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Dietary supplement

AgmaSet Ingredients & Drug Interactions

by Gilad&Gilad

AgmaSet label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking AgmaSet against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

AgmaSet is a dietary supplement by Gilad&Gilad with 1 active ingredient. Its ingredients are commonly taken for pre- and post-workout support, muscle pumps and exercise performance, cognitive support and mood.Based on those ingredients, 258 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Agmatine Sulfate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against AgmaSet by Gilad&Gilad

Ask about any prescription or over-the-counter medication and we check it for interactions with AgmaSet by Gilad&Gilad — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of AgmaSet by Gilad&Gilad

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

AgmaSet is a single-ingredient supplement containing agmatine sulfate. The inactive ingredients are gelatin, titanium dioxide, and water.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Agmatine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: healthy nerve function.
  • We looked for evidence on: Peripheral neuropathy, Herniated disc, neuropathic pain, nerve damage.
  • The closest evidence on file: Agmatine is rated "Insufficient Reliable Evidence To Rate" for Peripheral neuropathy (Natural Medicines).
  • Also on file: Agmatine is rated "Insufficient Reliable Evidence To Rate" for Herniated disc.

The evidence for agmatine sulfate is limited. According to our data, there is insufficient reliable evidence to rate its effectiveness for alcohol use disorder, Alzheimer disease, anxiety, athletic performance, autism spectrum disorder, or bipolar disorder.

If you're considering this product for a specific condition, talk with your pharmacist or doctor about what the research currently shows.

The evidence, ingredient by ingredient Agmatine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use of agmatine sulfate appears generally well tolerated, but long-term safety in humans hasn't been well studied. The most common side effects in trial use were diarrhea, indigestion (dyspepsia), and nausea — mild-to-moderate diarrhea and nausea appeared in a few trial participants within 2–3 days and resolved when they stopped taking it.

There isn't enough safety data to recommend agmatine during pregnancy or while breastfeeding. If you're pregnant, planning pregnancy, or nursing, talk with your doctor or pharmacist before starting this product.

Side effects, ingredient by ingredient Agmatine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Agmatine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 258 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking AgmaSet, double-check any blood pressure medications you're on — agmatine may lower your blood pressure further. Also verify any diabetes medications, since agmatine may increase the risk of low blood sugar.

Use the interaction checker on this page with your exact medication names.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

AgmaSet may be worth considering if you're interested in agmatine for general wellness, but the evidence for specific uses remains thin. If you take blood pressure or diabetes medications, check your exact drugs with our tool before you start.

Long-term safety data is limited, so talk with your pharmacist about whether short-term use fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about AgmaSet, straight from the product label.

Brand Gilad&Gilad
Barcode (UPC) 711978435700
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Dec 22, 2019
DSLD ID 208882
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies, Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for AgmaSet by Gilad&Gilad, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
711978435700
IngredientAmount% DV
Calories1 Calorie(s)--
Agmatine Sulfate890 mg--

Other ingredients: Gelatin, Titanium Dioxide, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

For healthy nerve functions

For nerve health

No allergens, preservatives or additives. Gluten-free.

Suggested/Recommended/Usage/Directions

Directions for use: Adults, 2 capsules twice or three-times daily with or after meals, or as recommended by your physician, pharmacist or healthcare professional.

Precautions

Note - Pregnant or nursing women, children and ill or medication-taking people should consult a physician before use.

Note - Pregnant or nursing women, children and ill or medication-taking people should consult a physician before use.

May cause diarrhea.

Keep out of the reach of children.

Do not use if printed seal is broken or missing.

Storage

Store in a closed bottle at temperature not exceeding 30 degrees C (86 degrees F) and humidity not above 70% RH.

Each bottle contains one (1) nontoxic desiccant packet.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

The exclusive G-Agmatine source

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

G-Agmatine is a trademark brand of Gilad&Gilad LLC. Patents U.S. 8,916,612; U.S. 9,585,852.

