Arjuna Bark Powder Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Arjuna Bark Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Arjuna Bark Powder is a dietary supplement by Bixa Botanical with 1 active ingredient. Its ingredients are commonly taken for heart health and circulation, digestive problems (constipation, diarrhea), cholesterol support.Based on those ingredients, 933 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Terminalia arjuna powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Arjuna Bark Powder by Bixa Botanical
Ask about any prescription or over-the-counter medication and we check it for interactions with Arjuna Bark Powder by Bixa Botanical — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Arjuna Bark Powder by Bixa Botanical
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Terminalia arjuna powder, an herb used traditionally to support heart and circulatory health. There are no inactive ingredients listed.
Does it work?
Not established
The evidence we hold on Terminalia arjuna doesn't establish that it works for the conditions it's often marketed for. We have insufficient reliable evidence to rate its use for obesity, high cholesterol (hyperlipidemia), high blood pressure (hypertension), and angina.
That doesn't mean it doesn't work — it means the studies available to us don't confirm it yet.
How safe is it?
Some data gaps
Terminalia arjuna is generally well tolerated in short-term studies, but we don't have solid data on what happens if you take it long-term, and quality can vary between products. The safety data advises against use during pregnancy and while breastfeeding, as there isn't enough information to know whether it's safe in those situations.
Meds to double-check
Moderate interaction found
Before taking Arjuna Bark Powder, double-check with your pharmacist if you take any blood thinners or antiplatelet drugs (like warfarin or aspirin), diabetes medications, drugs that are CYP2D6, CYP2C9, or CYP3A4 substrates (a large group including many common medications), chlorzoxazone, or omeprazole. All of these may be affected by this ingredient.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and some safety-information gaps remain.
This is a single-ingredient product that interacts with a broad range of medications, particularly blood thinners, diabetes drugs, and medications processed by major liver enzymes. If you take any prescription medications — especially for clotting, blood sugar, or heart conditions — you need to check them against our interaction tool before starting.
Talk with your pharmacist or doctor about whether this product is right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Arjuna Bark Powder, straight from the product label.
| Brand | Bixa Botanical |
|---|---|
| Barcode (UPC) | 8904289000152 |
| Net contents | 200 Gram(s); 7 Ounce(s) |
| Market status | On market |
| Date entered into DSLD | Jul 23, 2020 |
| DSLD ID | 229716 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Women (not pregnant or lactating) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Arjuna Bark Powder by Bixa Botanical, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Terminalia arjuna powder | 3 Gram(s) | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use: One - two teaspoon with warm water daily after food or as directed by your health practitioner.
Brand IP Statement(s)
Trademark of Bixa Botanical INC, USA
Mfg. Lic. No : MP25D/14/318
Formulation
Supports healthy heart functions
Vegan
Non GMO
FDA Statement of Identity
Herbal Food Supplement
FDA Disclaimer Statement
Disclaimer: These statements have not been evaluated by the Food and Drug Administration and this product is a herbal food supplement and not intended to diagnose, treat, cure or prevent a disease.
Precautions
Warning: Consuming this product can expose you to chemicals including lead which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.p65warnings.ca.gov/food.
This product is not intended for use by those with serious medical condition or pregnant or lactating women.
Consult your physician before use.
Do not use if seal is broken.
Keep out of reach of children.
Storage
Store in a cool and dry place.
General Statements
Product of India
Over 140 years of quality trust
More than a company, Bixa Botanical is a dream - to share the collective knowledge of five generations of a family with the world; secrets of Herbal Healing that have been painstakingly accumulated over the last 140 years. Over 500 varieties of herbs are exclusively cleaned, processed and packed-in the company's ultra-modern in-house facilities.
Seals/Symbols
Good manufacturing practices GMP Certified K LBD (Kosher)
Formula
K LBD (Kosher)
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Arjuna Bark Powder by Bixa Botanical label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Arjuna Bark Powder by Bixa Botanical
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Gram(s) Dosage formPowder Servings per container66 Amounts shown are per serving.
Terminalia arjuna powder
Interacts with933 drugs
Terminalia is a group of traditional Ayurvedic tree species (most notably Terminalia arjuna) used for heart, digestive, and general wellness purposes....
Terminalia arjuna powder monograph & interactionsArjuna Bark Powder by Bixa Botanical Drug Interactions
HelloPharmacist Interaction Report
Arjuna Bark Powder by Bixa Botanical contains one ingredient — Terminalia arjuna powder — that interacts with a significant number of medications.
The most serious concern is with blood thinners and antiplatelet drugs (medications that prevent clots). Terminalia arjuna can increase bleeding risk by inhibiting platelet aggregation and reducing how your blood clots.
Read the full breakdown — every affected drug type, severity by severity
Beyond that, this ingredient affects how your liver breaks down many other drugs. It inhibits three major enzyme systems — CYP2D6, CYP2C9, and CYP3A4 — which means it can raise the levels of medications that depend on those enzymes to be cleared from your body.
This could make those drugs more potent and increase the risk of side effects. Additionally, if you take diabetes medication, Terminalia arjuna may lower your blood sugar further and raise the risk of low blood sugar (hypoglycemia).
There are also documented interactions with the muscle relaxant chlorzoxazone and the heartburn drug omeprazole.
