What Supplements Interact with Adenosine?
Adenosine brand name: ATP Tablets. Every interaction below applies to the brands too.
Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy
What is this page for?
One answer, for one medication: what supplements and herbal products interact with Adenosine? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.
This page covers supplement interactions only — to check Adenosine against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy
What is this?
The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.Adenosine is usually given in a hospital, to reset a racing heart rhythm or to widen the heart's vessels for a cardiac stress test, and the 29 supplement interactions on file earn genuine vigilance. The dominant theme is caffeine: twelve entries, covering coffee, teas, and caffeinated herbs, could blunt adenosine's vessel-widening effect and muddy stress-test results. The single major-rated interaction is activated charcoal, which can soak up medicines in the gut and cut how much reaches the body.
Most of the remaining entries are fibers, gums, and mucilage-rich herbs such as glucomannan that slow or reduce absorption of medicines taken by mouth, which matters for the oral ATP tablet form. Nineteen sit at moderate and nine at minor, but the charcoal entry deserves your first read. Skip caffeine on stress-test day unless your care team clears it, and keep fiber supplements spaced well apart from any oral dose.
This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓
Adenosine: Top Interactions at a Glance
The most significant Adenosine supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.
Showing the 12 highest-ranked of 29 interacting ingredients — plus 1,423 more checked with no known interaction. See the complete ranked list.
The Major Interactions to Know About
The most clinically significant Adenosine + supplement combinations in our database, best-documented first. Open any card for the full report.
Every Supplement Checked Against Adenosine
All 1,452 ingredients in our database, ranked by severity — 29 with a Adenosine interaction on file and 1,423 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.
Looking for an interaction with a specific supplement product? Search products instead ↓
No ingredients match “”.
Activated CharcoalActivated Carbon, animal Charcoal, carbo Vegetabilis, +13 more Probable
What it is: Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some...
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Adenosine interactionCoffee CharcoalCafé Arabica, café Carbonisé, café Robusta, +5 more Probable
What it is: Coffee charcoal is made by roasting green coffee beans until they turn black, creating a charcoal-like material used traditionally for diarr...
Coffee charcoal can reduce the absorption of orally administered drugs and should be separated from oral drug administration by at least two hours.
Read the full Coffee Charcoal + Adenosine interactionEuropean MandrakeMandragora Officinarum, alraunwurzel, mandragora, +7 more Probable
What it is: European mandrake is a highly toxic plant from the nightshade family that was used in ancient and medieval times as a sedative and pain reli...
Theoretically, concurrent use might increase absorption of some drugs because of inhibited gastrointestinal (GI) motility caused by European mandrake.
Read the full European Mandrake + Adenosine interactionGlucomannanGlucomanano, glucomannane, konjac, +1 more Probable
What it is: Glucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipati...
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Adenosine interactionBlack Tea Possible
What it is: Black tea is a popular caffeinated drink made from the fully oxidized leaves of the Camellia sinensis plant, and it contains caffeine and an...
Theoretically, black tea might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Read the full Black Tea + Adenosine interactionCaffeine Possible
What it is: Caffeine is a natural stimulant found in coffee, tea, and many other plants and products.
Theoretically, caffeine might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Read the full Caffeine + Adenosine interactionCocoaTheobroma Cacao, chocolat, chocolat Noir, +14 more Possible
What it is: Cocoa is rich in plant compounds called flavanols that may modestly support blood vessel function and blood pressure, but most chocolate pro...
Theoretically, cocoa might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Read the full Cocoa + Adenosine interactionCoffee Possible
What it is: Coffee is a widely consumed beverage made from roasted coffee beans, valued mainly for its caffeine, which boosts alertness and energy.
Theoretically, coffee might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Read the full Coffee + Adenosine interactionCola NutCola Acuminata, bissey Nut, bissy Nut, +10 more Possible
What it is: Cola nut is a caffeine-containing seed from West Africa used mainly as a natural stimulant for energy and alertness.
Theoretically, cola nut might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Read the full Cola Nut + Adenosine interactionGreen CoffeeCoffea Arabica, coffea Canephora, coffea Bukobensis, +2 more Possible
What it is: Green coffee is the unroasted bean of the coffee plant, prized for its high chlorogenic acid content.
Theoretically, green coffee might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Read the full Green Coffee + Adenosine interactionGreen TeaCamellia Sinensis, green Sencha Tea, green Tea Extract, +17 more Possible
What it is: Green tea is a popular beverage rich in antioxidants called catechins, and drinking it in normal amounts is considered safe for most people.
