Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Broccoli Sprout Ingredients & Drug Interactions

by Health Ranger Select

Broccoli Sprout label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Broccoli Sprout against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Broccoli Sprout is a dietary supplement by Health Ranger Select with 4 active ingredients. Its ingredients are commonly taken for general nutrition and antioxidant support, heart and digestive health, detoxification support.Based on those ingredients, 723 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Sulforaphane, Broccoli, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Broccoli Sprout by Health Ranger Select

Ask about any prescription or over-the-counter medication and we check it for interactions with Broccoli Sprout by Health Ranger Select — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Broccoli Sprout by Health Ranger Select

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains four ingredients: broccoli powder, glucosinolates, sulforaphane, and glucoraphanin. Broccoli powder is the whole-food concentrate; the other three are phytonutrients naturally present in broccoli sprouts.

The capsule itself is made with hydroxypropylmethylcellulose, an inert filler.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Prostate cancer — rated "Possibly Effective" (Sulforaphane) (Natural Medicines).
  • On file: Colorectal cancer — rated "Possibly Effective" (Broccoli) (Natural Medicines).

Broccoli powder is possibly effective for colorectal cancer prevention based on available evidence. For bladder, breast, and gastric cancers, as well as fibromyalgia, the evidence isn't established enough for us to rate it.

Sulforaphane is possibly effective for prostate cancer but appears ineffective for Helicobacter pylori infection; evidence for its use in allergic rhinitis, asthma, and other cancers is currently insufficient.

The evidence, ingredient by ingredient Broccoli Sulforaphane

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Broccoli as a food is safe for most people, but concentrated supplements like this one are less well studied long-term. The product may cause loose stools, diarrhea, abdominal pain, or cramping, particularly at higher doses.

Sulforaphane can cause bowel discomfort, heartburn, stomach upset, vomiting, and headache; insomnia and irritability have been reported in trials. Rare cases of seizure have been reported in males with autism taking sulforaphane.

Both ingredients are rated likely safe in pregnancy and lactation based on available data, though concentrated supplement safety in these situations is not fully established — talk with your doctor or pharmacist if you're pregnant or nursing.

Side effects, ingredient by ingredient Broccoli Sulforaphane

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Sulforaphane, Broccoli.
  • The most serious interaction on file is rated Moderate.
  • For scale: 724 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check these medication types with your pharmacist before starting: CYP2A6 substrates (the most significant concern), CYP1A2 substrates, CYP3A4 substrates, and CYP2E1 substrates. These are enzyme-system categories rather than single drugs, which is why the total affected count is high.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

If you take any prescription or over-the-counter medications metabolized by your liver — especially blood thinners, certain pain relievers, antidepressants, or birth control — check with your pharmacist first. The concentrated sulforaphane and broccoli compounds in this product can speed up or slow down how your body processes drugs.

It may help with colorectal cancer prevention, but evidence for other conditions is limited.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Broccoli Sprout, straight from the product label.

Brand Health Ranger Select
Barcode (UPC) 050742582203
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD May 23, 2024
DSLD ID 313043
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Broccoli Sprout by Health Ranger Select, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
050742582203
IngredientAmount% DV
Broccoli, Powder560 mg--
Glucosinolates22568 mcg--
Sulforaphane10156 mcg--
Glucoraphanin22568 mcg--

Other ingredients: Hydroxypropylmethylcellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Glyphosate Tested Non GMO NFC Certified Laboratory Verified China Free

Formulation

Glyphosate Tested Non GMO NFC Certified

Lab tested and approved by the Health Ranger

Broccoli Sprout (280mg each) Made with Organic Broccoli Sprout Powder

Certified Organic by Natural Food Certifiers, Inc.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

If pregnant or under a doctor's care, consult your physician before using this product.

Do not use if the safety seal is broken.

Keep out of reach of children.

Manufactured in a facility which may contain nuts (peanuts, tree nuts).

Formula

Broccoli Sprout (280mg each) Made with Organic Broccoli Sprout Powder Health Ranger Select Organic Broccoli Sprout Capsules condenses the powder of nutrient-rich broccoli sprouts to bring you high levels of sulforaphane, glucosinolates, and glucorphanin - natural compounds essential to fighting off aging, reducing oxidative stress, and fueling your body with the best nutrition possible. Sprouts contain far more condensed nutrients than broccoli, so organic broccoli sprout capsules are the perfect choice.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Just take 2 convenient capsules a day and enjoy!