General Statements

Made in the USA

Natural Products Foundation Truth in advertising

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

AgmaSet by Gilad&Gilad label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

AgmaSet label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in AgmaSet by Gilad&Gilad

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Agmatine Sulfate

Interacts with
258 drugs
890 mg per serving

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most...

Agmatine Sulfate monograph & interactions

Other (inactive) ingredients: Gelatin, Titanium Dioxide, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

AgmaSet by Gilad&Gilad Drug Interactions

Want to check YOUR meds against AgmaSet?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
258Drugs
258 Moderate

Ingredients driving the most interactions

Agmatine Sulfate 258

Individual Drug Interactions

The ingredients in AgmaSet interact with 258 drugs. Click any drug to see the details.

1 of the 1 ingredient in AgmaSet interact with drugs. Each result below shows which ingredient is responsible. Agmatine Sulfate

Each ingredient & the kinds of drugs it affects

For each ingredient in AgmaSet with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Agmatine Sulfate2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, agmatine might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggest that agmatine has mild hypoglycemic effects.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, agmatine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that agmatine can modestly decrease heart rate and blood pressure.

Likelihood Possible Evidence D
Agmatine Sulfate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for AgmaSet, from the product label.

Gilad&Gilad

See all Gilad&Gilad products
Name
Gilad&Gilad LLC
City
Henderson
State
NV
ZipCode
89015
Phone Number
1-888-484-4523
Web Address
www.ForNerveHealth.com
Pharmacist Counseling Corner

AgmaSet by Gilad&Gilad: Common Questions

Does AgmaSet by Gilad&Gilad interact with any medications?
Yes. Based on its ingredients, AgmaSet has a known interaction with 258 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
AgmaSet contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is agmatine sulfate, and what does it do?
Agmatine sulfate is a compound that's been studied for various uses including mood, brain health, and athletic performance. Animal research shows it can modestly affect heart rate and blood pressure and has mild blood-sugar-lowering effects, but human evidence for specific conditions is limited.
What are the side effects of AgmaSet?
Short-term use is generally well tolerated. The most common side effects reported in trials were diarrhea, indigestion, and nausea — usually mild to moderate and appearing within a few days. They resolved once people stopped taking it.
Can I take AgmaSet while pregnant or breastfeeding?
There isn't enough safety data to recommend agmatine during pregnancy or while breastfeeding. Talk with your doctor or pharmacist about your individual situation before starting this product.
Is agmatine sulfate safe for long-term use?
Short-term use appears generally well tolerated, but long-term safety in humans hasn't been well studied. If you're thinking about using this long-term, discuss it with your pharmacist.
Can I take AgmaSet with my blood pressure or diabetes medications?
Agmatine may add to the blood-pressure-lowering effect of antihypertensive drugs and raise the risk of low blood pressure, and it may increase hypoglycemia risk with diabetes medications. Check your exact medications using the interaction tool on this page before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

AgmaSet label
Go deeper

The Full Monographs Behind AgmaSet’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Agmatine

Interacts with 258 drugs

Agmatine is a compound your body makes from the amino acid arginine, and it is sold mainly as a workout and 'pump' supplement. Human evidence for most of its claimed benefits is limited and...

Read the full Agmatine monograph →
Sources

Sources & How We Checked

AgmaSet's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Agmatine 3 references
  1. Piletz JE, Aricioglu F, Cheng JT, et al. Agmatine: clinical applications after 100 years in translation. Drug Discov Today 2013;18(17-18):880-93. PubMed
  2. Keynan O, Mirovsky Y, Dekel S, Gilad VH, Gilad GM. Safety and efficacy of dietary agmatine sulfate in lumbar disc-associated radiculopathy. An open-label, dose-escalating study followed by a randomized, double-blind, placebo-controlled trial. Pain Med 201 PubMed
  3. Shopsin B. The clinical antidepressant effect of exogenous agmatine is not reversed by parachlorophenylalanine: a pilot study. Acta Neuropsychiatr 2013;25(2):113-8. PubMed

See these in context on the Agmatine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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