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Dietary supplement

Apple Cider Vinegar 1500 mg Ingredients & Drug Interactions

by Webber Naturals

Apple Cider Vinegar 1500 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Apple Cider Vinegar 1500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Apple Cider Vinegar 1500 mg is a dietary supplement by Webber Naturals with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, weight management, digestive upset.Based on those ingredients, 162 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Apple Cider Vinegar. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Apple Cider Vinegar 1500 mg by Webber Naturals

Ask about any prescription or over-the-counter medication and we check it for interactions with Apple Cider Vinegar 1500 mg by Webber Naturals — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Apple Cider Vinegar 1500 mg by Webber Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: apple cider vinegar at 1500 mg per capsule. The inactive ingredients are gelatin, purified water, and magnesium stearate — all standard capsule fillers and binders.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Apple Cider Vinegar product and its label doesn't state a use — see Apple Cider Vinegar's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for apple cider vinegar is not established in the data we hold. We list six uses — acne, athletic performance, cognitive function, dental plaque, depression, and atopic dermatitis (eczema) — and for all of them, the scientific evidence is insufficient to rate whether it works.

If you're considering this for a specific condition, talk it over with your doctor or pharmacist about what the current research actually shows.

The evidence, ingredient by ingredient Apple Cider Vinegar

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

In food amounts, apple cider vinegar is generally well tolerated. Short-term medicinal use seems to be well tolerated too.

However, the safety data for larger supplement doses taken long-term is limited, and there's real concern: a documented case showed that chronic heavy use (250 mL per day for 6 years) led to low potassium, high renin levels, and osteoporosis. Topically, it can cause chemical burns and skin irritation.

The safety data on large or unpasteurized amounts is thin, so those should be cleared with your doctor first.

Side effects, ingredient by ingredient Apple Cider Vinegar

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Apple Cider Vinegar.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications.
  • For scale: 162 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this if you use a diuretic (water pill), digoxin (a heart medication), insulin, or any antidiabetes drug. All of these carry documented Moderate or Minor interactions, and the biggest concern is low potassium — especially with diuretics and digoxin.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is fine in small food amounts, but if you're taking a diuretic, digoxin, insulin, or an antidiabetes drug, you'll need to check with your doctor or pharmacist before starting it. Long-term heavy use carries a real risk of dropping your potassium too low.

For its marketed uses, the evidence we have is not strong enough to say whether it actually works.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Apple Cider Vinegar 1500 mg, straight from the product label.

Brand Webber Naturals
Barcode (UPC) 810050820028
Net contents 240 Capsule(s)
Market status On market
Date entered into DSLD Mar 22, 2024
DSLD ID 310120
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Apple Cider Vinegar 1500 mg by Webber Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
80
UPC/BARCODE
810050820028
IngredientAmount% DV
Calories5 Calorie(s)--
Total Carbohydrate1 Gram(s)1%
Apple Cider Vinegar1500 mg--

Other ingredients: Gelatin, Water, Purified, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Why choose Webber Naturals? Webber Naturals' guarantee starts with our ingredient sourcing and continues through each stage of development, formulation, and manufacturing. We safeguard your trust by making sure that every raw material and finished product is tested to the highest international standards for quality, purity, and efficacy. Made with a commitment to excellence and sustainability - from us to you without compromise.

Assured quality since 1948

Please recycle container.

Suggested/Recommended/Usage/Directions

Suggested Use (Adults): 3 capsules daily, preferably with plenty of water, or as directed by a physician.

Precautions

Caution: Consult physician before use, especially if pregnant or nursing, taking medication or have a medical condition.

Keep out of the reach of children.

Formula

How does apple cider vinegar work? Fermented naturally with the "mother", the culture of beneficial bacteria that transforms apple cider into vinegar. Each easy-to-swallow capsule provides 500mg, the equivalent of 1 teaspoon, of sugar-free apple cider vinegar (ACV), making it a convenient way to enjoy the benefits of ACV, without having to drink the liquid, and a healthier option to many gummies. ACV has been used traditionally to promote healthy digestion and support overall good health.

Apple Cider Vinegar 1500mg per serving Naturally with the "mother"

Storage

For product freshness protect from heat and humidity. Sealed for safety and freshness.

Formulation

Free of artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, salt, tree nuts, or GMOs.

Non-GMO Gluten free

Product of Canada

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Apple Cider Vinegar 1500 mg by Webber Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Apple Cider Vinegar 1500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Apple Cider Vinegar 1500 mg by Webber Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container80 Amounts shown are per serving.

Apple Cider Vinegar

Interacts with
162 drugs
1500 mg per serving Form: Malus pumila

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of...

Apple Cider Vinegar monograph & interactions

Other (inactive) ingredients: Gelatin, Water, Purified, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Apple Cider Vinegar 1500 mg by Webber Naturals Drug Interactions

Want to check YOUR meds against Apple Cider Vinegar 1500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
162Drugs
89 Moderate 73 Minor

Ingredients driving the most interactions

Apple Cider Vinegar 162

Individual Drug Interactions

The ingredients in Apple Cider Vinegar 1500 mg interact with 162 drugs. Click any drug to see the details.

1 of the 1 ingredient in Apple Cider Vinegar 1500 mg interact with drugs. Each result below shows which ingredient is responsible. Apple Cider Vinegar

Each ingredient & the kinds of drugs it affects

For each ingredient in Apple Cider Vinegar 1500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Apple Cider Vinegar4 drug types · 162 drugs

Digoxin (Lanoxin)

Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.

Likelihood Possible Evidence D
Insulin

Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.

Likelihood Possible Evidence B
Apple Cider Vinegar full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Apple Cider Vinegar 1500 mg, from the product label.

Webber Naturals

See all Webber Naturals products
Name
WN Pharmaceuticals Inc.
City
Monroe
State
WA
ZipCode
98272
Phone Number
1-800-430-7898
Web Address
webbernaturals.com
Pharmacist Counseling Corner

Apple Cider Vinegar 1500 mg by Webber Naturals: Common Questions

Does Apple Cider Vinegar 1500 mg by Webber Naturals interact with any medications?
Yes. Based on its ingredients, Apple Cider Vinegar 1500 mg has a known interaction with 162 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Apple Cider Vinegar 1500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What actually is apple cider vinegar, and what is it supposed to do?
Apple cider vinegar is a fermented apple product. This product markets it for several uses — acne, athletic performance, cognitive function, dental plaque, depression, and eczema — but the scientific evidence for any of these is not established yet.
Is it safe to take apple cider vinegar long-term?
The safety data for supplement doses taken long-term is limited. One documented case showed that taking 250 mL of apple cider vinegar every day for 6 years caused dangerous drops in potassium, high renin levels, and bone loss. In normal food amounts, it's well tolerated, but large medicinal doses should be cleared with your doctor first.
Can I take this if I'm on a water pill (diuretic)?
No, not without talking to your doctor first. Both diuretics and apple cider vinegar can lower potassium, and together they raise the risk of potassium dropping dangerously low. Your doctor or pharmacist needs to weigh whether it's safe for your situation.
What are the side effects?
In food amounts, it's well tolerated. In larger doses taken long-term, rare but serious side effects include low potassium, high renin levels, and osteoporosis. If you use it topically, it can cause chemical burns and skin irritation.
Can I take this if I'm on digoxin (Lanoxin) for my heart?
You'll need to check with your doctor or pharmacist before you do. Apple cider vinegar can lower potassium, and low potassium increases the risk of toxicity with digoxin. Your doctor needs to know you're considering it.
Can I use this if I have diabetes or take insulin?
Check with your doctor or pharmacist first. Apple cider vinegar might lower blood sugar, and if you're already on insulin or another diabetes drug, it could push your blood sugar too low. Your prescriber needs to assess whether it's right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Apple Cider Vinegar 1500 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Apple Cider Vinegar 1500 mg label
Go deeper

The Full Monographs Behind Apple Cider Vinegar 1500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Apple Cider Vinegar

Interacts with 162 drugs

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of these uses is limited and mixed, and the...

Read the full Apple Cider Vinegar monograph →
Sources

Sources & How We Checked

Apple Cider Vinegar 1500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Apple Cider Vinegar 11 references
  1. Lhotta K, Hofle G, Gasser R, Finkenstedt G. Hypokalemia, hyperreninemia, and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80:242-3. PubMed
  2. Hill LL, Woodruff LH, Foote JC, Barreto-Alcoba M. Esophageal injury by apple cider vinegar tablets and subsequent evaluation of products. J Am Diet Assoc 2005;105:1141-4. PubMed
  3. Hlebowicz J, Darwiche G, Björgell O, Almér LO. Effect of apple cider vinegar on delayed gastric emptying in patients with type 1 diabetes mellitus: a pilot study. BMC Gastroenterol 2007;7:46. PubMed
  4. Johnston CS, Kim CM, Buller AJ. Vinegar improves insulin sensitivity to a high-carbohydrate meal in subjects with insulin resistance or type 2 diabetes. Diabetes Care 2004;27:281-2. PubMed
  5. Lhotta, K., Hofle, G., Gasser, R., and Finkenstedt, G. Hypokalemia, hyperreninemia and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80(2):242-243. PubMed
  6. Bunick CG, Lott JP, Warren CB, et al. Chemical burn from topical apple cider vinegar. J Am Acad Dermatol 2012;67(4):e143-4. PubMed
  7. Feldstein S, Afshar M, Krakowski AC. Chemical Burn from Vinegar Following an Internet-based Protocol for Self-removal of Nevi. J Clin Aesthet Dermatol. 2015 Jun;8(6):50.
  8. Luu LA, Flowers RH, Kellams AL, et al. Apple cider vinegar soaks [0.5%] as a treatment for atopic dermatitis do not improve skin barrier integrity. Pediatr Dermatol. 2019;36(5):634-639. PubMed
  9. Hadi A, Pourmasoumi M, Najafgholizadeh A, Clark CCT, Esmaillzadeh A. The effect of apple cider vinegar on lipid profiles and glycemic parameters: a systematic review and meta-analysis of randomized clinical trials. BMC Complement Med Ther 2021;21(1):179. PubMed
  10. Feise NK, Johnston CS. Commercial vinegar tablets do not display the same physiological benefits for managing postprandial glucose concentrations as liquid vinegar. J Nutr Metab 2020;2020:9098739. PubMed
  11. Gheflati A, Bashiri R, Ghadiri-Anari A, Reza JZ, Kord MT, Nadjarzadeh A. The effect of apple vinegar consumption on glycemic indices, blood pressure, oxidative stress, and homocysteine in patients with type 2 diabetes and dyslipidemia: A randomized contro

See these in context on the Apple Cider Vinegar monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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