Interactions on record — worth a quick check against your medications. Based on 2 of 5 ingredients. Check your meds →
Dietary supplement

Arginol Fusion Ingredients & Drug Interactions

by Dr. LaMar's Products

Arginol Fusion label
See full label image
Powder Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Arginol Fusion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Arginol Fusion is a dietary supplement by Dr. LaMar's Products with 5 active ingredients. Its ingredients are commonly taken for bone health and osteoporosis, correcting vitamin d deficiency, immune system support.Based on those ingredients, 885 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Vitamin D, Stevia leaf extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Arginol Fusion by Dr. LaMar's Products

Ask about any prescription or over-the-counter medication and we check it for interactions with Arginol Fusion by Dr. LaMar's Products — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Arginol Fusion by Dr. LaMar's Products

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Arginol Fusion contains 4 active ingredients. Vitamin D supports bone health and calcium metabolism and is used to treat conditions like rickets, osteomalacia, and hypoparathyroidism.

Stevia leaf extract is a natural sweetener. The product also includes arginine and citrulline, amino acids involved in various body functions, though we hold no interaction data for either of those two.

The powder form also contains several inactive ingredients—citric acid, potassium bicarbonate, sodium bicarbonate, calcium carbonate, fructose, and wild berry flavoring—which serve as fillers, buffers, and flavorings.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: energy stamina circulatory health exercise performance.
  • We looked for evidence on: Athletic performance, Cardiovascular disease (CVD), Exercise-induced muscle damage, Heart failure, Hypertension, Muscle strength — and 4 related terms.
  • The strongest evidence on file: Vitamin D is rated "Possibly Effective" for Heart failure (Natural Medicines).
  • Also on file: Vitamin D is rated "Possibly Ineffective" for Cardiovascular disease (CVD).
  • Also on file: Stevia is rated "Insufficient Reliable Evidence To Rate" for Hypertension.

Vitamin D in this product is effective for familial hypophosphatemia, osteomalacia (soft bones from vitamin D deficiency), renal osteodystrophy (bone disease from kidney failure), rickets, and hypoparathyroidism (low parathyroid hormone). For stevia leaf extract, the evidence isn't established in our data.

The product includes stevia at a dose we cannot fully assess for diabetes, hypertension, or weight management—the data shows insufficient reliable evidence to rate it for any of those uses.

The evidence, ingredient by ingredient Vitamin D Stevia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin D is generally well tolerated at recommended doses, but very high doses over time can cause toxicity marked by high blood calcium levels (hypercalcemia), and in rare cases kidney problems and anemia. Symptoms of toxicity include weak bones, reduced growth in children, eye inflammation, and light sensitivity.

At recommended doses vitamin D is often used during pregnancy and is generally acceptable while breastfeeding, though you should use it only under your doctor's guidance. Stevia appears well tolerated, though the whole-leaf supplement form (rather than purified stevia in food) lacks robust safety data.

The most common side effects are abdominal bloating, dizziness, headache, muscle pain, nausea, and numbness—most resolve after the first week. Allergic reactions are rare but possible.

Safety data for stevia in pregnancy and lactation are not on file for this product; discuss with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Vitamin D Stevia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Stevia, Vitamin D.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications; lithium.
  • For scale: 886 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Arginol Fusion, double-check any thiazide diuretics, verapamil, diltiazem, or digoxin you're on, as vitamin D at high doses could affect blood calcium levels and your heart rhythm. Also flag lithium, atorvastatin, aluminum-containing products, and calcipotriene.

If you take blood pressure or diabetes medication, let your pharmacist know you're considering this product—stevia may lower blood pressure or blood sugar. We could not check the interaction data for arginine or citrulline.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take a thiazide diuretic, heart rhythm medication, digoxin, cholesterol medication, or lithium, talk with your pharmacist before starting Arginol Fusion. The same goes if you're on blood pressure or diabetes medication—stevia could theoretically amplify their effects.

Anyone using high-dose vitamin D or calcipotriene should check with their doctor before adding this product.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 31, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Arginol Fusion, straight from the product label.

