What Supplements Interact with Artemether?
Artemether brand names: Artenam, Paluther. Every interaction below applies to the brands too.
Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy
What is this page for?
One answer, for one medication: what supplements and herbal products interact with Artemether? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.
This page covers supplement interactions only — to check Artemether against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy
What is this?
The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.Artemether (Artenam, Paluther) treats malaria, an illness where every dose needs to work, and I would handle its 30 documented supplement interactions with genuine care, the seven major-rated ones above all. They pull in two directions. Some change how much artemether the body actually absorbs: grapefruit juice can raise its blood levels by 90% to 250%, while activated charcoal and several fiber products can drag them down. Thirteen others share artemether's tendency to stretch the QT interval, the heart's electrical reset time, which raises the odds of a dangerous rhythm.
Undertreated malaria is its own emergency, so lower absorption is not a small problem here. Space any fiber or charcoal product well apart from each dose, and let your pharmacist see the full supplement list before treatment starts. The remaining entries split into 14 moderate and 9 minor, but the seven majors are where to focus first.
This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓
Artemether: Top Interactions at a Glance
The most significant Artemether supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.
Showing the 12 highest-ranked of 30 interacting ingredients — plus 1,422 more checked with no known interaction. See the complete ranked list.
The Major Interactions to Know About
The most clinically significant Artemether + supplement combinations in our database, best-documented first. Open any card for the full report.
Grapefruit juice can increase blood levels of oral artemether, potentially increasing the effects and adverse effects of artemether.
Read the full interaction Major Likelihood Probable Activated Charcoal + ArtemetheriActivated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full interaction Major Likelihood Probable Arsenic + ArtemetheriArsenic trioxide can prolong the QT interval.
Read the full interaction Major Likelihood Probable Cesium + ArtemetheriTheoretically, taking cesium concomitantly with other drugs that prolong the QT interval may increase the risk of ventricular arrhythmias and death.
Read the full interaction Major Likelihood Probable Ephedra + ArtemetheriTheoretically, ephedra might have an additive effect with drugs that prolong the QT interval.
Read the full interaction Major Likelihood Probable Sida Cordifolia + ArtemetheriTheoretically, Sida cordifolia might increase the risk of additive QT interval prolongation when taken with QT interval-prolonging drugs.
Read the full interactionEvery Supplement Checked Against Artemether
All 1,452 ingredients in our database, ranked by severity — 30 with a Artemether interaction on file and 1,422 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.
Looking for an interaction with a specific supplement product? Search products instead ↓
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GrapefruitCitrus Paradisi Likely
What it is: Grapefruit is a nutritious citrus fruit rich in vitamin C and other nutrients, and it is generally safe to eat.
Grapefruit juice can increase blood levels of oral artemether, potentially increasing the effects and adverse effects of artemether.
Read the full Grapefruit + Artemether interactionActivated CharcoalActivated Carbon, animal Charcoal, carbo Vegetabilis, +13 more Probable
What it is: Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some...
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Artemether interactionArsenic Probable
What it is: Arsenic is a naturally occurring element that is toxic in its inorganic form, and it is not a supplement you should take to improve your hea...
Arsenic trioxide can prolong the QT interval.
Read the full Arsenic + Artemether interactionCesium Probable
What it is: Cesium chloride is a mineral salt sold as an alternative cancer therapy ('high pH therapy'), but there is no reliable scientific evidence th...
Theoretically, taking cesium concomitantly with other drugs that prolong the QT interval may increase the risk of ventricular arrhythmias and death.
Read the full Cesium + Artemether interactionEphedraEphedra Distachya, belcho, cao Mahuang, +13 more Probable
What it is: Ephedra (ma huang) contains powerful stimulants like ephedrine that affect the heart and nervous system.
Theoretically, ephedra might have an additive effect with drugs that prolong the QT interval.
Read the full Ephedra + Artemether interactionSida CordifoliaAbutilon En Épi, bala, bariar, +15 more Probable
What it is: Sida cordifolia (bala or country mallow) is a traditional Ayurvedic plant that naturally contains ephedrine, a powerful stimulant.
