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Dietary supplement

Bergamot Ingredients & Drug Interactions

by NHC Natural Healthy Concepts

Bergamot label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bergamot against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bergamot is a dietary supplement by NHC Natural Healthy Concepts with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart and metabolic health, anxiety and stress (aromatherapy).Based on those ingredients, 410 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bergamonte. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Bergamot by NHC Natural Healthy Concepts

Ask about any prescription or over-the-counter medication and we check it for interactions with Bergamot by NHC Natural Healthy Concepts — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Bergamot by NHC Natural Healthy Concepts

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: bergamonte, a bergamot extract. Bergamot is a citrus fruit, and the extract has been studied for its effects on cholesterol and liver health.

The capsule itself and the other ingredients — magnesium stearate, stearic acid, and silicon dioxide — are inactive fillers and binders.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Metabolic and cholesterol health support.
  • We looked for evidence on: Hyperlipidemia, Metabolic syndrome, Nonalcoholic fatty liver disease (NAFLD), Obesity, Impaired glucose tolerance (prediabetes), Cardiovascular health — and 1 related terms.
  • The strongest evidence on file: Bergamot is rated "Possibly Effective" for Hyperlipidemia (Natural Medicines).
  • Also on file: Bergamot is rated "Insufficient Reliable Evidence To Rate" for Nonalcoholic fatty liver disease (NAFLD), Obesity, Impaired glucose tolerance (prediabetes), Metabolic syndrome.

The data shows bergamot is possibly effective for high cholesterol (hyperlipidemia). For mental alertness, the evidence suggests it's possibly ineffective.

For nonalcoholic fatty liver disease and autism spectrum disorder, we don't yet have enough reliable evidence to rate whether it works.

The evidence, ingredient by ingredient Bergamot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bergamot extract by mouth appears generally well tolerated in the short term, though one person in clinical trials reported heartburn. The safety picture changes if you're using the essential oil — it can be toxic if swallowed and cause sun-related skin reactions.

Topically, bergamot can cause blisters, redness, photosensitivity, pigment spots, and skin lesions, especially in fair-skinned people and with frequent contact. During pregnancy, there isn't enough safety data, so the advice is to avoid it.

Breastfeeding safety is also unknown, and avoiding it is the safer choice. If you're pregnant or nursing, talk to your doctor or pharmacist before starting any bergamot supplement.

Side effects, ingredient by ingredient Bergamot

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bergamot.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 410 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, double-check with your pharmacist if you take photosensitizing drugs or medications to control blood sugar. Both interactions are Moderate severity, meaning bergamot could affect how these medications work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you have high cholesterol and aren't on blood-sugar or photosensitizing medications, bergamot may be worth considering. If you take antidiabetes drugs or photosensitizing medications, you'll want to check with your pharmacist first.

Pregnant and breastfeeding people should avoid it.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bergamot, straight from the product label.

Brand NHC Natural Healthy Concepts
Barcode (UPC) 647732925654
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 318474
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bergamot by NHC Natural Healthy Concepts, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
647732925654
IngredientAmount% DV
Bergamonte1 Gram(s)--

Other ingredients: Capsule, Magnesium Stearate, Stearic Acid, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: 2 capsules per day or as recommended by your health care professional.

Formulation

Formulated to be free of allergens derived from: Gluten, corn, yeast, artificial colors and flavors.

Vcaps

Precautions

If you are pregnant or nursing, consult your physician before taking this product.

As with all dietary supplements some individuals may not tolerate or may be allergic to the ingredients used.

Please read the ingredient panel carefully prior to ingestion. Cease taking this product and consult your physician if you have negative reactions upon ingestion.

Keep out of reach of children.

This product was sealed for your protection. Do not use if outer logoed neck seal or inner-seal is missing or damaged.

Professional use only

Storage

Keep container tightly closed. Store at room temperature.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Bergamonte and Bergamot Polyphenolic Fraction are the registered trademark of HP ingredients.

Formula

Vcaps

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bergamot by NHC Natural Healthy Concepts label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bergamot label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bergamot by NHC Natural Healthy Concepts

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Bergamonte

Interacts with
410 drugs
1 Gram(s) per serving Form: Bergamot Orange Fruit Extract

Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some early but...

Bergamonte monograph & interactions

Other (inactive) ingredients: Capsule, Magnesium Stearate, Stearic Acid, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bergamot by NHC Natural Healthy Concepts Drug Interactions

Want to check YOUR meds against Bergamot?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
410Drugs
410 Moderate

Ingredients driving the most interactions

Bergamonte 410

Individual Drug Interactions

The ingredients in Bergamot interact with 410 drugs. Click any drug to see the details.

1 of the 1 ingredient in Bergamot interact with drugs. Each result below shows which ingredient is responsible. Bergamonte

Each ingredient & the kinds of drugs it affects

For each ingredient in Bergamot with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bergamonte2 drug types · 410 drugs

Antidiabetes Drugs

Theoretically, taking bergamot with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that bergamot juice has hypoglycemic effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.
Bergamot contains bergapten, which has photosensitizing effects.