Brand Dr. LaMar's Products
Net contents 16 Ounce(s); 453.59 Gram(s)
Market status On market
Date entered into DSLD Aug 31, 2018
DSLD ID 180265
Product type Botanical With Nutrients
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Arginol Fusion by Dr. LaMar's Products, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Scoop(s)
Maximum serving Sizes:
2 Scoop(s)
Servings per container
30
IngredientAmount% DV
Calories16 Calorie(s)--
Total Carbohydrates4 Gram(s)4%
Sugar2.4 Gram(s)--
Vitamin D400 IU100%
Stevia leaf extract50 mg--
Arginine5000 mg--
Citrulline500 mg--

Other ingredients: Citric Acid, Potassium Bicarbonate, Sodium Bicarbonate, Calcium Carbonate, Fructose, Wild Berry flavoring

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

High Energy Formula Boost energy and stamina Support circulatory health Improve exercise performance Boost immunity Cleanse harmful toxins Enhance sexual function Reduce muscle fatigue and promote muscle growth Great taste

L-Arginine is considered an essential, non-essential and semi-essential amino acid and is an important ingredient in the production of Nitric Oxide and Human Growth Hormone. It also helps to make important compounds in the body such as creatine, L-Glutamine, and L-Proline. It provides optimal circulatory health through increased blood flow and enhances sexual function.

Before taking this product, pause for a moment and "Give God the Glory For Your Health". Thank Him for what you want the nutrients to do for you and "Feel The Difference".

"A Natural Cardiovascular Anti-Aging Product"

Contents packaged by weight, not volume. Some settling will occur.

Formula

Arginine is believed to play a beneficial role in reducing circulatory related challenges and reducing inflammation related to cardiovascular diseases.

Formulation

Arginine Fusion is a great-tasting, pH balanced, sugar-free drink designed to provide all the key nutrients to stimulate circulation, support cellular metabolism, growth, and healing.

FDA Disclaimer Statement

Disclaimer: These statements have not been evaluated by the Food and Drug Administration. These statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease.

Precautions

Consult your physician before taking this product.

Caution: Keep away from children. Not intended for use under the age of 18.

L-Arginine is a vascular dilator.

Consult your healthcare provider if you have a history of heart disease, heart attack or stroke, are pregnant or lactating, diagnosed with herpes virus, have pre-existing conditions or taking prescribed medications, implementing any new diet or exercise program.

Suggested/Recommended/Usage/Directions

Directions: Add 1 scoop into 8 ounces of High Energy Water. Stir or blend until completely dissolved. Take 1/2 hour before meals or exercising. May be taken at bedtime. Take 1 or 2 servings daily or as recommended by your health care professional.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Arginol Fusion by Dr. LaMar's Products label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Arginol Fusion label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Arginol Fusion by Dr. LaMar's Products

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Scoop(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

2.4 Gram(s) per serving

Vitamin D

Interacts with
715 drugs
400 IU per serving Form: Cholecalciferol

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people,...

Vitamin D monograph & interactions

Stevia leaf extract

Interacts with
259 drugs
50 mg per serving

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regu...

Stevia leaf extract monograph & interactions

Arginine

5000 mg per serving

Citrulline

500 mg per serving

Other (inactive) ingredients: Citric Acid, Potassium Bicarbonate, Sodium Bicarbonate, Calcium Carbonate, Fructose, Wild Berry flavoring. These complete the product’s ingredient list but are not active constituents.

Interaction report

Arginol Fusion by Dr. LaMar's Products Drug Interactions

Want to check YOUR meds against Arginol Fusion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
885Drugs
81 Moderate 804 Minor

Ingredients driving the most interactions

Vitamin D 715
Stevia leaf extract 259

Individual Drug Interactions

The ingredients in Arginol Fusion interact with 885 drugs. Click any drug to see the details.

2 of the 5 ingredients in Arginol Fusion interact with drugs. Each result below shows which ingredient is responsible. Vitamin D Stevia leaf extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Arginol Fusion with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin D8 drug types · 715 drugs

Aluminum

Vitamin D might increase aluminum absorption and toxicity, but this has only been reported in people with renal failure.
The protein that transports calcium across the intestinal wall can also bind and transport aluminum. This protein is stimulated by vitamin D, which may therefore increase aluminum absorption. This mechanism may contribute to increased aluminum levels and toxicity in people with renal failure, when they take vitamin D and aluminum-containing phosphate binders chronically.

Likelihood Probable Evidence B
Atorvastatin (Lipitor)

Vitamin D might reduce absorption of atorvastatin.
A small, low-quality clinical study shows that taking vitamin D reduces levels of atorvastatin and its active metabolites by up to 55%. However, while atorvastatin levels decreased, total cholesterol, low-density lipoprotein (LDL) cholesterol, and high-density lipoprotein (HDL) cholesterol levels did not substantially change. Atorvastatin is metabolized in the gut by CYP3A4 enzymes, and researchers theorized that vitamin D might induce CYP3A4, causing reduced levels of atorvastatin. However, this proposed mechanism was not specifically studied.