General Statements

(USA & Canada) 307-222-0422

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Broccoli Sprout by Health Ranger Select label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Broccoli Sprout label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Broccoli Sprout by Health Ranger Select

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Broccoli, Powder

Interacts with
187 drugs
560 mg per serving

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for...

Broccoli, Powder monograph & interactions

Glucosinolates

22568 mcg per serving

Sulforaphane

Interacts with
722 drugs
10156 mcg per serving

Sulforaphane is a natural compound found in broccoli and other cruciferous vegetables that has shown promising antioxidant and anti-inflammatory effec...

Sulforaphane monograph & interactions

Glucoraphanin

22568 mcg per serving

Other (inactive) ingredients: Hydroxypropylmethylcellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Broccoli Sprout by Health Ranger Select Drug Interactions

Want to check YOUR meds against Broccoli Sprout?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
723Drugs
723 Moderate

Ingredients driving the most interactions

Sulforaphane 722
Broccoli, Powder 187

Individual Drug Interactions

The ingredients in Broccoli Sprout interact with 723 drugs. Click any drug to see the details.

2 of the 4 ingredients in Broccoli Sprout interact with drugs. Each result below shows which ingredient is responsible. Sulforaphane Broccoli, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Broccoli Sprout with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Sulforaphane3 drug types · 722 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, sulforaphane might alter the levels and clinical effects of CYP1A2 substrates.
Animal and in vitro research shows that sulforaphane inhibits CYP1A2 enzyme activity. However, its precursor glucoraphanin also appears to increase the expression of the CYP1A2 enzyme, which could lead to increased metabolism of CYP1A2 substrates. These effects have not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2E1 (Cyp2E1) Substrates

Theoretically, sulforaphane might increase the levels and effects of CYP2E1 substrates.
In vitro evidence shows that sulforaphane inhibits CYP2E1 enzymes. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, sulforaphane might increase the levels and effects of CYP3A4 substrates.
Animal and in vitro research shows that sulforaphane inhibits CYP3A4 enzyme activity and downregulates its expression. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Sulforaphane full monograph & interactions

Broccoli, Powder2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Broccoli, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Broccoli Sprout, from the product label.

Health Ranger Select

See all Health Ranger Select products
Name
Health Ranger Store
Street Address
3800 N. Lamar Blvd, Suite 200
City
Austin
State
TX
ZipCode
78756
Phone Number
1-888-959-6415
Web Address
HealthRangerStore.com
Pharmacist Counseling Corner

Broccoli Sprout by Health Ranger Select: Common Questions

Does Broccoli Sprout by Health Ranger Select interact with any medications?
Yes. Based on its ingredients, Broccoli Sprout has a known interaction with 723 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Broccoli Sprout contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this upset my stomach?
Possible — broccoli sprout extracts have caused loose stools, diarrhea, abdominal pain, and cramping, especially at higher doses. Sulforaphane can cause heartburn, stomach upset, bowel discomfort, and in some cases nausea or vomiting. Start with a lower dose to see how you tolerate it.
Is it safe if I'm pregnant or breastfeeding?
The broccoli powder and sulforaphane are rated likely safe during pregnancy and lactation based on available data. That said, concentrated supplements haven't been as thoroughly studied as whole broccoli food in these situations — talk with your doctor or pharmacist about what's right for your individual needs.
Does this actually prevent cancer?
Broccoli powder is possibly effective for colorectal cancer based on current evidence. For other cancers (breast, bladder, gastric), and for other health claims, the evidence isn't strong enough yet for us to say either way.
What's sulforaphane and why is it in here?
Sulforaphane is a compound naturally found in broccoli sprouts. It's been studied for prostate cancer prevention, though it appears ineffective against Helicobacter pylori bacteria. It's in the product because broccoli sprouts are a rich source of it.
Can I take this with my other supplements?
You'll want to check with your pharmacist — this isn't just about medications, but about how broccoli compounds can speed up or slow down how your body metabolizes other substances. The interaction potential is real even with supplements.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Broccoli Sprout is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Broccoli Sprout label
Go deeper

The Full Monographs Behind Broccoli Sprout’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Broccoli

Interacts with 187 drugs

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...

