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Dietary supplement

Bai-Zhu Atractylodes Ingredients & Drug Interactions

by Herbalist & Alchemist

Bai-Zhu Atractylodes label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bai-Zhu Atractylodes against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bai-Zhu Atractylodes is a dietary supplement by Herbalist & Alchemist with 1 active ingredient. Its ingredients are commonly taken for digestive upset and poor appetite, bloating and fluid retention, general fatigue or 'weakness'.Based on those ingredients, 801 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are dried Bai-Zhu Atractylodes rhizome extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Bai-Zhu Atractylodes by Herbalist & Alchemist

Ask about any prescription or over-the-counter medication and we check it for interactions with Bai-Zhu Atractylodes by Herbalist & Alchemist — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Bai-Zhu Atractylodes by Herbalist & Alchemist

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: dried Bai-Zhu Atractylodes rhizome extract, a traditional botanical used in herbal medicine. The extract is suspended in a base of ethyl alcohol and distilled water.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Atractylodes's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports Chinese stomach and spleen.
  • We looked for evidence on: Diarrhea, Abdominal pain, Digestive function, Appetite, Bloating.
  • The closest evidence on file: Atractylodes is rated "Insufficient Reliable Evidence To Rate" for Diarrhea (Natural Medicines).
  • Also on file: Atractylodes is rated "Insufficient Reliable Evidence To Rate" for Abdominal pain.

The evidence for atractylodes is insufficient to establish whether it works for any condition tracked in our data — including loss of appetite, weight loss from illness (cachexia), lung cancer, common cold, or diarrhea. Traditional use is not the same as proven effectiveness, and human studies are needed.

The evidence, ingredient by ingredient Atractylodes

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Human safety data for atractylodes are limited, so caution is warranted, especially under guidance from your healthcare provider. The most commonly reported side effects are allergic reaction, dry mouth, and nausea.

The facts advise against use during pregnancy because there isn't enough reliable safety data, and breastfeeding safety is unknown, so it's best avoided then too.

Side effects, ingredient by ingredient Atractylodes

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Atractylodes.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 802 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist if you're on any blood thinners or antiplatelet drugs (warfarin, aspirin, clopidogrel, apixaban, rivaroxaban, dabigatran), aromatase inhibitors used for breast cancer, hexobarbital, or any medications broken down by liver enzymes CYP1A2 or CYP3A4.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Bai-Zhu Atractylodes is a traditional single-herb supplement with moderate interactions mainly affecting blood thinners, certain cancer medications, and liver metabolism. If you take any prescriptions — especially anticoagulants — check them against this product first.

Talk to your pharmacist before you start, and definitely avoid it if you're pregnant or nursing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bai-Zhu Atractylodes, straight from the product label.

Brand Herbalist & Alchemist
Barcode (UPC) 667056106584
Net contents 2 fl. Oz.; 60 mL
Market status On market
Date entered into DSLD Mar 23, 2018
DSLD ID 83185
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Kosher
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bai-Zhu Atractylodes by Herbalist & Alchemist, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.5 mL
Maximum serving Sizes:
2 mL
Servings per container
30
UPC/BARCODE
667056106584
IngredientAmount% DV
dried Bai-Zhu Atractylodes rhizome extract2 mL--

Other ingredients: Ethyl Alcohol, distilled Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Atractylodes macrocephala

OK

General Statements

Supports Chinese stomach and spleen

Botanical preparation ratio 1:4

FDA Statement of Identity

Herbal Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: 30-40 drops (1.5-2 mL) in juice or water. Take 3 times per day. Shake well before using.

Precautions

Keep out of children's reach

FDA Disclaimer Statement

This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

General

NO. ATY-2 R1745TU

Seals/Symbols

OK

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bai-Zhu Atractylodes by Herbalist & Alchemist label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bai-Zhu Atractylodes label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bai-Zhu Atractylodes by Herbalist & Alchemist

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1.5 mL Dosage formLiquid Servings per container30 Amounts shown are per serving.

Dried Bai-Zhu Atractylodes rhizome extract

Interacts with
801 drugs
2 mL per serving

Atractylodes is a root used for centuries in traditional Chinese, Japanese, and Thai medicine, mostly for digestive complaints and fatigue, often as p...

Dried Bai-Zhu Atractylodes rhizome extract monograph & interactions

Other (inactive) ingredients: Ethyl Alcohol, Distilled Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bai-Zhu Atractylodes by Herbalist & Alchemist Drug Interactions

Want to check YOUR meds against Bai-Zhu Atractylodes?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
801Drugs
127 Moderate 674 Minor

Ingredients driving the most interactions

dried Bai-Zhu Atractylodes rhizome extract 801

Individual Drug Interactions

The ingredients in Bai-Zhu Atractylodes interact with 801 drugs. Click any drug to see the details.

1 of the 1 ingredient in Bai-Zhu Atractylodes interact with drugs. Each result below shows which ingredient is responsible. dried Bai-Zhu Atractylodes rhizome extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Bai-Zhu Atractylodes with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

dried Bai-Zhu Atractylodes rhizome extract5 drug types · 801 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Laboratory research suggests that atractylenolides II and III, constituents of atractylodes, reduce platelet activation. So far, this has not been shown in humans.

Likelihood Possible Evidence D
Aromatase Inhibitors

Theoretically, atractylodes may have an additive effect when used with other aromatase inhibitors.
Laboratory research suggests that atractylodes and its constituents exhibit aromatase inhibitor effects.

Likelihood Possible Evidence D
Hexobarbital

Theoretically, taking atractylodes may prolong the therapeutic and adverse effects of hexobarbital.
In animals, atractylodes has been shown to prolong the effects of hexobarbital. These effects have not been shown in humans.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
In animals, atractylodes administered at high doses has been shown to induce CYP1A2 activity. This effect has not been shown in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
In animals, atractylodes administered at high doses has been shown to inhibit CYP3A1 activity, which is a homolog to the human CYP3A4 enzyme. This effect has not been shown in humans.

Likelihood Possible Evidence D
dried Bai-Zhu Atractylodes rhizome extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bai-Zhu Atractylodes, from the product label.

Herbalist & Alchemist

See all Herbalist & Alchemist products
Name
Herbalist & Alchemist, Inc.
City
Washington
State
NJ
ZipCode
07882
Phone Number
800-611-8235
Web Address
www.herbalist-alchemist.com
Pharmacist Counseling Corner

Bai-Zhu Atractylodes by Herbalist & Alchemist: Common Questions

Does Bai-Zhu Atractylodes by Herbalist & Alchemist interact with any medications?
Yes. Based on its ingredients, Bai-Zhu Atractylodes has a known interaction with 801 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bai-Zhu Atractylodes contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
No. The safety data advise against use during pregnancy. If you're pregnant or planning to become pregnant, talk with your doctor or pharmacist before considering this product.
Is it safe to use while breastfeeding?
The safety data for breastfeeding are unknown, so it's best avoided. If you're nursing and interested in this supplement, check with your doctor or pharmacist first.
What are the side effects?
The most common ones reported are allergic reaction, dry mouth, and nausea. A thorough safety evaluation hasn't been done, so other effects may exist but aren't well documented yet.
Does atractylodes actually work for loss of appetite or digestive issues?
The evidence in our data is insufficient to say whether it works. It's used traditionally for these purposes, but human studies proving its effectiveness haven't been established.
Why does the label say it's made with ethyl alcohol?
Ethyl alcohol is used in this liquid formulation as a preservative and extraction solvent to keep the herb stable and bioavailable.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bai-Zhu Atractylodes label
Go deeper

The Full Monographs Behind Bai-Zhu Atractylodes’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Atractylodes

Interacts with 801 drugs

Atractylodes is a root used for centuries in traditional Chinese, Japanese, and Thai medicine, mostly for digestive complaints and fatigue, often as part of multi-herb formulas. Modern resea...

Read the full Atractylodes monograph →
Sources

Sources & How We Checked

Bai-Zhu Atractylodes's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Atractylodes 6 references
  1. Liu Y, Jia Z, Dong L, et al. A randomized pilot study of atractylenolide I on gastric cancer cachexia patients. Evid Based Complement Alternat Med 2008;5:337-44. PubMed
  2. Chen Y, Yang W, Guo L, Wu X, Zhang T, Liu J, Zhang J. Atractylodes lactone compounds inhibit platelet activation. Platelets. 2017 Mar;28(2):194-202. PubMed
  3. Jiang H, Shi J, Li Y. Screening for compounds with aromatase inhibiting activities from Atractylodes macrocephala Koidz. Molecules. 2011 Apr 14;16(4):3146-51. PubMed
  4. Koonrungsesomboon N, Na-Bangchang K, Karbwang J. Therapeutic potential and pharmacological activities of Atractylodes lancea (Thunb.) DC. Asian Pac J Trop Med. 2014 Jun;7(6):421-8. PubMed
  5. Li L, Tang LY, Man GC, Yeung BH, Lau CB, Leung PC, Wang CC. Potential reproductive toxicity of Largehead Atractylodes Rhizome, the most commonly used Chinese medicine for threatened miscarriage. Hum Reprod. 2011 Dec;26(12):3280-8. PubMed
  6. Muhamad N, Plengsuriyakarn T, Na-Bangchang K. Atractylodes lancea for cholangiocarcinoma: Modulatory effects on CYP1A2 and CYP3A1 and pharmacokinetics in rats and biodistribution in mice. PLoS One 2022;17(11):e0277614. PubMed

See these in context on the Atractylodes monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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