Theoretically, Sida cordifolia might increase the risk of additive QT interval prolongation when taken with QT interval-prolonging drugs.
Read the full Sida Cordifolia + Artemether interactionAmerican HelleboreVeratrum Viride, american Veratrum, american White Hellebore, +11 more Possible
What it is: American Hellebore (Veratrum viride) is a highly poisonous plant whose root contains toxic alkaloids that can cause dangerous drops in heart...
American hellebore, also known as Veratrum viride, contains alkaloids that can potentially prolong the QT interval on an electrocardiogram (ECG).
Read the full American Hellebore + Artemether interactionCoffee CharcoalCafé Arabica, café Carbonisé, café Robusta, +5 more Probable
What it is: Coffee charcoal is made by roasting green coffee beans until they turn black, creating a charcoal-like material used traditionally for diarr...
Coffee charcoal can reduce the absorption of orally administered drugs and should be separated from oral drug administration by at least two hours.
Read the full Coffee Charcoal + Artemether interactionEuropean MandrakeMandragora Officinarum, alraunwurzel, mandragora, +7 more Probable
What it is: European mandrake is a highly toxic plant from the nightshade family that was used in ancient and medieval times as a sedative and pain reli...
Theoretically, concurrent use might increase absorption of some drugs because of inhibited gastrointestinal (GI) motility caused by European mandrake.
Read the full European Mandrake + Artemether interactionGlucomannanGlucomanano, glucomannane, konjac, +1 more Probable
What it is: Glucomannan is a soluble fiber from the konjac root that swells into a gel in your stomach, which may help with mild weight loss, constipati...
Theoretically, glucomannan may decrease absorption of drugs taken orally.
Read the full Glucomannan + Artemether interactionBitter OrangeCitrus Aurantium, aurantii Fructus, aurantium, +17 more Possible
What it is: Bitter orange is a citrus fruit whose extracts contain synephrine, a mild stimulant often added to weight-loss and energy supplements.
Theoretically, bitter orange might have an additive effect when combined with drugs that prolong the QT interval, potentially increasing the risk of ventricular arrhythmias.
Read the full Bitter Orange + Artemether interactionCinchonaCinchona Calisaya, arbol De La Quina, bois Aux Fièvres, +14 more Possible
What it is: Cinchona bark is the natural source of quinine and has been used for centuries to treat malaria and fever, but the bark itself is not standa...
Theoretically, taking cinchona with other QT interval-prolonging drugs might cause an additive effect and increase the risk of ventricular arrhythmias.
Read the full Cinchona + Artemether interactionEvodia Possible
What it is: Evodia is a fruit used in traditional Chinese medicine, most often for digestive complaints, headaches, and menstrual pain.
Theoretically, evodia might have an additive effect with drugs that prolong the QT interval, potentially increasing the risk of ventricular arrhythmias.
Read the full Evodia + Artemether interactionGuar GumDietary Fiber, farine De Guar, fibre Alimentaire, +10 more Possible
What it is: Guar gum is a soluble, gel-forming fiber from the guar bean that may modestly help with cholesterol, blood sugar, and bowel regularity.
Guar gum might reduce the absorption of some oral drugs, potentially decreasing their effectiveness.
Read the full Guar Gum + Artemether interactionGum ArabicAcacia, acacia Gum, arabic Gum, +16 more Possible
What it is: Gum arabic is a soluble dietary fiber from the acacia tree that is widely used as a safe food additive and is sometimes taken as a supplemen...
Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.
Read the full Gum Arabic + Artemether interactionIbogaTabernanthe Iboga, bois Sacré, eboka Possible
What it is: Iboga is a Central African shrub whose root bark contains ibogaine, a powerful hallucinogenic compound studied mainly for addiction.
Theoretically, iboga may have an additive effect with drugs that prolong the QT interval.
Read the full Iboga + Artemether interactionK2/spice Possible
What it is: K2/Spice is NOT a herbal supplement — it is plant material sprayed with man-made synthetic cannabinoid chemicals.
Theoretically, K2/spice might have an additive effect with drugs that prolong the QT interval and increase the risk of ventricular arrhythmias.