Read the full Broccoli monograph → Herb & supplement monograph

Sulforaphane

Interacts with 722 drugs

Sulforaphane is a natural compound found in broccoli and other cruciferous vegetables that has shown promising antioxidant and anti-inflammatory effects in lab studies, but strong human evid...

Read the full Sulforaphane monograph →
Sources

Sources & How We Checked

Broccoli Sprout's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Sulforaphane 16 references
  1. Park EJ, Pezzuto JM. Botanicals in cancer chemoprevention. Cancer Metastasis Rev 2002;21:231-55. PubMed
  2. Barcelo S, Mace K, Pfeifer AM, Chipman JK. Production of DNA strand breaks by N-nitrosodimethylamine and 2-amino-3-methylimidazo[4,5-f]quinoline in THLE cells expressing human CYP isoenzymes and inhibition by sulforaphane. Mutat Res 1998;402:111-20. PubMed
  3. Cipolla BG, Mandron E, Lefort JM, et al. Effect of sulforaphane in men with biochemical recurrence after radical prostatectomy. Cancer Prev Res (Phila). 2015;8(8):712-9. PubMed
  4. Fahey JW, Wade KL, Wehage SL, et al. Stabilized sulforaphane for clinical use: Phytochemical delivery efficiency. Mol Nutr Food Res. 2017 Apr;61(4). PubMed
  5. Alumkal JJ, Slottke R, Schwartzman J, et al. A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer. Invest New Drugs. 2015;33(2):480-9. PubMed
  6. Heber D, Li Z, Garcia-Lloret M, et al. Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles. Food Funct. 2014;5(1):35-41. PubMed
  7. Singh K, Connors SL, Macklin EA, et al. Sulforaphane treatment of autism spectrum disorder (ASD). Proc Natl Acad Sci U S A. 2014;111(43):15550-5. PubMed
  8. Wise RA, Holbrook JT, Criner G, et al. Lack of effect of oral sulforaphane administration on Nrf2 expression in COPD: A randomized, double-blind, placebo controlled trial. PLoS One. 2016;11(11):e0163716. PubMed
  9. Bent S, Lawton B, Warren T, et al. Identification of urinary metabolites that correlate with clinical improvements in children with autism treated with sulforaphane from broccoli. Mol Autism. 2018;9:35. PubMed
  10. Momtazmanesh S, Amirimoghaddam-Yazdi Z, Moghaddam HS, Mohammadi MR, Akhondzadeh S. Sulforaphane as an adjunctive treatment for irritability in children with autism spectrum disorder: A randomized, double-blind, placebo-controlled clinical trial. Psychiatr PubMed
  11. Fimognari C, Lenzi M, Hrelia P. Interaction of the isothiocyanate sulforaphane with drug disposition and metabolism: pharmacological and toxicological implications. Curr Drug Metab. 2008;9(7):668-78. PubMed
  12. Chinnappan SM, George A, Evans M, Anthony J. Efficacy of Labisia pumila and Eurycoma longifolia standardised extracts on hot flushes, quality of life, hormone and lipid profile of peri-menopausal and menopausal women: a randomised, placebo-controlled stud
  13. Mahéo K, Morel F, Langouët S, et al. Inhibition of cytochromes P-450 and induction of glutathione S-transferases by sulforaphane in primary human and rat hepatocytes. Cancer Res. 1997;57(17):3649-52.
  14. Yoxall V, Kentish P, Coldham N, Kuhnert N, Sauer MJ, Ioannides C. Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity. Int J Cancer. 2005;117(3):356-62. PubMed
  15. Zimmerman AW, Singh K, Connors SL, et al. Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder. Mol Autism 2021;12(1):38.
  16. Yusin J, Wang V, Henning SM, et al. The effect of broccoli sprout extract on seasonal grass pollen-induced allergic rhinitis. Nutrients 2021;13(4):1337. PubMed

See these in context on the Sulforaphane monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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