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Dietary supplement

Blueberry Extract 10:1 Extract 5000 mg Ingredients & Drug Interactions

by Zazzee Naturals

Capsule Category: Botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Blueberry Extract 10:1 Extract 5000 mg is a dietary supplement by Zazzee Naturals with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, heart health, brain and memory health.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Blueberry Whole Fruit Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Blueberry Extract 10:1 Extract 5000 mg by Zazzee Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: blueberry whole fruit extract at a 10:1 concentration, meaning 5,000 mg per capsule of the extract itself. The remaining ingredients are inactive — pullulan, rice powder, and a capsule material (Compact Cel) — which help make the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Blueberry's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: antioxidant support with broad spectrum flavonoids.
  • We looked for evidence on: Aging, Cardiovascular disease (CVD), Diabetes, Hyperlipidemia, Hypertriglyceridemia, Metabolic syndrome — and 4 related terms.
  • The closest evidence on file: Blueberry is rated "Insufficient Reliable Evidence To Rate" for Cardiovascular disease (CVD) (Natural Medicines).
  • Also on file: Blueberry is rated "Insufficient Reliable Evidence To Rate" for Diabetes, Hyperlipidemia, Hypertriglyceridemia, Obesity, and more.

Blueberry extract shows possibly ineffective evidence for high blood pressure (hypertension). For age-related cognitive decline, anxiety, athletic performance, high cholesterol (hyperlipidemia), and heart disease prevention, the evidence we hold is insufficient to rate whether it works.

That doesn't mean it doesn't; it means the research isn't clear enough yet to make a claim.

The evidence, ingredient by ingredient Blueberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blueberries as a food are generally well tolerated. This concentrated extract has been studied less thoroughly than whole fruit.

Gastrointestinal side effects — constipation, diarrhea, nausea, and vomiting — occurred with freeze-dried blueberries in trials; in one study, about a quarter of participants taking 50 grams daily stopped due to stomach complaints in the first week. Safety data for high-dose extracts in pregnancy and breastfeeding is limited, so talk with your doctor or pharmacist before using this if you're pregnant or nursing.

Side effects, ingredient by ingredient Blueberry

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blueberry.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with us before taking this if you're on antidiabetes medications (blood sugar drugs), flurbiprofen, or buspirone. All three have documented Minor interactions with blueberry extract.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

This is a single-ingredient blueberry extract that's generally well tolerated as a food, though the concentrated supplement form hasn't been as thoroughly studied. If you take antidiabetes drugs, flurbiprofen, or buspirone, check your medications first — there's a Minor interaction risk.

Pregnant and nursing customers should ask their pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Blueberry Extract 10:1 Extract 5000 mg, straight from the product label.

Brand Zazzee Naturals
Barcode (UPC) X001VK9JNX
Net contents 120 Veggie Cap(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 318729
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Blueberry Extract 10:1 Extract 5000 mg by Zazzee Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
120
UPC/BARCODE
X001VK9JNX
IngredientAmount% DV
Blueberry Whole Fruit Extract500 mg--

Other ingredients: Pullulan, Rice, Powder, Compact Cel

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Take 1 capsule daily, preferably with food, or as directed by a healthcare practitioner.

Formula

Zazzee Naturals Blueberry Organic Extract is an all-natural herbal supplement that has been formulated to deliver a broad spectrum of flavonoids, polyphenols and anthocyanins with scientifically demonstrated antioxidant support properties. Our Organic Blueberry Extract is derived from a potent, pharmaceutical quality 10:1 extract equivalent to 5000 mg of whole fruit powder.

Extra Strength Blueberry 10:1 Extract 5000 mg Strength

Precautions

Warnings: For adults only.

Consult physician if pregnant or nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Allergen Information: Not manufactured with wheat, corn, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Storage

Store in a cool, dry place after opening.

Formulation

Natural color variation may occur in this product.

CCOF Certified Organic Certified Organic by CCOF USDA Organic Certified Organic, Non-GMO

Certified Organic, Non-GMO

Supports balanced immune response Powerful, potent antioxidant support

Allergen Information: Not manufactured with wheat, corn, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.

Made with Non-GMO ingredients

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

CCOF Certified Organic USDA Organic

Good Manufacturing Practice GMP Consistent Quality Made in USA

FDA Statement of Identity

Dietary Supplement

See for yourself

Blueberry Extract 10:1 Extract 5000 mg by Zazzee Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Blueberry Extract 10:1 Extract 5000 mg by Zazzee Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Blueberry Whole Fruit Extract

Interacts with
88 drugs
500 mg per serving Form: Vaccinium corymbosum

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most p...

Blueberry Whole Fruit Extract monograph & interactions

Other (inactive) ingredients: Pullulan, Rice, Powder, Compact Cel. These complete the product’s ingredient list but are not active constituents.

Interaction report

Blueberry Extract 10:1 Extract 5000 mg by Zazzee Naturals Drug Interactions

Want to check YOUR meds against Blueberry Extract 10:1 Extract 5000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
88Drugs
88 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Blueberry Extract 10:1 Extract 5000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Blueberry Whole Fruit Extract3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
The maker

Brand information

Manufacturer and brand details for Blueberry Extract 10:1 Extract 5000 mg, from the product label.

Zazzee Naturals

See all Zazzee Naturals products
Name
Zazzee Naturals
Street Address
400 Rella Blvd Ste 123 Box 182
City
Montebello
State
NY
Web Address
ZazzeeNaturals.com
Pharmacist Counseling Corner

Blueberry Extract 10:1 Extract 5000 mg by Zazzee Naturals: Common Questions

Does Blueberry Extract 10:1 Extract 5000 mg by Zazzee Naturals interact with any medications?
Yes. Based on its ingredients, Blueberry Extract 10:1 Extract 5000 mg has a known interaction with 88 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Blueberry Extract 10:1 Extract 5000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this give me stomach problems?
Blueberry extract is generally well tolerated, but some people experience constipation, diarrhea, nausea, or vomiting. In one trial, about 26% of people taking freeze-dried blueberries at 50 grams daily stopped because of stomach issues in the first week. Start with a lower dose to see how you respond.
Is it safe to take while pregnant or breastfeeding?
Eating blueberries as food is fine, but safety data for high-dose concentrated extracts during pregnancy and breastfeeding is limited. Talk with your doctor or pharmacist for personalized advice before starting this supplement if you're pregnant or nursing.
Does blueberry extract work for memory or brain health?
For age-related cognitive decline, the evidence we have is insufficient to say whether it works. There isn't enough reliable research yet to make a claim either way.
Will this help lower my blood pressure?
Blueberry extract shows possibly ineffective evidence for high blood pressure, so it's not likely to be a reliable choice for that purpose.
What's the 10:1 extract mean?
A 10:1 extract means 10 pounds of blueberry fruit were concentrated down into 1 pound of extract. So you're getting a more concentrated dose of the fruit's compounds in each capsule.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Blueberry Extract 10:1 Extract 5000 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Blueberry Extract 10:1 Extract 5000 mg label
Go deeper

The Full Monographs Behind Blueberry Extract 10:1 Extract 5000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Blueberry Extract 10:1 Extract 5000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blueberry 7 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

See these in context on the Blueberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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