Likelihood Probable Evidence B
Calcipotriene (Dovonex)

Taking calcipotriene with vitamin D increases the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with vitamin D supplements might increase the risk of hypercalcemia.

Likelihood Probable Evidence D
Digoxin (Lanoxin)

Theoretically, hypercalcemia induced by high-dose vitamin D can increase the risk of arrhythmia from digoxin.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and digoxin concurrently.

Likelihood Possible Evidence D
Diltiazem (Cardizem, Others)

Theoretically, hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of diltiazem for arrhythmia.
High doses of vitamin D can cause hypercalcemia. Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically this could also occur with diltiazem. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and diltiazem concurrently.

Likelihood Probable Evidence B
Thiazide Diuretics

Theoretically, taking thiazide diuretics and high-dose vitamin D can increase the risk of hypercalcemia.
Thiazide diuretics decrease urinary calcium excretion, which could lead to hypercalcemia if vitamin D supplements are taken concurrently. This has been reported in people being treated with vitamin D for hypoparathyroidism, and also in elderly people with normal parathyroid function who were taking a thiazide, vitamin D, and calcium-containing antacids daily.

Likelihood Probable Evidence D
Verapamil (Calan, Others)

Hypercalcemia induced by high-dose vitamin D can reduce the therapeutic effects of verapamil for arrhythmia.
Hypercalcemia due to high doses of vitamin D can reduce the effectiveness of verapamil in atrial fibrillation. Avoid vitamin D doses above the tolerable upper intake level (4000 IU daily for adults) and monitor serum calcium levels in people taking vitamin D and verapamil concurrently.

Likelihood Probable Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Vitamin D might induce CYP3A4 enzymes and reduce the bioavailability of CYP3A4 substrates.
There is some concern that vitamin D might induce CYP3A4. In vitro research suggests that vitamin D induces CYP3A4 transcription. Additionally, observational research has found that increased UV light exposure and serum vitamin D levels are associated with decreased serum levels of CYP3A4 substrates such as tacrolimus and sirolimus, while no association between UV light exposure or vitamin D levels and levels of mycophenolic acid, a non-CYP3A4 substrate, was found. A small, low-quality clinical study shows that taking vitamin D reduces levels of the CYP3A4 substrate atorvastatin and its active metabolites by up to 55%; however, the clinical effects of atorvastatin were not reduced. While researchers theorized that vitamin D might induce CYP3A4, this proposed mechanism was not specifically studied.

Likelihood Possible Evidence D
Vitamin D full monograph & interactions

Stevia leaf extract3 drug types · 259 drugs

Lithium

Theoretically, stevia might decrease clearance and increase levels of lithium.
Animal research suggests that stevia extracts might have diuretic activity. Theoretically, increased reabsorption of lithium along with sodium might reduce excretion and increase levels of lithium.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, stevia might increase the risk for hypoglycemia when combined with antidiabetes drugs.
Preliminary clinical research in patients with type 2 diabetes suggests that taking a single dose of stevia extract 1000 mg reduces postprandial blood glucose levels when taken with a meal. However, other clinical research in patients with type 1 or type 2 diabetes suggests that taking stevioside 250 mg three times daily does not significantly affect blood glucose levels or glycated hemoglobin (HbA1C) after three months of treatment.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining stevia or stevia constituents with antihypertensive agents might increase the risk of hypotension.
Stevia extract and stevioside might lower blood pressure in patients with hypertension. However, other clinical research suggests that stevioside does not significantly lower blood pressure in patients with hypertension.

Likelihood Possible Evidence D
Stevia leaf extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Arginol Fusion, from the product label.

Dr. LaMar's Products

See all Dr. LaMar's Products products
Name
Dr. LaMar's Products Co., Inc.
City
Emporia
State
KS
ZipCode
66801
Phone Number
800-941-2889
Web Address
www.drlamarsproducts.com
Pharmacist Counseling Corner

Arginol Fusion by Dr. LaMar's Products: Common Questions

Does Arginol Fusion by Dr. LaMar's Products interact with any medications?
Yes. Based on its ingredients, Arginol Fusion has a known interaction with 885 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Arginol Fusion contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is the vitamin D in this product safe for pregnancy?
At recommended doses, vitamin D is often used during pregnancy and is considered likely safe, but use it only under your doctor's guidance. High doses carry a risk, so stick with your doctor's recommendation for the right amount for you.
Can I take this if I'm breastfeeding?
Vitamin D is generally considered acceptable at recommended doses while breastfeeding, but check with your doctor before taking higher amounts. We don't have safety data on file for stevia during lactation, so discuss that ingredient with your pharmacist for personalized advice.
What are the side effects of stevia in this product?
Most people tolerate stevia well. The most common side effects are abdominal bloating, dizziness, headache, muscle pain, nausea, and numbness, and these usually resolve after the first week. Allergic reactions are rare.
Does this product actually work for what it claims?
Vitamin D in Arginol Fusion is effective for rickets, osteomalacia, renal osteodystrophy, hypoparathyroidism, and familial hypophosphatemia. For stevia's purported effects on diabetes, blood pressure, or weight, the evidence in our data is insufficient to rate it, so those claims are unproven.
Why can't you check arginine and citrulline for interactions?
We don't hold interaction data for arginine or citrulline in our database, so we can't assess whether they interact with your medications. That doesn't mean they're safe with everything—just that we can't verify it. Ask your pharmacist to check those two ingredients against your prescriptions.
Is this safe at any dose, or just recommended amounts?
Vitamin D is safe at recommended doses, but very high doses taken long-term can cause toxicity. High-dose stevia supplements also lack robust safety data, whereas small amounts of purified stevia in food are well established as safe. Stick with the label dose and talk to your doctor if you're thinking of taking more.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Arginol Fusion label
Go deeper

The Full Monographs Behind Arginol Fusion’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin D

Interacts with 715 drugs

Vitamin D is a fat-soluble vitamin that helps your body absorb calcium and is important for healthy bones, muscles, and immune function. Many people, especially those with low sun exposure,...

Read the full Vitamin D monograph → Herb & supplement monograph

Stevia

Interacts with 259 drugs

Stevia is a plant-based, calorie-free sweetener that is widely used as a sugar alternative and is considered safe in normal food amounts by major regulators. Purified stevia extracts have a...

Read the full Stevia monograph →
Sources

Sources & How We Checked

Arginol Fusion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 36 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin D 26 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Tatro DS, ed. Drug Interactions Facts. Facts and Comparisons Inc., St. Louis, MO. 1999.
  3. Koutkia P, Chen TC, Holick MF. Vitamin D intoxication associated with an over-the-counter supplement. N Engl J Med 2001;345:66-7. PubMed
  4. Bar-Or D, Yoel G. Calcium and calciferol antagonize effect of verapamil in atrial fibrillation. Br Med J 1981;282:1585-6.
  5. Demontis R, Leflon A, Fournier A, et al. 1 alpha(OH) vitamin D3 increases plasma aluminum in hemodialyzed patients taking AI(OH)3. Clin Nephrol 1986;26:146-9.
  6. Crowe M, Wollner L, Griffiths RA. Hypercalcemia following vitamin D and thiazide therapy in the elderly. Practitioner 1984;228:312-3.
  7. Parfitt AM. Thiazide-induced hypercalcemia in vitamin D-treated hypoparathyroidism. Ann Intern Med 1972;77:557-63. PubMed
  8. Thiazide diuretics and the risk of osteoporosis. Pharmacist's Letter/Prescriber's Letter 2003;19(11):191105.
  9. Moon J. The role of vitamin D in toxic metal absorption. J Am Coll Nutr 1994;13:559-64.
  10. Demontis R, Reissi D, Noel C, et al. Indirect clinical evidence that 1alphaOH vitamin D<SUB>3</SUB> increases the intestinal absorption of aluminum. Clin Nephrol 1989;31:123-7.
  11. Adler AJ, Berlyne GM. Duodenal aluminum absorption in the rat: effect of vitamin D. Am J Physiol 1985;249:G209-13. PubMed
  12. Schwartz JB. Effects of vitamin D supplementation in atorvastatin-treated patients: A new drug interaction with an unexpected consequence. Clin Pharmacol Ther 2009;85:198-203. PubMed
  13. Dietary reference intakes for calcium and vitamin D. Institute of Medicine, November 30, 2010. Available at: http://www.iom.edu/~/media/Files/Report%20Files/2010/Dietary-Reference-Intakes-for-Calcium-and-Vitamin-D/Vitamin%20D%20and%20Calcium%202010%20Repo
  14. Cox KA, Dunn MA. Aluminum toxicity alters the regulation of calbindin-D28k protein and mRNA expression in chick intestine. J Nutr 2001;131:2007-13. PubMed
  15. Escribano, J., Balaguer, A., Pagone, F., Feliu, A., and Roque, I. Figuls. Pharmacological interventions for preventing complications in idiopathic hypercalciuria. Cochrane.Database.Syst.Rev. 2009;(1):CD004754. PubMed
  16. Carlton, S., Clopton, D., and Cappuzzo, K. A. Vitamin D deficiency: appropriate replenishment therapies and the effects of vitamin D toxicity. Consult Pharm 2010;25(3):171-177. PubMed
  17. Wang, H., Xia, N., Yang, Y., and Peng, D. Q. Influence of vitamin D supplementation on plasma lipid profiles: a meta-analysis of randomized controlled trials. Lipids Health Dis. 2012;11:42. PubMed
  18. Turner AN, Carr Reese P, Fields KS, Anderson J, Ervin M, Davis JA, Fichorova RN, Roberts MW, Klebanoff MA, Jackson RD. A blinded, randomized controlled trial of high-dose vitamin D supplementation to reduce recurrence of bacterial vaginosis. Am J Obstet G PubMed
  19. Weiner M, Epstein FH. Signs and symptoms of electrolyte disorders. Yale J Biol Med. 1970;43(2):76-109.
  20. Lappe J, Watson P, Travers-Gustafson D, Recker R, Garland C, Gorham E, Baggerly K, McDonnell SL. Effect of Vitamin D and Calcium Supplementation on Cancer Incidence in Older Women: A Randomized Clinical Trial. JAMA. 2017 Mar 28;317(12):1234-1243. PubMed
  21. Roth DE, Leung M, Mesfin E, Qamar H, Watterworth J, Papp E. Vitamin D supplementation during pregnancy: state of the evidence from a systematic review of randomised trials. BMJ. 2017;359:j5237. PubMed
  22. Murai IH, Fernandes AL, Sales LP, et al. Effect of a single high dose of vitamin D3 on hospital length of stay in patients with moderate to severe COVID-19: A randomized clinical trial. JAMA. 2021.
  23. Wang Z, Schuetz EG, Xu Y, Thummel KE. Interplay between vitamin D and the drug metabolizing enzyme CYP3A4. J Steroid Biochem Mol Biol 2013;136:54-8. PubMed
  24. Doyle D, Browne U, Brickley A, Murphy D. Vitamin D-induced hypercalcaemia and acute kidney injury in sarcoidosis. BMJ Case Rep 2023;16(1):e250580. PubMed
  25. Williamson A, Martineau AR, Sheikh A, Jolliffe D, Griffiths CJ. Vitamin D for the management of asthma. Cochrane Database Syst Rev 2023;2(2):CD011511. PubMed
  26. Kinesya E, Santoso D, Gde Arya N, et al. Vitamin D as adjuvant therapy for diabetic foot ulcers: Systematic review and meta-analysis approach. Clin Nutr ESPEN 2023;54:137-143. PubMed

