Activated Broccoli Vital Extracts 350 mg Ingredients & Drug Interactions
by Solaray
What is this page for?
First and foremost: checking Activated Broccoli Vital Extracts 350 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Activated Broccoli Vital Extracts 350 mg is a dietary supplement by Solaray with 3 active ingredients. Its ingredients are commonly taken for antioxidant support, detoxification support, general heart health.Based on those ingredients, 723 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic freeze-dried Broccoli sprouts, Broccoli seed extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Activated Broccoli Vital Extracts 350 mg by Solaray
Ask about any prescription or over-the-counter medication and we check it for interactions with Activated Broccoli Vital Extracts 350 mg by Solaray — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Activated Broccoli Vital Extracts 350 mg by Solaray
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
This product contains four active ingredients: organic freeze-dried broccoli sprouts, broccoli seed extract, sulforaphane glucosinolate, and myrosinase (an enzyme). Broccoli sprouts and sulforaphane are the compounds doing the work here — sulforaphane is a naturally occurring compound in broccoli, and myrosinase helps activate it in your digestive tract.
The remaining inactive ingredients are cellulose and calcium ascorbate (a form of vitamin C used as a preservative).
Does it work?
Not established
The evidence for what this supplement does is sparse. Sulforaphane is possibly effective for prostate cancer, but we don't have solid data yet.
For allergic rhinitis (hay fever), asthma, liver disease, and Helicobacter pylori infection, there isn't enough reliable evidence to say whether broccoli sprout or sulforaphane work. The bottom line: this is marketed as a health supplement, but clinical proof of benefit for most conditions isn't established in the data we have.
How safe is it?
Well-documented data
Broccoli sprouts as food are generally well tolerated, but this is a concentrated supplement — less studied and with variable quality. Side effects you might notice include loose stools, diarrhea, stomach cramping, or abdominal pain, especially at higher doses.
Sulforaphane can cause bowel discomfort, heartburn, stomach upset, headache, and vomiting. Rarely, sulforaphane has been linked to seizures in people with autism and seizure disorders, and to insomnia and irritability.
One concern: raw broccoli sprouts can carry food-borne bacteria like Salmonella or E. coli if grown improperly — cooking eliminates this risk, but supplements aren't cooked.
Meds to double-check
Moderate interaction found
Double-check any medications broken down by CYP3A4 enzymes (a major liver pathway) — sulforaphane may raise their levels. Also check drugs metabolized by CYP1A2, CYP2A6, and CYP2E1.
If you're on antiepileptic drugs or have a history of seizures, mention this supplement to your doctor first.
The bottom line
Scorecard at a glancePartially disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
If you don't take medications metabolized by your liver, this supplement is generally well tolerated, though digestive upset is common. If you're on any prescription drugs — especially heart, blood pressure, antidepressant, or antihistamine medications — check them against the tool below before you start.
Talk to your pharmacist about whether this product makes sense alongside your current regimen.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Activated Broccoli Vital Extracts 350 mg, straight from the product label.
| Brand | Solaray |
|---|---|
| Barcode (UPC) | 076280282467 |
| Net contents | 30 VegCap(s) |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2025 |
| DSLD ID | 325902 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Activated Broccoli Vital Extracts 350 mg by Solaray, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| organic freeze-dried Broccoli sprouts | 50 mg | -- |
| Broccoli seed extract | 350 mg | -- |
| Sulforaphane Glucosinolate | 35 mg | -- |
| Myrosinase | 0 NP | -- |
| Myrosinase | 13 mg | -- |
Other ingredients: Cellulose, Calcium Ascorbate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Solaray Est. 1973 A Brighter Way 1973
Formula
10% Sulforaphane Glucosinolates
Formulation
+ Heart health + Digestion
Vegan
FDA Statement of Identity
Dietary Supplement
Seals/Symbols
Lab Verified Vegan
General Statements
Since 1973, we've scoured the globe for the highest quality ingredients, connecting you with the most efficacious supplements that help you live brighter & embrace the moments that matter most.
100% PCR Bottles
Precautions
Warning: Do not use if safety seal is broken or missing. Keep your licensed health care practitioner informed when using this product.
Keep out of reach of children.
Suggested/Recommended/Usage/Directions
Directions: Use only as directed. Take 1 VegCap daily with a meal or glass of water.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Activated Broccoli Vital Extracts 350 mg by Solaray label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Activated Broccoli Vital Extracts 350 mg by Solaray
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 VegCap(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Organic freeze-dried Broccoli sprouts
Interacts with187 drugs
Broccoli sprouts are young broccoli seedlings rich in a compound called sulforaphane, which is being studied for antioxidant, anti-inflammatory, and d...
Organic freeze-dried Broccoli sprouts monograph & interactionsBroccoli seed extract
Interacts with187 drugs
Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...
Broccoli seed extract monograph & interactions- › Sulforaphane Glucosinolate
- › Myrosinase
Myrosinase
Other (inactive) ingredients: Cellulose, Calcium Ascorbate. These complete the product’s ingredient list but are not active constituents.
