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Dietary supplement

Beta Sitosterol Complex 667 mg Ingredients & Drug Interactions

by Wonder Laboratories

Beta Sitosterol Complex 667 mg label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Beta Sitosterol Complex 667 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Beta Sitosterol Complex 667 mg is a dietary supplement by Wonder Laboratories with 2 active ingredients. Its ingredients are commonly taken for diarrhea relief, constipation and digestive health, cholesterol support.Based on those ingredients, 23 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Citrus Pectin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Beta Sitosterol Complex 667 mg by Wonder Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Beta Sitosterol Complex 667 mg by Wonder Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Beta Sitosterol Complex 667 mg by Wonder Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • “Beta Sitosterol Complex” is a proprietary blend — the label gives one combined amount (667 mg) without saying how much of each component you get.

This product contains 4 active ingredients: citrus pectin, beta-sitosterol, stigmasterol, and campesterol. Beta-sitosterol is a plant sterol that may help manage cholesterol and support prostate health.

The other plant sterols and citrus pectin work alongside it. The tablet also contains inactive ingredients—calcium carbonate, vegetable cellulose, silica, vegetable magnesium stearate, and vegetable stearic acid—which are fillers and binders that give the tablet its form.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Benign prostatic hyperplasia (BPH) — rated "Likely Effective" (Beta-sitosterol) (Natural Medicines).
  • On file: Hypercholesterolemia — rated "Possibly Effective" (Pectin) (Natural Medicines).
  • On file: Coronary heart disease (CHD) — rated "Possibly Effective" (Beta-sitosterol) (Natural Medicines).
  • On file: Familial hypercholesterolemia — rated "Possibly Effective" (Beta-sitosterol) (Natural Medicines).

The evidence here is mixed. Citrus pectin is rated possibly effective for high cholesterol (hypercholesterolemia), though the evidence for prediabetes and radiation exposure is not established.

Beta-sitosterol is likely effective for benign prostatic hyperplasia (BPH)—enlarged prostate—and possibly effective for familial high cholesterol and coronary heart disease. We hold no effectiveness data for stigmasterol or campesterol.

The evidence, ingredient by ingredient Pectin Beta-sitosterol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Citrus pectin is generally well tolerated, though some people experience gas, loose stools, diarrhea, or mild cramping. Allergic reactions are rare but possible, even severe ones in sensitive individuals.

Beta-sitosterol is generally well tolerated short-term in adults but can cause constipation, diarrhea, gas, indigestion, nausea, or reduced appetite. There's a rare case report of acute pancreatitis linked to beta-sitosterol, and it may worsen acne in some people.

For pregnancy, the data on citrus pectin from supplements is insufficient—talk with your doctor before using it while pregnant or breastfeeding. Beta-sitosterol specifically should be avoided during pregnancy and breastfeeding due to lack of safety data.

Side effects, ingredient by ingredient Pectin Beta-sitosterol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Pectin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications.
  • For scale: 23 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take digoxin (Lanoxin), lovastatin (Mevacor), or tetracycline antibiotics. Citrus pectin in this product may reduce how much of these medications your body absorbs.

No other interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This is worth considering if you're managing cholesterol or prostate health and don't take digoxin, lovastatin, or tetracycline antibiotics. Those taking any heart or antibiotic medications should check with their doctor or pharmacist first.

Pregnant or breastfeeding individuals should talk it over with their provider before starting. If you have questions about your specific situation, your own doctor or pharmacist is the best resource.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 18, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beta Sitosterol Complex 667 mg, straight from the product label.

Brand Wonder Laboratories
Barcode (UPC) 099528584253
Net contents 250 Tablet(s)
Market status On market
Date entered into DSLD Dec 18, 2021
DSLD ID 262349
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beta Sitosterol Complex 667 mg by Wonder Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
250
UPC/BARCODE
099528584253
IngredientAmount% DV
Citrus Pectin30 mg--
Stigmasterol130 mg--
Beta Sitosterol300 mg--
Campesterol160 mg--
Beta Sitosterol Complex667 mg--

Other ingredients: Calcium Carbonate, Vegetable Cellulose, Silica, Vegetable Magnesium Stearate, Vegetable Stearic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 1 tablet three times daily, with meals. Tablets should be taken at least three times a day, whether meals are skipped or not. If meal is especially heavy or fat laden, take two or more tablets.

Precautions

Tamper evident: Do not use this product if imprinted foil seal under cap is broken or missing.

Keep out of reach of children.

Caution: If you are pregnant or nursing consult your physician before taking this product.

Formulation

Mfg. in an FDA Registered Facility using Good Manufacturing Practices (GMPs)

Conforms to USP <2091> for weight. Meets USP <2040> disintegration for maximum bioavailability.

Helps maintain cholesterol levels that are already within normal range and nutritionally supports healthy prostate function

Storage

Keep tightly closed. Store at room temperature: 59 degrees - 86 degrees F (15 degrees - 30 degrees C).

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Formula 584

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Beta Sitosterol Complex 667 mg by Wonder Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Beta Sitosterol Complex 667 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Beta Sitosterol Complex 667 mg by Wonder Laboratories

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container250 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Citrus Pectin

Interacts with
23 drugs
30 mg per serving

Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly he...

Citrus Pectin monograph & interactions

Beta Sitosterol Complex

No known
interactions
667 mg per serving

Beta-sitosterol is a plant sterol that may modestly lower LDL ('bad') cholesterol and may help ease urinary symptoms from an enlarged prostate. Eviden...

Beta Sitosterol Complex monograph & interactions

Other (inactive) ingredients: Calcium Carbonate, Vegetable Cellulose, Silica, Vegetable Magnesium Stearate, Vegetable Stearic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beta Sitosterol Complex 667 mg by Wonder Laboratories Drug Interactions

Want to check YOUR meds against Beta Sitosterol Complex 667 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
23Drugs
23 Moderate

Ingredients driving the most interactions

Citrus Pectin 23

Individual Drug Interactions

The ingredients in Beta Sitosterol Complex 667 mg interact with 23 drugs. Click any drug to see the details.

1 of the 2 ingredients in Beta Sitosterol Complex 667 mg interact with drugs. Each result below shows which ingredient is responsible. Citrus Pectin

Each ingredient & the kinds of drugs it affects

For each ingredient in Beta Sitosterol Complex 667 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Citrus Pectin3 drug types · 23 drugs

Digoxin (Lanoxin)

Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.

Likelihood Possible Evidence B
Lovastatin (Mevacor)

Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.

Likelihood Possible Evidence B
Citrus Pectin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Beta Sitosterol Complex 667 mg, from the product label.

Wonder Laboratories

See all Wonder Laboratories products
Name
Wonder Laboratories
City
White House
State
TN
ZipCode
37188
Pharmacist Counseling Corner

Beta Sitosterol Complex 667 mg by Wonder Laboratories: Common Questions

Does Beta Sitosterol Complex 667 mg by Wonder Laboratories interact with any medications?
Yes. Based on its ingredients, Beta Sitosterol Complex 667 mg has a known interaction with 23 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beta Sitosterol Complex 667 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Citrus pectin in this product may be safe in pregnancy—the data is limited—but beta-sitosterol specifically should be avoided because we don't have enough safety information. Talk with your doctor or pharmacist about whether this product is right for you during pregnancy or while breastfeeding.
What side effects might I notice?
The most common are digestive: gas, loose stools, diarrhea, constipation, nausea, or indigestion. These are usually mild. Rarely, people with pectin sensitivity may have an allergic reaction. If you notice anything concerning, stop and talk to your pharmacist.
Is this actually effective for cholesterol?
Citrus pectin is rated possibly effective for high cholesterol, and beta-sitosterol is possibly effective for familial high cholesterol and coronary heart disease. The evidence is promising but not definitive. Results vary from person to person, so discuss it with your doctor to see if it fits your plan.
Does beta-sitosterol help with prostate health?
Yes—beta-sitosterol is rated likely effective for benign prostatic hyperplasia, which is an enlarged prostate. That's one of its main uses.
What happens if I take this with my heart medication?
If you take digoxin (Lanoxin), citrus pectin in this product may reduce how much digoxin your body absorbs, which could make it less effective. Do not take them together without talking to your doctor or pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beta Sitosterol Complex 667 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beta Sitosterol Complex 667 mg label
Go deeper

The Full Monographs Behind Beta Sitosterol Complex 667 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pectin

Interacts with 23 drugs

Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and di...

Read the full Pectin monograph → Herb & supplement monograph

Beta-sitosterol

Beta-sitosterol is a plant sterol that may modestly lower LDL ('bad') cholesterol and may help ease urinary symptoms from an enlarged prostate. Evidence is moderate for these uses and weaker...

Read the full Beta-sitosterol monograph →
Sources

Sources & How We Checked

Beta Sitosterol Complex 667 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pectin 11 references
  1. Jaakkola MS, et al. Asthma caused by occupational exposure to pectin. J Allergy Clin Immunol 1997;100:575-6. PubMed
  2. Westphal W, et al. [Exogenous allergic asthma following pectin exposure-a new occupational allergen]. Pneumologie 1990;44(Suppl 1):337-8.
  3. Baldwin JL, et al. Pectin-induced occupational asthma. Chest 1993;104:1936-7. PubMed
  4. Cohen AJ, Forse MS, Tarlo SM. Occupational asthma caused by pectin inhalation during the manufacture of jam. Chest 1993;103:309-11.
  5. Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7. PubMed
  6. Richter WO, Jacob BG, Schwandt P. Interaction between fibre and lovastatin. Lancet 1991;338:706.
  7. Albert KS, Ayres JW, DiSanto AR, et al. Influence of kaolin-pectin suspension on digoxin bioavailability. J Pharm Sci 1978;67:1582-6. PubMed
  8. Albert KS, Welch RD, DeSante KA, et al. Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. J Pharm Sci 1979;68:586-8. PubMed
  9. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  10. Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
  11. Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157. PubMed

See these in context on the Pectin monograph →

Beta-sitosterol 7 references
  1. Berges RR, Windeler J, Trampisch HJ, et al. Randomised, placebo-controlled, double-blind clinical trial of beta-sitosterol in patients with benign prostatic hyperplasia. Beta-sitosterol Study Group. Lancet 1995;345:1529-32.
  2. Klippel KF, Hiltl DM, Schipp B. A multicentric, placebo-controlled, double-blind clinical trial of beta-sitosterol (phytosterol) for the treatment of benign prostatic hyperplasia. Br J Urol 1997;80:427-32.
  3. Wilt TJ, MacDonald R, Ishani A. beta-sitosterol for the treatment of benign prostatic hyperplasia: a systematic review. BJU Int 1999;83:976-83. PubMed
  4. Oster P, Schlierf G, Heuck CC, et al. [Sitosterol in familial hyperlipoproteinemia type II. A randomized, double-blind, cross-over study]. Dtsch Med Wochenschr 1976;101:1308-11.
  5. Becker M, Staab D, Von Bergman K. Long-term treatment of severe familial hypercholesterolemia in children: effect of sitosterol and bezafibrate. Pediatrics 1992;89:138-42. DOI
  6. Prager N, Bickett K, French N, Marcovici G. A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia. J Altern Complement Med 2002
  7. Lorenze A, Hsueh W, Nasr J. Beta-sitosterol-induced acute pancreatitis: A case report and review of the literature. Cureus. 2020;12(3):e7407. PubMed

See these in context on the Beta-sitosterol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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