Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

ActivAMP AMPK 450 mg Ingredients & Drug Interactions

by AN Amazing Nutrition Amazing Formulas

ActivAMP AMPK 450 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking ActivAMP AMPK 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

ActivAMP AMPK 450 mg is a dietary supplement by AN Amazing Nutrition Amazing Formulas with 1 active ingredient. Its ingredients are commonly taken for fatigue and stress (adaptogen), blood sugar support, high blood pressure.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are ActivAMP Gynostemma pentaphyllum Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against ActivAMP AMPK 450 mg by AN Amazing Nutrition Amazing Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with ActivAMP AMPK 450 mg by AN Amazing Nutrition Amazing Formulas — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of ActivAMP AMPK 450 mg by AN Amazing Nutrition Amazing Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains one active ingredient: ActivAMP, which is an extract of jiaogulan (Gynostemma pentaphyllum), an herb traditionally used in Asia. The capsule also contains inactive ingredients—gelatin, rice powder, calcium silicate, vegetable magnesium stearate, and silica—which help form and preserve the capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: energy production and metabolic health support.
  • We looked for evidence on: Obesity, Diabetes, Cardiovascular disease (CVD), Hypercholesterolemia, Hypertension, Athletic performance — and 4 related terms.
  • The strongest evidence on file: Jiaogulan is rated "Possibly Effective" for Diabetes (Natural Medicines).
  • Also on file: Jiaogulan is rated "Insufficient Reliable Evidence To Rate" for Athletic performance, Cardiovascular disease (CVD), Hypercholesterolemia, Hypertension, and more.

Jiaogulan is possibly effective for diabetes based on clinical research showing it can lower blood glucose levels. For athletic performance, cancer, heart disease, nonalcoholic fatty liver disease, and respiratory infections, the evidence in our data is insufficient to rate whether it works.

If you're considering this supplement for one of those other uses, talk with your pharmacist about what the current science shows.

The evidence, ingredient by ingredient Jiaogulan

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Jiaogulan appears generally well tolerated in supplement form for short periods—up to about 4 months in studies—but we don't have solid data on long-term safety. The most common side effects are diarrhea and nausea; some people also report dry mouth, dizziness, or trouble sleeping.

During pregnancy, the safety data advises against use—we don't know enough to be sure it won't affect your baby. The same goes for breastfeeding: there isn't enough information, so you should avoid it while nursing.

Side effects, ingredient by ingredient Jiaogulan

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Jiaogulan.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking ActivAMP AMPK, double-check any blood thinners or antiplatelet drugs you're on—jiaogulan may raise bleeding risk. Do the same for antidiabetes medications (it can lower blood sugar too far) and any immunosuppressants.

Use the medication search tool on this page to look up your exact drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is mainly for people looking to help manage blood sugar, though the evidence is limited for other uses. If you take blood thinners, diabetes medications, or immunosuppressants, check with your pharmacist first.

Pregnant or breastfeeding? Skip it and talk to your doctor about safer options.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 27, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about ActivAMP AMPK 450 mg, straight from the product label.

Brand AN Amazing Nutrition Amazing Formulas
Barcode (UPC) 819209027288
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jul 27, 2021
DSLD ID 251359
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for ActivAMP AMPK 450 mg by AN Amazing Nutrition Amazing Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Quick Release Capsule(s)
Maximum serving Sizes:
2 Quick Release Capsule(s)
Servings per container
30
UPC/BARCODE
819209027288
IngredientAmount% DV
ActivAMP Gynostemma pentaphyllum Extract450 mg--

Other ingredients: Gelatin, Rice powder, Calcium Silicate, Vegetable Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

We believe that Amazing Nutrition is the key for healthy living. We are passionate about bringing you the finest selection of products which can perfectly complement a healthy diet and active lifestyle.

Shop online at: amazingnutrition.com Call toll-free: 1-800-526-0177 Vitamin angels Proud supporter

Formulation

AMP-activated protein kinase (AMPK) is an enzyme activated in skeletal muscle during exercise. When activated, AMPK stimulates energy production and decreases energy consuming processes such as protein and lipid synthesis.

Contains No: Preservatives, artificial color, flavor or sweetener, milk, lactose, soy, gluten, wheat or yeast.

Metabolic activator Supports metabolism & energy production Promotes healthy weight management Supports appetite control Made In USA

Amazing Nutrition an FDA regulated facility

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Caution: Not intended for use by pregnant or nursing women and children under the age of 18. If you are taking any medications, including blood thinners, planning any medical procedures or have any medical condition, consult your doctor before use.

Caution: Not intended for use by pregnant or nursing women and children under the age of 18.

Discontinue use and consult your doctor if any adverse reactions occur.

Storage

Store in a cool, dry place.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

GMP Good Manufacturing Practice Quality Product

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, adults take two (2) quick release capsules daily, preferably with a meal or as directed by a health care professional. Use with a reduced calorie diet and daily exercise program.

Brand IP Statement(s)

ActivAMP is a registered trademark of Gencor.

Formula

450 mg per serving

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

ActivAMP AMPK 450 mg by AN Amazing Nutrition Amazing Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

ActivAMP AMPK 450 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in ActivAMP AMPK 450 mg by AN Amazing Nutrition Amazing Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Quick Release Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

ActivAMP Gynostemma pentaphyllum Extract

Interacts with
327 drugs
450 mg per serving

Jiaogulan is a climbing vine used in traditional Chinese medicine as an adaptogen and for heart, blood sugar, and cholesterol support. Early human and...

ActivAMP Gynostemma pentaphyllum Extract monograph & interactions

Other (inactive) ingredients: Gelatin, Rice powder, Calcium Silicate, Vegetable Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

ActivAMP AMPK 450 mg by AN Amazing Nutrition Amazing Formulas Drug Interactions

Want to check YOUR meds against ActivAMP AMPK 450 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

ActivAMP Gynostemma pentaphyllum Extract 327

Individual Drug Interactions

The ingredients in ActivAMP AMPK 450 mg interact with 327 drugs. Click any drug to see the details.

1 of the 1 ingredient in ActivAMP AMPK 450 mg interact with drugs. Each result below shows which ingredient is responsible. ActivAMP Gynostemma pentaphyllum Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in ActivAMP AMPK 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

ActivAMP Gynostemma pentaphyllum Extract3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, jiaogulan might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research suggests that jiaogulan has antiplatelet effects.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, jiaogulan might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research shows that jiaogulan can lower blood glucose levels.

Likelihood Possible Evidence B
Immunosuppressants

Theoretically, jiaogulan might decrease the effectiveness of immunosuppressive therapy.
Clinical and animal studies suggest that jiaogulan can stimulate the immune system.

Likelihood Possible Evidence D
ActivAMP Gynostemma pentaphyllum Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for ActivAMP AMPK 450 mg, from the product label.

AN Amazing Nutrition Amazing Formulas

See all AN Amazing Nutrition Amazing Formulas products
Name
Amazing Nutrition
City
Jersey City
State
NJ
ZipCode
07310
Phone Number
1-800-526-0177
Web Address
amazingnutrition.com
Pharmacist Counseling Corner

ActivAMP AMPK 450 mg by AN Amazing Nutrition Amazing Formulas: Common Questions

Does ActivAMP AMPK 450 mg by AN Amazing Nutrition Amazing Formulas interact with any medications?
Yes. Based on its ingredients, ActivAMP AMPK 450 mg has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
ActivAMP AMPK 450 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is jiaogulan, and what does it do in this supplement?
Jiaogulan is a plant extract used in traditional Asian medicine. In this supplement, it's included because research suggests it may help lower blood sugar levels in people with diabetes, though evidence for other uses like athletic performance or heart health is limited.
Can I take this if I'm pregnant or breastfeeding?
No. The safety data advises against jiaogulan during pregnancy because we don't know if it could affect your baby's development. You should also avoid it while breastfeeding due to lack of safety information. Talk with your doctor about options that are safer for you and your baby.
What side effects might I experience?
The most common are diarrhea and nausea. Some people also report dry mouth, dizziness, or insomnia. These generally appear mild when jiaogulan is used short-term (up to 4 months), but long-term safety hasn't been thoroughly studied.
Is this supplement safe to take long-term?
Studies have tracked jiaogulan use for about 4 months and found it generally well tolerated, but we don't have solid data on what happens with long-term use. If you're thinking of taking it regularly, discuss that plan with your pharmacist or doctor.
Does this supplement actually work for diabetes?
Jiaogulan is possibly effective for diabetes—clinical research shows it can lower blood glucose. That said, it shouldn't replace prescribed diabetes medications. Talk with your doctor about whether it might help as part of your overall plan.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if ActivAMP AMPK 450 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

ActivAMP AMPK 450 mg label
Go deeper

The Full Monographs Behind ActivAMP AMPK 450 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Jiaogulan

Interacts with 327 drugs

Jiaogulan is a climbing vine used in traditional Chinese medicine as an adaptogen and for heart, blood sugar, and cholesterol support. Early human and animal studies are promising for some u...

Read the full Jiaogulan monograph →
Sources

Sources & How We Checked

ActivAMP AMPK 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Jiaogulan 8 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Tan H, Liu ZL, Liu MJ. [Antithrombotic effect of Gynostemma pentaphyllum]. Zhingguo Zhong Xi Yi Jie He Za Zhi 1993;13:278-80.
  3. Chan LY, Chiu PY, Lau TK. An in-vitro study of ginsenoside Rb(1)-induced teratogenicity using a whole rat embryo culture model. Hum Reprod 2003;18:2166-8..
  4. Huyen VT, Phan DV, Thang P, Hoa NK, Ostenson CG. Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients. J Nutr Metab. 2013;2013:765383. doi: 10.1155/2013/765383.
  5. Li Y, Lin W, Huang J, Xie Y, Ma W. Anti-cancer effects of Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan). Chin Med. 2016 Sep 27;11:43. Review. PubMed
  6. Huyen VT, Phan DV, Thang P, Ky PT, Hoa NK, Ostenson CG. Antidiabetic effect of add-on Gynostemma pentaphyllum extract therapy with sulfonylureas in type 2 diabetic patients. Evid Based Complement Alternat Med 2012; 452313.
  7. Huyen VT, Phan DV, Thang P, Hoa NK, Ostenson CG. Antidiabetic effect of Gynostemma pentaphyllum tea in randomly assigned type 2 diabetic patients. Horm Metab Res. 2010;42(5):353-7.
  8. Rao A, Clayton P, Briskey D. The effect of an orally-dosed Gynostemma pentaphyllum extract (ActivAMP®) on body composition in overweight, adult men and women: a double-blind, randomised, placebo-controlled study. J Hum Nutr Diet 2021.

See these in context on the Jiaogulan monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team