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Dietary supplement

Beta Glucans Ingredients & Drug Interactions

by Puritan's Pride

Beta Glucans label
See full label image
Other (e.g. Tea Bag) Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Beta Glucans against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Beta Glucans is a dietary supplement by Puritan's Pride with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart health, immune support.Based on those ingredients, 293 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beta-Glucan. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Beta Glucans by Puritan's Pride

Ask about any prescription or over-the-counter medication and we check it for interactions with Beta Glucans by Puritan's Pride — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Beta Glucans by Puritan's Pride

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: beta-glucan, a type of fiber derived from sources like oats, barley, and yeast. Beta-glucan is the part of these foods believed to support heart and cholesterol health.

The inactive ingredients are cellulose, stearic acid, silica, and magnesium stearate — standard binders and fillers that help form and preserve the product.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Beta-glucans's overall clinical evidence instead.

Strong

Strong clinical evidence supports Beta-glucans for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Coronary heart disease (CHD) — rated "Likely Effective" (Natural Medicines).
  • On file: Dyslipidemia — rated "Likely Effective" (Natural Medicines).

Beta-glucan is likely effective for two main purposes: lowering cholesterol (dyslipidemia) and supporting heart health in people with coronary heart disease. These ratings come from clinical research showing the ingredient can make a measurable difference in these areas.

The evidence, ingredient by ingredient Beta-glucans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beta-glucans from regular food are generally well tolerated. However, concentrated supplements are a different story — the safety data for high-dose supplements is limited, so caution is advised when using them long-term or at higher amounts.

When taken by mouth, beta-glucans are well tolerated overall. One trial in children and young adults did report a temporary rise in liver enzymes in one patient out of 44 shortly after starting a very high dose.

Regarding breastfeeding, there's little research on concentrated supplement doses, so caution is advised — talk with your doctor or pharmacist about whether it's right for you if you're nursing.

Side effects, ingredient by ingredient Beta-glucans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beta-glucans.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 293 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Puritan's Pride Beta Glucans, double-check with your doctor or pharmacist if you take blood pressure medications (antihypertensives) — beta-glucan can lower pressure and combining the two may drop it too far. Also check if you take immunosuppressants, since beta-glucan stimulates your immune system and could interfere with those drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Beta-glucan is likely effective for cholesterol and heart health, and it's generally well tolerated when taken by mouth. If you take blood pressure medications or drugs that suppress your immune system, check with your doctor or pharmacist first — this ingredient may affect how those work.

For personalized advice on whether it's right for you, talk it over with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beta Glucans, straight from the product label.

Brand Puritan's Pride
Barcode (UPC) 025077296866
Net contents 60 Coated Caplet(s)
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 286411
Product type Fiber And Other Nutrients
Supplement form Other (e.g. Tea Bag)
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beta Glucans by Puritan's Pride, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Caplet(s)
Maximum serving Sizes:
1 Caplet(s)
Servings per container
60
UPC/BARCODE
025077296866
IngredientAmount% DV
Calories5 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Beta-Glucan200 mg--

Other ingredients: Cellulose, Stearic Acid, Silica, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Puritan's Pride supplements are produced from the finest raw materials under stringent quality control standards. State-of-the-art manufacturing and packaging facilities ensure you the highest quality nutritional supplements money can buy. When it comes to your health...choose the best.

To reorder item # 29686 www.puritan.com 1-800-645-1030

Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Avoid this product if you are allergic to yeast.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Storage

Store at room temperature.

Brand IP Statement(s)

Copyright 2017 Puritan's Pride, Inc.

Seals/Symbols

QA Quality Assured

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, take one (1) caplet up to three times daily, preferably with meals.

Formulation

No artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no milk, no lactose, no soy, no gluten, no wheat, no fish. Sodium free.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Beta Glucans by Puritan's Pride label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Beta Glucans label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Beta Glucans by Puritan's Pride

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Caplet(s) Dosage formOther (e.g. Tea Bag) Servings per container60 Amounts shown are per serving.

Beta-Glucan

Interacts with
293 drugs
200 mg per serving Form: Beta-1,3-1,6-Glucan, Yeast Cell Wall Extract

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly low...

Beta-Glucan monograph & interactions

Other (inactive) ingredients: Cellulose, Stearic Acid, Silica, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beta Glucans by Puritan's Pride Drug Interactions

Want to check YOUR meds against Beta Glucans?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
293Drugs
293 Moderate

Ingredients driving the most interactions

Beta-Glucan 293

Individual Drug Interactions

The ingredients in Beta Glucans interact with 293 drugs. Click any drug to see the details.

1 of the 1 ingredient in Beta Glucans interact with drugs. Each result below shows which ingredient is responsible. Beta-Glucan

Each ingredient & the kinds of drugs it affects

For each ingredient in Beta Glucans with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beta-Glucan2 drug types · 293 drugs

Antihypertensive Drugs

Theoretically, taking beta-glucans with antihypertensive drugs might increase the risk of hypotension.
Clinical research shows that taking beta-glucans may reduce systolic and diastolic blood pressure in some hypertensive individuals.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, beta-glucans might interfere with immunosuppressive therapy.
Some clinical research shows that beta-glucans have immunostimulant effects.

Likelihood Possible Evidence D
Beta-Glucan full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Beta Glucans, from the product label.

Puritan's Pride

See all Puritan's Pride products
Name
Puritan's Pride, Inc.
City
Ronkonkoma
State
NY
ZipCode
11779
Phone Number
1-800-645-1030
Web Address
www.puritan.com
Pharmacist Counseling Corner

Beta Glucans by Puritan's Pride: Common Questions

Does Beta Glucans by Puritan's Pride interact with any medications?
Yes. Based on its ingredients, Beta Glucans has a known interaction with 293 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beta Glucans contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does beta-glucan actually work for heart health?
Yes — beta-glucan is rated likely effective for both high cholesterol and coronary heart disease based on clinical research. The evidence shows it can make a measurable difference in these areas.
Is this safe to take every day?
Beta-glucan from food sources is generally well tolerated, but concentrated supplements lack long-term safety data. Use caution with sustained high-dose supplementation, and talk with your doctor or pharmacist about what dose is right for you.
Can I take this while breastfeeding?
There isn't enough research on concentrated supplement doses during breastfeeding to say either way. Talk with your doctor or pharmacist to weigh the pros and cons for your situation.
What are the side effects?
When taken by mouth, beta-glucan is well tolerated — most people don't report problems. In one high-dose study in children, one participant had temporary liver enzyme elevation, but that's rare.
Why does the label say to be careful?
The label notes caution because we have good safety data for beta-glucan in food amounts, but much less for concentrated supplements at higher doses. Most side effects are mild or don't happen — caution just means use it as directed and keep an eye on how you feel.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beta Glucans is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beta Glucans label
Go deeper

The Full Monographs Behind Beta Glucans’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-glucans

Interacts with 293 drugs

Beta-glucans are natural fibers found in oats, barley, mushrooms, and yeast. The strongest evidence supports the oat and barley types for modestly lowering cholesterol and blood sugar, while...

Read the full Beta-glucans monograph →
Sources

Sources & How We Checked

Beta Glucans's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-glucans 11 references
  1. Katz, D. L., Nawaz, H., Boukhalil, J., Giannamore, V., Chan, W., Ahmadi, R., and Sarrel, P. M. Acute effects of oats and vitamin E on endothelial responses to ingested fat. Am.J.Prev.Med. 2001;20(2):124-129. PubMed
  2. Keenan, J. M., Pins, J. J., Frazel, C., Moran, A., and Turnquist, L. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial. J.Fam.Pract. 2002;51(4):369.
  3. Maki, K. C., Galant, R., Samuel, P., Tesser, J., Witchger, M. S., Ribaya-Mercado, J. D., Blumberg, J. B., and Geohas, J. Effects of consuming foods containing oat beta-glucan on blood pressure, carbohydrate metabolism and biomarkers of oxidative stress i
  4. Bergendiova, K., Tibenska, E., and Majtan, J. Pleuran (beta-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes. Eur.J.Appl.Physiol 2011;111(9):2033-2040.
  5. Talbott S, Talbott J. Effect of beta 1,3/1,6 glucan on respiratory tract infection symptoms and mood state in marathon athletes. J Sports Sci Med 2009;8(4):509-515.
  6. Feldman S, Schwartz HI Kalman DS Mayers A Kohrman HM Clemens R Krieger DR. Randomized phase II clinical trials of Wellmune WGP® for immune support during cold and flu season. The Journal of Applied Research 2009;9(1-2):30-42.
  7. McFarlin BK, Carpenter KC, Davidson T, McFarlin MA. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J Diet Suppl. 2013;10(3):171-83. PubMed
  8. Jesenak M, Urbancek S, Majtan J, Banovcin P, Hercogova J. ß-Glucan-based cream (containing pleuran isolated from pleurotus ostreatus) in supportive treatment of mild-to-moderate atopic dermatitis. J Dermatolog Treat 2016;27(4):351-4.
  9. Mah E, Kaden VN, Kelley KM, Liska DJ. Beverage containing dispersible yeast ß-glucan decreases cold/flu symptomatic days after intense exercise: a randomized controlled trial. J Diet Suppl 2020;17(2):200-10. PubMed
  10. Zhong K, Liu Z, Lu Y, Xu X. Effects of yeast ß-glucans for the prevention and treatment of upper respiratory tract infection in healthy subjects: a systematic review and meta-analysis. Eur J Nutr. 2021. PubMed
  11. Cardenas FI, Mauguen A, Cheung IY, et al. Phase I trial of oral yeast-derived ß-glucan to enhance anti-GD2 immunotherapy of resistant high-risk neuroblastoma. Cancers (Basel) 2021;13(24):6265. PubMed

See these in context on the Beta-glucans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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