubMed
  11. Amani R, Moazen S, Shahbazian H, Ahmadi K, Jalali MT. Flavonoid-rich beverage effects on lipid profile and blood pressure in diabetic patients. World J Diabetes. 2014;5(6):962-8. PubMed
  12. Cabrera-Freitag P, Bermejo Becerro A, Abreu Ramírez MG, et al. Allergy to strawberry in children from the Mediterranean area: is it really allergy? J Investig Allergol Clin Immunol 2020;30(4):283-5. PubMed
  13. Hadi A, Askarpour M, Miraghajani M, Symonds ME, Sheikhi A, Ghaedi E. Effects of strawberry supplementation on cardiovascular risk factors: a comprehensive systematic review and meta-analysis of randomized controlled trials. Food Funct 2019;10(11):6987-98. PubMed
  14. Gao Q, Qin LQ, Arafa A, Eshak ES, Dong JY. Effects of strawberry intervention on cardiovascular risk factors: a meta-analysis of randomised controlled trials. Br J Nutr 2020;124(3):241-6. PubMed
  15. Basu A, Izuora K, Hooyman A, Scofield HR, Ebersole JL. Dietary Strawberries Improve Serum Metabolites of Cardiometabolic Risks in Adults with Features of the Metabolic Syndrome in a Randomized Controlled Crossover Trial. Int J Mol Sci 2023;24(3):2051. PubMed

Medication overviews come from MedlinePlus (NIH); supplement label data from the NIH Dietary Supplement Label Database. Content is written and reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

Pharmacist Counseling Corner

Taking Strawberry and Docusate Together: Common Questions

Is it safe to take Strawberry with Docusate?
We do not list a known interaction between Strawberry and Docusate. That does not guarantee the combination is risk-free, so confirm with your pharmacist or doctor — especially if you take other medications or have a health condition.
How was the Strawberry and Docusate combination checked?
Interactions in our licensed database are recorded against drug classes. Docusate is filed under 1 classification, and Strawberry has documented interactions with 2 drug classes — none of Docusate's classifications are among them. A medication can belong to classes beyond those recorded in our dataset, so this describes how the check was run rather than guaranteeing safety.
Does Strawberry interact with any other medications?
Yes. Strawberry has 316 documented drug interactions in our database — Docusate is simply not one of them. If you take anything else, it is worth checking each one; they are all listed on this page.
Does Docusate interact with any supplements?
Yes. Docusate has documented interactions with 17 supplements in our database — Strawberry is not one of them. The Docusate interaction page linked on this page lists every one, ranked by severity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Docusate and Strawberry?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.