Read the full K2/spice + Artemether interactionPanax GinsengAsian Ginseng, asiatic Ginseng, chinese Ginseng, +12 more Possible
What it is: Panax ginseng is a popular traditional herb used to boost energy, ease stress, and support overall wellness, though scientific evidence is m...
Theoretically, Panax ginseng has an additive effect with drugs that prolong the QT interval and potentially increase the risk of ventricular arrhythmias.
Read the full Panax Ginseng + Artemether interactionPuravive Possible
What it is: Puravive is a branded, multi-ingredient capsule marketed mainly for weight loss by claiming to boost brown fat activity, but there is no pub...
Puravive contains Panax ginseng.
Read the full Puravive + Artemether interactionSlippery ElmIndian Elm, moose Elm, olmo Americano, +7 more Possible
What it is: Slippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and ir...
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm + Artemether interactionTragacanthAdragante, astragale Adragant, astragale De Marseille, +14 more Possible
What it is: Tragacanth is a plant gum used mainly as a thickener and emulsifier in foods, cosmetics, and medicines, and traditionally to soothe the thro...
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Tragacanth + Artemether interactionThyroid Extract Likely
What it is: Thyroid extract supplements are made from dried animal thyroid gland and may contain real thyroid hormones (T3 and T4), but the amounts in o...
Food and medications can interfere with thyroid hormone absorption.
Read the full Thyroid Extract + Artemether interactionAgarAgar-agar, agarose, agarose Gel, +17 more Possible
What it is: Agar is a plant-based gel made from red seaweed that is widely used as a vegetarian alternative to gelatin and as a source of dietary fiber.
Agar forms a thick gel, which may disrupt the absorption of nutrients and medications.
Read the full Agar + Artemether interactionAlginAlginate, alginate De Calcium, alginate De Magnésium, +12 more Possible
What it is: Algin (alginate) is a fiber-like substance from brown seaweed that is widely used as a thickener, gel, and binder in foods and medicines.
Theoretically, algin can alter the absorption of oral drugs.
Read the full Algin + Artemether interactionBlack PsylliumAfrican Plantain, brown Psyllium, dietary Fiber, +16 more Possible
What it is: Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive...
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Black Psyllium + Artemether interactionBlond PsylliumPlantago Ovata, balle De Psyllium, blond Plantago, +14 more Possible
What it is: Blond psyllium is a soluble fiber from the seed husks of Plantago ovata, and it is one of the better-studied fiber supplements.
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Blond Psyllium + Artemether interactionCarobCeratonia Siliqua, algarrobo, carob Flour, +16 more Possible
What it is: Carob is a Mediterranean tree whose pods are widely used as a caffeine-free, naturally sweet cocoa alternative and as a thickener (carob gum...
Theoretically, carob might also impair the absorption of oral drugs.
Read the full Carob + Artemether interactionKaraya GumBassora Tragacanth, goma Karaya, gomme Karaya, +14 more Possible
What it is: Karaya gum is a natural plant gum from the Sterculia tree that is mostly used as a bulk-forming laxative and as a thickener or adhesive in f...
Co-administration of oral drugs with bulk forming laxatives such as karaya gum may decrease, increase, or have no effect on the absorption of drugs.
Read the full Karaya Gum + Artemether interactionMarshmallowAlthaea Officinalis, altea, alteia, +16 more Possible
What it is: Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sor...
Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Read the full Marshmallow + Artemether interactionXanthan GumBacterial Polysaccharide, corn Sugar Gum, goma Xantana, +7 more Possible
What it is: Xanthan gum is a fermentation-made fiber widely used to thicken and stabilize foods and to thicken liquids for people with swallowing diffic...
Theoretically, xanthan gum can alter the absorption of oral drugs due to its fiber qualities.
Read the full Xanthan Gum + Artemether interactionCan You Take It With Artemether?
One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.
Can you take Glucomannan with Artemether?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, glucomannan may decrease absorption of drugs taken orally.
Full Glucomannan + Artemether answerCan you take Puravive with Artemether?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Puravive contains Panax ginseng.
Full Puravive + Artemether answerCan you take Tragacanth with Artemether?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tragacanth might alter absorption of oral drugs.
Full Tragacanth + Artemether answerCan you take Thyroid Extract with Artemether?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Food and medications can interfere with thyroid hormone absorption.
Full Thyroid Extract + Artemether answerCan you take Agar with Artemether?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Agar forms a thick gel, which may disrupt the absorption of nutrients and medications.
Full Agar + Artemether answerCan you take Algin with Artemether?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, algin can alter the absorption of oral drugs.
Full Algin + Artemether answerCan you take Black Psyllium with Artemether?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Full Black Psyllium + Artemether answerCan you take Blond Psyllium with Artemether?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Full Blond Psyllium + Artemether answerCan you take Carob with Artemether?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, carob might also impair the absorption of oral drugs.
Full Carob + Artemether answerCan you take Karaya Gum with Artemether?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Co-administration of oral drugs with bulk forming laxatives such as karaya gum may decrease, increase, or have no effect on the absorption o...
Full Karaya Gum + Artemether answerCan you take Marshmallow with Artemether?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Full Marshmallow + Artemether answerCan you take Xanthan Gum with Artemether?
Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, xanthan gum can alter the absorption of oral drugs due to its fiber qualities.
Full Xanthan Gum + Artemether answerCan you take Grapefruit with Artemether?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Grapefruit juice can increase blood levels of oral artemether, potentially increasing the effects and adverse effects of artemether.
Full Grapefruit + Artemether answerCan you take Activated Charcoal with Artemether?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the rout...
Full Activated Charcoal + Artemether answerCan you take Arsenic with Artemether?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Arsenic trioxide can prolong the QT interval.
Full Arsenic + Artemether answerCan you take Cesium with Artemether?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, taking cesium concomitantly with other drugs that prolong the QT interval may increase the risk of ventricular arrhythmias an...
Full Cesium + Artemether answerCan you take Ephedra with Artemether?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, ephedra might have an additive effect with drugs that prolong the QT interval.
Full Ephedra + Artemether answerCan you take Sida Cordifolia with Artemether?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, Sida cordifolia might increase the risk of additive QT interval prolongation when taken with QT interval-prolonging drugs.
Full Sida Cordifolia + Artemether answerCan you take American Hellebore with Artemether?
Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. American hellebore, also known as Veratrum viride, contains alkaloids that can potentially prolong the QT interval on an electrocardiogram (...
Full American Hellebore + Artemether answerCan you take Coffee Charcoal with Artemether?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Coffee charcoal can reduce the absorption of orally administered drugs and should be separated from oral drug administration by at least two...
Full Coffee Charcoal + Artemether answerWhat Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
How Does Our Interaction Checker Work?
Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).
So the check works in three steps: (1) Artemether is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Artemether, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.
Artemether sits in 3 interaction categories. Open any one to see what the group means:
Oral Drugs 17 ingredients
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
17 of the supplement ingredients on this page reach Artemether through this category.
Qt Interval-Prolonging Drugs 13 ingredients
Medications that can affect the heart's electrical rhythm (the QT interval). Supplements with similar effects can add to that risk.
13 of the supplement ingredients on this page reach Artemether through this category.
Artemether (Artenam, Paluther) 1 ingredient
A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.
1 of the supplement ingredient on this page reaches Artemether through this category.
Take a Supplement Product? Check the Whole Bottle Against Artemether
Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Artemether.
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Products that contain Artemether-interacting ingredients
Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Artemether.
Artemether & Supplements: Common Questions
What supplements interact with Artemether?
Which Artemether supplement interactions are the most serious?
Can I take vitamins or supplements while on Artemether?
Do brands like Artenam have the same supplement interactions as Artemether?
Where do these interaction ratings come from?
What about Artemether and my other medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Where This Data Comes From — and Why You Can Trust It
🧪 Licensed clinical database
Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.
🧑⚕️ Pharmacist review
This page is curated and coded by Dr. Brian Staiger, PharmD, BCPS, Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.
🔄 Kept current
Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 25, 2026.
🔍 Full transparency
How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.
Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.