Beet Root Extra Strength 2000 mg Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Beet Root Extra Strength 2000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Beet Root Extra Strength 2000 mg is a dietary supplement by Futurebiotics with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, exercise and athletic performance, heart and circulation support.Based on those ingredients, 861 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beet, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Beet Root Extra Strength 2000 mg by Futurebiotics
Ask about any prescription or over-the-counter medication and we check it for interactions with Beet Root Extra Strength 2000 mg by Futurebiotics — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Beet Root Extra Strength 2000 mg by Futurebiotics
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: beet root extract powder at 2000 mg per serving. Beet root extract is a concentrated form of the beet plant, standardized to deliver its active compounds.
The tablet also includes several inactive ingredients — microcrystalline cellulose, croscarmellose sodium, stearic acid, magnesium stearate, silicon dioxide, hydroxypropyl methylcellulose, and polyethylene glycol — which are used as binders, flow agents, and capsule material.
Does it work?
Not established
The evidence for beet root is mixed. It's possibly effective for athletic performance and exercise-induced muscle soreness based on the data we hold.
For chronic obstructive pulmonary disease (COPD), the evidence suggests it's possibly ineffective. For high cholesterol (dyslipidemia) and cognitive function, there isn't enough reliable evidence yet to rate how well it works.
How safe is it?
Well-documented data
Beet is generally well tolerated as a food and when used as a medicinal supplement in the short term. The most common side effects are harmless — red or sometimes black stools and red urine from the beet pigment.
Rare but serious effects reported with large amounts include low blood calcium (hypocalcemia) and kidney damage. Since concentrated beet supplements lack long-term safety data, use caution if you're taking them regularly.
Meds to double-check
Moderate interaction found
Before taking this product, check your medications if you take CYP3A4 substrates (a very large drug class that includes many cholesterol, heart, immune, and psychiatric medications), blood pressure lowering drugs, or CYP1A2 substrates. The CYP3A4 interaction is the most serious.
Run your exact medications through the checker on this page.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
If you're interested in beet root for athletic performance or muscle soreness, this product is a reasonable option. But because beet interacts with a large number of medications — especially those broken down by your liver — you'll want to check your exact prescriptions with the tool on this page before starting.
Talk to your pharmacist if you're on blood pressure medication or any regularly used drug.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Beet Root Extra Strength 2000 mg, straight from the product label.
| Brand | Futurebiotics |
|---|---|
| Barcode (UPC) | 049479869121 |
| Net contents | 120 Vegetarian Tablet(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2024 |
| DSLD ID | 319845 |
| Product type | Botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Beet Root Extra Strength 2000 mg by Futurebiotics, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Beet, Powder | 2000 mg | -- |
| Beet Root Extract, Powder | 500 mg | -- |
Other ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Magnesium Stearate, Silicon Dioxide, Hydroxypropyl Methylcellulose, Polyethylene Glycol
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
Beets naturally contain nitrates, which have been shown to support vascular function, healthy circulation and overall heart health. When ingested, the dietary nitrates are converted into nitric oxide. By doing so, Beets help to dilate blood vessels, which promotes healthy blood flow and supports blood pressure levels that are already in a healthy range.
Laboratory tested GMO-free, gluten-free and soy-free, Futurebiotics Beet Root is in-house tested and carefully manufactured by trained professionals in our state-of-the-art facility that is located in Hauppauge, New York.
Laboratory tested GMO-free, gluten-free and soy-free, Futurebiotics Beet Root is in-house tested and carefully manufactured by trained professionals in our state-of-the-art facility that is located in Hauppauge, New York.
Heart, circulation & stamina
Free of gluten & soy Lab tested GMO free
Formula
Futurebiotics Beet Root provides 2000mg of Beets per serving (from 4:1 extract) to help the body maintain healthy cardiovascular function.
Beet Root Extra Strength 2000mg per serving
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement for adults, take 2 tablets daily, preferably with a meal or as directed by a healthcare professional.
Precautions
Warning: Do not take if you are pregnant or nursing. Consult a healthcare professional prior to use if you are taking any medications.
Do not use if seal under cap is broken or missing.
Keep out of reach of children.
Storage
Store at room temperature.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Seals/Symbols
Lab tested GMO free
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Beet Root Extra Strength 2000 mg by Futurebiotics label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Beet Root Extra Strength 2000 mg by Futurebiotics
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.
Beet, Powder
Interacts with861 drugs
Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...
Beet, Powder monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Magnesium Stearate, Silicon Dioxide, Hydroxypropyl Methylcellulose, Polyethylene Glycol. These complete the product’s ingredient list but are not active constituents.
Beet Root Extra Strength 2000 mg by Futurebiotics Drug Interactions
HelloPharmacist Interaction Report
Beet Root Extra Strength 2000 mg by Futurebiotics contains beet root extract, which interacts with a meaningful group of medications.
The most serious concern is with CYP3A4 substrates (a large enzyme family your liver uses to break down many drugs) — beet's active pigment, betanin, may slow how quickly your body clears these medications, raising their levels in your blood. This is rated Moderate severity.
Read the full breakdown — every affected drug type, severity by severity
Beet also interacts with medications that lower blood pressure (antihypertensive drugs) — the nitrates in beet can relax blood vessels and drop your blood pressure further, though one clinical study found no significant effect. This is Minor severity.
Additionally, beet may theoretically speed up the clearance of CYP1A2 substrates, another enzyme family, which could weaken their effects — also Minor.
Although the facts don't name every medication in these categories, they span a very large number of drugs across multiple categories. Use the interaction checker on this page with your exact medications before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Beet Root Extra Strength 2000 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Beet Root Extra Strength 2000 mg interact with 861 drugs. Click any drug to see the details.
1 of the 1 ingredient in Beet Root Extra Strength 2000 mg interact with drugs. Each result below shows which ingredient is responsible. Beet, Powder
Acetaminophen, Dextromethorphan, Guaifenesin, PhenylpropanolamineAnatuss
How Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Acetaminophen, Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionAcetaminophen, Dextromethorphan, Guaifenesin, PseudoephedrineRobitussin Cold, Severe Cold, Suphedrine Cold/Cough
How Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Acetaminophen, Dextromethorphan, Guaifenesin, Pseudoephedrine interactionAcetaminophen, Dextromethorphan, Phenylpropanolamine, PyrilamineTheracaps
How Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Acetaminophen, Dextromethorphan, Phenylpropanolamine, Pyrilamine interactionAcetaminophen, Dextromethorphan, PseudoephedrineAlka-Seltzer PLUS Flu Liquid Gels, Non Aspirin Cold Caps, Tylenol Cold, Tylenol Flu Daytime Ex Strength, Tylenol Flu Ex Strength
How Acetaminophen, Dextromethorphan, Pseudoephedrine interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract, Powder + Acetaminophen, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract, Powder + Acetaminophen, Hydrocodone interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAdagrasibKrazati
How Adagrasib interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Adagrasib interactionAlfentanilAlfenta
How Alfentanil interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Alfentanil interactionAlfuzosinUroxatral
How Alfuzosin interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Alfuzosin interactionAliskirenTekturna
How Aliskiren interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Aliskiren interactionAlmotriptanAlmogran, Axert
How Almotriptan interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Almotriptan interactionAlogliptinNesina
How Alogliptin interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Alogliptin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Alogliptin, Pioglitazone interactionAlpelisibPiqray
How Alpelisib interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Alpelisib interactionAlprazolamNiravam, Xanax
How Alprazolam interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Alprazolam interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Ambrisentan interactionAmiodaroneCordarone, Pacerone
How Amiodarone interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Amiodarone interactionAmitriptylineElavil
How Amitriptyline interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Amitriptyline interactionAmitriptyline, ChlordiazepoxideLimbitrol DS
How Amitriptyline, Chlordiazepoxide interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract, Powder + Amitriptyline, Chlordiazepoxide interactionAmitriptyline, PerphenazineEtrafon, Etrafon-A, Etrafon-Forte, Triavil
How Amitriptyline, Perphenazine interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Beet Root Extract, Powder + Amitriptyline, Perphenazine interactionAmlodipineNorliqva
How Amlodipine interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet Root Extract, Powder + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet Root Extract, Powder + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet Root Extract, Powder + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure.
Read the full Beet Root Extract, Powder + Amlodipine, Celecoxib interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmprenavirAgenerase
How Amprenavir interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Amprenavir interactionApalutamideErleada
How Apalutamide interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Apalutamide interactionApixabanEliquis
How Apixaban interacts with Beet Root Extra Strength 2000 mg — through 1 ingredient. Tap an ingredient for the detail:
Beet Root Extract, PowderCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, beet might increase the levels of CYP3A4 substrates.
Read the full Beet Root Extract, Powder + Apixaban interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Beet Root Extra Strength 2000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Beet, Powder
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.
Antihypertensive Drugs
Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.
Brand information
Manufacturer and brand details for Beet Root Extra Strength 2000 mg, from the product label.
Futurebiotics
See all Futurebiotics products- Name
- Futurebiotics
- City
- Hauppauge
- State
- NY
- ZipCode
- 11788
- Phone Number
- (800) 367-5433
- Web Address
- www.futurebiotics.com
Beet Root Extra Strength 2000 mg by Futurebiotics: Common Questions
Does Beet Root Extra Strength 2000 mg by Futurebiotics interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm on blood pressure medication?
Will my urine and stools really turn red?
Does beet actually help with exercise performance?
Is beet safe long-term?
What's the difference between 'beet powder' and 'beet root extract'?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Beet Root Extra Strength 2000 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Beet Root Extra Strength 2000 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Beet Root Extra Strength 2000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 14 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Beet 14 references
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
- Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
- Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
- Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
- Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
- Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
- Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
- Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
- Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
- Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
- Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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