Interactions on record — worth a quick check against your medications. Based on 6 of 11 ingredients. Check your meds →
Dietary supplement

Ancient Probiotics Women's Once Daily Ingredients & Drug Interactions

by Ancient Nutrition

Ancient Probiotics Women's Once Daily label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ancient Probiotics Women's Once Daily against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Ancient Probiotics Women's Once Daily is a dietary supplement by Ancient Nutrition with 11 active ingredients. Its ingredients are commonly taken for stress and anxiety, blood sugar support, respiratory complaints.Based on those ingredients, 614 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fenugreek seed extract, Holy Basil Leaf Extract, Lactobacillus acidophilus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Ancient Probiotics Women's Once Daily by Ancient Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Ancient Probiotics Women's Once Daily by Ancient Nutrition — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Ancient Probiotics Women's Once Daily by Ancient Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 11 active ingredients.
  • “Women's Herbal Blend” is a proprietary blend — the label gives one combined amount (421 mg) without saying how much of each component you get.
  • “Women's Probiotic Blend” is a proprietary blend — the label gives one combined amount (166 mg) without saying how much of each component you get.

This supplement contains 11 active ingredients — six probiotic bacterial and yeast strains, plus herbal extracts. The live organisms are Lactobacillus plantarum, Lactobacillus rhamnosus, Lactobacillus acidophilus, Bacillus coagulans, Saccharomyces boulardii, Bifidobacterium animalis lactis, and Lactobacillus gasseri.

They're complemented by Holy Basil Leaf Extract, Triphala fruit extract, and Fenugreek seed extract, all intended to support digestive and women's health. The product also contains inactive ingredients — Hypromellose (a capsule material), Rice Fiber, and Rice extract Blend — which are fillers and binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Supports healthy digestive function and elimination.
  • We looked for evidence on: Antibiotic-associated diarrhea, Clostridioides difficile infection, Constipation, Diarrhea, Flatulence, Inflammatory bowel disease (IBD) — and 3 related terms.
  • The strongest evidence on file: Saccharomyces Boulardii is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Saccharomyces Boulardii is rated "Possibly Effective" for Rotaviral diarrhea, Travelers' diarrhea, Clostridioides difficile infection.
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea.

The evidence for what this product can do varies by ingredient and use. Lactobacillus acidophilus is possibly effective for irritable bowel syndrome, Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis.

Bacillus coagulans is possibly effective for constipation and irritable bowel syndrome. Saccharomyces boulardii (the yeast) shows possibly effective evidence for rotaviral diarrhea, travelers' diarrhea, antibiotic-associated diarrhea, necrotizing enterocolitis, Clostridioides difficile infection, and Helicobacter pylori infection.

Fenugreek seed is possibly effective for sexual dysfunction, sexual arousal, dysmenorrhea, and diabetes. For Holy Basil Leaf Extract and the other probiotics in this formula, the evidence we hold isn't established — the data rates them as having insufficient reliable evidence for the conditions they're marketed to address.

The evidence, ingredient by ingredient Holy Basil Fenugreek Lactobacillus Acidophilus Bacillus Coagulans Saccharomyces Boulardii Lactobacillus Gasseri

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. Bacillus coagulans is generally well tolerated in healthy adults, though evidence and product quality vary.

Saccharomyces boulardii is generally safe for healthy adults but should be avoided by people who are critically ill or immunocompromised. Rarely, any live probiotic organism can cause infection (bacteremia or sepsis) in very ill patients with central catheters, but this is uncommon in relatively healthy people with intact immune systems.

Gastrointestinal side effects like bloating, flatulence, abdominal pain, and nausea can occur with probiotics but are uncommon. Holy Basil Leaf Extract is generally well tolerated short-term; the most common side effects are loose stools and nausea.

Safety data are limited for long-term use, and the safety data advises against it during pregnancy. There is not enough reliable safety information to use it while breastfeeding.

Fenugreek seed is generally well tolerated in food amounts, but supplement doses may cause abdominal pain, bloating, diarrhea, flatulence, nausea, or rare severe allergic reactions. The safety data advises against medicinal use during pregnancy.

Side effects, ingredient by ingredient Holy Basil Fenugreek Lactobacillus Acidophilus Bacillus Coagulans Saccharomyces Boulardii Lactobacillus Gasseri

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 6 of the 6 matched ingredients can interact with medications — Saccharomyces Boulardii, Fenugreek, Lactobacillus Acidophilus, Holy Basil, Bacillus Coagulans, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 614 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check your medications against anticoagulant and antiplatelet drugs (Moderate risk from fenugreek), antidiabetes drugs (Moderate risk from both holy basil and fenugreek), antibiotics (Moderate risk from three probiotic strains), and if you take warfarin, clopidogrel, phenytoin, metoprolol, theophylline, sildenafil, or pentobarbital, those warrant a careful look too — all Moderate interactions with fenugreek or holy basil. Antifungals may reduce the effectiveness of the yeast in this formula (Minor).

Use the medication checker below to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're looking for digestive support and probiotic strains with some evidence behind them, especially for irritable bowel syndrome or diarrhea. However, you need to be careful if you take blood thinners, diabetes medications, seizure drugs, or certain other prescriptions — check your exact medications with the tool on this page first.

If you're pregnant, breastfeeding, critically ill, or have a weakened immune system, talk with your doctor before starting. A quick conversation with your pharmacist will make sure it's safe for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ancient Probiotics Women's Once Daily, straight from the product label.

Brand Ancient Nutrition
Barcode (UPC) 816401023056
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Jul 23, 2020
DSLD ID 230814
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult Female (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ancient Probiotics Women's Once Daily by Ancient Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
816401023056
IngredientAmount% DV
Lactobacillus plantarum0 NP--
Lactobacillus rhamnosus0 NP--
Lactobacillus acidophilus0 NP--
Bacillus coagulans0 NP--
Saccharomyces boulardii0 NP--
Bifidobacterium animalis lactis0 NP--
Holy Basil Leaf Extract0 NP--
Lactobacillus gasseri0 NP--
Lactobacillus paracasei0 NP--
Women's Herbal Blend421 mg--
Triphala fruit extract0 NP--
Fenugreek seed extract0 NP--
Women's Probiotic Blend166 mg--

Other ingredients: Hypromellose, Rice Fiber, Rice extract Blend

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Ayurveda inspired

Formula

25 Billion CFU At expiration date under recommended storage conditions.

Formulation

Supports: Healthy digestive function Healthy elimination Reduction of occasional diarrhea, constipation, gas and bloating

Color and odor may vary from lot to lot.

FDA Statement of Identity

Whole Food Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Adults take 1 capsule, once per day. Can be taken with or without food.

Storage

Best if refrigerated.

Store in a cool, dry place.

Precautions

Warning: As with any dietary supplement, consult your healthcare practitioner before using this product, especially if you are pregnant, nursing or under medical supervision. If you are currently undergoing HIV treatment, chemotherapy, or allograft therapy, do not use before consulting your physician.

Do not use if safety seal is broken or missing.

Keep out of reach of children.

Notice: Use this product as a food supplement only. Do not use for weight reduction.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ancient Probiotics Women's Once Daily by Ancient Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ancient Probiotics Women's Once Daily label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ancient Probiotics Women's Once Daily by Ancient Nutrition

These are the 11 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Women's Herbal Blend

421 mg per serving

Women's Probiotic Blend

166 mg per serving

Other (inactive) ingredients: Hypromellose, Rice Fiber, Rice extract Blend. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ancient Probiotics Women's Once Daily by Ancient Nutrition Drug Interactions

Want to check YOUR meds against Ancient Probiotics Women's Once Daily?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
614Drugs
409 Moderate 205 Minor

Ingredients driving the most interactions

Fenugreek seed extract 389
Holy Basil Leaf Extract 212
Lactobacillus acidophilus 182
Bacillus coagulans 182
Lactobacillus gasseri 182

Individual Drug Interactions

The ingredients in Ancient Probiotics Women's Once Daily interact with 614 drugs. Click any drug to see the details.

6 of the 11 ingredients in Ancient Probiotics Women's Once Daily interact with drugs. Each result below shows which ingredient is responsible. Fenugreek seed extract Holy Basil Leaf Extract Lactobacillus acidophilus Bacillus coagulans Lactobacillus gasseri Saccharomyces boulardii

Each ingredient & the kinds of drugs it affects

For each ingredient in Ancient Probiotics Women's Once Daily with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Fenugreek seed extract9 drug types · 389 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .

Likelihood Unlikely Evidence B
Antidiabetes Drugs

Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.

Likelihood Probable Evidence B
Clopidogrel (Plavix)

Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.

Likelihood Possible Evidence D
Metoprolol (Toprol)

Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.

Likelihood Probable Evidence B
Phenytoin (Dilantin)

Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Theophylline

Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.

Likelihood Possible Evidence D
Antihypertensive Drugs

Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.

Likelihood Possible Evidence C
Fenugreek seed extract full monograph & interactions

Holy Basil Leaf Extract3 drug types · 212 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal research shows that holy basil seed oil can prolong bleeding time, possibly due to inhibition of platelet aggregation. However, it is not known if this occurs in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies show that taking holy basil can decrease fasting blood glucose and other measures of glycemic control in patients with type 2 diabetes.

Likelihood Possible Evidence B
Pentobarbital (Nembutal)

Theoretically, holy basil seed oil might increase the sedative effects of pentobarbital.
Animal research shows that holy basil seed oil increases pentobarbitone-induced sleeping time. However, it is not known if this occurs in humans or if this applies to other barbiturates or sedatives.

Likelihood Possible Evidence D
Holy Basil Leaf Extract full monograph & interactions

Lactobacillus acidophilus1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus full monograph & interactions

Bacillus coagulans1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
Bacillus coagulans full monograph & interactions

Lactobacillus gasseri1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus gasseri with antibiotic drugs might decrease the effectiveness of L. gasseri.
Lactobacillus gasseri preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. gasseri preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus gasseri full monograph & interactions

Saccharomyces boulardii1 drug type · 40 drugs

Antifungals

Theoretically, taking antifungals with Saccharomyces boulardii might decrease the effectiveness of Saccharomyces boulardii.
S. boulardii is a live yeast. Therefore, simultaneously taking antifungals might kill a significant number of the organisms.

Likelihood Possible Evidence D
Saccharomyces boulardii full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ancient Probiotics Women's Once Daily, from the product label.

Ancient Nutrition

See all Ancient Nutrition products
Name
Ancient Nutrition, LLC
Street Address
2000 Mallory Lane Suite 130-307
City
Franklin
State
TN
ZipCode
37067
Web Address
www.AncientNutrition.com
Pharmacist Counseling Corner

Ancient Probiotics Women's Once Daily by Ancient Nutrition: Common Questions

Does Ancient Probiotics Women's Once Daily by Ancient Nutrition interact with any medications?
Yes. Based on its ingredients, Ancient Probiotics Women's Once Daily has a known interaction with 614 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ancient Probiotics Women's Once Daily contains 11 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Lactobacillus acidophilus is rated possibly safe in pregnancy, but Holy Basil Leaf Extract is possibly unsafe — the safety data advises against it during pregnancy and breastfeeding. Fenugreek is likely unsafe in pregnancy. Since this product contains all three, you should not use it during pregnancy or while breastfeeding without explicit approval from your doctor or midwife.
Will antibiotics ruin this supplement?
Yes — if you take antibiotics at the same time as this product, the antibiotics may kill the live probiotic organisms and make the supplement less effective. Space them out: take your antibiotic and the probiotic at least 2 hours apart, and ask your pharmacist for the best timing for your specific antibiotic.
What are the most common side effects?
Gastrointestinal complaints are the most common — bloating, flatulence, abdominal pain, nausea, or loose stools — but they're uncommon. Holy Basil can also cause loose stools and nausea. Most people tolerate the product well.
Is this safe for someone with a weakened immune system?
No. The product contains live organisms (probiotics and a yeast), and there is a concern they could cause infection in people who are severely ill or immunocompromised, including those with central venous catheters. If your immune system is weak or you're critically ill, talk to your doctor before using this.
Does this product actually work?
It depends on what you're using it for. Lactobacillus acidophilus and Saccharomyces boulardii have possibly effective evidence for irritable bowel syndrome, diarrhea, and some infections. Bacillus coagulans is possibly effective for constipation and IBS. For other uses — like general women's health or the other probiotics — the evidence isn't established in the data we hold.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ancient Probiotics Women's Once Daily label
Go deeper

The Full Monographs Behind Ancient Probiotics Women's Once Daily’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Holy Basil

Interacts with 212 drugs

Holy basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and preliminary. It is generally well tolerat...

Read the full Holy Basil monograph → Herb & supplement monograph

Fenugreek

Interacts with 389 drugs

Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. Some early research is encouraging for blo...

Read the full Fenugreek monograph → Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph → Herb & supplement monograph

Bacillus Coagulans

Interacts with 182 drugs

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...

Read the full Bacillus Coagulans monograph → Herb & supplement monograph

Saccharomyces Boulardii

Interacts with 40 drugs

Saccharomyces boulardii is a beneficial yeast used as a probiotic, with the strongest evidence for preventing and treating certain types of diarrhea, including antibiotic-associated diarrhea...

Read the full Saccharomyces Boulardii monograph → Herb & supplement monograph

Lactobacillus Gasseri

Interacts with 182 drugs

Lactobacillus gasseri is a 'friendly' probiotic bacterium found naturally in the human gut, mouth, and vaginal tract, and in some fermented foods. Early research suggests it may help with di...

Read the full Lactobacillus Gasseri monograph →
Sources

Sources & How We Checked

Ancient Probiotics Women's Once Daily's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 111 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Bacillus Coagulans 20 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
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See these in context on the Bacillus Coagulans monograph →

Saccharomyces Boulardii 26 references
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See these in context on the Saccharomyces Boulardii monograph →

Holy Basil 8 references
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See these in context on the Holy Basil monograph →

Lactobacillus Gasseri 12 references
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See these in context on the Lactobacillus Gasseri monograph →

Fenugreek 30 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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