Major interaction on record — check this product against your medications before combining. Based on 3 of 7 ingredients. Check your meds →
Dietary supplement

Bio-Gro Cookies N' Cream Ingredients & Drug Interactions

by iSatori

Bio-Gro Cookies N' Cream label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bio-Gro Cookies N' Cream against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Bio-Gro Cookies N' Cream is a dietary supplement by iSatori with 7 active ingredients. Its ingredients are commonly taken for bone health and osteoporosis prevention, dietary calcium deficiency, heartburn relief (calcium carbonate antacids).Based on those ingredients, 168 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Calcium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Bio-Gro Cookies N' Cream by iSatori

Ask about any prescription or over-the-counter medication and we check it for interactions with Bio-Gro Cookies N' Cream by iSatori — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Bio-Gro Cookies N' Cream by iSatori

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 6 active ingredients.
  • “Custom Engineered Bio-Pro Bio-Active Peptides” is listed as a grouped ingredient — the label gives one combined amount (1.50 Gram(s)) without saying how much of each component you get.

Bio-Gro Cookies N' Cream contains 6 active ingredients. The main one is calcium, a mineral your body needs for bone strength, muscle function, and nerve signaling.

The product also includes lactoferrin, a protein found naturally in milk that your immune system uses; Proline Rich Peptides, amino acid compounds sometimes studied for bone and wound health; and a proprietary blend called Custom Engineered Bio-Pro Bio-Active Peptides, which includes Growth Factors, Immunoglobulins, and Fibroblast-GF (growth-promoting proteins). The powder also contains inactive ingredients — sucralose (a sweetener), natural and artificial flavors, medium chain triglycerides (a fat), and sunflower lecithin (an emulsifier) — to make it taste like cookies and cream and mix smoothly.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Build muscle, recover faster, increase strength.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Muscle protein synthesis, Strength gains, Lean muscle development.
  • The closest evidence on file: Calcium is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle damage (Natural Medicines).
  • Also on file: Proline is rated "Insufficient Reliable Evidence To Rate" for Athletic performance.

Calcium in this product is effective for preventing and treating low calcium levels (hypocalcemia), high potassium (hyperkalemia), and upset stomach (dyspepsia), and is likely effective for osteoporosis. Lactoferrin shows possibly effective evidence for sepsis and pregnancy-related iron deficiency, but is likely ineffective for reducing death in newborns and premature infants from necrotizing enterocolitis.

Proline Rich Peptides have insufficient evidence to rate for athletic performance, osteoporosis, fractures, wound healing, and low bone density (osteopenia). The other active ingredients — Growth Factors, Immunoglobulins, and Fibroblast-GF — do not have effectiveness data on file.

The evidence, ingredient by ingredient Calcium Lactoferrin Proline

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Calcium is generally well tolerated at recommended doses, though high amounts can cause problems. Common side effects are belching, constipation, diarrhea, gas, and stomach upset.

There is rare concern about kidney stones and a condition called calciphylaxis. Some evidence suggests very high calcium intake (over 1500–2000 mg daily) may be linked to increased prostate cancer risk and possibly heart disease, though these findings are debated.

Lactoferrin is generally well tolerated at typical doses but has limited long-term safety data. Higher doses of 7.2 grams daily raise the risk of side effects.

Common side effects include constipation and diarrhea; at high doses, fatigue and loss of appetite have been reported. In newborns, rare cases of jaundice, bloody stool, and bowel problems have been reported.

Proline Rich Peptides have not been well studied as a supplement, so long-term safety is unclear. Pregnancy safety data for lactoferrin and Proline Rich Peptides are not well established — talk with your doctor or pharmacist if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Calcium Lactoferrin Proline

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 3 matched ingredients can interact with medications — Calcium.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: heart-rhythm medications; lithium.
  • For scale: 168 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Bio-Gro Cookies N' Cream, check with your pharmacist if you take any HIV medications (dolutegravir, elvitegravir, raltegravir), the antibiotic ceftriaxone, thyroid hormone (levothyroxine), a heart rhythm drug (sotalol), a calcium channel blocker (diltiazem), the psoriasis medication calcipotriene, or any other prescription medications. Calcium can interfere with how your body absorbs or uses these drugs.

No interactions are documented for the other ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with insufficient evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product is a calcium supplement with added proteins and growth factors from milk. It's worth considering if you need extra calcium and your doctor agrees — but if you take any HIV medications, thyroid hormone, heart drugs, or the antibiotic ceftriaxone, you'll need to time it carefully or avoid it altogether.

Run your exact medications through the checker below before you start, and let your pharmacist know if you're thinking about adding it to your routine.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bio-Gro Cookies N' Cream, straight from the product label.

Brand iSatori
Barcode (UPC) 883488003240
Net contents 4.16 Ounce(s); 118 Gram(s)
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 217090
Product type Other Combinations
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bio-Gro Cookies N' Cream by iSatori, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.96 Gram(s)
Maximum serving Sizes:
5.88 Gram(s)
Servings per container
60
UPC/BARCODE
883488003240
IngredientAmount% DV
Calories5 Calorie(s)--
Total Carbohydrates1 Gram(s)1%
Sugar0 Gram(s)--
Calcium20 mg2%
Growth Factors0 NP--
Immunoglobulins0 NP--
Lactoferrin0 NP--
Fibroblast-GF0 NP--
Custom Engineered Bio-Pro Bio-Active Peptides1.5 Gram(s)--
Proline Rich Peptides0 NP--

Other ingredients: Sucralose, Natural and Artificial flavors, Medium Chain Triglycerides, Sunflower Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Build muscle, recover faster and increase strength with Bio-Gro!

The first ever to utilize a highly concentrated form of BAPs, Bio-Gro signals the body to amplify the muscle protein synthesis process, and as our clinical studies have shown, help you recover faster, gain strength, and develop lean muscle more efficiently after intense workouts.

Instantized easy mixing

Sugar free Gluten free Stimulant free

Made in the USA from international and domestic ingredients

Protein synthesis amplifier

Recover faster Increase strength Build muscle

Formula

Bio-Gro utilizes Bio-Pro Bio-Active Peptides (BAPs) which are cleaved protein fragments extracted from the highest grade bovine colostrum.

Powered by Bio-Pro Bio-Active Peptides

Bio-Active Peptides

Cookies N' Cream Naturally & artificially flavored

Suggested/Recommended/Usage/Directions

To best amplify protein synthesis, use Bio-Gro twice daily as listed. Daily usage based on bodyweight <125Ibs 125-200Ibs >200Ibs 1 scoop AM 2 scoops AM 3 scoops 1 scoop PM 2 scoops PM 3 scoops

Directions For Use: As a dietary supplement, adults mix 1 serving of Bio-Gro twice daily in 3-4 oz of liquid and thoroughly agitate or blend, or mix in soft food (yogurt, oatmeal, etc.). Follow daily usage chart for optimal results and ensure one serving is taken before, during, or after your workout. Bio-Gro is available as an unflavored or flavored powder that can be taken anytime with out without food. To be used as part of a resistance training program.

Brand IP Statement(s)

2018 FitLife Brands, Inc.

Seals/Symbols

Made in the USA

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

General Statements

For scientific references, visit iSatori.com/BioGro

(Stock Symbol: FTLF)

FDA Statement of Identity

Dietary Supplement

Precautions

Notice: Tested athletes should check with governing body(s) before use.

Allergen Information: Contains milk product (colostrum).

Warning: Keep out of reach of children.

Do not use this product if you are pregnant, nursing, or contemplating pregnancy.

If you, or your doctor, have any questions about this product, please call 1-866-688-7679.

Not intended for individuals under the age of 18, unless instructed by a doctor.

Consult a physician or healthcare provider before using this or any other dietary supplement or starting any exercise program. Exposure to moisture and humidity may cause clumping but will not affect product efficacy. Do not use if packaging has been tampered with.

Storage

Store in a cool, dry place. Avoid excessive heat.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bio-Gro Cookies N' Cream by iSatori label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bio-Gro Cookies N' Cream label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bio-Gro Cookies N' Cream by iSatori

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size1.96 Gram(s) Dosage formPowder Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

0 Gram(s) per serving

Calcium

Interacts with
168 drugs
20 mg per serving

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet f...