Theoretically, green tea might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Read the full Green Tea + Adenosine interactionGuar GumDietary Fiber, farine De Guar, fibre Alimentaire, +10 more Possible
What it is: Guar gum is a soluble, gel-forming fiber from the guar bean that may modestly help with cholesterol, blood sugar, and bowel regularity.
Guar gum might reduce the absorption of some oral drugs, potentially decreasing their effectiveness.
Read the full Guar Gum + Adenosine interactionGuaranaPaullinia Cupana, brazilian Cocoa, cacao Brésilien, +3 more Possible
What it is: Guarana is an Amazonian seed that is naturally high in caffeine, which explains most of its stimulant and energy effects.
Theoretically, guarana might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Read the full Guarana + Adenosine interactionGum ArabicAcacia, acacia Gum, arabic Gum, +16 more Possible
What it is: Gum arabic is a soluble dietary fiber from the acacia tree that is widely used as a safe food additive and is sometimes taken as a supplemen...
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Gum Arabic + Adenosine interactionIlex Guayusa Possible
What it is: Ilex guayusa is a caffeine-containing holly leaf from the Amazon, traditionally brewed as a tea for energy and alertness, much like yerba ma...
Theoretically, Ilex guayusa might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Read the full Ilex Guayusa + Adenosine interactionOolong Tea Possible
What it is: Oolong tea is a traditional partially oxidized tea made from the same plant as green and black tea, and it provides caffeine and plant antio...
Theoretically, oolong tea might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Read the full Oolong Tea + Adenosine interactionPu-erh Tea Possible
What it is: Pu-erh tea is a fermented, aged form of tea made from the same plant as green and black tea.
Theoretically, pu-erh tea might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Read the full Pu-erh Tea + Adenosine interactionSlippery ElmIndian Elm, moose Elm, olmo Americano, +7 more Possible
What it is: Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and ir...
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Adenosine interactionTragacanthAdragante, astragale Adragant, astragale De Marseille, +14 more Possible
What it is: Tragacanth is a plant gum used mainly as a thickener and emulsifier in foods, cosmetics, and medicines, and traditionally to soothe the thro...
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Tragacanth + Adenosine interactionYerba MateIlex Paraguariensis, chimarrao, green Mate, +14 more Possible
What it is: Yerba mate is a caffeine-containing herbal beverage from South America that is widely enjoyed for its stimulating, coffee-like effects.
Theoretically, the caffeine in yerba mate might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Read the full Yerba Mate + Adenosine interactionThyroid Extract Likely
What it is: Thyroid extract supplements are made from dried animal thyroid gland and may contain real thyroid hormones (T3 and T4), but the amounts in o...
Food and medications can interfere with thyroid hormone absorption.
Read the full Thyroid Extract + Adenosine interactionAgarAgar-agar, agarose, agarose Gel, +17 more Possible
What it is: Agar is a plant-based gel made from red seaweed that is widely used as a vegetarian alternative to gelatin and as a source of dietary fiber.
Agar forms a thick gel, which may disrupt the absorption of nutrients and medications.
Read the full Agar + Adenosine interactionAlginAlginate, alginate De Calcium, alginate De Magnésium, +12 more Possible
What it is: Algin (alginate) is a fiber-like substance from brown seaweed that is widely used as a thickener, gel, and binder in foods and medicines.
Theoretically, algin can alter the absorption of oral drugs.
Read the full Algin + Adenosine interactionBlack PsylliumAfrican Plantain, brown Psyllium, dietary Fiber, +16 more Possible
What it is: Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive...
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Black Psyllium + Adenosine interactionBlond PsylliumPlantago Ovata, balle De Psyllium, blond Plantago, +14 more Possible
What it is: Blond psyllium is a soluble fiber from the seed husks of Plantago ovata, and it is one of the better-studied fiber supplements.
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Blond Psyllium + Adenosine interactionCarobCeratonia Siliqua, algarrobo, carob Flour, +16 more Possible
What it is: Carob is a Mediterranean tree whose pods are widely used as a caffeine-free, naturally sweet cocoa alternative and as a thickener (carob gum...
Theoretically, carob might also impair the absorption of oral drugs.
Read the full Carob + Adenosine interactionKaraya GumBassora Tragacanth, goma Karaya, gomme Karaya, +14 more Possible
What it is: Karaya gum is a natural plant gum from the Sterculia tree that is mostly used as a bulk-forming laxative and as a thickener or adhesive in f...
Co-administration of oral drugs with bulk forming laxatives such as karaya gum may decrease, increase, or have no effect on the absorption of drugs.
Read the full Karaya Gum + Adenosine interactionMarshmallowAlthaea Officinalis, altea, alteia, +16 more Possible
What it is: Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sor...
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow + Adenosine interactionXanthan GumBacterial Polysaccharide, corn Sugar Gum, goma Xantana, +7 more Possible
What it is: Xanthan gum is a fermentation-made fiber widely used to thicken and stabilize foods and to thicken liquids for people with swallowing diffic...
Theoretically, xanthan gum can alter the absorption of oral drugs due to its fiber qualities.
Read the full Xanthan Gum + Adenosine interactionCan You Take It With Adenosine?
One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.
Can you take Caffeine with Adenosine?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, caffeine might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Full Caffeine + Adenosine answerCan you take Karaya Gum with Adenosine?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Co-administration of oral drugs with bulk forming laxatives such as karaya gum may decrease, increase, or have no effect on the absorption o...
Full Karaya Gum + Adenosine answerCan you take Green Tea with Adenosine?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, green tea might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Full Green Tea + Adenosine answerCan you take Guar Gum with Adenosine?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Guar gum might reduce the absorption of some oral drugs, potentially decreasing their effectiveness.
Full Guar Gum + Adenosine answerCan you take Guarana with Adenosine?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, guarana might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Full Guarana + Adenosine answerCan you take Gum Arabic with Adenosine?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Full Gum Arabic + Adenosine answerCan you take Ilex Guayusa with Adenosine?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Ilex guayusa might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Full Ilex Guayusa + Adenosine answerCan you take Oolong Tea with Adenosine?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, oolong tea might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Full Oolong Tea + Adenosine answerCan you take Pu-erh Tea with Adenosine?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, pu-erh tea might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress testing.
Full Pu-erh Tea + Adenosine answerCan you take Slippery Elm with Adenosine?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Full Slippery Elm + Adenosine answerCan you take Tragacanth with Adenosine?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tragacanth might alter absorption of oral drugs.
Full Tragacanth + Adenosine answerCan you take Yerba Mate with Adenosine?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, the caffeine in yerba mate might decrease the vasodilatory effects of adenosine and interfere with its use prior to stress te...
Full Yerba Mate + Adenosine answerCan you take Thyroid Extract with Adenosine?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Food and medications can interfere with thyroid hormone absorption.
Full Thyroid Extract + Adenosine answerCan you take Agar with Adenosine?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Agar forms a thick gel, which may disrupt the absorption of nutrients and medications.
Full Agar + Adenosine answerCan you take Algin with Adenosine?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, algin can alter the absorption of oral drugs.
Full Algin + Adenosine answerCan you take Black Psyllium with Adenosine?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Full Black Psyllium + Adenosine answerCan you take Blond Psyllium with Adenosine?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Full Blond Psyllium + Adenosine answerCan you take Carob with Adenosine?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, carob might also impair the absorption of oral drugs.
Full Carob + Adenosine answerCan you take Marshmallow with Adenosine?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Full Marshmallow + Adenosine answerCan you take Xanthan Gum with Adenosine?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, xanthan gum can alter the absorption of oral drugs due to its fiber qualities.
Full Xanthan Gum + Adenosine answerWhat Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
How Does Our Interaction Checker Work?
Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).
So the check works in three steps: (1) Adenosine is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Adenosine, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.
Adenosine sits in 2 interaction categories. Open any one to see what the group means:
Oral Drugs 17 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
17 of the supplement ingredients on this page reach Adenosine through this category.
Adenosine (Adenocard) 12 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
12 of the supplement ingredients on this page reach Adenosine through this category.
Take a Supplement Product? Check the Whole Bottle Against Adenosine
Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Adenosine.
Search a supplement product
Type a product name, brand, or UPC — smart search across our full catalog.
Grounded search over our product catalog — every verdict comes from our interaction database, never AI guesswork. How we use AI
Or scan the bottle
Photograph any Supplement Facts panel — we read the ingredients and check each one against your medications. Free, in seconds.
Prefer typing? The interaction checker looks up products by name too.
Products that contain Adenosine-interacting ingredients
Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Adenosine.
Adenosine & Supplements: Common Questions
What supplements interact with Adenosine?
Which Adenosine supplement interactions are the most serious?
Can I take vitamins or supplements while on Adenosine?
Do brands like ATP Tablets have the same supplement interactions as Adenosine?
Where do these interaction ratings come from?
What about Adenosine and my other medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
More Free Pharmacist Tools
Where This Data Comes From — and Why You Can Trust It
🧪 Licensed clinical database
Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.
🧑⚕️ Pharmacist review
This page is curated and coded by Dr. Brian Staiger, PharmD, BCPS, Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.
🔄 Kept current
Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 24, 2026.
🔍 Full transparency
How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.
Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.