Likelihood Probable Evidence D
Bergamonte full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bergamot, from the product label.

NHC Natural Healthy Concepts

See all NHC Natural Healthy Concepts products
Name
NHC
Street Address
310 N Westhill Blvd.
City
Appleton
State
WI
ZipCode
54914
Pharmacist Counseling Corner

Bergamot by NHC Natural Healthy Concepts: Common Questions

Does Bergamot by NHC Natural Healthy Concepts interact with any medications?
Yes. Based on its ingredients, Bergamot has a known interaction with 410 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bergamot contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is bergamot extract the same as bergamot oil?
No — and that matters for safety. This product is an oral extract, which is generally well tolerated. Bergamot essential oil can be toxic if you swallow it and causes sun-related skin reactions. Don't confuse the two.
Can I use this if I take diabetes medication?
Not without checking first. Bergamot may lower blood sugar, so combining it with antidiabetes drugs could drop your blood sugar too low. Talk to your pharmacist about whether it's safe for you.
Will this help my cholesterol?
The evidence says bergamot is possibly effective for high cholesterol, so it may help — but 'possibly' means the data isn't rock-solid yet. It's worth discussing with your doctor to see if it fits your plan.
Is it safe during pregnancy or while breastfeeding?
No. There isn't enough safety data in pregnancy, and breastfeeding safety is unknown. The safer choice is to avoid bergamot during both. Talk to your doctor if you're thinking about it.
What side effects should I expect?
Taken by mouth short-term, bergamot is well tolerated — one person reported heartburn in trials. If you're using it topically or getting frequent skin contact with the peel or oil, you risk blisters, redness, and sun sensitivity. Swallowing the essential oil is toxic.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bergamot is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bergamot label
Go deeper

The Full Monographs Behind Bergamot’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bergamot

Interacts with 410 drugs

Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some early but promising research. The essential oil i...

Read the full Bergamot monograph →
Sources

Sources & How We Checked

Bergamot's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bergamot 17 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Naganuma M, Hirose S, Nakayama Y, et al. A study of the phototoxicity of lemon oil. Arch Dermatol Res 1985;278:31-6. . PubMed
  4. Kaddu, S., Kerl, H., and Wolf, P. Accidental bullous phototoxic reactions to bergamot aromatherapy oil. J.Am.Acad.Dermatol. 2001;45(3):458-461. PubMed
  5. Finsterer, J. Earl Grey tea intoxication. Lancet 4-27-2002;359(9316):1484. PubMed
  6. Gruson, L. M. and Chang, M. W. Berloque dermatitis mimicking child abuse. Arch.Pediatr.Adolesc.Med. 2002;156(11):1091-1093. PubMed
  7. Weisenseel, P. and Woitalla, S. [Toxic mustard plaster dematitis and phototoxic dematitis after application of bergamot oil]. MMW.Fortschr.Med. 12-15-2005;147(51-52):53, 55.
  8. Placzek, M., Fromel, W., Eberlein, B., Gilbertz, K. P., and Przybilla, B. Evaluation of phototoxic properties of fragrances. Acta Derm.Venereol. 2007;87(4):312-316. PubMed
  9. Mollace, V., Sacco, I., Janda, E., Malara, C., Ventrice, D., Colica, C., Visalli, V., Muscoli, S., Ragusa, S., Muscoli, C., Rotiroti, D., and Romeo, F. Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies. F PubMed
  10. Morliere, P., Huppe, G., Averbeck, D., Young, A. R., Santus, R., and Dubertret, L. In vitro photostability and photosensitizing properties of bergamot oil. Effects of a cinnamate sunscreen. J.Photochem.Photobiol.B 1990;7(2-4):199-208. PubMed
  11. Young, A. R., Walker, S. L., Kinley, J. S., Plastow, S. R., Averbeck, D., Morliere, P., and Dubertret, L. Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model. J.P PubMed
  12. Girard, J., Unkovic, J., Delahayes, J., and Lafille, C. [Phototoxicity of Bergamot oil. Comparison between humans and guinea pigs]. Dermatologica 1979;158(4):229-243.
  13. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. II. Factors which affect the phototoxic reaction induced by bergamot oil and psoralen derivatives. Contact Dermatitis 1977;3(5):225-23 PubMed
  14. Zacher, K. D. and Ippen, H. [Contact dermatitis caused by bergamot oil]. Derm.Beruf.Umwelt. 1984;32(3):95-97.
  15. Yasui, Y. and Hirone, T. Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting. J.Dermatol. 1994;21(5):319-322. PubMed
  16. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. I. Characterization and quantification of the photoactive component. Br.J.Dermatol. 1977;96(5):475-482. PubMed
  17. Bruno A, Pandolfo G, Crucitti M, Cedro C, Zoccali RA, Muscatello MRA. Bergamot Polyphenolic Fraction Supplementation Improves Cognitive Functioning in Schizophrenia: Data From an 8-Week, Open-Label Pilot Study. J Clin Psychopharmacol 2017;37(4):468-71. PubMed

See these in context on the Bergamot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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