Activated Broccoli Vital Extracts 350 mg by Solaray Drug Interactions
HelloPharmacist Interaction Report
Solaray's Activated Broccoli Vital Extracts contains broccoli sprout and sulforaphane, both of which interact with medications your liver metabolizes.
The most serious concern is sulforaphane and drugs broken down by CYP3A4 enzymes (a major metabolic pathway) — sulforaphane may raise their levels and effects in your body, potentially causing overdose symptoms.
Read the full breakdown — every affected drug type, severity by severity
Broccoli sprout can reduce levels of drugs metabolized by CYP1A2 and CYP2A6 enzymes, making them less effective. Sulforaphane also affects CYP1A2 substrates (Moderate severity) and CYP2E1 substrates (Moderate severity), possibly increasing their levels.
We couldn't check myrosinase — no data is on file for it.
Altogether, these interactions span 713 individual medications. If you take prescription drugs, use the search tool on this page to check your exact medications before starting this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Activated Broccoli Vital Extracts 350 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Activated Broccoli Vital Extracts 350 mg interact with 723 drugs. Click any drug to see the details.
2 of the 3 ingredients in Activated Broccoli Vital Extracts 350 mg interact with drugs. Each result below shows which ingredient is responsible. organic freeze-dried Broccoli sprouts Broccoli seed extract
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Activated Broccoli Vital Extracts 350 mg — through 1 ingredient. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Read the full Sulforaphane Glucosinolate + Ado-trastuzumab Emtansine interactionAbemaciclibVerzenio
How Abemaciclib interacts with Activated Broccoli Vital Extracts 350 mg — through 1 ingredient. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Read the full Sulforaphane Glucosinolate + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Activated Broccoli Vital Extracts 350 mg — through 1 ingredient. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Read the full Sulforaphane Glucosinolate + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Activated Broccoli Vital Extracts 350 mg — through 1 ingredient. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Read the full Sulforaphane Glucosinolate + Abiraterone Acetate interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Activated Broccoli Vital Extracts 350 mg — through 1 ingredient. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Read the full Sulforaphane Glucosinolate + Acalabrutinib interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP2E1 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Aspirin interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Aspirin interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Aspirin, Caffeine interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Aspirin, Caffeine interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP2E1 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Butalbital interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Butalbital interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Broccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Butalbital, Caffeine interactionSulforaphane GlucosinolateCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Butalbital, Caffeine interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Butalbital, Caffeine, Codeine interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Butalbital, Codeine interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Butalbital, Codeine interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Broccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionSulforaphane GlucosinolateCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates Moderate
Interaction Summary
Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Butalbital, Codeine Phosphate interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Broccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionSulforaphane GlucosinolateCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP2E1 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Caffeine, Codeine interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Caffeine, Codeine interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Broccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionSulforaphane GlucosinolateCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Caffeine, Codeine, Salicylamide interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Caffeine, Dihydrocodeine interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Caffeine, Isometheptene interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Caffeine, Isometheptene interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Broccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Caffeine, Pyrilamine interactionSulforaphane GlucosinolateCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Caffeine, Pyrilamine interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Broccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionSulforaphane GlucosinolateCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Broccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionSulforaphane GlucosinolateCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP2E1 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Broccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Chlorpheniramine, Phenylephrine interactionSulforaphane GlucosinolateCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Chlorpheniramine, Phenylephrine interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 2e1 (cyp2e1) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP2E1 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Activated Broccoli Vital Extracts 350 mg — through 3 ingredients. Tap an ingredient for the detail:
Sulforaphane GlucosinolateCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2e1 (cyp2e1) Substrates +1 Moderate
Interaction Summary
Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Read the full Sulforaphane Glucosinolate + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionBroccoli Seed ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Read the full Broccoli Seed Extract + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionOrganic Freeze-dried Broccoli SproutsCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Read the full Organic Freeze-dried Broccoli Sprouts + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Activated Broccoli Vital Extracts 350 mg with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
organic freeze-dried Broccoli sprouts
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Animal research shows that broccoli sprout extract can increase CYP1A2 gene expression. Also, pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to glucosinolate constituents, which are also found in broccoli sprout.
Cytochrome P450 2A6 (Cyp2A6) Substrates
Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating broccoli 500 grams daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 is attributed to glucosinolate constituents, which are also found in broccoli sprout.
Broccoli seed extract
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.
Cytochrome P450 2A6 (Cyp2A6) Substrates
Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.
Brand information
Manufacturer and brand details for Activated Broccoli Vital Extracts 350 mg, from the product label.
Activated Broccoli Vital Extracts 350 mg by Solaray: Common Questions
Does Activated Broccoli Vital Extracts 350 mg by Solaray interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is this safe to take while pregnant or breastfeeding?
What's sulforaphane and why is it in here?
Can this actually prevent or treat cancer?
Will this give me diarrhea or stomach problems?
