African Mango Pure Ingredients & Drug Interactions
by GHI
What is this page for?
First and foremost: checking African Mango Pure against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
African Mango Pure is a dietary supplement by GHI with 1 active ingredient. Its ingredients are commonly taken for weight loss, appetite control, cholesterol support.Based on those ingredients, 94 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are African Mango extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against African Mango Pure by GHI
Ask about any prescription or over-the-counter medication and we check it for interactions with African Mango Pure by GHI — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of African Mango Pure by GHI
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Irvingia Gabonensis.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: diabetes medications.
- For scale: 94 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about African Mango Pure, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for African Mango Pure by GHI, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| African Mango extract | 1200 mg | -- |
Other ingredients: Gelatin, Calcium Carbonate, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Precautions
KEEP OUT OF REACH OF CHILDREN.
DO NOT USE IF SAFETY SEAL IS DAMAGED OR MISSING.
CAUTION: Do not exceed recommended dose.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.
Storage
STORE IN A COOL, DRY PLACE.
Seals/Symbols
Manufactured in the USA
GOOD MANUFACTURING PRACTICE GMP CONSISTENT QUALITY
Please Recycle
General Statements
GloabalHealthIdeas
Formulation
No Additives
Zero Fillers, Zero Binders, Zero Artificial Ingredients
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
SUGGESTED USE: Take one (1) capsule 2-3 times a day, 30 minutes before meals with an 8oz glass of water.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
African Mango Pure by GHI label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in African Mango Pure by GHI
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
African Mango extract
Interacts with94 drugs
Irvingia gabonensis (African mango) is a seed extract marketed mainly for weight loss and metabolic health. A few small studies suggest possible benef...
African Mango extract monograph & interactionsOther (inactive) ingredients: Gelatin, Calcium Carbonate, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
African Mango Pure by GHI Drug Interactions
African Mango Pure contains a single active ingredient, and it has known interactions with 94 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against African Mango Pure?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in African Mango Pure interact with 94 drugs. Click any drug to see the details.
1 of the 1 ingredient in African Mango Pure interact with drugs. Each result below shows which ingredient is responsible. African Mango extract
LixisenatideAdlyxin
How Lixisenatide interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Lixisenatide interactionMetforminGlucophage, Metformin
How Metformin interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Metformin interactionMetformin HydrochlorideRiomet ER
How Metformin Hydrochloride interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Metformin Hydrochloride interactionMetformin XrGlucophage XR
How Metformin Xr interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Metformin Xr interactionMetformin, LinagliptinJentadueto
How Metformin, Linagliptin interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Metformin, Linagliptin interactionMetformin, RosiglitazoneAvandamet
How Metformin, Rosiglitazone interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Metformin, Rosiglitazone interactionMetformin, SitagliptinJanumet, Janumet XR
How Metformin, Sitagliptin interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Metformin, Sitagliptin interactionMethyltestosteroneAndroid 10, Android 25, Metandren, Methitest, Oreton, Testred +1 more
How Methyltestosterone interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractTestosterone Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with testosterone products drugs might cause additive effects in some patients.
Read the full African Mango Extract + Methyltestosterone interactionMethyltestosterone BuccalAndroid 5, Oreton Buccal
How Methyltestosterone Buccal interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractTestosterone Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with testosterone products drugs might cause additive effects in some patients.
Read the full African Mango Extract + Methyltestosterone Buccal interactionMiglitolGlyset
How Miglitol interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Miglitol interactionMuraglitazarPargluva
How Muraglitazar interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Muraglitazar interactionNateglinideStarlix
How Nateglinide interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Nateglinide interactionPioglitazoneActos
How Pioglitazone interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Pioglitazone interactionPramlintideSymlin
How Pramlintide interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Pramlintide interactionRepaglinideGlucoNorm, Prandin
How Repaglinide interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Repaglinide interactionRosiglitazone MaleateAvandia
How Rosiglitazone Maleate interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Rosiglitazone Maleate interactionSaxagliptinOnglyza
How Saxagliptin interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Saxagliptin interactionSaxagliptin, Metformin XrKombiglyze
How Saxagliptin, Metformin Xr interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Saxagliptin, Metformin Xr interactionSemaglutideOzempic, Rybelsus, Wegovy
How Semaglutide interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Semaglutide interactionSimvastatin, SitagliptinJuvisync
How Simvastatin, Sitagliptin interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Simvastatin, Sitagliptin interactionSitagliptinJanuvia, Zituvio
How Sitagliptin interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Sitagliptin interactionSitagliptin, MetforminZituvimet
How Sitagliptin, Metformin interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Sitagliptin, Metformin interactionSotagliflozinInpefa
How Sotagliflozin interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Sotagliflozin interactionTestosteroneAndrogel, Andropatch, Delatestryl, Intrinsa, Natesto, Nebido +3 more
How Testosterone interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractTestosterone Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with testosterone products drugs might cause additive effects in some patients.
Read the full African Mango Extract + Testosterone interactionTestosterone EnanthateXyosted
How Testosterone Enanthate interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractTestosterone Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with testosterone products drugs might cause additive effects in some patients.
Read the full African Mango Extract + Testosterone Enanthate interactionTestosterone UndecanoateAndriol, Aveed, Jatenzo, Kyzatrex
How Testosterone Undecanoate interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractTestosterone Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with testosterone products drugs might cause additive effects in some patients.
Read the full African Mango Extract + Testosterone Undecanoate interactionTirzepatideMounjaro, Zepbound
How Tirzepatide interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Tirzepatide interactionTobutamideMobenol
How Tobutamide interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Tobutamide interactionTolazamideTolinase
How Tolazamide interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Tolazamide interactionTolbutamideOrinase
How Tolbutamide interacts with African Mango Pure — through 1 ingredient. Tap an ingredient for the detail:
African Mango ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Read the full African Mango Extract + Tolbutamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in African Mango Pure with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
African Mango extract
Antidiabetes Drugs
Theoretically, taking Irvingia gabonensis with antidiabetes drugs might increase the risk of hypoglycemia in some patients.
Human research shows that Irvingia gabonensis decreases blood sugar in diabetic patients being treated with antidiabetes agents. Monitor blood glucose levels closely. Dose adjustments might be necessary.
Testosterone
Theoretically, taking Irvingia gabonensis with testosterone products drugs might cause additive effects in some patients.
Animal research suggests that Irvingia gabonensis increases testosterone levels. The mechanism of action is unclear. Until more is known, advise patients taking testosterone to avoid using or use Irvingia gabonensis cautiously.
Brand information
Manufacturer and brand details for African Mango Pure, from the product label.
African Mango Pure by GHI: Common Questions
Does African Mango Pure by GHI interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if African Mango Pure is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind African Mango Pure’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
African Mango Pure's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Irvingia Gabonensis 7 references
- Oben JE, Ngondi JL, Momo CN, et al. The use of Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study. Lipids Health Dis 2008;7:12.
- Ngondi JL, Etoundi BC, Nyangono CB, et al. IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controll
- Adamson, I., Okafor, C., and Abu-Bakare, A. A supplement of Dikanut (Irvingia gabonesis) improves treatment of type II diabetics. West Afr.J.Med. 1990;9(2):108-115.
- Adamson, I., Okafor, C., and Abu-Bakare, A. Erythrocyte membrane ATPases in diabetes: effect of dikanut (Irvingia gabonensis). Enzyme 1986;36(3):212-215. PubMed
- Wolfe OA, Ijeoma UF. Effects of aqueous extracts of Irvingia gabonensis seeds on the hormonal parameters of male guinea pigs. Asian Pacific Journal of Tropical Medicine. 2010;3(3):200-204. DOI
- Kilinçalp S, Basar O, Coban S, Yüksel I. Irvingia gabonensis (African mango): innocent magic formula? Acta Gastroenterol Belg 2014;77(1):75-6.
- Nonsa-Ard R, Aneknan P, Tong-Un T, Honsawek S, Leelayuwat N. Effects of Irvingia gabonensis Extract on Metabolism, Antioxidants, Adipocytokines, Telomere Length, and Aerobic Capacity in Overweight/Obese Individuals. Nutrients 2022;14(21):4646. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC