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Dietary supplement

Bupleurum Root 900 mg Ingredients & Drug Interactions

by NasaBe'Ahava

Bupleurum Root 900 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bupleurum Root 900 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bupleurum Root 900 mg is a dietary supplement by NasaBe'Ahava with 1 active ingredient. Its ingredients are commonly taken for liver and digestive support, cold, flu, and fever, inflammation.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bupleurum. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Bupleurum Root 900 mg by NasaBe'Ahava

Ask about any prescription or over-the-counter medication and we check it for interactions with Bupleurum Root 900 mg by NasaBe'Ahava — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Bupleurum Root 900 mg by NasaBe'Ahava

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: bupleurum root at 900 mg per capsule. Bupleurum is a plant root used in traditional herbal medicine, particularly in Asian formulations.

The capsule itself is made from gelatin and rice powder as inactive ingredients.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: immune system support and respiratory function.
  • We looked for evidence on: Influenza, Respiratory tract infections, common cold, fever, immune response.
  • The closest evidence on file: Bupleurum is rated "Insufficient Reliable Evidence To Rate" for Respiratory tract infections (Natural Medicines).
  • Also on file: Bupleurum is rated "Insufficient Reliable Evidence To Rate" for Influenza.

The evidence for what bupleurum actually does isn't established in the data we hold. Its effectiveness for asthma, liver cancer, respiratory infections, depression, epilepsy, and hepatitis B all show insufficient reliable evidence to rate.

This means we don't have enough solid research to say whether it works for these purposes or not.

The evidence, ingredient by ingredient Bupleurum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bupleurum is generally used short-term in herbal formulas, but it's been linked to rare lung and liver problems — including pneumonitis (lung inflammation), pulmonary edema (fluid in the lungs), and eosinophilic pneumonia — though it's unclear whether bupleurum alone or other ingredients in combination products caused these. Quality also varies between suppliers.

In one combination product called sho-saiko-to, people reported nausea, loss of appetite, abdominal fullness, fatigue, and tingling sensations, though again it's unclear which ingredient was responsible. During pregnancy and breastfeeding, there isn't enough safety information, so the data advises against use.

Talk with your doctor or pharmacist about whether this is right for your situation.

Side effects, ingredient by ingredient Bupleurum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bupleurum.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check this product against blood thinners and antiplatelet drugs first — bupleurum may increase bleeding risk (Moderate severity). Also flag immunosuppressants and diabetes medications, which bupleurum might make less effective (Moderate severity).

Use the interaction search tool on this page for your specific medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Bupleurum root is a single-herb supplement with limited research backing its effectiveness for the conditions it's traditionally used for. If you take blood thinners, immunosuppressants, or diabetes medications, you need to check this against your exact prescriptions before starting — the interaction risk is real.

A conversation with your pharmacist is the smart first step.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 21, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bupleurum Root 900 mg, straight from the product label.

Brand NasaBe'Ahava
Barcode (UPC) 795853352900
Net contents 180 Capsule(s)
Market status On market
Date entered into DSLD Dec 21, 2024
DSLD ID 322008
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bupleurum Root 900 mg by NasaBe'Ahava, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
90
UPC/BARCODE
795853352900
IngredientAmount% DV
Bupleurum900 mg--

Other ingredients: Gelatin, Rice, Powder

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, take two (2) capsules daily, preferably with a meal.

Precautions

As a reminder, discuss the supplements and medications you take with your health care providers. Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Sourced from a GMP Certified Facility Good Manufacturing Practice Quality Assured Made in USA

100% Money back guarantee

Formulation

Premium quality. Solid support Immune system support Helps support your immune system Enhance respiratory functions Extra strength formula

Contains no: artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.

We have assayed & fully guarantee the quality & potency of this product Manufactured at an FDA-Inspected Facility.

FDA Statement of Identity

Dietary Supplement

Storage

Store in a dry place and avoid excessive heat.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bupleurum Root 900 mg by NasaBe'Ahava label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bupleurum Root 900 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bupleurum Root 900 mg by NasaBe'Ahava

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Bupleurum

Interacts with
327 drugs
900 mg per serving Form: Bupleurum chinense

Bupleurum (Chai Hu) is a root used in traditional Chinese medicine, usually as part of multi-herb formulas, for liver, digestive, and fever-related co...

Bupleurum monograph & interactions

Other (inactive) ingredients: Gelatin, Rice, Powder. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bupleurum Root 900 mg by NasaBe'Ahava Drug Interactions

Want to check YOUR meds against Bupleurum Root 900 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Bupleurum 327

Individual Drug Interactions

The ingredients in Bupleurum Root 900 mg interact with 327 drugs. Click any drug to see the details.

1 of the 1 ingredient in Bupleurum Root 900 mg interact with drugs. Each result below shows which ingredient is responsible. Bupleurum

Each ingredient & the kinds of drugs it affects

For each ingredient in Bupleurum Root 900 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bupleurum3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, bupleurum might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research suggests that saikosaponins, constituents of bupleurum, can inhibit platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, bupleurum might decrease the effects of antidiabetes drugs.
Animal research suggests that saikosaponins, constituents of bupleurum, can increase blood glucose.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, bupleurum might decrease the effects of immunosuppressants.
In vitro and animal research suggests that bupleurum might stimulate immune function.

Likelihood Possible Evidence D
Bupleurum full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bupleurum Root 900 mg, from the product label.

