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Dietary supplement

Acai SuperFruit Ingredients & Drug Interactions

by NOW

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Acai SuperFruit is a dietary supplement by NOW with 2 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,053 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, organic Acai juice. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Acai SuperFruit by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 1 of its 2 active ingredients.

This product contains one active ingredient: organic acai juice. Acai is a fruit juice that's been studied for several health claims, though the evidence we hold doesn't yet support its use for aging skin, athletic performance, erectile dysfunction, high cholesterol, or weight management.

The other ingredients are inactive — they're mostly juices from other fruits (apple, pomegranate, raspberry, blueberry), plus citric acid, pectin, guar gum, natural flavoring, and potassium sorbate as a preservative. These serve to carry the acai juice, add flavor, and preserve the product.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Constipation — rated "Effective" (Black Psyllium) (Natural Medicines).
  • On file: Coronary heart disease (CHD) — rated "Likely Effective" (Black Psyllium) (Natural Medicines).

The evidence we hold doesn't establish that acai juice is effective for the claims often made about it. For aging skin, athletic performance, erectile dysfunction, high cholesterol, and obesity, the rating is insufficient reliable evidence to rate — meaning the data we have isn't robust enough to say whether it works or doesn't.

If you're considering acai for one of these reasons, talk to your pharmacist about what the current research actually shows and what your other options might be.

The evidence, ingredient by ingredient Black Psyllium Acai

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Acai is generally well tolerated when taken as a food or supplement. However, concentrated acai supplements — like this liquid — haven't been studied extensively at high doses, so there's a gap in what we know about long-term safety at supplement levels.

For pregnancy and breastfeeding, the safety data is limited. Acai as a food is likely fine, but concentrated supplements haven't been studied in pregnancy, so caution is advised.

Similarly, there isn't enough safety information on acai supplements during breastfeeding. If you're pregnant or breastfeeding, talk with your pharmacist or doctor before starting this product.

Side effects, ingredient by ingredient Black Psyllium Acai

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Black Psyllium, Acai.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications; lithium.
  • For scale: 2,054 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes drug (medication to lower your blood sugar), check your exact medication with the search tool on this page before adding acai juice. Acai may raise, lower, or have no effect on your blood sugar, so your prescriber needs to know you're taking it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Acai SuperFruit may appeal to you if you're looking for an antioxidant-rich juice supplement, but the evidence for its marketed health claims is thin. The main caution is if you take antidiabetes medication — acai's unpredictable effect on blood sugar means you should check with your pharmacist first.

If you're pregnant or breastfeeding, play it safe and ask your healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Acai SuperFruit, straight from the product label.

Brand NOW
Barcode (UPC) 733739048059
Net contents 32 fl. Oz.; 946 mL
Market status On market
Date entered into DSLD Dec 22, 2019
DSLD ID 212212
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Acai SuperFruit by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 fl. Oz.
Maximum serving Sizes:
1 fl. Oz.
Servings per container
32
UPC/BARCODE
733739048059
IngredientAmount% DV
Calories15 Calorie(s)--
Total Carbohydrates4 Gram(s)1%
Dietary Fiber2 Gram(s)7%
Added Sugars1 Gram(s)2%
Total Sugars2 Gram(s)--
organic Acai juice0 NP--

Other ingredients: Water, Apple juice concentrate, Pomegranate juice concentrate, Raspberry juice concentrate, Blueberry juice concentrate, Citric Acid, Guar Gum, Pectin, natural Acai flavor, Potassium Sorbate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 2 tablespoons ( 1 fl. oz.) daily, preferably in the morning.

Shake well before using.

Formula

NOW Acai delivers the natural nutrient profile in genuine whole foods.

Deep within the lush Brazilian rainforests of the Amazon grows one of our planet's most remarkable and nutritious fruits. Acai berries ( Euterpe oleracea) have remained highly esteemed throughout history by Brazilian natives because of their pleasant taste and their ability to promote optimal health and vitality. This product has 6,500 mg of acai concentrate per 1 oz. serving. Powerful free radical scavenger Acai berries abound in phytonutrients including polyphenols such as rutin, anthocyanins, and catechins. Acai also has ellagic acid. These and other compounds protect bodily tissues from free radical attack, a key factor of healthy aging. Healthy Immune System Support The nutrients and free radical quenchers present in acai help support healthy immune system function and its healthy response to transient, but normal metabolic stress by promoting proper nitric oxide (NO) production. Cardiovascular Support In addition to its powerful free radical quenching properties, acai supports proper NO production and healthy vascular response to biological signals. Each of these properties is important for the support of healthy heart and blood vessel function. Powerful Free Radical Scavenger Cardiovascular Support Natural phytonutrients, Ellagic acid, and fiber Supports healthy immune system function

Euterpe oleracea Fruit

Anthocyanins With pomegranate, raspberry & blueberry

Triangle K

Storage

Refrigerate after opening. Product should be consumed within 45 days of opening.

