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Dietary supplement

Acai 500 mg Ingredients & Drug Interactions

by Nature's Plus Herbal Actives

Acai 500 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Acai 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Acai 500 mg is a dietary supplement by Nature's Plus Herbal Actives with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, weight loss, energy and vitality.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Acai. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Acai 500 mg by Nature's Plus Herbal Actives

Ask about any prescription or over-the-counter medication and we check it for interactions with Acai 500 mg by Nature's Plus Herbal Actives — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Acai 500 mg by Nature's Plus Herbal Actives

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: acai, a berry from South America. You're getting 500 mg per capsule.

The remaining ingredients—microcrystalline cellulose, stearic acid, magnesium stearate, silica, and others—are fillers and binders that make up the capsule itself.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: nutritional support for free radical defense.
  • We looked for evidence on: oxidative stress, antioxidant protection, general wellness.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for acai is insufficient to say whether it works for any of the conditions it's marketed for. Our data covers aging skin, athletic performance, erectile dysfunction, and high cholesterol, and in each case the research isn't established enough to rate it.

If you're considering this supplement for one of those uses, you'd want to talk with your pharmacist or doctor about whether the evidence supports it.

The evidence, ingredient by ingredient Acai

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Acai is generally well tolerated as a food, but the safety and effects of concentrated supplements at higher doses haven't been well studied. There isn't enough safety information to know whether this supplement is okay to use during pregnancy or while breastfeeding, so caution is advised in both cases—talk with your pharmacist or doctor if you're pregnant, planning to become pregnant, or nursing before you start this product.

Side effects, ingredient by ingredient Acai

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Acai.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check any diabetes medications you take before starting this product. Acai may increase or decrease blood sugar, which could make your medication less effective or cause your blood sugar to swing unexpectedly.

Your pharmacist can help you monitor if you decide to use both.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

Acai supplement might appeal to you if you're looking for an antioxidant berry extract, but the evidence for its health benefits isn't established yet. If you take any diabetes medication, check with your pharmacist first—acai may affect your blood sugar control.

Pregnant or breastfeeding? Stick with your pharmacist or doctor before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 25, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Acai 500 mg, straight from the product label.

Brand Nature's Plus Herbal Actives
Barcode (UPC) 097467070981
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Aug 25, 2015
DSLD ID 49348
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Acai 500 mg by Nature's Plus Herbal Actives, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
097467070981
IngredientAmount% DV
Acai500 mg--

Other ingredients: Microcrystalline Cellulose, Stearic Acid, Magnesium Stearate, Silica, Activessence, Natural color, Vegetable Cellulose, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Nutritional Support for Free Radical Defense.*

Guaranteed Maximum Potency: Each Herbal Actives formula is scientifically standardized to the highest level of active principles.

HerbaShield: An exclusive purity and safety system including light-resistant bottle, airtight inner seal, moisture-absorbing packet, tamper-evident safety cap and tamper-proof full bottle seal.

THIS IS NOT A PRESCRIPTION PRODUCT. It is a dietary supplement made with the highest possible quality standards.

PRESCRIPTION QUALITY

Formula

Each Herbal Actives Acai capsule, providing the greatest concentration of active botanical principles, maximizes the synergistic benefits of the whole acai fruit, which naturally contains numerous flavonoids, including isovitexin, proanthocyanidins and anthocyanins.

HYPO-ALLERGENIC.

Acai 500 mg/50 mg polyphenols

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement offering the consistent benefits of exact potency, one capsule daily or as recommended by your health care professional.

Precautions

Note: If you are pregnant or nursing, consult your health care professional before using any herbal product.

Printed HerbaShield inner seal and full bottle seal. Do not use if either seal is missing or broken.

KEEP OUT OF REACH OF CHILDREN.

FDA Disclaimer Statement

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

Activessence(R) is a registered trademark of Triarco Industries, Inc. and protected by U.S. patents.

The Energy Supplements(R)

Vcaps(R) is a trademark of Capsugel(R)

(C)NATURAL ORGANICS(R)

Seals/Symbols

HerbaShield(R)

GUARANTEED MAXIMUM POTENCY(R)

GLUTEN Free

FDA Statement of Identity

STANDARDIZED BOTANICAL SUPPLEMENT

Formulation

Free from artificial colors, preservatives, yeast, wheat, soy and milk.

VEGETARIAN

Storage

KEEP TIGHTLY CLOSED IN A COOL, DRY PLACE.

General

Product No. 7098

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Acai 500 mg by Nature's Plus Herbal Actives label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Acai 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Acai 500 mg by Nature's Plus Herbal Actives

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Acai

Interacts with
86 drugs
500 mg per serving Form: Polyphenols

Acai is a nutritious Amazonian berry rich in antioxidants and healthy fats, and it is fine to enjoy as a food. However, strong human evidence is lacki...

Acai monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Stearic Acid, Magnesium Stearate, Silica, Activessence, Natural color, Vegetable Cellulose, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Acai 500 mg by Nature's Plus Herbal Actives Drug Interactions

Want to check YOUR meds against Acai 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Acai 86

Individual Drug Interactions

The ingredients in Acai 500 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Acai 500 mg interact with drugs. Each result below shows which ingredient is responsible. Acai

Each ingredient & the kinds of drugs it affects

For each ingredient in Acai 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Acai1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking acai with antidiabetes drugs might interfere with glycemic control.
Preliminary clinical research in healthy adults has shown that taking acai may increase or decrease levels of fasting blood glucose.

Likelihood Possible Evidence D
Acai full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Acai 500 mg, from the product label.

Nature's Plus Herbal Actives

Name
Natural Organics Laboratories, Inc. makers of Nature's Plus
Street Address
9500 New Horizons Blvd.
City
Amityville
State
New York
ZipCode
11701
Web Address
www.naturesplus.com
Pharmacist Counseling Corner

Acai 500 mg by Nature's Plus Herbal Actives: Common Questions

Does Acai 500 mg by Nature's Plus Herbal Actives interact with any medications?
Yes. Based on its ingredients, Acai 500 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Acai 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is acai safe to take if I'm pregnant or breastfeeding?
There isn't enough safety data on concentrated acai supplements during pregnancy or breastfeeding to know either way. Talk with your pharmacist or doctor before you start, since they can give you personalized advice based on your situation.
Does acai actually help with cholesterol, aging skin, or weight loss?
The research we have isn't strong enough to say. For all the conditions this supplement is marketed for—including high cholesterol, aging skin, athletic performance, erectile dysfunction, and weight loss—the evidence is insufficient to rate it.
What's in this supplement besides acai?
The capsule contains inactive ingredients like microcrystalline cellulose, stearic acid, magnesium stearate, silica, and vegetable cellulose—all standard fillers and binders.
Are there any side effects I should know about?
Acai hasn't reported side effects in our data, but keep in mind that concentrated supplements at high doses haven't been well studied, so there could be effects we don't know about yet.
Can I take this if I have diabetes?
Acai may affect your blood sugar levels up or down, which could interfere with your diabetes medication. Check with your pharmacist or doctor first, and they can help you monitor your blood sugar more closely if you use both together.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Acai 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Acai 500 mg label
Go deeper

The Full Monographs Behind Acai 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Acai

Interacts with 86 drugs

Acai is a nutritious Amazonian berry rich in antioxidants and healthy fats, and it is fine to enjoy as a food. However, strong human evidence is lacking for the bold health claims often atta...

Read the full Acai monograph →
Sources

Sources & How We Checked

Acai 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Acai 2 references
  1. Udani JK, Singh BB, Singh VJ, Barrett ML. Effects of acai (Euterpe oleracea Mart.) berry preparation on metabolic parameters in a healthy overweight population: a pilot study. Nutr J 2011;10:45.
  2. de Liz S, Cardoso AL, Copetti CLK, et al. Açaí (Euterpe oleracea Mart.) and juçara (Euterpe edulis Mart.) juices improved HDL-c levels and antioxidant defense of healthy adults in a 4-week randomized cross-over study. Clin Nutr. 2020;39(12):3629-3636. PubMed

See these in context on the Acai monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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