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Dietary supplement

Astaxanthin 6 mg Ingredients & Drug Interactions

by Nature's Lab

Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Astaxanthin 6 mg is a dietary supplement by Nature's Lab with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are AstaReal. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Astaxanthin 6 mg by Nature's Lab

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: astaxanthin 6 mg (delivered as AstaReal). Astaxanthin is a carotenoid — a naturally occurring pigment — that your body gets primarily from sea organisms like algae, krill, and salmon.

It's an antioxidant that some people take for joint health, skin health, eye health, and athletic performance. The softgel capsule also contains extra virgin olive oil, bovine gelatin, glycerin, and purified water as inactive ingredients to deliver the astaxanthin.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Antioxidant support for eye, skin and cell health.
  • We looked for evidence on: Age-related macular degeneration (AMD), Aging skin, Dry eye, Sunburn, Exercise-induced muscle damage, Exercise-induced muscle soreness — and 3 related terms.
  • The closest evidence on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Dry eye, Exercise-induced muscle soreness, Sunburn, and more.

The evidence we hold doesn't establish that astaxanthin is effective for the conditions we have ratings on — age-related cognitive decline, age-related macular degeneration (AMD), aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome. All are rated as having insufficient reliable evidence to rate.

This doesn't mean it doesn't work; it means the scientific data available to us isn't strong enough to draw a firm conclusion either way.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated, though long-term safety data are limited. At the 6 mg dose in this product, the most common side effects reported in trials were abdominal pain, diarrhea, and red-colored stool — a harmless discoloration caused by the pigment itself.

A small number of trial participants at 6 mg experienced increased bowel movements and red stool; at much higher doses (40 mg daily), a small number reported severe stomach pain. There isn't enough safety data to recommend astaxanthin during pregnancy or while breastfeeding — talk with your doctor or pharmacist for personalized advice before using it in these situations.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check any medication your liver processes through the CYP3A4 pathway (Moderate severity) — astaxanthin may theoretically lower their levels, though this hasn't been reported in people. Also check drugs metabolized by CYP2B6 (Moderate severity) for the same reason.

Use the search tool on this page to run your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Astaxanthin is a pigment antioxidant that you'll find in seafood. This product is generally well tolerated at 6 mg, though digestive effects and red stool are possible.

Before you start, check your medications against the interactions listed below — especially if you take drugs processed by your liver. Talk to your pharmacist if you're pregnant, breastfeeding, or on a long-term medication.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Astaxanthin 6 mg, straight from the product label.

Brand Nature's Lab
Barcode (UPC) 818014017101
Net contents 60 Easy-to-Swallow Softgel(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 334712
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Astaxanthin 6 mg by Nature's Lab, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
UPC/BARCODE
818014017101
IngredientAmount% DV
AstaReal6 mg--

Other ingredients: Extra Virgin Olive Oil, Bovine Gelatin, Glycerin, Water, Purified

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Astaxanthin is a potent fat-soluble antioxidant from red marine microalgae that helps protect cell membranes from free radical damage. Astaxanthin is one of the most potent antioxidants found in the carotene or xanthophyll family. Astaxanthin helps support healthy skin texture and elasticity, vision health and joint health. This formula uses AstaREAL astaxanthin, one of the most studied brands of astaxanthin derived from Haematococcus pluvialis microalgae.

Astaxanthin 6 mg One-Per-Day Softgel AstaREAL

Precautions

Warnings: Pregnant or lactating women and people with known medical conditions and/or taking drugs should consult with a qualified healthcare practitioner prior to taking dietary supplements.

Discontinue use and consult your doctor if any adverse reactions occur.

Do not use if seal is broken.

Keep out of reach of children.

Packaged in a facility that also processes soy, egg, milk, fish, shellfish, tree nuts and sesame.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Manufactured in the USA with imported and US ingredients. With love from Nevada

Promotes Eye Health, Skin Elasticity & Cell Support

Free of: Sugar, salt, dairy, eggs, peanuts, tree nuts, fish, shellfish, yeast, wheat, soy, gluten, titanium dioxide, artificial colors and flavors.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take 1 softgel one time daily, preferably with a meal, or as directed by a qualified healthcare practitioner.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

AstaREAL is a registered trademark of Fuji Chemical Industry Co., Ltd.

See for yourself

Astaxanthin 6 mg by Nature's Lab label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Astaxanthin 6 mg by Nature's Lab

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

AstaReal

Interacts with
671 drugs
6 mg per serving Form: Astaxanthin, Natural

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

AstaReal monograph & interactions

Other (inactive) ingredients: Extra Virgin Olive Oil, Bovine Gelatin, Glycerin, Water, Purified. These complete the product’s ingredient list but are not active constituents.

Interaction report

Astaxanthin 6 mg by Nature's Lab Drug Interactions

Want to check YOUR meds against Astaxanthin 6 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

AstaReal 671

Each ingredient & the kinds of drugs it affects

For each ingredient in Astaxanthin 6 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

AstaReal2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Astaxanthin 6 mg, from the product label.

Nature's Lab

See all Nature's Lab products
Name
Nature's Lab
Street Address
6980 W. Warm Springs Rd. Ste. 100
City
Las Vegas
State
NV
ZipCode
89113
Phone Number
1-800-211-4188
Web Address
NaturesLab.com
Pharmacist Counseling Corner

Astaxanthin 6 mg by Nature's Lab: Common Questions

Does Astaxanthin 6 mg by Nature's Lab interact with any medications?
Yes. Based on its ingredients, Astaxanthin 6 mg has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Astaxanthin 6 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is astaxanthin, and where does it come from?
Astaxanthin is a carotenoid — a natural pigment your body gets from sea organisms like algae, krill, and salmon. It's an antioxidant that some people use for joint, skin, eye, and athletic support, though we don't have strong evidence for any of those uses yet.
Will this turn my stool red?
It might. Red-colored stool is a harmless side effect caused by the astaxanthin pigment itself and was reported in a small number of people taking 6 mg daily in trials. It's not dangerous — just a cosmetic change.
Is astaxanthin safe to take while pregnant or breastfeeding?
There isn't enough safety data either way. Talk with your doctor or pharmacist about whether it's right for you in these situations — they can weigh the risks and benefits for your specific situation.
How much evidence is there that this works?
For the uses we have data on — cognitive decline, macular degeneration, aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome — the evidence isn't strong enough to rate. That doesn't mean it doesn't work; we just don't have reliable science to confirm it yet.
What are the inactive ingredients in this softgel?
Extra virgin olive oil, bovine gelatin, glycerin, and purified water. These help deliver the astaxanthin and form the capsule itself.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Astaxanthin 6 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Astaxanthin 6 mg label
Sources

Sources & How We Checked

Astaxanthin 6 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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