Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

RAD-140 Ingredients & Drug Interactions

by Swoll Mafia

RAD-140 label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking RAD-140 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

RAD-140 is a dietary supplement by Swoll Mafia with 1 active ingredient. Its ingredients are commonly taken for muscle building, athletic performance and bodybuilding, strength gains.Based on those ingredients, 370 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Testolone. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against RAD-140 by Swoll Mafia

Ask about any prescription or over-the-counter medication and we check it for interactions with RAD-140 by Swoll Mafia — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of RAD-140 by Swoll Mafia

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: testolone, an unapproved research compound being studied for potential effects on athletic performance, muscle strength, bone health, cancer, and wasting conditions. Creatine is also listed as an inactive ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Testolone product and its label doesn't state a use — see Testolone's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

There is insufficient reliable evidence to rate testolone for any of its proposed uses—athletic performance, muscle strength, osteoporosis, breast cancer, and cachexia (muscle wasting). The data we hold does not establish that it works for these purposes.

The evidence, ingredient by ingredient Testolone

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Testolone is an unapproved experimental drug with reported serious risks and should not be used. It is possibly unsafe overall.

Common adverse effects include decreased appetite, dehydration, elevated liver enzymes, vomiting, and weight loss. Rare but serious effects include acute heart muscle inflammation (myocarditis), low blood phosphate (hypophosphatemia), and liver injury.

A case of myocarditis was reported in a 32-year-old man using the product; he presented with shortness of breath and fever and required hospitalization. Abnormal hair growth and acne occurred in individual users.

Testolone is hormonally active and unstudied in pregnancy—do not use if pregnant. No safety data exist for breastfeeding; avoid completely if breastfeeding.

Side effects, ingredient by ingredient Testolone

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Testolone.
  • The most serious interaction on file is rated Moderate.
  • For scale: 371 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check any medications you use that stress the liver (hepatotoxic drugs)—testolone may add to their damaging effects on liver function, a Moderate-severity interaction. If you're on any medication at all, use the checker on this page to verify it first.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is an unapproved experimental compound with insufficient evidence of effectiveness and serious safety concerns, including liver injury and heart inflammation. It should not be used during pregnancy or breastfeeding.

Talk to your doctor before considering it, especially if you take any medications that affect the liver.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about RAD-140, straight from the product label.

Brand Swoll Mafia
Barcode (UPC) 151290958929
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2019
DSLD ID 200152
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for RAD-140 by Swoll Mafia, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
30
UPC/BARCODE
151290958929
IngredientAmount% DV
Testolone30 mg--

Other ingredients: Creatine

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: Administer 3 capsules once daily. Do not exceed 1 serving within 24 hours.

Precautions

Do not exceed 1 serving within 24 hours. Warning: Do not exceed recommended dosage. Consult with a physician before use.

Keep out of reach from children.

Do not administer if test subject is at risk or has health issues involving heart, kidney, liver, stroke, difficult urinating, depression, anxiety or seizure disorder.

All customers represent and warrant that through their own review and study that they are fully aware and knowledgeable about the following product. All customers must be 18 years old to purchase. Under no circumstance shall seller be liable for consequential damages, whether purchases claim contract, negligence, strict liability or otherwise. In purchasing this product the purchaser agrees to the above

For experimental use only Not for human consumption

Formula

Testolone

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease or illness.

Seals/Symbols

Proudly made in the United States USA

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

RAD-140 by Swoll Mafia label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

RAD-140 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in RAD-140 by Swoll Mafia

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Testolone

Interacts with
370 drugs
30 mg per serving

Testolone (RAD-140) is a synthetic experimental drug called a selective androgen receptor modulator (SARM), not a dietary supplement or herb, and it i...

Testolone monograph & interactions

Other (inactive) ingredients: Creatine. These complete the product’s ingredient list but are not active constituents.

Interaction report

RAD-140 by Swoll Mafia Drug Interactions

Want to check YOUR meds against RAD-140?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
370Drugs
370 Moderate

Ingredients driving the most interactions

Testolone 370

Individual Drug Interactions

The ingredients in RAD-140 interact with 370 drugs. Click any drug to see the details.

