CanLaze Ingredients & Drug Interactions
What is this page for?
First and foremost: checking CanLaze against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
CanLaze is a dietary supplement by Wholly Liquid with 2 active ingredients. Its ingredients are commonly taken for digestive upset and poor appetite, intestinal parasites, crohn's disease symptoms.Based on those ingredients, 172 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Pau d'Arco Extract, Wormwood Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against CanLaze by Wholly Liquid
Ask about any prescription or over-the-counter medication and we check it for interactions with CanLaze by Wholly Liquid — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of CanLaze by Wholly Liquid
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
CanLaze is a 2-ingredient liquid supplement. It contains Wormwood Extract and Pau d'Arco Extract, both traditional botanicals used in herbal medicine.
The remaining ingredients—purified water, vegetable glycerin, citric acid, sorbic acid, and potassium salt—are inactive ingredients that serve as the base, preservative, and pH buffer for the liquid formulation.
Does it work?
Couldn't assess
The evidence for both active ingredients in this product is not well established. Wormwood Extract has insufficient reliable evidence for biliary disorders, Crohn disease, depression, dyspepsia, and osteoarthritis.
Pau d'Arco Extract likewise shows insufficient reliable evidence for cancer, peptic ulcers, wound healing, and dysmenorrhea. If you're considering this product for a specific health concern, talk with your pharmacist or doctor about whether stronger evidence exists for other options.
How safe is it?
Well-documented data
Wormwood Extract carries real safety concerns. It contains thujone, a neurotoxin that can cause muscle aches, nausea, and vomiting even in typical medicinal amounts; at higher doses or with chronic use, it's linked to kidney damage, muscle breakdown, seizures, and serious neurological effects including hallucinations, tremors, and brain damage.
Pau d'Arco Extract is generally well tolerated at lower doses, but its active compound lapachol can cause anemia, bleeding risk, and severe nausea or diarrhea when doses exceed 1.5 grams daily. Wormwood is unsafe during pregnancy—it may stimulate the uterus—and safety data is insufficient for breastfeeding.
Pau d'Arco should be avoided during pregnancy due to possible harm to the developing baby, and there isn't enough safety information for breastfeeding. Short-term use of properly prepared wormwood products may be acceptable, but human safety data for pau d'arco is limited.
Meds to double-check
Moderate interaction found
Before you take CanLaze, check your medications with the tool on this page if you take anticonvulsants (seizure medications)—wormwood may interfere with their effectiveness. Also check if you take blood thinners or antiplatelet drugs like warfarin or aspirin—pau d'arco may increase bleeding risk.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This is a niche herbal product with limited evidence for its intended uses and real safety trade-offs, especially around wormwood's thujone content. It's not a first-line choice for any of the conditions it may target.
If you take anticonvulsants or blood thinners, this product poses documented interaction risks and should not be used without explicit guidance from your pharmacist or doctor. Talk to us before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about CanLaze, straight from the product label.
| Brand | Wholly Liquid |
|---|---|
| Barcode (UPC) | WLCAZE30 |
| Net contents | 1 Fluid Ounce(s); 30 mL |
| Market status | On market |
| Date entered into DSLD | Sep 22, 2022 |
| DSLD ID | 272083 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), No Allergies, Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for CanLaze by Wholly Liquid, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Wormwood Extract | 200 mg | -- |
| Pau d'Arco Extract | 200 mg | -- |
Other ingredients: purified Water, Vegetable Glycerin, Citric Acid, Sorbic Acid, Potassium Salt
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: Take 5-15 drops in 1-2 oz. of water, three times per day on an empty stomach or as directed by your healthcare professional.
Storage
Storage Instructions: Store at room temperature away from direct sunlight. Keep tightly closed.
Precautions
Warning: Consult your healthcare professional before use if you are pregnant, nursing, taking medications, have a known medical condition, or for any use by minors.
Warning: Consult your healthcare professional before use if you are pregnant, nursing, taking medications, have a known medical condition, or for any use by minors.
Do not use if safety seal is broken or missing.
Keep out of reach of children.
For nutritional use only.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Made in USA
Supports the elimination of candida, molds & fungi
Soy free Dairy free Sugar free Gluten free
Vegan
Alcohol free Allergen free No artificial colors or sugars No synthetic fillers or binders
Brand IP Statement(s)
Supplements as good as food
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
CanLaze by Wholly Liquid label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in CanLaze by Wholly Liquid
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size5 Drop(s) Dosage formLiquid Servings per container30 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Wormwood Extract
Interacts with50 drugs
Wormwood is a very bitter herb traditionally used to stimulate appetite and ease digestion, and it has early research interest in Crohn's disease. It...
Wormwood Extract monograph & interactionsPau d'Arco Extract
Interacts with122 drugs
Pau d'arco is a South American tree bark traditionally used for infections and inflammation, and it contains compounds like lapachol that show activit...
Pau d'Arco Extract monograph & interactionsOther (inactive) ingredients: Purified Water, Vegetable Glycerin, Citric Acid, Sorbic Acid, Potassium Salt. These complete the product’s ingredient list but are not active constituents.
