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Dietary supplement

Blueberry Extract 5000 mg Ingredients & Drug Interactions

by Zazzee Naturals

Capsule Category: Botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Blueberry Extract 5000 mg is a dietary supplement by Zazzee Naturals with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, heart health, brain and memory health.Based on those ingredients, 88 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Blueberry Concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Blueberry Extract 5000 mg by Zazzee Naturals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 1 of its 4 active ingredients.
  • “Blueberry Concentrate” is listed as a grouped ingredient — the label gives one combined amount (5,000 mg) without saying how much of each component you get.
  • “Phenolics” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.

This product contains 4 active ingredients: Blueberry Whole Fruit Extract is the primary working ingredient — it's concentrated blueberry in extract form. The other three named actives are Anthocyanins, Polyphenols, and Flavonoids, which are naturally occurring plant compounds found in blueberries that contribute to the fruit's color and potential health properties.

The inactive ingredients — cellulose, rice powder, and silica — are the capsule material and flow agents that hold everything together.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This Blueberry product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see Blueberry's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“antioxidant support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence on blueberry extract is mixed. For high blood pressure (hypertension), it's rated possibly ineffective based on available data.

For age-related cognitive decline, anxiety, athletic performance, high cholesterol (hyperlipidemia), and cardiovascular disease, the evidence we hold is insufficient — we don't have enough reliable research to say whether it works or doesn't for these uses.

The evidence, ingredient by ingredient Blueberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Blueberries as food are eaten widely and are generally well tolerated. The extract form is also generally well tolerated, though freeze-dried blueberries at high doses can cause constipation, diarrhea, nausea, or vomiting — in one trial, about a quarter of people taking 50 grams daily reported enough stomach upset to drop out in the first week.

For pregnancy and breastfeeding, concentrated supplements haven't been well studied. While eating whole blueberries is fine, the safety of high-dose extracts during these periods isn't known.

Talk it over with your doctor or pharmacist before taking this product if you're pregnant or nursing.

Side effects, ingredient by ingredient Blueberry

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Blueberry.
  • The most serious interaction on file is rated Minor.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 88 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your doctor or pharmacist if you use antidiabetes drugs (minor risk of low blood sugar), flurbiprofen (Ansaid), or buspirone (BuSpar) — all three may have their blood levels or effects altered by the blueberry extract.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure marketed for general wellness rather than one specific gradeable purpose. Only minor medication interactions are documented, and safety information is well characterized.

Blueberry extract may be worth considering if you're looking for a supplement with a long food history and general tolerability. However, if you take antidiabetes drugs, flurbiprofen, or buspirone, check with your doctor or pharmacist first — the extract may affect how these medications work.

Same goes if you're pregnant, nursing, or prone to stomach upset.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Blueberry Extract 5000 mg, straight from the product label.

Brand Zazzee Naturals
Barcode (UPC) X001VK9JNX
Net contents 120 Veggie Cap(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 276072
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Blueberry Extract 5000 mg by Zazzee Naturals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
120
UPC/BARCODE
X001VK9JNX
IngredientAmount% DV
Anthocyanins0 NP--
Polyphenols0 NP--
Flavonoids0 NP--
Blueberry Concentrate5000 mg--
Blueberry Whole Fruit Extract500 mg--
Phenolics0 NP--

Other ingredients: Cellulose, Rice, Powder, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Take 1 capsule daily, preferably with food, or as directed by a healthcare practitioner.

Formula

Zazzee Naturals Blueberry Extract is an all-natural herbal supplement that has been formulated to deliver a broad spectrum of flavonoids with scientifically demonstrated antioxidant support properties. Our blueberry extract is derived from a potent, pharmaceutical quality 10:1 extract equivalent to 5000 mg (5g) of whole fruit powder.

Precautions

Warnings: For adults only.

Consult physician if pregnant or nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Do not eat freshness packet. Keep in bottle.

Allergen Information: Not manufactured with wheat, gluten, soy, milk, egg, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Storage

Store in a cool, dry place after opening.

General Statements

Please recycle.

FDA Statement of Identity

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Dietary Supplement

Formulation

Supports balance immune response Powerful, potent antioxidant support Pharmaceutical quality, 10X potency Blueberry Extract 5000mg strength

Allergen Information: Not manufactured with wheat, gluten, soy, milk, egg, shellfish or tree nut ingredients.

Natural color variation may occur in this product.

Made with non-GMO ingredients

Seals/Symbols

Good Manufacturing Practice GMP Consistent Quality Made in USA

See for yourself

Blueberry Extract 5000 mg by Zazzee Naturals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Blueberry Extract 5000 mg by Zazzee Naturals

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Blueberry Concentrate

Interacts with
88 drugs
5000 mg per serving

Blueberries are a nutritious fruit rich in antioxidants called anthocyanins, and eating them as part of a balanced diet is healthy and safe for most p...

