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Dietary supplement

BioticSticks Mixed Berry Flavor Ingredients & Drug Interactions

by Arbonne

BioticSticks Mixed Berry Flavor label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking BioticSticks Mixed Berry Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

BioticSticks Mixed Berry Flavor is a dietary supplement by Arbonne with 1 active ingredient. Its ingredients are commonly taken for digestive health and bloating, diarrhea support, immune support.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bacillus subtilis DE-111. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against BioticSticks Mixed Berry Flavor by Arbonne

Ask about any prescription or over-the-counter medication and we check it for interactions with BioticSticks Mixed Berry Flavor by Arbonne — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of BioticSticks Mixed Berry Flavor by Arbonne

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

BioticSticks Mixed Berry Flavor contains one active ingredient: Bacillus subtilis DE-111, a live probiotic bacterium. The remaining ingredients — xylitol, natural flavors, citric acid, malic acid, and silicon dioxide — are inactive fillers and flavorings that make up the powder base.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Digestive health and gut microbiome balance.
  • We looked for evidence on: Antibiotic-associated diarrhea, Clostridioides difficile infection, Constipation, Diarrhea, Dyspepsia, Flatulence — and 4 related terms.
  • The strongest evidence on file: Bacillus Subtilis is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Bacillus Subtilis is rated "Insufficient Reliable Evidence To Rate" for Constipation, Diarrhea, Dyspepsia, Flatulence, and more.

The evidence for Bacillus subtilis DE-111 is mixed. It's rated possibly effective for antibiotic-associated diarrhea (loose stools that happen after taking antibiotics).

For athletic performance, constipation, eczema, diabetes, and cirrhosis, the evidence isn't established — there's simply not enough reliable data yet to say whether it works.

The evidence, ingredient by ingredient Bacillus Subtilis

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bacillus subtilis DE-111 is generally well tolerated in healthy adults, though quality and safety vary between products and strains. One person reported a headache in a clinical trial, and diarrhea has been reported rarely.

However, the safety data is limited. There have been cases of serious infection (bloodstream and brain infection) in people who frequently consumed fermented soy products containing a related Bacillus subtilis strain, usually in those with weakened immune systems from age, diabetes, kidney disease, or immunosuppressive treatment.

Because the safety information is incomplete, talk with your doctor before starting this supplement, especially if you have a weakened immune system. We hold no pregnancy or breastfeeding safety data for this ingredient.

Side effects, ingredient by ingredient Bacillus Subtilis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bacillus Subtilis.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check any antibiotic drugs you're on with your doctor or pharmacist. Timing matters: antibiotics taken at the same time as this probiotic may reduce how well the probiotic works.

Altogether, these interactions span 182 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic may help with antibiotic-associated diarrhea, but the evidence for other uses isn't there yet. If you're healthy and don't take antibiotics regularly, it's generally well tolerated — though quality varies by brand.

If you have a weakened immune system, take antibiotics often, or are pregnant or breastfeeding, check with your doctor or pharmacist before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BioticSticks Mixed Berry Flavor, straight from the product label.

Brand Arbonne
Net contents 30 Stick Pack(s); 1 Ounce(s); 30 Gram(s)
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 303391
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BioticSticks Mixed Berry Flavor by Arbonne, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Stick Pack(s)
Maximum serving Sizes:
1 Stick Pack(s)
Servings per container
30
IngredientAmount% DV
Total Carbohydrates1 Gram(s)1%
Bacillus subtilis DE-1113 mg--

Other ingredients: Xylitol, Natural Flavors, Citric Acid, Malic Acid, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Notice: pregnant or lactating women and people with known medical conditions should consult with a physician prior to taking supplements.

Not recommended for those with swallowing difficulties due to choking hazard. Do not use if outer seal is broken or missing or if packet is torn or open.

Keep out of reach of children.

Keep in a cool, dry place.

Do not exceed the recommended daily intake of one stick pack per day.

Made in a facility that processes wheat, soybeans, milk, and eggs.

Formulation

Manufactured in USA from imported materials.

Helps support gut health and microbiome diversity

100% Vegan

Gluten-free

Seals/Symbols

Certified B Corporation

General Statements

A force for good for people and planet Paper carton

30 stick packs - 0.03 oz. /1 g each

Formula

Fast melt probiotic

Mixed Berry Flavor + other natural flavors

Ages 4 and up

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

Arbonne Mind. Body. Skin.

DE111 is a registered trademark of Deerland Probiotics & enzymes, Inc.

Suggested/Recommended/Usage/Directions

Directions: ages 4 and up take one stick pack daily. Pour stick pack contents into mouth. Powder will begin to dissolve, swallow contents. No water is needed. Can also be added to cold food or drink.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

BioticSticks Mixed Berry Flavor by Arbonne label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

BioticSticks Mixed Berry Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in BioticSticks Mixed Berry Flavor by Arbonne

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Stick Pack(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Bacillus subtilis DE-111

Interacts with
182 drugs
3 mg per serving

Bacillus subtilis is a spore-forming probiotic bacterium found in soil and some fermented foods, and it is used mainly to support gut health and diges...