Precautions

Keep out of reach of children.

Caution: Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Tamper Resistant: Do not use if safety seal is broken.

FDA Statement of Identity

A dietary supplement

Formulation

Vegetarian/Vegan

Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Acai SuperFruit by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Acai SuperFruit by NOW

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 fl. Oz. Dosage formLiquid Servings per container32 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Dietary Fiber

Interacts with
2,025 drugs
2 Gram(s) per serving

Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...

Dietary Fiber monograph & interactions

Organic Acai juice

Interacts with
86 drugs
0 NP per serving

Acai is a nutritious Amazonian berry rich in antioxidants and healthy fats, and it is fine to enjoy as a food. However, strong human evidence is lacki...

Organic Acai juice monograph & interactions

Other (inactive) ingredients: Water, Apple juice concentrate, Pomegranate juice concentrate, Raspberry juice concentrate, Blueberry juice concentrate, Citric Acid, Guar Gum, Pectin, Natural Acai flavor, Potassium Sorbate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Acai SuperFruit by NOW Drug Interactions

Want to check YOUR meds against Acai SuperFruit?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2,053Drugs
89 Moderate 1,964 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Acai SuperFruit with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Dietary Fiber7 drug types · 2,025 drugs

Carbamazepine (Tegretol)

Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Lithium

Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.

Likelihood Probable Evidence D
Metformin (Glucophage)

Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.

Likelihood Possible Evidence D
Olanzapine (Zyprexa)

Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.

Likelihood Possible Evidence D
Digoxin (Lanoxin)

Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.

Likelihood Unlikely Evidence B
Ethinyl Estradiol

Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.

Likelihood Possible Evidence B

organic Acai juice1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking acai with antidiabetes drugs might interfere with glycemic control.
Preliminary clinical research in healthy adults has shown that taking acai may increase or decrease levels of fasting blood glucose.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Acai SuperFruit, from the product label.

NOW

See all NOW products
Name
NOW Foods
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowfoods.com
Pharmacist Counseling Corner

Acai SuperFruit by NOW: Common Questions

Does Acai SuperFruit by NOW interact with any medications?
Yes. Based on its ingredients, Acai SuperFruit has a known interaction with 2,053 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Acai SuperFruit contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will acai juice help me lose weight?
The evidence we hold is insufficient to say whether acai works for weight loss. It's marketed as a weight-loss aid, but the data doesn't yet back that claim. Talk to your pharmacist about weight-management strategies with stronger evidence behind them.
Is it safe to take acai if I'm pregnant?
There isn't enough safety data on concentrated acai supplements in pregnancy to say it's definitely safe. Acai as a food is likely fine, but this is a concentrated supplement. It's best to talk with your pharmacist or doctor before you start.
Can I take this with my diabetes medication?
You need to check with your pharmacist before you do. Acai may raise or lower your blood sugar, which could interfere with how your diabetes drug works. Your exact medication matters, so run it through the search tool on this page or ask your pharmacist directly.
What is acai, and what does it do?
Acai is a South American berry juice that's rich in antioxidants. It's been studied for claims like aging skin, athletic performance, and heart health, but the evidence we hold doesn't establish that it works for any of those uses yet.
Are there any side effects I should know about?
The product facts we have don't list specific side effects reported in trials. Acai is generally well tolerated, but because concentrated supplements haven't been studied at high doses, we don't have a complete safety picture. If you notice anything unusual after taking it, let your pharmacist know.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Acai SuperFruit is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Acai SuperFruit label
Sources

Sources & How We Checked

Acai SuperFruit's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Psyllium 18 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
  4. Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
  5. Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
  6. Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
  7. Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
  8. Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
  9. Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
  10. Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
  11. Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
  12. Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
  13. Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
  14. Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
  15. Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
  16. Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
  17. Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
  18. Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed

See these in context on the Black Psyllium monograph →

Acai 2 references
  1. Udani JK, Singh BB, Singh VJ, Barrett ML. Effects of acai (Euterpe oleracea Mart.) berry preparation on metabolic parameters in a healthy overweight population: a pilot study. Nutr J 2011;10:45.
  2. de Liz S, Cardoso AL, Copetti CLK, et al. Açaí (Euterpe oleracea Mart.) and juçara (Euterpe edulis Mart.) juices improved HDL-c levels and antioxidant defense of healthy adults in a 4-week randomized cross-over study. Clin Nutr. 2020;39(12):3629-3636. PubMed

See these in context on the Acai monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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