What if the broccoli sprouts are contaminated with bacteria?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Activated Broccoli Vital Extracts 350 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Broccoli Sprout
Interacts with 187 drugsBroccoli sprouts are young broccoli seedlings rich in a compound called sulforaphane, which is being studied for antioxidant, anti-inflammatory, and detoxification effects. Early research is...
Read the full Broccoli Sprout monograph → Herb & supplement monographBroccoli
Interacts with 187 drugsBroccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...
Read the full Broccoli monograph → Herb & supplement monographSulforaphane
Interacts with 722 drugsSulforaphane is a natural compound found in broccoli and other cruciferous vegetables that has shown promising antioxidant and anti-inflammatory effects in lab studies, but strong human evid...
Read the full Sulforaphane monograph →Sources & How We Checked
Activated Broccoli Vital Extracts 350 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 29 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Broccoli Sprout 8 references
- Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
- Pezdirc KB, Hure AJ, Blumfield ML, Collins CE. Listeria monocytogenes and diet during pregnancy; balancing nutrient intake adequacy v. adverse pregnancy outcomes. Public Health Nutr 2012;15(12):2202-9.
- Gorski L, Flaherty D, Duhe JM. Comparison of the stress response of Listeria monocytogenes strains with sprout colonization. J Food Prot 2008;71(8):1556-1562. PubMed
- Fahey JW, Ourisson PJ, Degnan FH. Pathogen detection, testing, and control in fresh broccoli sprouts. Nutr J 2006;5:13. PubMed
- Rajkowski KT, Boyd G, Thayer DW. Irradiation D-values for Escherichia coli O157:H7 and Salmonella sp. on inoculated broccoli seeds and effects of irradiation on broccoli sprout keeping quality and seed viability. J Food Prot 2003;66(5):760-766. PubMed
- Yoshida K, Ushida Y, Ishijima T, et al. Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver injury. World J Gastroenterol. 2015;21(35):10091-103. PubMed
- Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
- Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed
Broccoli 5 references
- Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
- Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
- Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
- Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
- Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed
Sulforaphane 16 references
- Park EJ, Pezzuto JM. Botanicals in cancer chemoprevention. Cancer Metastasis Rev 2002;21:231-55. PubMed
- Barcelo S, Mace K, Pfeifer AM, Chipman JK. Production of DNA strand breaks by N-nitrosodimethylamine and 2-amino-3-methylimidazo[4,5-f]quinoline in THLE cells expressing human CYP isoenzymes and inhibition by sulforaphane. Mutat Res 1998;402:111-20. PubMed
- Cipolla BG, Mandron E, Lefort JM, et al. Effect of sulforaphane in men with biochemical recurrence after radical prostatectomy. Cancer Prev Res (Phila). 2015;8(8):712-9. PubMed
- Fahey JW, Wade KL, Wehage SL, et al. Stabilized sulforaphane for clinical use: Phytochemical delivery efficiency. Mol Nutr Food Res. 2017 Apr;61(4). PubMed
- Alumkal JJ, Slottke R, Schwartzman J, et al. A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer. Invest New Drugs. 2015;33(2):480-9. PubMed
- Heber D, Li Z, Garcia-Lloret M, et al. Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles. Food Funct. 2014;5(1):35-41. PubMed
- Singh K, Connors SL, Macklin EA, et al. Sulforaphane treatment of autism spectrum disorder (ASD). Proc Natl Acad Sci U S A. 2014;111(43):15550-5. PubMed
- Wise RA, Holbrook JT, Criner G, et al. Lack of effect of oral sulforaphane administration on Nrf2 expression in COPD: A randomized, double-blind, placebo controlled trial. PLoS One. 2016;11(11):e0163716. PubMed
- Bent S, Lawton B, Warren T, et al. Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli. Mol Autism. 2018;9:35. PubMed
- Momtazmanesh S, Amirimoghaddam-Yazdi Z, Moghaddam HS, Mohammadi MR, Akhondzadeh S. Sulforaphane as an adjunctive treatment for irritability in children with autism spectrum disorder: A randomized, double-blind, placebo-controlled clinical trial. Psychiatr PubMed
- Fimognari C, Lenzi M, Hrelia P. Interaction of the isothiocyanate sulforaphane with drug disposition and metabolism: pharmacological and toxicological implications. Curr Drug Metab. 2008;9(7):668-78. PubMed
- Chinnappan SM, George A, Evans M, Anthony J. Efficacy of Labisia pumila and Eurycoma longifolia standardised extracts on hot flushes, quality of life, hormone and lipid profile of peri-menopausal and menopausal women: a randomised, placebo-controlled stud
- Mahéo K, Morel F, Langouët S, et al. Inhibition of cytochromes P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes. Cancer Res. 1997;57(17):3649-52.
- Yoxall V, Kentish P, Coldham N, Kuhnert N, Sauer MJ, Ioannides C. Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity. Int J Cancer. 2005;117(3):356-62. PubMed
- Zimmerman AW, Singh K, Connors SL, et al. Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder. Mol Autism 2021;12(1):38.
- Yusin J, Wang V, Henning SM, et al. The effect of broccoli sprout extract on seasonal grass pollen-induced allergic rhinitis. Nutrients 2021;13(4):1337. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC