Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Bloat Less Ingredients & Drug Interactions

by Applied Nutrition

Bloat Less label
See full label image
Softgel Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bloat Less against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bloat Less is a dietary supplement by Applied Nutrition with 2 active ingredients. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Bloat Less by Applied Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Bloat Less by Applied Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Bloat Less by Applied Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Bloat Less contains 2 active ingredients. Potassium is a mineral your body needs for nerve and muscle function, including heart rhythm.

The Bloat-Less Blend is the second active ingredient, but we have no details on file about what it contains or how it works. The capsule itself is made from gelatin and includes soy oil, beeswax, soy lecithin, glycerin, and colorants — these are inactive ingredients (fillers and binders that make the capsule function).

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: support the body's natural water balance.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We hold no effectiveness data in our records for either active ingredient in this product.

The evidence, ingredient by ingredient Potassium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Potassium from food is safe, but supplements can build up to dangerous levels in some people, especially those with kidney problems — high blood potassium can cause heart rhythm problems, weakness, or confusion. Most people tolerate oral potassium okay, though a small number experience belly pain, belching, diarrhea, gas, nausea, or vomiting.

For pregnancy and breastfeeding, the data shows potassium from food is fine, but if you're thinking about using this supplement during pregnancy or while breastfeeding, talk with your doctor or pharmacist first. They can tell you whether it's right for your situation.

Side effects, ingredient by ingredient Potassium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before taking this product if you use potassium-sparing diuretics, ACE inhibitors, or ARBs — all carry a Moderate risk of dangerously high blood potassium when combined with potassium supplements. Altogether, these interactions span 62 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product is mainly a concern if you take blood-pressure medication or water pills — potassium supplements don't mix well with those, and they can be risky if you have kidney disease. If you don't take any of those drugs and your kidneys are healthy, a small potassium supplement from food is normal, but check with your own doctor or pharmacist before adding a supplement to be sure it fits your health picture.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 1, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bloat Less, straight from the product label.

Brand Applied Nutrition
Net contents 28 Liquid Soft-Gel
Market status On market
Date entered into DSLD Oct 1, 2012
DSLD ID 13308
Product type Botanical With Nutrients
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bloat Less by Applied Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
14
IngredientAmount% DV
Potassium100 mg3%
Bloat-Less Blend770 mg--

Other ingredients: Soy bean Oil, Gelatin, purified Water, Beeswax, Soy Lecithin, Glycerin, Silicon Dioxide, Titanium Dioxide, Sodium Copper Chlorophyllins

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

BOTTLE 4: 28 LIQUID SOFT-GELS

PRODUCT 4: BLOAT-LESS Fast-acting liquid soft-gels to support the body’s natural water balance.

BLOAT-LESS BOTTLE 4: Supports the Body's Natural Water Balance

PRODUCT 4: BLOAT-LESS

A reduced calorie diet & exercise plan, plus tips on continued weight support, visit: www.AppliedNutrition.com/deplan

The Bootcamp Mission: To help you achieve a healthier body weight in two weeks, so you look and feel great!

How It Works: This intensive diet system supplies four powerful products that, when used in combination with a reduced calorie diet and exercise plan, can help to maximize your weight loss efforts.

4-in-ONE DOCTOR-DEVELOPED HARDCORE DIET!

This program requires that you follow a reduced calorie diet & exercise plan.

Take the 2-Week Challenge! Are you looking to lose some weight, but frustrated with your results? Are you trying to get back into those skinny jeans or to fit into that new dress for a big event? Or would you like to feel more confident while wearing less?

“Stick with it for two weeks… and you will find that the results are worth the effort!”

Suggested/Recommended/Usage/Directions

Product 4: Bloat-Less: (Adult) Take two (2) liquid soft-gels daily with water.

Notice: For best results we recommend limiting the consumption of additional caffeine while using this product (e.g. less than three 8 ounce cups of coffee per day).

Precautions

Not intended for use by persons under 18 years of age.

KEEP OUT OF REACH OF CHILDREN.

KEEP OUT OF REACH OF CHILDREN.

Not intended for use by persons under 18 years of age.

Do not use if you are pregnant or nursing.

Usage Warnings: Do not use if safety seal is broken. Do not exceed recommended daily intake.

This product contains caffeine and may affect blood pressure and/or heart conditions. If you are under the care of a physician, please consult your physician before using this product.

Consult your physician before using this product if you are taking heart medications, diuretics or have a medical condition.

Do not use if you have an intestinal obstruction, hemorrhoids or other intestinal/digestive disorder.

WARNING: (State of California Prop 65) This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

2-Week Bootcamp Extreme Diet(TM) is a doctor-developed system that is specially designed to give you the hardcore results that you are looking for. This intense multi-product & diet program is unlike anything you have tried before.

Applied Nutrition(R) is committed to developing science-based products that exceed the highest standards for quality and purity. As a leader in innovation, we continuously strive to bring forward new ideas and groundbreaking formulas that enhance health and well-being. To view our entire line of products, please visit us online at: www.AppliedNutrition.com

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Contains: Soy

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bloat Less by Applied Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bloat Less label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bloat Less by Applied Nutrition

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container14 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Potassium

Interacts with
62 drugs
100 mg per serving Form: Potassium Citrate

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium monograph & interactions

Bloat-Less Blend

770 mg per serving Form: Buchu (Agathosma betulina) powder, Cranberry (Vaccinium macrocarpon) powder, Dandelion (Taraxacum officinale) powder, Grape Seed extract, Hibiscus (Hibiscus sabdariffa) extract, Juniper Berry powder, Parsley extract, Uva-ursi extract

Other (inactive) ingredients: Soy bean Oil, Gelatin, Purified Water, Beeswax, Soy Lecithin, Glycerin, Silicon Dioxide, Titanium Dioxide, Sodium Copper Chlorophyllins. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bloat Less by Applied Nutrition Drug Interactions

Want to check YOUR meds against Bloat Less?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Potassium 62

Individual Drug Interactions

The ingredients in Bloat Less interact with 62 drugs. Click any drug to see the details.

1 of the 2 ingredients in Bloat Less interact with drugs. Each result below shows which ingredient is responsible. Potassium

Each ingredient & the kinds of drugs it affects

For each ingredient in Bloat Less with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bloat Less, from the product label.

Applied Nutrition

See all Applied Nutrition products
Name
Applied Nutrition(R)
Street Address
P.O. Box 66457
City
Los Angeles
State
CA
ZipCode
90066
Pharmacist Counseling Corner

Bloat Less by Applied Nutrition: Common Questions

Does Bloat Less by Applied Nutrition interact with any medications?
Yes. Based on its ingredients, Bloat Less has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bloat Less contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is potassium and why is it in this product?
Potassium is a mineral your body uses for nerve signals, muscle function, and keeping your heart beating steadily. This product includes it as an active ingredient, though we don't have details on what the other active ingredient (Bloat-Less Blend) is supposed to do.
Can I take this if I have kidney disease?
No — potassium supplements can be dangerous if your kidneys don't work normally, because they can't clear excess potassium and it builds up in your blood. Talk with your doctor or pharmacist before taking any potassium supplement if you have or suspect kidney disease.
What are the most common side effects?
Most people tolerate oral potassium well. The side effects that show up in a small number of people are belly pain, belching, diarrhea, gas, nausea, and vomiting. Serious side effects like heart rhythm problems or low blood pressure are rare but can happen if potassium levels get too high.
Is it safe to take while pregnant or breastfeeding?
Potassium from food is fine in both cases. If you want to use this supplement during pregnancy or while breastfeeding, check with your doctor or pharmacist first — they can advise you based on your individual health.
Can I take this with my blood-pressure medicine?
It depends on which medicine you take. If you're on an ACE inhibitor, ARB, or potassium-sparing diuretic, this product isn't safe without your doctor's or pharmacist's approval — the combination can raise your potassium to dangerous levels. Check your exact medications with the tool on this page before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bloat Less is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bloat Less label
Go deeper

The Full Monographs Behind Bloat Less’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph →
Sources

Sources & How We Checked

Bloat Less's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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