CanLaze by Wholly Liquid Drug Interactions
HelloPharmacist Interaction Report
CanLaze by Wholly Liquid contains two herbal extracts, and together they interact with a significant number of medications.
Wormwood Extract carries a Moderate interaction risk with anticonvulsants (seizure medications); thujone, one of wormwood's natural compounds, has convulsant properties and may interfere with how these drugs work. Pau d'Arco Extract poses a Moderate interaction risk with blood thinners and antiplatelet drugs (like warfarin or aspirin); research suggests pau d'arco can reduce how platelets clump together and may interfere with vitamin K, raising the risk of bleeding.
Read the full breakdown — every affected drug type, severity by severity
Altogether, these interactions span 172 individual medications. Both ingredients carry cautions around dose and duration—wormwood's thujone can be toxic at higher amounts, and pau d'arco's active compound lapachol has been linked to serious side effects (bleeding, anemia, severe nausea) when doses exceed 1.5 grams daily.
Before you start this product, check your exact medications with the search tool on this page, especially if you take seizure medications or blood thinners.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against CanLaze?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in CanLaze interact with 172 drugs. Click any drug to see the details.
2 of the 2 ingredients in CanLaze interact with drugs. Each result below shows which ingredient is responsible. Pau d'Arco Extract Wormwood Extract
AbciximabReoPro
How Abciximab interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Abrocitinib interactionAcenocoumarolSintrom
How Acenocoumarol interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Wormwood ExtractAnticonvulsants Moderate
Interaction Summary
Theoretically, taking wormwood might interfere with the effects of anticonvulsant drugs.
Read the full Wormwood Extract + Acetazolamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Acetylsalicylic Acid interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAminophylline, Amobarbital, EphedrineAmesec
How Aminophylline, Amobarbital, Ephedrine interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Wormwood ExtractAnticonvulsants Moderate
Interaction Summary
Theoretically, taking wormwood might interfere with the effects of anticonvulsant drugs.
Read the full Wormwood Extract + Aminophylline, Amobarbital, Ephedrine interactionAmobarbitalAmytal
How Amobarbital interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Wormwood ExtractAnticonvulsants Moderate
Interaction Summary
Theoretically, taking wormwood might interfere with the effects of anticonvulsant drugs.
Read the full Wormwood Extract + Amobarbital interactionAmobarbital, Ephedrine SulfateEphedrine & Amytal
How Amobarbital, Ephedrine Sulfate interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Wormwood ExtractAnticonvulsants Moderate
Interaction Summary
Theoretically, taking wormwood might interfere with the effects of anticonvulsant drugs.
Read the full Wormwood Extract + Amobarbital, Ephedrine Sulfate interactionAmobarbital, SecobarbitalTuinal
How Amobarbital, Secobarbital interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Wormwood ExtractAnticonvulsants Moderate
Interaction Summary
Theoretically, taking wormwood might interfere with the effects of anticonvulsant drugs.
Read the full Wormwood Extract + Amobarbital, Secobarbital interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Anisindione interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Apixaban interactionAprobarbital, Butabarbital, PhenobarbitalTriple Barbital
How Aprobarbital, Butabarbital, Phenobarbital interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Wormwood ExtractAnticonvulsants Moderate
Interaction Summary
Theoretically, taking wormwood might interfere with the effects of anticonvulsant drugs.
Read the full Wormwood Extract + Aprobarbital, Butabarbital, Phenobarbital interactionArgatrobanArgatroban
How Argatroban interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Argatroban interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Aspirin interactionAspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #3
How Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Aspirin, Aluminum Hydroxide, Codeine Phosphate, Magnesium Hydroxide interactionAspirin, ButalbitalAxotal
How Aspirin, Butalbital interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Aspirin, Butalbital interactionAspirin, Butalbital, CaffeineFiorinal
How Aspirin, Butalbital, Caffeine interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Aspirin, Butalbital, Caffeine interactionAspirin, Butalbital, Caffeine, Codeine PhosphateFiorinal w/ Codeine
How Aspirin, Butalbital, Caffeine, Codeine Phosphate interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Aspirin, Butalbital, Caffeine, Codeine Phosphate interactionAspirin, Butalbital, Caffeine, PhenacetinMarnal
How Aspirin, Butalbital, Caffeine, Phenacetin interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Aspirin, Butalbital, Caffeine, Phenacetin interactionAspirin, CaffeineAnacin
How Aspirin, Caffeine interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Aspirin, Caffeine interactionAspirin, Caffeine, Codeine PhosphateAnacin w/ Codeine
How Aspirin, Caffeine, Codeine Phosphate interacts with CanLaze — through 1 ingredient. Tap an ingredient for the detail:
Pau D'arco ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Pau D'arco Extract + Aspirin, Caffeine, Codeine Phosphate interactionEach ingredient & the kinds of drugs it affects
For each ingredient in CanLaze with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Pau d'Arco Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, pau d'arco might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that pau d'arco reduces platelet aggregation and may interfere with vitamin K. One clinical study shows that taking the lapachol constituent of pau d'arco in doses above 1.5 grams daily increases the risk of bleeding. The effects of whole pau d'arco or pau d'arco extract in humans are unclear.
Wormwood Extract
Anticonvulsants
Theoretically, taking wormwood might interfere with the effects of anticonvulsant drugs.
Thujone, a constituent of wormwood, has convulsant effects.
Brand information
Manufacturer and brand details for CanLaze, from the product label.
Wholly Liquid
See all Wholly Liquid products- Name
- Wholly Liquid Nutritional Supplements, LLC
- City
- Hampton
- State
- NH
- ZipCode
- 03842
- Web Address
- www.whollyliquid.com
CanLaze by Wholly Liquid: Common Questions
Does CanLaze by Wholly Liquid interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take CanLaze if I'm pregnant or breastfeeding?
What does Wormwood Extract do?
What does Pau d'Arco Extract do?
What are the side effects of CanLaze?
Is CanLaze safe to use long-term?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if CanLaze is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind CanLaze’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Wormwood
Interacts with 50 drugsWormwood is a very bitter herb traditionally used to stimulate appetite and ease digestion, and it has early research interest in Crohn's disease. It contains thujone, which can be toxic in...
Read the full Wormwood monograph → Herb & supplement monographPau D'arco
Interacts with 122 drugsPau d'arco is a South American tree bark traditionally used for infections and inflammation, and it contains compounds like lapachol that show activity in lab studies. However, strong human...
Read the full Pau D'arco monograph →Sources & How We Checked
CanLaze's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 16 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Wormwood 10 references
- Weisbord SD, Soule JB, Kimmel PL. Poison on line-acute renal failure caused by oil of wormwood purchased through the internet. N Engl J Med 1997;337:825-7. PubMed
- Gambelunghe C, Melai P. Absinthe: enjoying a new popularity among young people? Forensic Sci Int 2002;130:183-6.
- Hold KM, Sirisoma NS, Casida JE. Detoxification of alpha- and beta-Thujones (the active ingredients of absinthe): site specificity and species differences in cytochrome P450 oxidation in vitro and in vivo. Chem Res Toxicol 2001;14:589-95.
- Lachenmeier DW, Walch SG, Padosch SA, Kroner LU. Absinthe--a review. Crit Rev Food Sci Nutr 2006;46:365-77.
- Padosch SA, Lachenmeier DW, Kroner LU. Absinthism: a fictitious 19th century syndrome with present impact. Subst Abuse Treat Prev Policy 2006;1:14. PubMed
- Lachenmeier DW, Emmert J, Kuballa T, Sartor G. Thujone--cause of absinthism? Forensic Sci Int 2006;158:1-8. PubMed
- Dettling, A., Grass, H., Schuff, A., Skopp, G., Strohbeck-Kuehner, P., and Haffner, H. T. Absinthe: attention performance and mood under the influence of thujone. J Stud.Alcohol 2004;65(5):573-581. PubMed
- Benezet-Mazuecos, J. and de la Fuente, A. Electrocardiographic findings after acute absinthe intoxication. Int J Cardiol. 11-10-2006;113(2):e48-e50. PubMed
- El Makrini NI, Hassam B. Artemisia absinthium: burning plant! Pan Afr Med J. 2016 Jan 22;23:10. PubMed
- Kocaoglu C, Ozel A. Persistent metabolic acidosis and severe diarrhoea due to Artemisia absinthium poisoning. J Pak Med Assoc. 2014 Sep;64(9):1081-3.
Pau D'arco 6 references
- Gómez Castellanos JR, Prieto JM, Heinrich M. Red Lapacho (Tabebuia impetiginosa)--a global ethnopharmacological commodity? J Ethnopharmacol 2009;121:1-13. PubMed
- Guerra, Mde O., Mazoni, A. S., Brandao, M. A., and Peters, V. M. Toxicology of Lapachol in rats: embryolethality. Braz.J Biol. 2001;61(1):171-174. PubMed
- Felicio, A. C., Chang, C. V., Brandao, M. A., Peters, V. M., and Guerra, Mde O. Fetal growth in rats treated with lapachol. Contraception 2002;66(4):289-293. PubMed
- Son, D. J., Lim, Y., Park, Y. H., Chang, S. K., Yun, Y. P., Hong, J. T., Takeoka, G. R., Lee, K. G., Lee, S. E., Kim, M. R., Kim, J. H., and Park, B. S. Inhibitory effects of Tabebuia impetiginosa inner bark extract on platelet aggregation and vascular s
- Block JB, Serpick AA, Miller W, Wiernik PH. Early clinical studies with lapachol (NSC-11905). Cancer Chemother Rep 2. 1974;4(4):27-8.
- Algranti E, Mendonça EM, Ali SA, Kokron CM, Raile V. Occupational asthma caused by Ipe (Tabebuia spp) dust. J Investig Allergol Clin Immunol 2005;15(1):81-3.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC