Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

AnthroPlex Ingredients & Drug Interactions

by InfoWars Life

AnthroPlex label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking AnthroPlex against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

AnthroPlex is a dietary supplement by InfoWars Life with 5 active ingredients. Its ingredients are commonly taken for erectile dysfunction, low libido, fatigue and low energy.Based on those ingredients, 1,219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Horny Goat Weed, Tribulus terrestris, Fulvic powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against AnthroPlex by InfoWars Life

Ask about any prescription or over-the-counter medication and we check it for interactions with AnthroPlex by InfoWars Life — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of AnthroPlex by InfoWars Life

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 5 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (710 mg) without saying how much of each component you get.

AnthroPlex contains five active ingredients. A Proprietary Blend (which lists its components separately) combines Horny Goat Weed, Zinc Orotate, Tribulus terrestris, Tongkat Ali–Longjack (Eurycoma longifolia), and Fulvic powder.

The product also contains two inactive ingredients: organic Gum Acacia and Vegetarian Capsules, which serve as a binder and capsule material.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: support normal hormone balance and vitality in men.
  • We looked for evidence on: Age-related testosterone deficiency, Athletic performance, Erectile dysfunction (ED), Fatigue, Sexual function, Male enhancement — and 1 related terms.
  • The closest evidence on file: Tribulus is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Eurycoma Longifolia is rated "Possibly Ineffective" for Athletic performance.
  • Also on file: Tribulus is rated "Insufficient Reliable Evidence To Rate" for Chronic fatigue syndrome (CFS), Erectile dysfunction (ED).

The evidence base for these ingredients is sparse. Horny Goat Weed has insufficient reliable evidence for sexual dysfunction, osteoporosis, bronchitis, and coronary heart disease.

Zinc is effective for zinc deficiency and likely effective for Wilson disease; it is possibly effective for acne, acrodermatitis enteropathica, age-related macular degeneration, and diabetes. Tribulus is possibly effective for sexual dysfunction but possibly ineffective for athletic performance; evidence is insufficient for benign prostatic hyperplasia.

Tongkat Ali–Longjack is possibly effective for sexual desire but possibly ineffective for athletic performance; evidence is insufficient for back pain, osteoporosis, and diabetes. Fulvic powder lacks sufficient evidence for respiratory tract infections, lead toxicity, atopic dermatitis, fatigue, and allergic rhinitis.

Most of the intended uses of this product lack solid evidence.

The evidence, ingredient by ingredient Horny Goat Weed Tribulus Eurycoma Longifolia Fulvic Acid Zinc

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Horny Goat Weed is generally well tolerated short-term, though quality varies between products. Common side effects include dizziness, dry mouth, nosebleed, thirst, and vomiting; respiratory arrest has been reported rarely.

One case describes a 66-year-old male with heart disease who developed an irregular heartbeat after two weeks, though it's unclear if horny goat weed alone or a combination was responsible. Long-term use has been linked to vomiting, dry mouth, thirst, and nosebleed.

Zinc is well tolerated below 40 mg daily but can cause abdominal cramps, diarrhea, a metallic taste, nausea, and vomiting at higher doses. Long-term high-dose use raises concern for copper deficiency.

Tribulus is often well tolerated but can cause gastrointestinal upset (abdominal pain, cramping, nausea, vomiting, diarrhea, constipation); rare reports include liver and kidney injury, seizures, and painful erection. Tongkat Ali–Longjack may increase testosterone beyond normal, which carries risk of acne, insulin resistance, and liver damage.

Fulvic powder appears well tolerated; common side effects are diarrhea, headache, and sore throat.

Side effects, ingredient by ingredient Horny Goat Weed Tribulus Eurycoma Longifolia Fulvic Acid Zinc

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 5 matched ingredients can interact with medications — Tribulus, Horny Goat Weed, Zinc, Eurycoma Longifolia, Fulvic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 1,220 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take blood pressure drugs (Moderate risk with horny goat weed and tribulus), diabetes medications (Moderate risk with tribulus), blood thinners or antiplatelet drugs (Moderate risk with horny goat weed and fulvic powder), antibiotics including quinolones, tetracyclines, and cephalexin (Moderate risk with zinc), thyroid hormone (Moderate risk with fulvic powder), lithium (Moderate risk with tribulus), or HIV medications like ritonavir or integrase inhibitors (Moderate risk with zinc). The beta-blocker propranolol may be less effective (Moderate risk with Tongkat Ali–Longjack).

Several other drug types are affected by liver enzyme inhibition from horny goat weed and Tongkat Ali–Longjack; the interaction checker below will help identify your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product is marketed for sexual function and athletic performance, but evidence is insufficient or lacking for most of those claims. If you take blood pressure medication, diabetes drugs, blood thinners, antibiotics, thyroid hormone, lithium, or HIV medications, talk with your pharmacist before starting — several ingredients interact with these drug types.

Pregnancy and breastfeeding are not recommended; safety data is not established for any of the active ingredients.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 5 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 21, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about AnthroPlex, straight from the product label.

Brand InfoWars Life
Barcode (UPC) 743724205619
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Oct 21, 2017
DSLD ID 79085
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult Male (18-50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for AnthroPlex by InfoWars Life, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
743724205619
IngredientAmount% DV
Proprietary Blend710 mg--
Horny Goat Weed0 NP--
Zinc Orotate1 mg6%
Tribulus terrestris0 NP--
Tongkat Ali-Longjack0 NP--
Fulvic powder0 NP--

Other ingredients: organic Gum Acacia, Vegetarian Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

AnthroPlex is formulated to support normal hormone balance and boost vitality in men.

Daily foundation for men

Suggested/Recommended/Usage/Directions

Suggested Use: Take one serving (one capsule) in the morning and one serving (one capsule) in the evening with purified water.

Precautions

Warning: Keep out of reach of children.

Consult your healthcare provider if pregnant, nursing or for any additional concerns.

Do not use if seal is broken

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

General Statements

The #1 health product line suggested by Alex Jones

Not tested on animals

Seals/Symbols

GMO free Made in USA Gluten Free 100% Vegan

Formulation

GMO free Gluten free

100% Vegan

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

AnthroPlex by InfoWars Life label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

AnthroPlex label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in AnthroPlex by InfoWars Life

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

710 mg per serving

Zinc Orotate

Interacts with
67 drugs
1 mg per serving

Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but suppleme...

Zinc Orotate monograph & interactions

Other (inactive) ingredients: Organic Gum Acacia, Vegetarian Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

AnthroPlex by InfoWars Life Drug Interactions

Want to check YOUR meds against AnthroPlex?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,219Drugs
1,195 Moderate 24 Minor

Ingredients driving the most interactions

Horny Goat Weed 963
Tribulus terrestris 259
Fulvic powder 257
Tongkat Ali-Longjack 248
Zinc Orotate 67

Individual Drug Interactions

The ingredients in AnthroPlex interact with 1,219 drugs. Click any drug to see the details.

5 of the 5 ingredients in AnthroPlex interact with drugs. Each result below shows which ingredient is responsible. Horny Goat Weed Tribulus terrestris Fulvic powder Tongkat Ali-Longjack Zinc Orotate

Each ingredient & the kinds of drugs it affects

For each ingredient in AnthroPlex with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Horny Goat Weed6 drug types · 963 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, horny goat weed might increase the risk of bleeding.
In vitro research and animal research shows that horny goat weed can inhibit platelet aggregation and thrombus formation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, horny goat weed might increase the risk of hypotension.
Laboratory research suggests that horny goat weed might have hypotensive effects. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP1A2 substrates.
In vitro, horny goat weed leaf extract inhibits CYP1A2. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP2B6 substrates.
In vitro, horny goat weed leaf extract inhibits CYP2B6. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP3A4 substrates.
In vitro, horny goat weed extract inhibits CYP3A4 and suppresses CYP3A4 mRNA expression. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, concomitant use of horny goat weed with estrogens might increase their therapeutic and adverse effects.
In vitro evidence suggests that horny goat weed has estrogenic activity. In clinical research, horny goat weed has been shown to increase blood levels of estrogen in some females.

Likelihood Possible Evidence D
Horny Goat Weed full monograph & interactions

Tribulus terrestris3 drug types · 259 drugs

Antidiabetes Drugs

Taking tribulus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that Tribulus can lower blood glucose levels in adults with type 2 diabetes who are taking antidiabetes medications.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, taking tribulus with antihypertensive drugs might increase the risk of hypotension.
Animal research shows that tribulus can lower blood pressure by inhibiting angiotensin-converting enzyme (ACE). Tribulus has also demonstrated hypotensive effects in pre-hypertensive adults.

Likelihood Possible Evidence D
Lithium

Theoretically, tribulus might increase the levels and clinical effects of lithium.
Tribulus is thought to have diuretic properties. Due to these potential diuretic effects, tribulus might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Tribulus terrestris full monograph & interactions

Fulvic powder3 drug types · 257 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
In vitro evidence shows that fulvic acid, formed from the oxidation and polymerization of protocatechuic acid, can shorten prothrombin time in human plasma, increasing the risk of clot formation.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Animal research shows that fulvic acid stimulates immune function.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, taking fulvic acid with thyroid hormone therapy might interfere with the ability to normalize thyroid function.
Animal research shows that fulvic acid increases the plasma level of thyroid-stimulating hormone (TSH) and decreases the thyroxine (T4):triiodothyronine (T3) ratio.

Likelihood Possible Evidence D
Fulvic powder full monograph & interactions

Tongkat Ali-Longjack5 drug types · 248 drugs

Propranolol (Inderal)

Eurycoma longifolia can reduce the levels and clinical effects of propranolol.
A small clinical study in healthy persons shows that taking a single dose of a water-based Eurycoma longifolia extract 200 mg, in combination with a single dose of propranolol 80 mg, reduces the propranolol area under the curve (AUC) by 29%, reduces the peak concentration by 42%, and increases time to peak concentration by 86% when compared with control. Since the elimination half-life of propranolol did not change, it seems that Eurycoma longifolia alters the kinetics of propranolol by decreasing its absorption in the gut, and not by altering its metabolism. It is not known if separating administration will prevent this interaction.

Likelihood Probable Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Eurycoma longifolia might increase levels CYP1A2 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP1A2 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2A6 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2A6 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Eurycoma longifolia might increase levels of CYP2C19 substrates.
In vitro research suggests that methanolic Eurycoma longifolia root extract weakly inhibits CYP2C19 enzymes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Testosterone

Theoretically, Eurycoma longifolia may further increase levels of testosterone.
A clinical study in aging males with testosterone levels below 300 ng/dL shows that taking a specific water extract of Eurycoma longifolia roots (Physta; Biotropics Malaysia) 100-200 mg daily with breakfast for 12 weeks increases total testosterone levels by 8% to 11% when compared with placebo. It is unclear whether this increase would occur in individuals with normal testosterone levels.

Likelihood Possible Evidence D
Tongkat Ali-Longjack full monograph & interactions

Zinc Orotate10 drug types · 67 drugs

Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Theoretically, zinc might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide should be taken at least 2 hours before or 6 hours after zinc containing products.

Likelihood Probable Evidence D
Cephalexin (Keflex)

Zinc might decrease cephalexin levels by chelating with cephalexin in the gut and preventing its absorption.
A pharmacokinetic study shows that zinc sulfate 250 mg taken concomitantly with cephalexin 500 mg decreases peak levels of cephalexin by 31% and reduces the exposure to cephalexin by 27%. Also, taking zinc sulfate 3 hours before cephalexin decreases peak levels of cephalexin by 11% and reduces the exposure to cephalexin by 18%. By decreasing cephalexin levels, zinc might increase the risk of treatment failure. This effect does not occur when zinc is taken 3 hours after the cephalexin dose. To avoid an interaction, advise patients take zinc sulfate 3 hours after taking cephalexin.

Likelihood Probable Evidence B
Cisplatin (Platinol-Aq)

Theoretically, zinc might interfere with the therapeutic effects of cisplatin.
Animal research suggests that zinc stimulates tumor cell production of the protein metallothionein, which binds and inactivates cisplatin. It is not known whether zinc supplements or high dietary zinc intake can cause clinically significant interference with cisplatin therapy. Cisplatin might also increase zinc excretion.

Likelihood Possible Evidence D
Integrase Inhibitors

Theoretically, taking zinc along with integrase inhibitors might decrease the levels and clinical effects of these drugs.
Zinc is a divalent cation. Pharmacokinetic studies have shown that other divalent cations such as calcium and iron can decrease blood levels of the integrase inhibitor dolutegravir through chelation.

Likelihood Possible Evidence D
Penicillamine (Cuprimine, Depen)

Zinc might reduce the levels and clinical effects of penicillamine.
By forming an insoluble complex with penicillamine, zinc interferes with penicillamine absorption and activity. Zinc supplements reduce the efficacy of low-dose penicillamine (0.5-1 gram/day), but do not seem to affect higher doses (1-2.75 gram/day), provided dosing times are separated. Advise patients to take zinc and penicillamine at least 2 hours apart.

Likelihood Probable Evidence B
Quinolone Antibiotics

Zinc can decrease the levels and clinical effects of quinolones antibiotics.
Quinolones form complexes with zinc in the gastrointestinal tract, reducing absorption of both the quinolone and zinc if taken at the same time. Advise patients to take these drugs at least 2 hours before, or 4-6 hours after, zinc supplements.

Likelihood Probable Evidence B
Ritonavir (Norvir)

Zinc modestly reduces levels of ritonavir.
Clinical research shows that zinc might reduce serum ritonavir levels by chelating with ritonavir in the gut and preventing its absorption. In patients with HIV, ritonavir is taken with atazanavir to prevent the metabolism and increase the effects of atazanavir. A pharmacokinetic study shows that, in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate (Solvazinc tablets) 125 mg as a single dose or as multiple daily doses for 2 weeks reduces plasma levels of ritonavir by about 16%. However, atazanavir levels still remains high enough to prevent HIV virus replication. Therefore, the decrease in ritonavir levels is not likely to be clinically significant.

Likelihood Probable Evidence B
Tetracycline Antibiotics

Zinc might reduce levels of tetracycline antibiotics.
Tetracyclines form complexes with zinc in the gastrointestinal tract, which can reduce absorption of both the tetracycline and zinc when taken at the same time. Taking zinc sulfate 200 mg with tetracycline reduces absorption of the antibiotic by 30% to 40%. Demeclocycline and minocycline cause a similar interaction. However, doxycycline does not seem to interact significantly with zinc. Advise patients to take tetracyclines at least 2 hours before, or 4-6 hours after, zinc supplements to avoid any interactions.

Likelihood Probable Evidence B
Amiloride (Midamor)

Amiloride can modestly reduce zinc excretion and increase zinc levels.
Clinical research shows that amiloride can reduce urinary zinc excretion, especially at doses of 10 mg per day or more. This zinc-sparing effect can help to counteract zinc losses caused by thiazide diuretics, but it is unlikely to cause zinc toxicity at usual amiloride doses. The other potassium-sparing diuretics, spironolactone (Aldactone) and triamterene (Dyrenium), do not seem to have a zinc-sparing effect.

Likelihood Probable Evidence B
Atazanavir (Reyataz)

Zinc modestly reduces levels of atazanavir, although this effect does not seem to be clinically significant.
Clinical research shows that zinc might decrease serum atazanavir levels by chelating with atazanavir in the gut and preventing its absorption. Although a single dose of zinc sulfate (Solvazinc tablets) 125 mg orally does not affect atazanavir concentrations in patients being treated with atazanavir/ritonavir, co-administration of zinc sulfate 125 mg daily for 2 weeks reduces plasma levels of atazanavir by about 22% in these patients. However, despite this decrease, atazanavir levels still remain at high enough concentrations for the prevention of HIV virus replication.

Likelihood Probable Evidence B
Zinc Orotate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for AnthroPlex, from the product label.

InfoWars Life

See all InfoWars Life products
Name
InfoWars Life
Phone Number
1-888-253-3139
Web Address
www.infowarslife.com
Pharmacist Counseling Corner

AnthroPlex by InfoWars Life: Common Questions

Does AnthroPlex by InfoWars Life interact with any medications?
Yes. Based on its ingredients, AnthroPlex has a known interaction with 1,219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
AnthroPlex contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take if I'm pregnant or breastfeeding?
No. Horny Goat Weed is rated possibly unsafe in pregnancy. Tribulus and Fulvic powder should be avoided during pregnancy and breastfeeding because there isn't enough safety information. Tongkat Ali–Longjack carries potential hormonal effects and lacks safety data in pregnancy and breastfeeding. Talk with your doctor or pharmacist before considering this product if you are pregnant, planning pregnancy, or breastfeeding.
What is Horny Goat Weed used for in this product?
Horny Goat Weed is traditionally used for sexual function, but the evidence is insufficient to reliably confirm it works. It's also been studied for osteoporosis, bronchitis, and heart disease, but again without solid proof of benefit.
Is the zinc in this product enough to treat a deficiency?
The product label doesn't state the zinc dose, so you'd need to check the supplement facts panel or ask the manufacturer. Zinc is effective for treating deficiency, but the amount in a multi-ingredient supplement like this may be too small for that purpose.
What does Fulvic powder do?
Fulvic powder is claimed to support immune and general health, but we hold insufficient evidence for respiratory infections, lead toxicity, eczema, fatigue, and allergies. No solid proof supports its use for these conditions yet.
Can Tongkat Ali–Longjack increase my testosterone?
Clinical studies show it may modestly increase testosterone in aging males with low levels. If your testosterone goes above normal, there's risk of acne, insulin resistance, and liver damage, so talk with your doctor before starting if you have concerns about your hormones.
What are the most common side effects?
Horny Goat Weed can cause dizziness, dry mouth, nosebleed, thirst, and vomiting. Zinc may cause abdominal cramps, diarrhea, a metallic taste, nausea, and vomiting at higher doses. Tribulus can cause nausea, vomiting, diarrhea, and abdominal pain. Fulvic powder commonly causes diarrhea, headache, and sore throat.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

AnthroPlex label
Go deeper

The Full Monographs Behind AnthroPlex’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Horny Goat Weed

Interacts with 963 drugs

Horny goat weed (Epimedium) is a traditional Chinese herb most often marketed for low libido and erectile problems, but solid human evidence for these uses is lacking. While short-term use s...

Read the full Horny Goat Weed monograph → Herb & supplement monograph

Tribulus

Interacts with 259 drugs

Tribulus is a plant supplement most often marketed to boost libido, testosterone, and athletic performance, but the human evidence behind these claims is weak and inconsistent. It is general...

Read the full Tribulus monograph → Herb & supplement monograph

Eurycoma Longifolia

Interacts with 248 drugs

Eurycoma longifolia (tongkat ali) is a Southeast Asian herb most popular for supporting testosterone, libido, and male fertility, with some small human studies suggesting possible benefits....

Read the full Eurycoma Longifolia monograph → Herb & supplement monograph

Fulvic Acid

Interacts with 257 drugs

Fulvic acid is a natural compound formed when plants and microbes break down in soil, and it is sold as a supplement for energy, gut, and overall wellness. Human research is very limited, so...

Read the full Fulvic Acid monograph → Herb & supplement monograph

Zinc

Interacts with 67 drugs

Zinc is an essential mineral that your body needs for immune function, wound healing, taste, and smell. Most people get enough from food, but supplements can help correct or prevent a defici...

Read the full Zinc monograph →
Sources

Sources & How We Checked

AnthroPlex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 116 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Horny Goat Weed 11 references
  1. Cirigliano MD, Szapary PO. Horny goat weed for erectile dysfunction. Alt Med Alert 2001;4:19-22.
  2. Partin JF, Pushkin YR. Tachyarrhythmia and hypomania with horny goat weed. Psychosomatics 2004;45:536-7. PubMed
  3. De Naeyer A, Pocock V, Milligan S, De Keukeleire D. Estrogenic activity of a polyphenolic extract of the leaves of Epimedium brevicornum. Fitoterapia 2005;76:35-40. PubMed
  4. Zhang CZ, Wang SX, Zhang Y, et al. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms. J Ethnopharmacol 2005;98:295-300. PubMed
  5. Yap SP, Shen P, Li J, et al. Molecular and pharmacodynamic properties of estrogenic extracts from the traditional Chinese medicinal herb, Epimedium. J Ethnopharmacol 2007;113:218-24. PubMed
  6. Yan, F. F., Liu, Y., Liu, Y. F., and Zhao, Y. X. Herba Epimedii water extract elevates estrogen level and improves lipid metabolism in postmenopausal women. Phytother.Res. 2008;22(9):1224-1228. PubMed
  7. Ramanathan VS, Mitropoulos E, Shlopov B, et al. An Enzyte'ing' case of acute hepatitis. J Clin Gastroenterol 2011;45(9):834-5. PubMed
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Eurycoma Longifolia 4 references
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Fulvic Acid 3 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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