Bitter Melon Alcohol Free Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Bitter Melon Alcohol Free against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Bitter Melon Alcohol Free is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, diabetes, digestive complaints.Based on those ingredients, 283 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bitter Melon Fruit Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Bitter Melon Alcohol Free by Herbal Terra
Ask about any prescription or over-the-counter medication and we check it for interactions with Bitter Melon Alcohol Free by Herbal Terra — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Bitter Melon Alcohol Free by Herbal Terra
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
The active ingredient is bitter melon fruit extract, dry, the only active ingredient listed for this product. Bitter melon is a fruit that has been used traditionally, and its extract is the component behind the interactions and effects discussed on this page.
The other listed ingredients, glycerin and water, are inactive ingredients. They are not active ingredients, and they are included in the formula for their role in the liquid itself.
Does it work?
Couldn't assess
Bitter melon has been reviewed for several uses, including amenorrhea (missed periods), athletic performance, liver disease, constipation, diabetes, and dyspepsia (indigestion). For each of these, the reliable evidence we hold is rated insufficient to rate, so we cannot say whether it works for any of them.
If you are considering this product for one of these purposes, talk with your own doctor or pharmacist about what is known and what other options might fit your situation.
How safe is it?
Well-documented data
Bitter melon is generally well tolerated orally, but the most common side effects are stomach-related, including heartburn, nausea, vomiting, diarrhea, constipation, flatulence, and abdominal discomfort. Dizziness, fatigue, and headache have also been reported.
Our safety notes say supplement amounts may lower blood sugar and cause stomach upset. A rare but serious effect listed is hypoglycemic coma and seizures, particularly in children.
In one case report, a patient developed acute interstitial nephritis (kidney inflammation) after months of taking bitter melon extract for diabetes, and kidney function returned to baseline after the extract was stopped and treatment was given. Our pregnancy and breastfeeding information is limited: safety notes say bitter melon is traditionally avoided in pregnancy, while the lactation entry contains no rating, and there is not enough reliable safety information for breastfeeding.
Please talk with your own doctor or pharmacist for personalized advice.
Meds to double-check
Moderate interaction found
Double-check antidiabetes drugs first, since bitter melon may add to their blood-sugar-lowering effect and raise the risk of low blood sugar. Next, check P-glycoprotein substrates (drugs cleared by the P-gp gut pump) and pazopanib, a kidney cancer medicine, both rated Moderate.
For any medication you take, use the search tool on this page and confirm with your own doctor or pharmacist before combining it with this product.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Bitter melon may be of interest to adults who are looking into it for a purpose on this page and who take no medications that interact with it. People who take antidiabetes drugs, P-glycoprotein substrates, or pazopanib should be especially careful.
Anyone who is pregnant, breastfeeding, or planning a pregnancy should talk it over with their own doctor or pharmacist before using it.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Bitter Melon Alcohol Free, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 7386004836948 |
| Net contents | 2 Fluid Ounce(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2024 |
| DSLD ID | 323968 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Bitter Melon Alcohol Free by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Bitter Melon Fruit Extract, Dry | 1156 mg | -- |
Other ingredients: Glycerin, Water
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.
Precautions
We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!
Do not use if you are allergic to any ingredients.
Storage
Store in a cool, dry, dark place.
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
Formulation
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
Sugar free
Expertly extracted 100% natural Premium product
No alcohol (ethyl), artificial ingredients, color additives, fillers or binders.
Natural Gluten free
Formula
Momordica charantia
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
Made in USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Bitter Melon Alcohol Free by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Bitter Melon Alcohol Free by Herbal Terra
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Bitter Melon Fruit Extract, Dry
Interacts with283 drugs
Bitter melon is a tropical fruit eaten as food and used in traditional medicine, most often for blood sugar control. While some small studies hint it...
Bitter Melon Fruit Extract, Dry monograph & interactionsOther (inactive) ingredients: Glycerin, Water. These complete the product’s ingredient list but are not active constituents.
Bitter Melon Alcohol Free by Herbal Terra Drug Interactions
HelloPharmacist Interaction Report
Bitter Melon Alcohol Free from Herbal Terra has documented interactions with medications, all coming from its one active ingredient, bitter melon fruit extract.
The interaction we hold for antidiabetes drugs (medicines that lower blood sugar) is rated Moderate. Bitter melon also lowers blood sugar, so taking both may increase the risk of low blood sugar (hypoglycemia).
Read the full breakdown — every affected drug type, severity by severity
Bitter melon may also raise levels of P-glycoprotein substrates, which are drugs cleared by a gut pump called P-glycoprotein (P-gp). This is rated Moderate and is theoretical, based on lab research.
It may also raise levels of pazopanib, a kidney cancer medicine, potentially increasing side effects, also rated Moderate. In one case, a patient taking pazopanib developed signs consistent with acute pancreatitis (inflammation of the pancreas) after drinking bitter melon juice.
Altogether, these interactions span 283 individual medications.