Bacillus subtilis DE-111 monograph & interactions

Other (inactive) ingredients: Xylitol, Natural Flavors, Citric Acid, Malic Acid, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

BioticSticks Mixed Berry Flavor by Arbonne Drug Interactions

Want to check YOUR meds against BioticSticks Mixed Berry Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Bacillus subtilis DE-111 182

Individual Drug Interactions

The ingredients in BioticSticks Mixed Berry Flavor interact with 182 drugs. Click any drug to see the details.

1 of the 1 ingredient in BioticSticks Mixed Berry Flavor interact with drugs. Each result below shows which ingredient is responsible. Bacillus subtilis DE-111

Each ingredient & the kinds of drugs it affects

For each ingredient in BioticSticks Mixed Berry Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bacillus subtilis DE-1111 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bacillus subtilis with antibiotic drugs might decrease the effectiveness of B. subtilis.
Since B. subtilis preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. subtilis preparations by at least 2 hours.

Likelihood Probable Evidence D
Bacillus subtilis DE-111 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for BioticSticks Mixed Berry Flavor, from the product label.

Arbonne

See all Arbonne products
Name
Arbonne International, LLC
Street Address
9400 Jeronimo Road
City
Irvine
State
CA
ZipCode
92618
Phone Number
1.800.272.6663
Web Address
arbonne.com
Pharmacist Counseling Corner

BioticSticks Mixed Berry Flavor by Arbonne: Common Questions

Does BioticSticks Mixed Berry Flavor by Arbonne interact with any medications?
Yes. Based on its ingredients, BioticSticks Mixed Berry Flavor has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
BioticSticks Mixed Berry Flavor contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my diarrhea after I finish antibiotics?
Possibly. Bacillus subtilis DE-111 is rated possibly effective for antibiotic-associated diarrhea. That said, talk with your doctor before starting — the timing matters, especially since antibiotics can interfere with the probiotic if you take them together.
Is this safe if I have a weakened immune system?
Be cautious. There have been rare cases of serious infection in people with weakened immunity who consumed fermented foods containing a related Bacillus subtilis strain. Talk with your doctor before using this product if you have diabetes, kidney disease, are on immunosuppressive medication, or are dealing with a chronic illness.
Can I take this while I'm on antibiotics?
Not at the same time. Taking them together may kill off the live organisms and make the probiotic less effective. Your doctor or pharmacist can help you space out the timing — usually a few hours apart works well.
What does Bacillus subtilis DE-111 actually do?
It's a live probiotic bacterium meant to support your digestive health. The evidence is strongest for antibiotic-associated diarrhea. For other uses like constipation, athletic performance, or eczema, we don't have enough reliable data yet.
Is there safety data for pregnancy or breastfeeding?
We don't hold pregnancy or breastfeeding safety data for this ingredient. If you're pregnant or breastfeeding, talk with your doctor or pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if BioticSticks Mixed Berry Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BioticSticks Mixed Berry Flavor label
Go deeper

The Full Monographs Behind BioticSticks Mixed Berry Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bacillus Subtilis

Interacts with 182 drugs

Bacillus subtilis is a spore-forming probiotic bacterium found in soil and some fermented foods, and it is used mainly to support gut health and digestion. Early research is promising for ce...

Read the full Bacillus Subtilis monograph →
Sources

Sources & How We Checked

BioticSticks Mixed Berry Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 10 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bacillus Subtilis 10 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Lampropoulos PK, Gkentzi D, Tzifas S, Dimitriou G. Neonatal sepsis due to Bacillus subtilis. Cureus 2021;13(9):e17692. PubMed
  3. La Jeon Y, Yang JJ, Kim MJ, et al. Combined Bacillus licheniformis and Bacillus subtilis infection in a patient with oesophageal perforation. J Med Microbiol 2012;61(Pt 12):1766-1769. PubMed
  4. Wallet F, Crunelle V, Roussel-Delvallez M, Fruchart A, Saunier P, Courcol RJ. Bacillus subtilis as a cause of cholangitis in polycystic kidney and liver disease. Am J Gastroenterol 1996;91(7):1477-8.
  5. Velasco E, Martins CA, Tabak D, Bouzas LF. "Bacillus subtilis" infection in a patient submitted to a bone marrow transplantation. Rev Paul Med 1992;110(3):116-7.
  6. Kato A, Yoshifuji A, Komori K, et al. A case of Bacillus subtilis var. natto bacteremia caused by ingestion of natto during COVID-19 treatment in a maintenance hemodialysis patient with multiple myeloma. J Infect Chemother 2022;28(8):1212-1215. PubMed
  7. Freedman KE, Hill JL, Wei Y, et al. Examining the gastrointestinal and immunomodulatory effects of the novel probiotic Bacillus subtilis DE111. Int J Mol Sci 2021;22(5):2453. PubMed
  8. Lefevre M, Racedo SM, Denayrolles M, et al. Safety assessment of Bacillus subtilis CU1 for use as a probiotic in humans. Regul Toxicol Pharmacol 2017;83:54-65. PubMed
  9. Hanifi A, Culpepper T, Mai V, et al. Evaluation of Bacillus subtilis R0179 on gastrointestinal viability and general wellness: a randomised, double-blind, placebo-controlled trial in healthy adults. Benef Microbes 2015;6(1):19-27. PubMed
  10. Tokano M, Tarumoto N, Imai K, et al. A case of bacterial meningitis caused by Bacillus subtilis var. natto. Intern Med. 2022. Epub ahead of print.

See these in context on the Bacillus Subtilis monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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