Blueberry Concentrate monograph & interactions

Other (inactive) ingredients: Cellulose, Rice, Powder, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Blueberry Extract 5000 mg by Zazzee Naturals Drug Interactions

Want to check YOUR meds against Blueberry Extract 5000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
88Drugs
88 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Blueberry Extract 5000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Blueberry Concentrate3 drug types · 88 drugs

Antidiabetes Drugs

Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal and in vitro research suggests that blueberry and/or blueberry leaf extracts can lower blood glucose levels.

Likelihood Unlikely Evidence D
Buspirone (Buspar)

Theoretically, blueberry juice might increase blood levels of buspirone.
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone.

Likelihood Unlikely Evidence B
Flurbiprofen (Ansaid, Others)

Theoretically, blueberry juice might increase blood levels of flurbiprofen.
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen.

Likelihood Unlikely Evidence B
The maker

Brand information

Manufacturer and brand details for Blueberry Extract 5000 mg, from the product label.

Zazzee Naturals

See all Zazzee Naturals products
Name
Zazzee Naturals
Street Address
400 Rella Boulevard Suite 123 Dept. 182
City
Montebello
State
NY
ZipCode
10901
Pharmacist Counseling Corner

Blueberry Extract 5000 mg by Zazzee Naturals: Common Questions

Does Blueberry Extract 5000 mg by Zazzee Naturals interact with any medications?
Yes. Based on its ingredients, Blueberry Extract 5000 mg has a known interaction with 88 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Blueberry Extract 5000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my blood sugar or high cholesterol?
For cholesterol, we don't have enough reliable evidence to say whether blueberry extract works. For blood sugar, that's actually where you need to be careful — if you already take antidiabetes drugs, the extract might lower your blood sugar too much. Talk to your doctor before adding it.
Can I take this while pregnant or breastfeeding?
Eating whole blueberries is fine during both. But concentrated extracts at high doses haven't been well studied in pregnancy or while nursing. There isn't enough data to know if it's safe. Check with your doctor or pharmacist before taking it during these times.
What causes the stomach upset some people report?
Freeze-dried blueberries in high doses can trigger constipation, diarrhea, nausea, or vomiting. In one study, people taking 50 grams a day had the most trouble. Start with a lower dose if you're concerned, and stay hydrated.
Is this actually blueberry, or is it filled with other stuff?
The active ingredients are blueberry whole fruit extract plus anthocyanins, polyphenols, and flavonoids — all naturally in blueberries. The capsule itself contains cellulose, rice powder, and silica as inactive ingredients that help hold it together.
Can it help with brain health or age-related memory?
We don't have enough reliable evidence to say whether blueberry extract works for age-related cognitive decline or memory. The evidence just isn't established in the data we hold.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Blueberry Extract 5000 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Blueberry Extract 5000 mg label
Go deeper

The Full Monographs Behind Blueberry Extract 5000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Blueberry Extract 5000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Blueberry 7 references
  1. Cignarella A, Nastasi M, Cavalli E, Puglisi L. Novel lipid-lowering properties of Vaccinium myrtillus L. leaves, a traditional antidiabetic treatment, in several models of rat dyslipidaemia: a comparison with ciprofibrate. Thromb Res 1996;84:311-22. PubMed
  2. Wang SY, Lin HS. Antioxidant activity in fruits and leaves of blackberry, raspberry, and strawberry varies with cultivar and developmental stage. J Agric Food Chem 2000;48:140-6.. PubMed
  3. Martineau, L. C., Couture, A., Spoor, D., Benhaddou-Andaloussi, A., Harris, C., Meddah, B., Leduc, C., Burt, A., Vuong, T., Mai, Le P., Prentki, M., Bennett, S. A., Arnason, J. T., and Haddad, P. S. Anti-diabetic properties of the Canadian lowbush bluebe
  4. Vuong, T., Martineau, L. C., Ramassamy, C., Matar, C., and Haddad, P. S. Fermented Canadian lowbush blueberry juice stimulates glucose uptake and AMP-activated protein kinase in insulin-sensitive cultured muscle cells and adipocytes. Can J Physiol Pharma
  5. Hanley MJ, Masse G, Harmatz JS, Cancalon PF, Dolnikowski GG, Court MH, Greenblatt DJ. Effect of blueberry juice on clearance of buspirone and flurbiprofen in human volunteers. Br J Clin Pharmacol. 2013 Apr;75(4):1041-52. PubMed
  6. Basu A, Du M, Leyva MJ, et al. Blueberries decrease cardiovascular risk factors in obese men and women with metabolic syndrome. J Nutr 2010;140(9):1582-7. PubMed
  7. Basu A, Feng D, Planinic P, Ebersole JL, Lyons TJ, Alexander JM. Dietary blueberry and soluble fiber supplementation reduces risk of gestational diabetes in women with obesity in a randomized controlled trial. J Nutr 2021;151(5):1128-38. PubMed

See these in context on the Blueberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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