NasaBe'Ahava

See all NasaBe'Ahava products
Name
NasaBe'Ahava
Street Address
20229 NE 16th Pl
City
Miami
State
FL
ZipCode
33179
Phone Number
1-877-407-6272
Web Address
NasaVitamins.com
Pharmacist Counseling Corner

Bupleurum Root 900 mg by NasaBe'Ahava: Common Questions

Does Bupleurum Root 900 mg by NasaBe'Ahava interact with any medications?
Yes. Based on its ingredients, Bupleurum Root 900 mg has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bupleurum Root 900 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against it — there isn't enough information to know it's safe either way. Talk with your doctor or pharmacist about your personal situation before using this product.
What side effects have been reported?
In one combination product containing bupleurum (sho-saiko-to), people reported nausea, loss of appetite, stomach fullness, fatigue, and tingling. Rare but serious lung problems like pneumonia and fluid in the lungs have also been reported in combination products, though it's not always clear if bupleurum alone was responsible.
Does bupleurum actually work for any of these conditions?
The evidence isn't established yet. We don't have enough reliable research to say whether it works for asthma, liver cancer, infections, depression, epilepsy, or hepatitis B.
Why does the quality vary?
The product facts note that bupleurum quality varies between suppliers. This is common with herbal ingredients, which is why sourcing matters.
Is this safe to use long-term?
Bupleurum is generally used short-term in herbal formulas, and it's been linked to rare lung and liver problems. If you're thinking of taking it regularly, that's a conversation to have with your pharmacist or doctor.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Bupleurum Root 900 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bupleurum Root 900 mg label
Go deeper

The Full Monographs Behind Bupleurum Root 900 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bupleurum

Interacts with 327 drugs

Bupleurum (Chai Hu) is a root used in traditional Chinese medicine, usually as part of multi-herb formulas, for liver, digestive, and fever-related complaints. High-quality human evidence fo...

Read the full Bupleurum monograph →
Sources

Sources & How We Checked

Bupleurum Root 900 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bupleurum 17 references
  1. Kobashi Y, Nakajima M, Niki Y, Matsushima T. [A case of acute eosinophilic pneumonia due to Sho-saiko-to]. Nippon Kyobu Shikkan Gakkai Zasshi 1997;35:1372-7.
  2. Wada Y, Kubo M. [Acute lymphoblastic leukemia complicated by type C hepatitis during treatment and further by acute interstitial pneumonia due to sho-saiko-to in 7-year-old]. Arerugi 1997;46:1148-55.
  3. Sato A, Toyoshima M, Kondo A, et al. [Pneumonitis induced by the herbal medicine Sho-saiko-to in Japan]. Nippon Kyobu Shikkan Gakkai Zasshi 1997;35:391-5.
  4. Daibo A, Yoshida Y, Kitazawa S, et al. [A case of pneumonitis and hepatic injury caused by a herbal drug (sho-saiko-to)]. Nippon Kyobu Shikkan Gakkai Zasshi 1992;30:1583-8.
  5. Sugiyama H, Nagai M, Kotajima F, et al. [A case of interstitial pneumonia with chronic hepatitis C following interferon-alfa and sho-saiko-to therapy]. Arerugi 1995;44:711-4.
  6. Ishizaki T, Sasaki F, Ameshima S, et al. Pneumonitis during interferon and/or herbal drug therapy in patients with chronic active hepatitis. Eur Respir J 1996;9:2691-6. PubMed
  7. Nakagawa A, Yamaguchi T, Takao T, Amano H. [Five cases of drug induced pneumonitis due to Sho-saiko-to or interferon-alpha or both]. Nippon Kyobu Shikkan Gakkai Zasshi 1995;33:1361-6.
  8. Miyazaki E, Ando M, Ih K, et al. [Pulmonary edema associated with the Chinese medicine shosaikoto]. Nihon Kokyuki Gakkai Zasshi 1998;36:776-80.
  9. Matsumoto T, Yamada H. Regulation of immune complexes binding of macrophages by pectic polysaccharide from Bupleurum falcatum L.: pharmacological evidence for the requirement of intracellular calcium/calmodulin on Fc receptor up-regulation by bupleuran 2
  10. Hattori T, Ito M, Suzuki Y. [Studies on antinephritic effects of plant components in rats (1). Effects of saikosaponins original-type anti-GBM nephritis in rats and its mechanisms]. Nippon Yakurigaku Zasshi 1991;97:13-21. PubMed
  11. Chang WC, Hsu FL. Inhibition of platelet activation and endothelial cell injury by flavan-3-ol and saikosaponin compounds. Prostaglandins Leukot Essent Fatty Acids 1991;44:51-6. PubMed
  12. Kato M, Pu MY, Isobe K, et al. Characterization of the immunoregulatory action of saikosaponin-d. Cell Immunol 1994;159:15-25. PubMed
  13. Ushio Y, Oda Y, Abe H. Effect of saikosaponin on the immune responses in mice. Int J Immunopharmacol 1991;13:501-8. PubMed
  14. Hirayama, C., Okumura, M., Tanikawa, K., and et al. A multicenter randomized controlled clinical trial of Shosaiko-to in chronic active hepatitis. Gastroenterol Jpn 1989;24(6):715-719. PubMed
  15. Hiai S, Yokoyama H, Nagasawa T, and et al. Stimulation of the pituitary-adrenocortical axis by saikosaponin of Bupleuri radix. Chemical and Pharmaceutical Bulletin (Tokyo) 1981;29(2):495-499. PubMed
  16. Yokoyama H, Hiai S, and Oura H. Chemical structures and corticosterone secretion-inducing activities of saikosaponins. Chem Pharm Bull (Tokyo) 1981;29(2):500-504. PubMed
  17. Sugiyama H, Nagai M, Kotajima F, and et al. [A case of interstitial pneumonia with chronic hepatitis C following interferon-alfa and sho-saiko-to therapy]. Arerugi 1995;44(7):711-714.

See these in context on the Bupleurum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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