Interactions on record — worth a quick check against your medications. Based on 1 of 3 ingredients. Check your meds →
Dietary supplement

Ammonium Chloride Buffered Ingredients & Drug Interactions

by Allergy Research Group

Ammonium Chloride Buffered label
See full label image
Tablet Or Pill Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ammonium Chloride Buffered against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Ammonium Chloride Buffered is a dietary supplement by Allergy Research Group with 3 active ingredients. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Ammonium Chloride Buffered by Allergy Research Group

Ask about any prescription or over-the-counter medication and we check it for interactions with Ammonium Chloride Buffered by Allergy Research Group — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Ammonium Chloride Buffered by Allergy Research Group

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 3 active ingredients: potassium, chloride, and ammonium. Potassium is an essential mineral that helps your heart, muscles, and nerves work properly.

The chloride and ammonium components support acid-base balance in your body. The tablet also contains inactive ingredients — dicalcium phosphate, silicon dioxide, magnesium stearate, croscarmellose sodium, and stearic acid — which help hold the pill together and aid absorption.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Potassium product and its label doesn't state a use — see Potassium's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

We hold no effectiveness ratings for this product in our data. If you're considering it for a specific health goal, that's a good question to bring to your doctor or pharmacist — they can tell you whether the evidence supports using it for your particular situation.

The evidence, ingredient by ingredient Potassium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Potassium from food is generally safe, but supplements can push your blood level dangerously high, especially if you have kidney disease. The most common side effects from oral potassium are abdominal pain, belching, diarrhea, bloating, nausea, and vomiting.

In rare cases, very high potassium levels can cause an irregular heartbeat, low blood pressure, or confusion — these need immediate attention. The safety data on potassium shows it's likely safe in pregnancy and breastfeeding when you eat it normally from food.

However, don't use potassium supplements during pregnancy or while breastfeeding without checking with your doctor or pharmacist first — they need to know your individual situation.

Side effects, ingredient by ingredient Potassium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check with your doctor or pharmacist if you're on a potassium-sparing diuretic, ACE inhibitor, or angiotensin receptor blocker (ARB). All three categories carry a Moderate risk of raising your blood potassium too high.

We could not check chloride and ammonium against medications in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take a blood pressure or heart medication, especially a potassium-sparing diuretic, ACE inhibitor, or ARB, you'll need to clear this product with your doctor or pharmacist before starting. Potassium can build up to unsafe levels when combined with certain drugs.

Everyone else should still talk it over with their own healthcare provider to make sure it fits your needs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ammonium Chloride Buffered, straight from the product label.

Brand Allergy Research Group
Barcode (UPC) 713947727106
Net contents 90 Tablet(s)
Market status On market
Date entered into DSLD Apr 25, 2013
DSLD ID 20133
Product type Mineral
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), No Allergies
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ammonium Chloride Buffered by Allergy Research Group, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
90
UPC/BARCODE
713947727106
IngredientAmount% DV
Potassium4 mg1%
Chloride322 mg9%
Ammonium164 mg--

Other ingredients: Dicalcium Phosphate, Silicon Dioxide, Magnesium Stearate, Croscarmellose Sodium, Stearic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

dietary supplement

Formula

Ammonium Chloride (Buffered)

HYPOALLERGENIC

General Statements

Buffered Ammonium Chloride is a systemic acidifier, to help maintain pH within normal levels.

Suggested/Recommended/Usage/Directions

Suggested Use As a dietary supplement, 1 tablet one to three times daily with meals, or as directed by a healthcare practitioner.

Precautions

CAUTION: May have a gentle diuretic effect.

Not recommended for children under 12 years unless under the supervision of a healthcare practitioner.

Storage

Keep in a cool, dry place, tightly capped.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

Rev. 002

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ammonium Chloride Buffered by Allergy Research Group label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ammonium Chloride Buffered label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ammonium Chloride Buffered by Allergy Research Group

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Potassium

Interacts with
62 drugs
4 mg per serving Form: Potassium Phosphate

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Chloride

322 mg per serving Form: Ammonium Chloride

Ammonium

164 mg per serving Form: Ammonium Chloride

Other (inactive) ingredients: Dicalcium Phosphate, Silicon Dioxide, Magnesium Stearate, Croscarmellose Sodium, Stearic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ammonium Chloride Buffered by Allergy Research Group Drug Interactions

Want to check YOUR meds against Ammonium Chloride Buffered?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Potassium 62

Individual Drug Interactions

The ingredients in Ammonium Chloride Buffered interact with 62 drugs. Click any drug to see the details.

1 of the 3 ingredients in Ammonium Chloride Buffered interact with drugs. Each result below shows which ingredient is responsible. Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Ammonium Chloride Buffered with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ammonium Chloride Buffered, from the product label.

Allergy Research Group

See all Allergy Research Group products
Name
Allergy Research Group
City
Alameda
State
CA
ZipCode
94502
Web Address
www.allergyresearchgroup.com
Pharmacist Counseling Corner

Ammonium Chloride Buffered by Allergy Research Group: Common Questions

Does Ammonium Chloride Buffered by Allergy Research Group interact with any medications?
Yes. Based on its ingredients, Ammonium Chloride Buffered has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ammonium Chloride Buffered contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is potassium safe during pregnancy and breastfeeding?
Potassium from food is fine during pregnancy and breastfeeding. But if you're thinking about taking a potassium supplement, talk with your doctor or pharmacist first — they need to weigh your individual health and what you eat before giving you the all-clear.
What are the side effects of potassium supplements?
Most commonly you might get an upset stomach — belching, bloating, nausea, diarrhea, or abdominal pain. Rarely, dangerously high potassium levels can cause an irregular heartbeat, low blood pressure, or confusion, which need immediate medical attention.
Can I take this if I have kidney disease?
That's a conversation you need to have with your doctor. Your kidneys control how much potassium stays in your blood, so kidney disease changes the picture — supplements can be risky for you in ways they might not be for others.
What exactly does potassium do in my body?
Potassium helps your heart beat, your muscles contract, and your nerves send signals. It's essential for normal body function, which is why your blood level matters — too much or too little both cause problems.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ammonium Chloride Buffered is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ammonium Chloride Buffered label
Go deeper

The Full Monographs Behind Ammonium Chloride Buffered’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph →
Sources

Sources & How We Checked

Ammonium Chloride Buffered's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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