Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Brewer's Yeast Ingredients & Drug Interactions

by Indiana Botanic Gardens

Brewer's Yeast label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Brewer's Yeast against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Brewer's Yeast is a dietary supplement by Indiana Botanic Gardens with 1 active ingredient. Its ingredients are commonly taken for source of b vitamins, diarrhea (certain types), cold and flu support.Based on those ingredients, 136 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Brewer's Yeast. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Brewer's Yeast by Indiana Botanic Gardens

Ask about any prescription or over-the-counter medication and we check it for interactions with Brewer's Yeast by Indiana Botanic Gardens — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Brewer's Yeast by Indiana Botanic Gardens

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: brewer's yeast, a byproduct of beer brewing that's rich in B vitamins, minerals, and protein. The capsule also holds inactive ingredients — gelatin, rice flour, vegetable magnesium stearate, and silicon dioxide — which are fillers and binders that help form and stabilize the capsule.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Brewer's Yeast's overall clinical evidence instead.

Moderate

Some clinical evidence supports Brewer's Yeast for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Irritable bowel syndrome (IBS) — rated "Possibly Effective" (Natural Medicines).

The evidence for brewer's yeast is mixed. It's possibly effective for irritable bowel syndrome (IBS), but for other uses — Clostridioides difficile infection, influenza, high cholesterol, and hay fever — there isn't enough reliable evidence yet to say whether it works.

If you're considering it for a specific condition, talk with your doctor or pharmacist about what the current research shows.

The evidence, ingredient by ingredient Brewer's Yeast

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Brewer's yeast is generally well tolerated in food amounts, though it can cause gas in some people. The most common side effects are flatulence and migraine-like headaches.

Rarely, people have reported abdominal pain, anal irritation, or even more serious reactions like allergic reactions or fungemia (yeast in the bloodstream), especially in those with weakened immune systems. The safety of concentrated brewer's yeast supplements in pregnancy and breastfeeding hasn't been well studied, so ask your doctor or pharmacist for personalized advice before using it during these times.

Side effects, ingredient by ingredient Brewer's Yeast

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Brewer's Yeast.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 136 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check with your doctor or pharmacist if you use MAOIs (a Major interaction risk), antidiabetes drugs or lithium (Moderate risks), or antifungal medications (Minor risk). These are the medication types most likely to be affected.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.

Brewer's yeast may help with irritable bowel syndrome, but the evidence for other conditions is still unclear. If you take MAOIs, diabetes medications, lithium, or antifungals, check with your doctor or pharmacist before starting — the interactions can be serious.

People with weakened immune systems should be especially cautious. Talk it over with your own healthcare provider before you begin.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Brewer's Yeast, straight from the product label.

Brand Indiana Botanic Gardens
Barcode (UPC) 703308820973
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2013
DSLD ID 18399
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Brewer's Yeast by Indiana Botanic Gardens, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
15
UPC/BARCODE
703308820973
IngredientAmount% DV
Brewer's Yeast1000 mg--

Other ingredients: Gelatin, Rice Flour, Vegetable Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Take two (2) capsules once daily, with a meal, as a dietary supplement, or as directed by a physician.

Precautions

Warning: If you are taking any medications or are pregnant or nursing do not use prior to consulting a physician.

For your protection, this container has an outer safety seal. (Do not accept if missing or broken.)

KEEP OUT OF REACH OF CHILDREN

General Statements

Best if used by date on bottle.

Storage

Store in a dry, cool place.

Formula

Contains: trace amounts of wheat.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

IBG INDIANA BOTANIC GARDENS(R)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Brewer's Yeast by Indiana Botanic Gardens label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Brewer's Yeast label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Brewer's Yeast by Indiana Botanic Gardens

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container15 Amounts shown are per serving.

Brewer's Yeast

Interacts with
136 drugs
1000 mg per serving

Brewer's yeast is a nutrient-rich fungus that provides B vitamins, protein, and minerals, and a related yeast product (S. boulardii) is used for some...

Brewer's Yeast monograph & interactions

Other (inactive) ingredients: Gelatin, Rice Flour, Vegetable Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Brewer's Yeast by Indiana Botanic Gardens Drug Interactions

Want to check YOUR meds against Brewer's Yeast?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
136Drugs
9 Major 87 Moderate 40 Minor

Ingredients driving the most interactions

Brewer's Yeast 136

Individual Drug Interactions

The ingredients in Brewer's Yeast interact with 136 drugs. Click any drug to see the details.

1 of the 1 ingredient in Brewer's Yeast interact with drugs. Each result below shows which ingredient is responsible. Brewer's Yeast

Each ingredient & the kinds of drugs it affects

For each ingredient in Brewer's Yeast with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Brewer's Yeast4 drug types · 136 drugs

Monoamine Oxidase Inhibitors (Maois)

Theoretically, taking brewer's yeast with MAOIs might increase the risk of hypertension.
Brewer's yeast contains tyramine. Taking brewer's yeast with MAOIs might increase the risk for hypertensive crisis.

Likelihood Likely Evidence D
Antidiabetes Drugs

Taking brewer's yeast with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that taking chromium-containing brewer's yeast can decrease levels of blood glucose in diabetic patients being treated with antidiabetes drugs.

Likelihood Possible Evidence B
Lithium

Theoretically, taking brewer's yeast with lithium might cause additive effects and side effects.
Some brewer's yeast products contains lithium.

Likelihood Possible Evidence D
Antifungals

Theoretically, taking antifungals with some brewer's yeast products might decrease the effectiveness of brewer's yeast.
Some brewer's yeast products contain live yeast. Therefore, simultaneously taking antifungals might kill a significant number of the organisms.

Likelihood Possible Evidence D
Brewer's Yeast full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Brewer's Yeast, from the product label.

Indiana Botanic Gardens

See all Indiana Botanic Gardens products
Name
Indiana Botanic Gardens, Inc.
Street Address
3401 W. 37th Ave.
City
Hobart
State
IN
ZipCode
46342
Pharmacist Counseling Corner

Brewer's Yeast by Indiana Botanic Gardens: Common Questions

Does Brewer's Yeast by Indiana Botanic Gardens interact with any medications?
Yes. Based on its ingredients, Brewer's Yeast has a known interaction with 136 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Brewer's Yeast contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take brewer's yeast if I'm pregnant or breastfeeding?
The safety of brewer's yeast supplements at concentrated doses during pregnancy and breastfeeding hasn't been well studied. Food amounts are likely fine, but talk with your doctor or pharmacist before taking a supplement to get personalized advice for your situation.
What's the most common side effect?
Gas and bloating (flatulence) are the most common side effects people report. Migraine-like headaches also happen in some people. These effects are usually mild, especially if you're starting with a smaller dose.
Does brewer's yeast really work for IBS?
The evidence suggests it's possibly effective for irritable bowel syndrome, so it may help some people. For other conditions like high cholesterol or hay fever, there isn't enough reliable evidence yet to say.
Is brewer's yeast safe for people with weakened immune systems?
There's a concern that brewer's yeast may not be safe for people with weakened immune systems or certain health conditions. If that applies to you, talk with your doctor or pharmacist before starting.
What exactly is brewer's yeast?
Brewer's yeast is a byproduct left over from beer brewing. It's full of B vitamins, minerals, and protein, which is why it's used as a supplement.
Can brewer's yeast cause an allergic reaction?
Anaphylaxis (a serious allergic reaction) is rare, but it's been reported in sensitive individuals. Stop taking it immediately and seek emergency care if you have trouble breathing, swelling, or severe itching.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Brewer's Yeast is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Brewer's Yeast label
Go deeper

The Full Monographs Behind Brewer's Yeast’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Brewer's Yeast

Interacts with 136 drugs

Brewer's yeast is a nutrient-rich fungus that provides B vitamins, protein, and minerals, and a related yeast product (S. boulardii) is used for some types of diarrhea. Most other health cla...

Read the full Brewer's Yeast monograph →
Sources

Sources & How We Checked

Brewer's Yeast's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Brewer's Yeast 6 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Lewis SJ, Freedman AR. Review article: the use of biotherapeutic agents in the prevention and treatment of gastrointestinal disease. Aliment Pharmacol Ther 1998;12:807-22. PubMed
  3. Bahijiri, S. M., Mira, S. A., Mufti, A. M., and Ajabnoor, M. A. The effects of inorganic chromium and brewer's yeast supplementation on glucose tolerance, serum lipids and drug dosage in individuals with type 2 diabetes. Saudi.Med.J. 2000;21(9):831-837. DOI
  4. Schrauzer, G. N. and de, Vroey E. Effects of nutritional lithium supplementation on mood. A placebo-controlled study with former drug users. Biol.Trace Elem.Res. 1994;40(1):89-101. PubMed
  5. Gayathri R, Aruna T, Malar S, Shilpa B, Dhanasekar KR. Efficacy of Saccharomyces cerevisiae CNCM I-3856 as an add-on therapy for irritable bowel syndrome. Int J Colorectal Dis. 2020;35(1):139-145. PubMed
  6. Mourey F, Decherf A, Jeanne JF, et al. Saccharomyces cerevisiae I-3856 in irritable bowel syndrome with predominant constipation. World J Gastroenterol 2022;28(22):2509-2522.

See these in context on the Brewer's Yeast monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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