Altogether, these interactions span 922 individual medications. Please check your exact medications with the search tool on this page before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Arjuna Bark Powder?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Arjuna Bark Powder interact with 933 drugs. Click any drug to see the details.
1 of the 1 ingredient in Arjuna Bark Powder interact with drugs. Each result below shows which ingredient is responsible. Terminalia arjuna powder
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Terminalia Arjuna Powder + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Terminalia Arjuna Powder + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Read the full Terminalia Arjuna Powder + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Terminalia Arjuna Powder + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Terminalia Arjuna Powder + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
Read the full Terminalia Arjuna Powder + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Arjuna Bark Powder — through 1 ingredient. Tap an ingredient for the detail:
Terminalia Arjuna PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
Read the full Terminalia Arjuna Powder + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Arjuna Bark Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Terminalia arjuna powder
Anticoagulant/Antiplatelet Drugs
Theoretically, concomitant use of Terminalia arjuna with anticoagulant or antiplatelet drugs may increase the risk of bleeding in some patients.
In vitro, Terminalia arjuna bark extract inhibits platelet aggregation, decreases platelet activation, and shows antithrombotic properties.
Antidiabetes Drugs
Theoretically, concomitant use of Terminalia bellirica or Terminalia chebula with antidiabetes drugs could affect blood sugar control and increase the risk of hypoglycemia.
Animal and in vitro research shows that Terminalia bellirica and Terminalia chebula fruit and seed extract have hypoglycemic effects.
Chlorzoxazone (Parafon Forte, Paraflex)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from chlorzoxazone.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of chlorzoxazone increases blood levels of chlorzoxazone and decreases chlorzoxazone clearance. It is speculated that Terminalia chebula reduces the metabolism of chlorzoxazone by inhibiting cytochrome P450 2E1.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2C9 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2C9 enzymes and reduces CYP2C9 substrate metabolism.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP2D6 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP2D6 enzymes and reduces CYP2D6 substrate metabolism.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of Terminalia arjuna may increase the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that Terminalia arjuna extract inhibits CYP3A4 enzymes and reduces CYP3A4 substrate metabolism.
Omeprazole (Prilosec)
Theoretically, use of Terminalia chebula may increase the risk of adverse effects from omeprazole.
Animal research shows that enteral administration of Terminalia chebula for 15 days prior to administration of omeprazole increases blood levels of omeprazole and decreases omeprazole clearance. It is speculated that Terminalia chebula reduces the metabolism of omeprazole by inhibiting cytochrome P450 2C19.
Brand information
Manufacturer and brand details for Arjuna Bark Powder, from the product label.
Bixa Botanical
See all Bixa Botanical products- Name
- Stelcore Management Service LLC
- Street Address
- 8, Green Suite, #5766
- City
- Dover
- State
- Delaware
- ZipCode
- 19901
- Phone Number
- +1281897875
Arjuna Bark Powder by Bixa Botanical: Common Questions
Does Arjuna Bark Powder by Bixa Botanical interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is it safe to take this during pregnancy or while breastfeeding?
Will this actually help my heart health?
What's in this powder besides the active ingredient?
How long is it safe to take this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Arjuna Bark Powder is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Arjuna Bark Powder’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Arjuna Bark Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 9 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Terminalia 9 references
- Sabu, M. C. and Kuttan, R. Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J Ethnopharmacol. 2002;81(2):155-160. PubMed
- Rao, N. K. and Nammi, S. Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats. BMC.Complement Altern.Med 2006;6:17. PubMed
- Murali, Y. K., Anand, P., Tandon, V., Singh, R., Chandra, R., and Murthy, P. S. Long-term effects of Terminalia chebula Retz. on hyperglycemia and associated hyperlipidemia, tissue glycogen content and in vitro release of insulin in streptozotocin induced
- Senthilkumar, G. P. and Subramanian, S. Evaluation of antioxidant potential of Terminalia chebula fruits studies in streptozotocin-induced diabetic rats. Pharmaceutical Biology (Netherlands) 2007;45:511-518.
- Malik N, Dhawan V, Bahl A, Kaul D. Inihbitory effects of Terminalia arjuna on platelet activation in vitro in healthy subjects and patients with coronary artery disease. Platelets. 2009;20(3):183-1190.
- Varghese A, Savai J, Pandita N, Gaud RS. In vitro modulatory effects of Terminalia arjuna, arjunic acid, arjunetin, and arjungenin on CYP3A4, CYP2D6, and CYP2C9 enzyme activity in human liver microsomes. Toxicology Reports. 2015(2):806-16. PubMed
- Wu G, Dong Z, Dong J, et al. Effects of mongolian medicine Terminalia chebula Retz. on 6 CYP450 enzymes in rats. Int J Clin Exp Pathol 2020;13(12):3128-3138.
- Das A, Naveen J, Sreerama YN, Gnanesh Kumar BS, Baskaran V. Low-glycemic foods with wheat, barley and herbs (Terminalia chebula, Terminalia bellerica and Emblica officinalis) inhibit a-amylase, a-glucosidase and DPP-IV activity in high fat and low dose st
- Eltimamy M, Elshamarka M, Aboelsaad M, Sayed M, Moawad H. Effects of alcoholic extract of Terminalia Chebula dried fruit on blood biochemical profile in diabetic rats. J Diabetes Metab Disord 2022;21(1):159-170. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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