Calcium monograph & interactions

Custom Engineered Bio-Pro Bio-Active Peptides

1.5 Gram(s) per serving Form: Colostrum

Other (inactive) ingredients: Sucralose, Natural and Artificial flavors, Medium Chain Triglycerides, Sunflower Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bio-Gro Cookies N' Cream by iSatori Drug Interactions

Want to check YOUR meds against Bio-Gro Cookies N' Cream?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
168Drugs
7 Major 143 Moderate 18 Minor

Ingredients driving the most interactions

Calcium 168

Individual Drug Interactions

The ingredients in Bio-Gro Cookies N' Cream interact with 168 drugs. Click any drug to see the details.

1 of the 7 ingredients in Bio-Gro Cookies N' Cream interact with drugs. Each result below shows which ingredient is responsible. Calcium

Each ingredient & the kinds of drugs it affects

For each ingredient in Bio-Gro Cookies N' Cream with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Calcium18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D
Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B
Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B
Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C
Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B
Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D
Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B
Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B
Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B
Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B
Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B
Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C
Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C
Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D
Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D
Calcium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bio-Gro Cookies N' Cream, from the product label.

iSatori

See all iSatori products
Name
iSatori A Division of FitLife Brands
Street Address
5214 South 136th Street
City
Omaha
State
NE
ZipCode
68137
Phone Number
1-866-688-7679
Web Address
www.iSatori.com
Pharmacist Counseling Corner

Bio-Gro Cookies N' Cream by iSatori: Common Questions

Does Bio-Gro Cookies N' Cream by iSatori interact with any medications?
Yes. Based on its ingredients, Bio-Gro Cookies N' Cream has a known interaction with 168 medications, including 7 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bio-Gro Cookies N' Cream contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What does the calcium in this product do?
Calcium strengthens bones and teeth, helps muscles contract, and keeps your nerves working properly. It's effective for treating low calcium levels, upset stomach, and high potassium, and is likely effective for preventing and treating osteoporosis.
What are Growth Factors, Immunoglobulins, and Lactoferrin in this powder for?
These are milk-derived proteins and growth compounds meant to support your immune system and possibly wound healing. Lactoferrin shows some promise for sepsis and iron deficiency in pregnancy, but evidence for the others is limited or not yet established.
What side effects should I expect?
The most common are belching, constipation, diarrhea, gas, and mild stomach upset from the calcium. Lactoferrin at typical doses is well tolerated, though some people report diarrhea or constipation. High doses of lactoferrin (7.2 grams daily) increase the risk of side effects like fatigue and loss of appetite.
Is it safe to take while I'm pregnant or breastfeeding?
Calcium at recommended amounts is considered likely safe in pregnancy and lactation — in fact, you need adequate calcium in both. Lactoferrin and Proline Rich Peptides don't have enough safety data during pregnancy or breastfeeding, so talk with your doctor or midwife before using them if you're pregnant or nursing.
Does this product have fillers?
Yes — it contains sucralose (sweetener), natural and artificial flavors, medium chain triglycerides (fat), and sunflower lecithin (emulsifier) to make it mix smoothly and taste like cookies and cream. These are inactive ingredients, not the active ones.
Can I take this with my thyroid medication?
Calcium can reduce how well your body absorbs levothyroxine (Synthroid and others), so you'll need to take them at least 4 hours apart. Check with your pharmacist about the exact timing that works for your dose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bio-Gro Cookies N' Cream label
Go deeper

The Full Monographs Behind Bio-Gro Cookies N' Cream’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Calcium

Interacts with 168 drugs

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet falls short. Most people do best getting...

Read the full Calcium monograph → Herb & supplement monograph

Lactoferrin

Lactoferrin is an iron-binding protein found naturally in milk and other body fluids, and supplements are usually made from cow's milk or rice. It is being studied for immune support, iron l...

Read the full Lactoferrin monograph → Herb & supplement monograph

Proline

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of collagen, but strong human evidence that...

Read the full Proline monograph →
Sources

Sources & How We Checked

Bio-Gro Cookies N' Cream's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 72 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Calcium 62 references
  1. Shils M, Olson A, Shike M. Modern Nutrition in Health and Disease. 8th ed. Philadelphia, PA: Lea and Febiger, 1994.
  2. Hernandez-Avila M, Gonzalez-Cossio T, Hernandez-Avila JE, et al. Dietary calcium supplements to lower blood lead levels in lactating women: a randomized placebo-controlled trial. Epidemiology 2003;14:206-12.. PubMed
  3. Thys-Jacobs S, Ceccarelli S, Bierman A, et al. Calcium supplementation in premenstrual syndrome: a randomized crossover trial. J Gen Intern Med 1989;4:183-9. PubMed
  4. Maton PN, Burton ME. Antacids revisited: a review of their clinical pharmacology and recommended therapeutic use. Drugs 1999;57:855-70.
  5. Clemens JD, Feinstein AR. Calcium carbonate and constipation: a historical review of medical mythopoeia. Gastroenterology 1977;72:957-61. DOI
  6. Saunders D, Sillery J, Chapman R. Effect of calcium carbonate and aluminum hydroxide on human intestinal function. Dig Dis Sci 1988;33:409-13. PubMed
  7. Friedman PA, Bushinsky DA. Diuretic effects on calcium metabolism. Semin Nephrol 1999;19:551-6.
  8. Koo WK, Walters JC, Esterlitz J, et al. Maternal calcium supplementation and fetal bone mineralization. Obstet Gynecol 1999;94:577-82. DOI
  9. Raman L, Rajalakshmi K, Krishnamachari KAVR, et al. Effect of calcium supplementation to undernourished mothers during pregnancy on the bone density of the neonates. Am J Clin Nutr 1978; 31:466-9. DOI
  10. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  11. Chan JM, Giovannucci E, Andersson SO, et al. Dairy products, calcium, phosphorous, vitamin D, and risk of prostate cancer. Cancer Causes Control 1998;9:559-66.
  12. Butner LE, Fulco PP, Feldman G, et al. Calcium carbonate-induced hypothyroidism. Ann Intern Med 2000:132:595. PubMed
  13. Schneyer CR. Calcium carbonate and reduction of levothyroxine efficacy. JAMA 1998;279:750. PubMed
  14. Moser LR, Smythe MA, Tisdale JE. The use of calcium salts in the prevention and management of verapamil-induced hypotension. Ann Pharmacother 2000;34:622-9. PubMed
  15. Singh N, Singh PN, Hershman JM. Effect of calcium carbonate on the absorption of levothyroxine. JAMA 2000;283:2822-5. PubMed
  16. Kahela P, Anttila M, Tikkanen R, Sundquist H. Effect of food, food constituents and fluid volume on the bioavailability of sotalol. Acta Pharmacol Toxicol (Copenh) 1979;44:7-12.. PubMed
  17. Pletz MW, Petzold P, Allen A, et al. Effect of calcium carbonate on bioavailability of orally administered gemifloxacin. Antimicrob Agents Chemother 2003;47:2158-60.. PubMed
  18. Bar-Or D, Yoel G. Calcium and calciferol antagonize effect of verapamil in atrial fibrillation. Br Med J 1981;282:1585-6.
  19. Decktor DL, Robinson M, Maton PN, et al. Effects of aluminum/magnesium hydroxide and calcium carbonate on esophageal and gastric pH in subjects with heartburn. Am J Ther 1995;2:546-52. PubMed
  20. Simoneau G. Absence of rebound effect with calcium carbonate. Eur J Drug Metab Pharmacokinet 1996;21:351-7. PubMed
  21. Peters ML, Leonard M, Licata AA. Role of alendronate and risedronate in preventing and treating osteoporosis. Cleve Clin J Med 2001;68:945-51. PubMed
  22. Bourke JF, Mumford R, Whittaker P, et al. The effects of topical calcipotriol on systemic calcium homeostasis in patients with chronic plaque psoriasis. J Am Acad Dermatol 1997;37:929-34.
  23. Gueguen L, Pointillart A. The bioavailability of dietary calcium. J Am Coll Nutr 2000;19:119s-136s. PubMed
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See these in context on the Calcium monograph →

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See these in context on the Lactoferrin monograph →

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See these in context on the Proline monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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