No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Betaine Anhydrous Ingredients & Drug Interactions

by BodyTech

Betaine Anhydrous label
See full label image
Powder Category: Non-nutrient/non-botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Betaine Anhydrous against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Betaine Anhydrous is a dietary supplement by BodyTech with 1 active ingredient. Its ingredients are commonly taken for high homocysteine levels, liver health (fatty liver), exercise performance and strength.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of Betaine Anhydrous by BodyTech

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: betaine anhydrous. Betaine is a compound your body uses to help manage homocysteine (an amino acid in your blood), support cell function, and may play a role in liver health.

The powder form lets you control your dose, which is useful since betaine's effects depend on how much you take and why you're taking it.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports athletic performance strength and power.
  • We looked for evidence on: Athletic performance.
  • The closest evidence on file: Betaine Anhydrous is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).

Betaine anhydrous is effective for homocystinuria, a rare genetic condition where homocysteine builds up to dangerous levels. It's possibly effective for hyperhomocysteinemia (mild to moderate elevation of homocysteine in the blood).

For nonalcoholic fatty liver disease (NASH), colorectal cancer prevention, depression, and heartburn reflux (GERD), the evidence isn't strong enough yet to know whether it works — we simply don't have enough reliable data. Talk to your doctor about whether it's right for your specific situation.

The evidence, ingredient by ingredient Betaine Anhydrous

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Betaine anhydrous is generally well tolerated in studied doses, but the safety data overall isn't robust, so it's best to use it only if a healthcare provider recommends it. The most common side effects are body odor, diarrhea, nausea, vomiting, GI upset, and elevated cholesterol.

A rare serious side effect — cerebral edema (swelling in the brain) — has been reported orally. Safety data during breastfeeding is not well established, so caution is advised if you're nursing.

Side effects, ingredient by ingredient Betaine Anhydrous

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented for betaine anhydrous in our data. That said, check your exact medications with the search tool on this page — it's a small but smart extra step.

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Betaine anhydrous works well for homocystinuria and may help with mild homocysteine elevation, but most other uses lack strong evidence. Side effects like GI upset and body odor are common and generally mild.

If you're pregnant or breastfeeding, or if you're considering it for a condition beyond homocysteine management, talk with your pharmacist or doctor first.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 21, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Betaine Anhydrous, straight from the product label.

Brand BodyTech
Barcode (UPC) 766536001668
Net contents 2.65 Oz(s); 75 Gram(s)
Market status On market
Date entered into DSLD Nov 21, 2018
DSLD ID 183396
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Betaine Anhydrous by BodyTech, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2.5 Gram(s)
Maximum serving Sizes:
2.5 Gram(s)
Servings per container
30
UPC/BARCODE
766536001668
IngredientAmount% DV
Betaine Anhydrous2.5 Gram(s)--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Supports athletic performance Also supports strength & power Unflavored

Visit www.bodytech.com or call 1-800-223-1216 for more information and to reorder.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Mix one (1) scoop with 8 oz. of water either before or after exercise. You can combine it with your pre/intra/post-workout or protein supplements.

Precautions

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medication or have any medical conditions.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Storage

Store in a cool, dry place.

Seals/Symbols

Quality Promise Tested Trusted Guaranteed 30 day money back guarantee

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General

Item No. VS-0166 2133445 HS 64

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Betaine Anhydrous by BodyTech label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Betaine Anhydrous label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Betaine Anhydrous by BodyTech

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2.5 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Betaine Anhydrous

No known
interactions
2.5 Gram(s) per serving

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and a...

Betaine Anhydrous monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Betaine Anhydrous by BodyTech Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Betaine Anhydrous. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Betaine Anhydrous, from the product label.

BodyTech

See all BodyTech products
Name
Vitamin Shoppe, Inc.
City
Secaucus
State
NJ
ZipCode
07094
Phone Number
1-800-223-1216
Web Address
www.bodytech.com
Pharmacist Counseling Corner

Betaine Anhydrous by BodyTech: Common Questions

Does Betaine Anhydrous by BodyTech interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Betaine Anhydrous. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Betaine Anhydrous contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does betaine anhydrous do?
It helps your body manage homocysteine, an amino acid in your blood. It's proven effective for homocystinuria (a rare genetic disorder) and possibly helpful for mild homocysteine elevation. For other conditions like fatty liver disease, depression, and heartburn, there isn't enough strong evidence yet to say whether it works.
What are the side effects I should expect?
The most common ones are body odor, diarrhea, nausea, vomiting, stomach upset, and elevated cholesterol. Most people tolerate it well at studied doses, but check with your healthcare provider first. A rare serious side effect — brain swelling — has been reported, though it's uncommon.
Is it safe to take while breastfeeding?
Safety data while breastfeeding isn't well established, so caution is advised. Talk with your doctor or pharmacist before using it if you're nursing — they can help you weigh the benefit against any risk.
Is it safe during pregnancy?
There isn't enough reliable safety data during pregnancy, so it's best to avoid unless a doctor advises otherwise. If you're pregnant and think you might benefit, talk with your OB or pharmacist for personalized guidance.
Does it interact with my medications?
No interactions are documented in our data for betaine anhydrous. Still, run your exact medications through the search tool on this page to be sure, since new interactions can emerge and individual circumstances vary.
Why is this a powder instead of a capsule?
The powder form gives you flexibility to adjust your dose easily. You can mix it into a drink or food, which is helpful since betaine's effects depend on how much you take.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Betaine Anhydrous is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Betaine Anhydrous label
Go deeper

The Full Monographs Behind Betaine Anhydrous’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Betaine Anhydrous

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and as a prescription medicine for a rare gen...

Read the full Betaine Anhydrous monograph →
Sources

Sources & How We Checked

Betaine Anhydrous's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Betaine Anhydrous 11 references
  1. Cystadane (betaine anhydrous for oral solution) Package insert. Orphan Medical, Inc. Minnetonka, MN. November 2005.
  2. Abdelmalek MF, Angulo P, Jorgensen RA, et al. Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study. Am J Gastroenterol 2001;96:2711-7.. PubMed
  3. Schwab U, Torronen A, Toppinen L, et al. Betaine supplementation decreases plasma homocysteine concentrations but does not affect body weight, body composition, or resting energy expenditure in human subjects. Am J Clin Nutr 2002;76:961-7. PubMed
  4. McGregor DO, Dellow WJ, Robson RA, et al. Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure. Kidney Int 2002;61:1040-6. PubMed
  5. Olthof MR, van Vliet T, Verhoef P, et al. Effect of homocysteine-lowering nutrients on blood lipids: results from four randomised, placebo-controlled studies in healthy humans. PloS Med 2005;2:e135. PubMed
  6. Knopman, D. and Patterson, M. An open-label, 24-week pilot study of the methyl donor betaine in Alzheimer disease patients. Alzheimer Dis.Assoc.Disord. 2001;15(3):162-165. PubMed
  7. Moat, S. J., Madhavan, A., Taylor, S. Y., Payne, N., Allen, R. H., Stabler, S. P., Goodfellow, J., McDowell, I. F., Lewis, M. J., and Lang, D. High- but not low-dose folic acid improves endothelial function in coronary artery disease. Eur J Clin Invest 2 PubMed
  8. Abdelmalek, M. F., Sanderson, S. O., Angulo, P., Soldevila-Pico, C., Liu, C., Peter, J., Keach, J., Cave, M., Chen, T., McClain, C. J., and Lindor, K. D. Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial. Hepa PubMed
  9. Ashtary-Larky D, Bagheri R, Ghanavati M, et al. Effects of betaine supplementation on cardiovascular markers: a systematic review and meta-analysis. Crit Rev Food Sci Nutr. 2021 Mar 25:1-18. PubMed
  10. Zawieja EE, Zawieja B, Chmurzynska A. Betaine supplementation moderately increases total cholesterol levels: a systematic review and meta-analysis. J Diet Suppl. 2021;18(1):105-117. PubMed
  11. Imbard A, Toumazi A, Magréault S, et al. Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial. Orphanet J Rare Dis 2022;17(1):417. PubMed

See these in context on the Betaine Anhydrous monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team