Because every checked ingredient in this product has documented interactions, the search tool on this page is the best way to check your exact medications. Talk with your own doctor or pharmacist before you start, stop, or combine this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Bitter Melon Alcohol Free?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Bitter Melon Alcohol Free interact with 283 drugs. Click any drug to see the details.
1 of the 1 ingredient in Bitter Melon Alcohol Free interact with drugs. Each result below shows which ingredient is responsible. Bitter Melon Fruit Extract, Dry
AcalabrutinibCalquence
How Acalabrutinib interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Bitter Melon Fruit Extract, Dry + Acarbose interactionAcetohexamideDymelor
How Acetohexamide interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Bitter Melon Fruit Extract, Dry + Acetohexamide interactionAfatinib DimaleateGilotrif
How Afatinib Dimaleate interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Afatinib Dimaleate interactionAlbiglutideTanzeum
How Albiglutide interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Bitter Melon Fruit Extract, Dry + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Bitter Melon Fruit Extract, Dry + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Bitter Melon Fruit Extract, Dry + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Bitter Melon Fruit Extract, Dry + Alogliptin, Pioglitazone interactionAlvimopanEntereg
How Alvimopan interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Alvimopan interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Ambrisentan interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Amphotericin, Tetracycline interactionAmprenavirAgenerase
How Amprenavir interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Amprenavir interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates, Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionApixabanEliquis
How Apixaban interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Apixaban interactionApomorphineAPO-go, APO-go Pen, APO-go PFS, Apokyn, Uprima
How Apomorphine interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Apomorphine interactionApomorphine HydrochlorideKynmobi
How Apomorphine Hydrochloride interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Apomorphine Hydrochloride interactionApremilastOtezla
How Apremilast interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Apremilast interactionArmodafinilNuvigil
How Armodafinil interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Armodafinil interactionAtogepantQulipta
How Atogepant interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Atogepant interactionAtropine, Morphine SulfateAtropine, Morphine Sulfate
How Atropine, Morphine Sulfate interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Atropine, Morphine Sulfate interactionAvatrombopag MaleateDoptelet
How Avatrombopag Maleate interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Avatrombopag Maleate interactionBazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Bazedoxifene Acetate, Conjugated Estrogens interactionBeclometasone DipropionateBecotide
How Beclometasone Dipropionate interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Beclometasone Dipropionate interactionBeclomethasoneBeclovent, Vanceril
How Beclomethasone interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Beclomethasone interactionBeclomethasone DipropionateQNASL, Qvar
How Beclomethasone Dipropionate interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Beclomethasone Dipropionate interactionBelinostatBeleodaq
How Belinostat interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Belinostat interactionBerotralstat HydrochlorideOrladeyo
How Berotralstat Hydrochloride interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Berotralstat Hydrochloride interactionBetamethasoneCelestone, Diprolene AF, Diprosone
How Betamethasone interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Betamethasone interactionBetamethasone DipropionateSernivo
How Betamethasone Dipropionate interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Betamethasone Dipropionate interactionBetamethasone Dipropionate, CalcipotrieneEnstilar, Wynzora
How Betamethasone Dipropionate, Calcipotriene interacts with Bitter Melon Alcohol Free — through 1 ingredient. Tap an ingredient for the detail:
Bitter Melon Fruit Extract, DryP-glycoprotein Substrates Moderate
Interaction Summary
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Read the full Bitter Melon Fruit Extract, Dry + Betamethasone Dipropionate, Calcipotriene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Bitter Melon Alcohol Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Bitter Melon Fruit Extract, Dry
Antidiabetes Drugs
Taking bitter melon with antidiabetes drugs might increase the risk of hypoglycemia.
Bitter melon can lower blood glucose levels and might have additive effects when used with antidiabetes drugs. This might increase the risk of hypoglycemia in some patients. Monitor blood glucose levels closely.
P-Glycoprotein Substrates
Theoretically, bitter melon might increase levels of P-glycoprotein substrates.
Bitter melon might inhibit the p-glycoprotein (P-gp) intestinal pump and increase intracellular levels of P-gp substrates. In vitro research in intestinal cells shows that 1-monopalmitin, a constituent of bitter melon, increases levels of daunomycin, a P-gp substrate. Additionally, drinking bitter melon juice has been associated with a case of acute pancreatitis in a patient who had been taking pazopanib, a P-gp substrate, for 8 years. Researchers theorize that inhibition of P-gp led to increased levels of pazopanib, resulting in pazopanib-induced pancreatitis.
Pazopanib (Votrient)
Theoretically, bitter melon might increase levels of pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 8 years for renal cell carcinoma experienced signs and symptoms consistent with acute pancreatitis 4 days after drinking bitter melon juice at a dose of 100-150 mL daily. The patient's symptoms, amylase levels, and lipase levels improved upon discontinuation of bitter melon and pazopanib. Pazopanib treatment was re-initiated with no further evidence of pancreatitis. Researchers theorize that inhibition of P-glycoprotein by bitter melon led to increased levels of pazopanib, a P-glycoprotein substrate, resulting in pazopanib-induced pancreatitis.