See these in context on the Vitamin D monograph →

Stevia 10 references
  1. Chan P, Xu DY, Liu JC, et al. The effect of stevioside on blood pressure and plasma catecholamines in spontaneously hypertensive rats. Life Sci 1998;63:1679-84. PubMed
  2. Melis MS. A crude extract of Stevia rebaudiana increases the renal plasma flow of normal and hypertensive rats. Braz J Med Biol Res 1996;29:669-75.
  3. Melis MS. Chronic administration of aqueous extract of Stevia rebaudiana in rats: renal effects. J Ethnopharmacol 1995;47:129-34. PubMed
  4. Melis MS, Sainati AR. Effect of calcium and verapamil on renal function of rats during treatment with stevioside. J Ethnopharmacol 1991;33:257-622. PubMed
  5. Hsieh MH, Chan P, Sue YM, et al. Efficacy and tolerability of oral stevioside in patients with mild essential hypertension: a two-year, randomized, placebo-controlled study. Clin Ther 2003;25:2797-808. PubMed
  6. Chan P, Tomlinson B, Chen YJ, et al. A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension. Br J Clin Pharmacol 2000;50:215-20. PubMed
  7. Gregersen S, Jeppesen PB, Holst JJ, Hermansen K. Antihyperglycemic effects of stevioside in type 2 diabetic subjects. Metabolism 2004;53:73-6. PubMed
  8. Barriocanal LA, Palacios M, Benitez G, et al. Apparent lack of pharmacological effect of steviol glycosides used as sweeteners in humans. A pilot study of repeated exposures in some normotensive and hypotensive individuals and in Type 1 and Type 2 diabeti
  9. Ferri LA, Alves-Do-Prado W, Yamada SS, et al. Investigation of the antihypertensive effect of oral crude stevioside in patients with mild essential hypertension. Phytother Res 2006;20:732-6. PubMed
  10. Almiron-Roig E, Navas-Carretero S, Castelnuovo G, et al. Impact of acute consumption of beverages containing plant-based or alternative sweetener blends on postprandial appetite, food intake, metabolism, and gastro-intestinal symptoms: Results of the SWEE

See these in context on the Stevia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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