Drug & supplement interaction

Wild Carrot + Irbesartan

Irbesartan brand names: Avapro, Aprovel.

Moderate Interaction
The bottom line Moderate

Wild Carrot has a moderate interaction with Irbesartan. Theoretically, excessive doses of wild carrot seed oil might interfere with antihypertensive therapy due to cardiotonic effects.

Read the full interaction report
SeverityModerate
LikelihoodProbable
EvidenceD
What do Severity, Likelihood & Evidence mean?
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Interaction report

Wild Carrot and Irbesartan

Here is the interaction we found between these two, with the evidence behind it.

Moderate

ANTIHYPERTENSIVE DRUGS

Why this applies to Irbesartan

Irbesartan falls under ANTIHYPERTENSIVE DRUGS — the group Wild Carrot interacts with.

Theoretically, excessive doses of wild carrot seed oil might interfere with antihypertensive therapy due to cardiotonic effects.
Severity Moderate Likelihood Probable Evidence D

Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports..

Dr. Brian Staiger, PharmD, BCPS
Dr. Brian Staiger explains PharmD, Clinical Pharmacist

Here's the gist for irbesartan, your blood pressure pill: in concentrated doses, wild carrot seed oil is thought to have cardiotonic activity that may tug on blood pressure in the wrong direction. The worry is that it could work against irbesartan and keep your numbers from staying as low as you and your doctor want.

I'll be honest with you, this concern is theoretical, based on how the plant behaves in the lab rather than real patient studies. A normal serving of garden carrots won't do anything. But strong, concentrated seed oil supplements are a different story. If you're tempted to try wild carrot, check in with your pharmacist first and keep an eye on your home blood pressure readings.

References
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.

What These Ratings Mean

Every interaction above is graded three ways — here’s the key to each label.

Severity how clinically significant the interaction is
Major

Clinically significant. Avoid the combination, or use only under close professional supervision.

Moderate

Usually worth avoiding or managing — may need monitoring, a dose change, or timing apart.

Minor

Generally not serious. Be aware of it and mention it to your pharmacist.

Likelihood how strong the evidence is that the interaction actually happens in people
  • LikelyWell-controlled human studies have demonstrated the likely existence of this interaction.
  • ProbableInteraction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • PossibleInteraction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists.
  • UnlikelyInteraction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Evidence the quality of the studies behind the rating (graded A–D)
  • AHigh-quality meta-analysis (quantitative systematic review).
  • BCase-control study.
  • CConsensus.
  • DAnecdotal evidence.

These ratings are for information only. Never start, stop, or otherwise change your therapy before speaking with your provider.

Keep it in perspective

Wild Carrot Also Interacts With Other Medications

Wild Carrot has 474 moderate known drug interactions in our database — the Irbesartan one above is one of them. If you take anything else, check it against the full list below.

Taking anything else?

Check Another of Your Medications Against Wild Carrot

Covers the 2,830 medications we’ve checked against Wild Carrot. Pick one to open its full report.

From our Q&A

Questions About Wild Carrot or Irbesartan

These are real questions from readers, answered by the pharmacists at HelloPharmacist — written by a person, not generated from a database. Each one covers Wild Carrot or Irbesartan, not necessarily both, but if one is close to what you were about to ask it will usually go further than a database entry can:

Not quite your question? Ask our pharmacists directly — it is free, there is no account required, and answers usually come back within 24 hours.

Everything else you take

See Every Supplement That Interacts With Irbesartan

This page covers Wild Carrot only. If you take other supplements — a multivitamin, a sleep aid, something for joints — the Irbesartan page lists 182 supplements it has a documented interaction with, worst first, each one explained.

The most serious there right now: Activated Charcoal (major), American Hellebore (major), American Mistletoe (major), Tyramine (major) and Adrafinil (moderate).

By severity: 4 major · 145 moderate · 33 minor.

Open the Irbesartan interaction page

One more smart check

Taking Wild Carrot as Part of a Dietary Supplement Product? Check It for Interactions

We hold 7 real supplement products containing Wild Carrot, each one broken down to its full ingredient list — and combination products often carry several ingredients besides Wild Carrot. Your product may carry other ingredients that interact with Irbesartan too, on top of Wild Carrot — and those would not show on this page. Find your product and we’ll check every ingredient on its label:

How much people look this up

Where Wild Carrot and Irbesartan Sit Against Everything Else

Out of every supplement and medication people look up on HelloPharmacist, here is where these two land this week — and which way each has been moving.

Supplement Wild Carrot
Steady interest

#1,108 of 1,452 supplements looked up here in the last 7 days

29 days ago today
Medication Irbesartan
Top half

#1,325 of 2,830 medications looked up here in the last 7 days

29 days ago today

Position among everything looked up on this site, not a measure of how commonly either one is used or how important it is. A supplement can climb this list because of a news story. It counts every request to the page, automated ones included, and nothing here identifies anyone.

Supplement

About Wild Carrot

What is Wild Carrot?

Wild Carrot
  • Urinary and bladder complaints
  • Digestive upset and gas
  • Menstrual support
  • Supporting milk production
  • Mild diuretic (water pill) effect

Wild carrot is a traditional herb (the wild ancestor of the garden carrot) used mostly for urinary, digestive, and menstrual complaints. High-quality human studies are lacking, so its benefits are unproven, and it should be avoided in pregnancy because of traditional use to affect the uterus. Talk with your pharmacist or doctor before using it.

Read the full Wild Carrot monograph & all interactions
Medication

About Irbesartan

What Is Irbesartan Used For?

Brand names: Avapro, Aprovel

Irbesartan tablets — sold as Avapro and under the generic name Irbesartan — are used to treat high blood pressure (hypertension). Lowering blood pressure reduces the risk of serious cardiovascular events, including stroke and heart attack. The medication can be used alone or combined with other blood pressure medicines.

Irbesartan tablets are also used to treat diabetic nephropathy (kidney disease caused by diabetes) in adults who have type 2 diabetes, high blood pressure, elevated creatinine levels, and significant protein in the urine. In these patients, it slows the worsening of kidney disease.

See full Irbesartan drug information
Keep checking

Other Drugs & Wild Carrot

Browse every other medication we’ve checked against Wild Carrot — both the ones with a known interaction and the ones without. Select any drug for the full detail.

0Major
474Moderate
0Minor
2,355No known interaction
Moderate

474 interactions

Showing 60 of 474 moderate interactions — see all 474 on the Wild Carrot page.

No interaction 2,355 drugs checked — show the list
Sources

Sources & How We Checked

Interaction details are evidence-graded and sourced from the Natural Medicines database. The medication overview comes from MedlinePlus.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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Pharmacist Counseling Corner

Taking Wild Carrot and Irbesartan Together: Common Questions

Can you take Wild Carrot with Irbesartan?
There is a moderate interaction, so it may be acceptable with monitoring or timing changes — but check with your pharmacist first. Read the full details on this page and confirm with your pharmacist before combining them.
How serious is the Wild Carrot and Irbesartan interaction?
We rate it Moderate. This combination may require monitoring, a dose adjustment, or separating the times you take each one. Consult your pharmacist before using them together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Still Have a Question About Irbesartan and Wild Carrot?

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This information is for education only and is not a substitute for professional medical advice. Always check with your pharmacist or doctor before starting, stopping, or combining supplements and medications.