1 of the 1 ingredient in RAD-140 interact with drugs. Each result below shows which ingredient is responsible. Testolone

Each ingredient & the kinds of drugs it affects

For each ingredient in RAD-140 with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Testolone1 drug type · 370 drugs

Hepatotoxic Drugs

Theoretically, concomitant use might have additive hepatotoxic effects.
In a case report, a 52-year-old male was diagnosed with liver injury thought to be related to the use of products containing testolone. Also, elevated liver enzymes were commonly reported in a dose escalation study of testolone.

Likelihood Possible Evidence B
Testolone full monograph & interactions
The maker

Brand information

Manufacturer and brand details for RAD-140, from the product label.

Swoll Mafia

See all Swoll Mafia products
Name
Swoll Mafia
Pharmacist Counseling Corner

RAD-140 by Swoll Mafia: Common Questions

Does RAD-140 by Swoll Mafia interact with any medications?
Yes. Based on its ingredients, RAD-140 has a known interaction with 370 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
RAD-140 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is testolone actually approved by the FDA?
No. Testolone is an unapproved experimental drug. The FDA has warned about it, and it should not be used.
What are the most common side effects?
The most common reported effects are decreased appetite, dehydration, elevated liver enzymes, vomiting, and weight loss. Abnormal hair growth and acne have also been reported in individual users.
Can I take this if I'm pregnant or breastfeeding?
No. Testolone is hormonally active and unstudied in pregnancy—safety data advises against use. There's no safety data for breastfeeding either; avoid it completely if you're nursing.
Has anyone had serious problems from testolone?
Yes. A case of acute heart muscle inflammation (myocarditis) was reported in a 32-year-old man who used it for athletic enhancement; he required hospitalization. Liver injury has also been reported.
Does testolone actually build muscle or improve athletic performance?
There is insufficient reliable evidence to show that testolone works for muscle strength, athletic performance, or any other purpose. It is not established to be effective.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if RAD-140 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

RAD-140 label
Go deeper

The Full Monographs Behind RAD-140’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Testolone

Interacts with 370 drugs

Testolone (RAD-140) is a synthetic experimental drug called a selective androgen receptor modulator (SARM), not a dietary supplement or herb, and it is not approved or proven safe for human...

Read the full Testolone monograph →
Sources

Sources & How We Checked

RAD-140's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Testolone 7 references
  1. Joseph JF, Parr MK. Synthetic androgens as designer supplements. Curr Neuropharmacol. 2015;13(1):89-100. PubMed
  2. Warning Letter: Ironmag Labs 10/23/17. FDA Inspections, Compliance, Enforcement, and Criminal Investigations, October 23, 2017. https://www.fda.gov/iceci/enforcementactions/warningletters/2017/ucm582464.htm Accessed: November 1, 2017
  3. Warning Letter: Panther Sports Nutrition 10/23/17. FDA Inspections, Compliance, Enforcement, and Criminal Investigations, October 23, 2017. https://www.fda.gov/iceci/enforcementactions/warningletters/2017/ucm581630.htm. Accessed: November 1, 2017
  4. Warning Letter: Infantry Labs LLC 10/23/17. FDA Inspections, Compliance, Enforcement, and Criminal Investigations, October 23, 2017. https://www.fda.gov/iceci/enforcementactions/warningletters/2017/ucm582685.htm. Accessed: November 1, 2017
  5. LoRusso P, Hamilton E, Ma C, et al. A first-in-human phase 1 study of a novel selective androgen receptor modulator (SARM), RAD140, in ER+/HER2- metastatic breast cancer. Clin Breast Cancer 2022;22(1):67-77. PubMed
  6. Barbara M, Dhingra S, Mindikoglu AL. Drug-induced liver injury associated with alpha bolic (RAD-140) and alpha elite (RAD-140 and LGD-4033). ACG Case Rep J 2020;7(6):e00409. PubMed
  7. Padappayil RP, Chandini Arjun A, Vivar Acosta J, Ghali W, Mughal MS. Acute myocarditis from the use of selective androgen receptor modulator (SARM) RAD-140 (Testolone). Cureus. 2022;14(1):e21663. PubMed

See these in context on the Testolone monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team