Brand information
Manufacturer and brand details for Bitter Melon Alcohol Free, from the product label.
Herbal Terra
See all Herbal Terra products- Name
- Herbal Terra LLC
- Phone Number
- +18083857868
- Web Address
- herbalterra.com
Bitter Melon Alcohol Free by Herbal Terra: Common Questions
Does Bitter Melon Alcohol Free by Herbal Terra interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is bitter melon effective for diabetes?
What are the common side effects?
Can I use this while pregnant?
Is it okay while breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Bitter Melon Alcohol Free is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Bitter Melon Alcohol Free’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Bitter Melon Alcohol Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 18 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Bitter Melon 18 references
- Leatherdale B, Panesar RK, Singh G, et al. Improvement in glucose tolerance due to Momordica charantia. Br Med J (Clin Res Ed) 1981;282:1823-4.
- Welihinda J, et al. Effect of Momordica charantia on the glucose tolerance in maturity onset diabetes. J Ethnopharmacol 1986;17:277-82. PubMed
- Srivastava Y, Venkatakrishna-Bhatt H, Verma Y, et al. Antidiabetic and adaptogenic properties of Momordica charantia extract: An experimental and clinical evaluation. Phytother Res 1993;7:285-9.
- Baldwa VS, Bhandari CM, Pangaria A, Goyal RK. Clinical trial in patients with diabetes mellitus of an insulin-like compound obtained from plant sources. Ups J Med Sci 1977;82:39-41. PubMed
- Aslam M, Stockley IH. Interaction between curry ingredient (karela) and drug (chlorpropamide). Lancet 1979:1:607. PubMed
- Ahmad N, Hassan MR, Halder H, Bennoor KS. Effect of Momordica charantia (Karolla) extracts on fasting and postprandial serum glucose levels in NIDDM patients (abstract). Bangladesh Med Res Counc Bull 1999;25:11-3.
- Basch E, Gabardi S, Ulbricht C. Bitter melon (Momordica charantia): a review of efficacy and safety. Am J Health Syst Pharm 2003;60:356-9. PubMed
- Yin RV, Lee NC, Hirpara H, Phung OJ. T. The effect of bitter melon (Mormordica charantia) in patients with diabetes mellitus: s systematic review and meta-analysis. Nutr Diabetes. 2014;4:e145.
- Rahman IU, Khan RU, Rahman KU, Bashir M. Lower hypoglycemic but higher antiatherogenic effects of bitter melon than glibenclamide in type 2 diabetic patients. Nutr J. 2015;14:13. PubMed
- Alam MA, Uddin R, Subhan N, Rahman MM, Jain P, Reza HM. Beneficial role of bitter melon supplementation in obesity and related complications in metabolic syndrome. J Lipids. 2015;2015:496169. PubMed
- Konishi T, Satsu H, Hatsugai Y, et al. Inhibitory effect of a bitter melon extract on the P-glycoprotein activity in intestinal Caco-2 cells. Br J Pharmacol. 2004;143(3):379-87. PubMed
- Peter EL, Kasali FM, Deyno S, et al. Momordica charantia L. lowers elevated glycaemia in type 2 diabetes mellitus patients: Systematic review and meta-analysis. J Ethnopharmacol. 2019;231:311-24. doi: 10.1016/j.jep.2018.10.033. PubMed
- Cortez-Navarrete M, Martínez-Abundis E, Pérez-Rubio KG, González-Ortiz M, Méndez-Del Villar M. Momordica charantia administration improves insulin secretion in type 2 diabetes mellitus. J Med Food. 2018;21(7):672-7. doi: 10.108
- Kim SK, Jung J, Jung JH, et al. Hypoglycemic efficacy and safety of Momordica charantia (bitter melon) in patients with type 2 diabetes mellitus. Complement Ther Med. 2020 Aug;52:102524. doi: 10.1016/j.ctim.2020.102524. PubMed
- Unsal O, Sütcüoglu O, Yazici O. Dangerous interaction of bitter melon (Momordica charantia) with pazopanib: a case of acute pancreatitis. J Oncol Pharm Pract 2022;28(2):486-8.
- Bae W, Kim S, Choi J, et al. Acute interstitial nephritis associated with ingesting a Momordica charantia extract: a case report. Medicine (Baltimore) 2021;100(27):e26606. PubMed
- Chattopadhyay K, Wang H, Kaur J, et al. Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Front Pharmacol. 2022;13:821810. Published 2022 Jun 8. PubMed
- Kim B, Lee HS, Kim HJ, et al. Momordica charantia (bitter melon) efficacy and safety on glucose metabolism in Korean prediabetes participants: a 12-week, randomized clinical study. Food Sci Biotechnol 2022;32(5):697-704. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC