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Dietary supplement

A.I. Aromatase Inhibitor Ingredients & Drug Interactions

by Swoll Mafia

A.I. Aromatase Inhibitor label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking A.I. Aromatase Inhibitor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

A.I. Aromatase Inhibitor is a dietary supplement by Swoll Mafia with 1 active ingredient. Its ingredients are commonly taken for lowering estrogen levels, post-cycle therapy after steroid or prohormone use, reducing gynecomastia ('gyno').Based on those ingredients, 4 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Androsta-3, 5-Diene-7, 17-Dione. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against A.I. Aromatase Inhibitor by Swoll Mafia

Ask about any prescription or over-the-counter medication and we check it for interactions with A.I. Aromatase Inhibitor by Swoll Mafia — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of A.I. Aromatase Inhibitor by Swoll Mafia

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Androsta-3, 5-Diene-7, 17-Dione, commonly called Arimistane. The capsule also holds inactive ingredients — rice flour, gelatin, and calcium silicate — which serve as filler and binder.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Arimistane product and its label doesn't state a use — see Arimistane's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold does not establish effectiveness for this ingredient. It's marketed for athletic performance, muscle strength, erectile dysfunction, sexual arousal, and obesity, but the data available to us shows insufficient reliable evidence to rate it for any of these purposes.

The evidence, ingredient by ingredient Arimistane

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The safety data for Arimistane is sparse, and regulatory agencies caution against aromatase inhibitor supplements because of the hormone-altering effects and limited safety testing. This ingredient is rated possibly unsafe in pregnancy — lowering estrogen during pregnancy could cause harm, so do not use it if you're pregnant.

There is no safety data during breastfeeding either, so it should be avoided while nursing. No adverse effects were reported in the data we hold, but the lack of side-effect reports does not mean the product is free from risk.

Side effects, ingredient by ingredient Arimistane

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Arimistane.
  • The most serious interaction on file is rated Moderate.
  • For scale: 4 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take a prescription aromatase inhibitor — used for certain cancers or other hormone-related conditions — check with your pharmacist before adding this supplement. A Moderate interaction is documented, and the effect could increase the risk of low-estrogen side effects and liver damage.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

This is a hormone-altering supplement with minimal safety data behind it. If you take any prescription aromatase inhibitor (such as anastrozole, letrozole, or exemestane), do not start this product without talking to your doctor.

Do not use if you're pregnant or breastfeeding. A conversation with your pharmacist before taking it is a good idea.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about A.I. Aromatase Inhibitor, straight from the product label.

Brand Swoll Mafia
Barcode (UPC) 123789345619
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2019
DSLD ID 200096
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for A.I. Aromatase Inhibitor by Swoll Mafia, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
123789345619
IngredientAmount% DV
Androsta-3, 5-Diene-7, 17-Dione30 mg--

Other ingredients: Rice Flower, Gelatin, Calcium Silicate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Administer 3 capsules once daily. Do not exceed 1 serving within 24 hours.

Precautions

Do not exceed 1 serving within 24 hours. Warning: Do not exceed recommended dosage. Consult with a physician before use.

Keep out of reach from children.

Do not administer if test subject is at risk or has health issues involving heart, kidney, liver, stroke, difficult urinating, depression, anxiety or seizure disorder.

All customers represent and warrant that through their own review and study that they are fully aware and knowledgeable about the following product. All customers must be 18 years old to purchase. Under no circumstance shall seller be liable for consequential damages, whether purchases claim contract, negligence, strict liability or otherwise. In purchasing this product the purchaser agrees to the above

For experimental use only Not for human consumption

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease or illness.

Seals/Symbols

Proudly made in the United States USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

A.I. Aromatase Inhibitor by Swoll Mafia label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

A.I. Aromatase Inhibitor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in A.I. Aromatase Inhibitor by Swoll Mafia

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Androsta-3, 5-Diene-7, 17-Dione

Interacts with
4 drugs
30 mg per serving

Arimistane (sometimes sold as Estrovade) is a synthetic aromatase inhibitor marketed as a dietary supplement to lower estrogen and raise testosterone,...

Androsta-3, 5-Diene-7, 17-Dione monograph & interactions

Other (inactive) ingredients: Rice Flower, Gelatin, Calcium Silicate. These complete the product’s ingredient list but are not active constituents.

Interaction report

A.I. Aromatase Inhibitor by Swoll Mafia Drug Interactions

Want to check YOUR meds against A.I. Aromatase Inhibitor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
4Drugs
4 Moderate

Ingredients driving the most interactions

Androsta-3, 5-Diene-7, 17-Dione 4

Individual Drug Interactions

The ingredients in A.I. Aromatase Inhibitor interact with 4 drugs. Click any drug to see the details.

1 of the 1 ingredient in A.I. Aromatase Inhibitor interact with drugs. Each result below shows which ingredient is responsible. Androsta-3, 5-Diene-7, 17-Dione

Each ingredient & the kinds of drugs it affects

For each ingredient in A.I. Aromatase Inhibitor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Androsta-3, 5-Diene-7, 17-Dione1 drug type · 4 drugs

Aromatase Inhibitors

It is believed that Arimistane inhibits the aromatase enzyme, which may interact with other aromatase inhibitors. This interaction could potentially increase the risk of side effects associated with low estrogen levels or from additive side effects, such as an increased risk of liver toxicity. It is recommended to consult with a healthcare provider before combining Arimistane with other aromatase inhibitors to assess the potential risks and benefits.

Likelihood Probable Evidence C
Androsta-3, 5-Diene-7, 17-Dione full monograph & interactions
The maker

Brand information

Manufacturer and brand details for A.I. Aromatase Inhibitor, from the product label.

Swoll Mafia

See all Swoll Mafia products
Name
Swoll Mafia
Pharmacist Counseling Corner

A.I. Aromatase Inhibitor by Swoll Mafia: Common Questions

Does A.I. Aromatase Inhibitor by Swoll Mafia interact with any medications?
Yes. Based on its ingredients, A.I. Aromatase Inhibitor has a known interaction with 4 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
A.I. Aromatase Inhibitor contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this supplement actually work for muscle strength or performance?
The evidence we hold is not strong enough to say. It's marketed for athletic performance and muscle strength, but the data available shows insufficient reliable evidence to rate it for those uses.
Can I take this while pregnant?
No. This ingredient is rated possibly unsafe in pregnancy because lowering estrogen during pregnancy could be harmful. Do not use it if you're pregnant or trying to become pregnant.
Is it safe while breastfeeding?
There is no safety data on this ingredient during breastfeeding, so it should be avoided. If you're nursing and interested in supplements, talk with your doctor or pharmacist about options with more safety information.
What does Arimistane actually do in the body?
It's believed to inhibit the aromatase enzyme, which is involved in converting other hormones to estrogen. That's why it's sold as an aromatase inhibitor supplement, though the evidence for its actual effects in people is limited.
What are the side effects?
No adverse effects were reported in the safety data we hold, but that doesn't mean they don't happen — the product simply hasn't been studied thoroughly. The main concern is that blocking the aromatase enzyme can lower estrogen and carry risks like liver toxicity.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

A.I. Aromatase Inhibitor label
Go deeper

The Full Monographs Behind A.I. Aromatase Inhibitor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Arimistane

Interacts with 4 drugs

Arimistane (sometimes sold as Estrovade) is a synthetic aromatase inhibitor marketed as a dietary supplement to lower estrogen and raise testosterone, often during or after steroid or prohor...

Read the full Arimistane monograph →
Sources

Sources & How We Checked

A.I. Aromatase Inhibitor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 1 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Arimistane 1 reference
  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed

See these in context on the Arimistane monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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