Cape Aloe Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Cape Aloe against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cape Aloe is a dietary supplement by Douglas Laboratories with 1 active ingredient. Its ingredients are commonly taken for minor burns and skin irritation, wound healing, constipation.Based on those ingredients, 461 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Cape Aloe. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Cape Aloe by Douglas Laboratories
Ask about any prescription or over-the-counter medication and we check it for interactions with Cape Aloe by Douglas Laboratories — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Cape Aloe by Douglas Laboratories
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product is one ingredient: Cape Aloe, the latex extract of the aloe plant. The rest is just the capsule shell and inactive fillers (microcrystalline cellulose, gelatin, and vegetable stearate).
Does it work?
Moderate evidence
Aloe is rated Possibly Effective for six uses in our data: acne, obesity, diabetes, psoriasis, burns, and constipation. That means there's some preliminary clinical evidence, but it's not definitive—more research would help confirm how well it actually works for any of these conditions.
How safe is it?
Well-documented data
Topical aloe gel is generally well tolerated, but oral aloe latex—the form in this capsule—carries greater risk, especially at high doses or with long-term use. The most common side effects are abdominal pain, cramps, and diarrhea.
Long-term overuse can cause more serious effects: severe potassium loss (hypokalemia), muscle weakness, irregular heartbeats, and a harmless but visible darkening of the colon lining (pseudomelanosis coli, which reverses when you stop). Do not take this product during pregnancy—aloe latex may stimulate the uterus and act as a strong laxative.
Avoid it while breastfeeding too, because safety data is limited and the laxative effects could affect your baby.
Meds to double-check
Major interaction found
Check with your pharmacist before taking this if you use digoxin (Lanoxin), blood thinners (anticoagulants) or antiplatelet drugs, diabetes medications, diuretics, warfarin (Coumadin), stimulant laxatives, or drugs processed by the CYP1A2 enzyme. The biggest concern is digoxin—potassium depletion can raise toxicity risk.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Major medication interactions have been identified, and safety information is well characterized.
Cape Aloe might help with constipation, acne, or skin conditions, but it's not a proven cure. If you take digoxin, blood thinners, diabetes drugs, diuretics, or warfarin, talk to your pharmacist or doctor before starting—the interaction risks are real.
The same goes for any other prescription medication; check it below. And if you're pregnant or nursing, skip this product.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cape Aloe, straight from the product label.
| Brand | Douglas Laboratories |
|---|---|
| Barcode (UPC) | 310539015612 |
| Net contents | 100 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2020 |
| DSLD ID | 232287 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cape Aloe by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Cape Aloe | 250 mg | -- |
Other ingredients: Microcrystalline Cellulose, Gelatin, Vegetable Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Usage: As a dietary supplement, adults take 1 capsule daily as needed in the evening or as directed by your health professional. Not intended for long-term use.
Precautions
Warning: Not to be taken by pregnant or lactating women. If you have any health condition or are taking any medication, consult your health professional before use.
Keep out of the reach of children.
Use only if safety seal is intact.
Storage
Store in a cool, dry place.
Formulation
Gluten-free, Non-GMO
Gastrointestinal regularity
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
General Statements
Scan to learn about our manufacturing excellence Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cape Aloe by Douglas Laboratories label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cape Aloe by Douglas Laboratories
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.
Cape Aloe
Interacts with461 drugs
Aloe vera gel is widely used on the skin for minor burns and irritation, and some research suggests it may help. Aloe latex (the yellow part) is a str...
Cape Aloe monograph & interactionsOther (inactive) ingredients: Microcrystalline Cellulose, Gelatin, Vegetable Stearate. These complete the product’s ingredient list but are not active constituents.
Cape Aloe by Douglas Laboratories Drug Interactions
HelloPharmacist Interaction Report
Cape Aloe by Douglas Laboratories contains one active ingredient—aloe latex—which does interact with several medication types, and the most serious concern is digoxin (Lanoxin), a heart medication.
Overuse of aloe latex can deplete potassium, which increases the risk of toxicity and adverse effects when you're on digoxin.
Read the full breakdown — every affected drug type, severity by severity
Aloe also has Moderate-severity interactions with blood thinners (anticoagulants) and antiplatelet drugs, diabetes medications, diuretics, stimulant laxatives, and warfarin. With blood thinners or warfarin, aloe's laxative effect can trigger diarrhea, which boosts the drug's blood-thinning action and raises bleeding risk.
Diabetes drugs are at risk of additive effects, potentially dropping your blood sugar too low (hypoglycemia). Diuretics and stimulant laxatives both cause potassium loss, and aloe can compound that problem.
There's also a Minor-severity interaction with CYP1A2 substrates—a group of drugs that aloe may make less effective.
Altogether, these interactions span 461 individual medications. Run your exact medications through the checker below before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Cape Aloe?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Cape Aloe interact with 461 drugs. Click any drug to see the details.
1 of the 1 ingredient in Cape Aloe interact with drugs. Each result below shows which ingredient is responsible. Cape Aloe
AbciximabReoPro
How Abciximab interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Cape Aloe + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Cape Aloe + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Cape Aloe + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Acetaminophen, Ibuprofen interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeCytochrome P450 1a2 (cyp1a2) Substrates, Diuretic Drugs Moderate
Interaction Summary
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
Read the full Cape Aloe + Acetaminophen, Pamabrom, Pyrilamine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Cape Aloe + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Cape Aloe + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Cape Aloe + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Cape Aloe + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Cape Aloe + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Cape Aloe + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Cape Aloe + Amiloride, Hydrochlorothiazide interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeDiuretic Drugs Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Read the full Cape Aloe + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Anacaulase-bcdb interactionAnagrelideAgrylin
How Anagrelide interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Anagrelide interactionAnisindioneMiradon
How Anisindione interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Anisindione interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAntidiabetes Drugs Moderate
Interaction Summary
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Cape Aloe + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionAntithrombin IiiThrombate III
How Antithrombin Iii interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Antithrombin Iii interactionApixabanEliquis
How Apixaban interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Apixaban interactionArgatrobanArgatroban
How Argatroban interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Argatroban interactionArmodafinilNuvigil
How Armodafinil interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeStimulant Laxatives Moderate
Interaction Summary
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Read the full Cape Aloe + Armodafinil interactionAspirinAngettes 75, ASA, Asaphen, Aspirin, Caprin, Cartia +8 more
How Aspirin interacts with Cape Aloe — through 1 ingredient. Tap an ingredient for the detail:
Cape AloeAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Cape Aloe + Aspirin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Cape Aloe with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Cape Aloe
Digoxin (Lanoxin)
Theoretically, aloe latex might increase the risk of adverse effects when taken with cardiac glycosides.
Overuse of aloe latex can increase the risk of adverse effects from cardiac glycoside drugs, such as digoxin, due to potassium depletion. Overuse of aloe, along with cardiac glycoside drugs, can increase the risk of toxicity.
Anticoagulant/Antiplatelet Drugs
Theoretically, aloe gel might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aloe gel can inhibit platelet aggregation. This inhibition was greater than that seen with celecoxib, but less than that seen with aspirin.
Antidiabetes Drugs
Aloe might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Preliminary clinical research suggests aloe gel might lower blood glucose levels and have additive effects when used with antidiabetes drugs. Monitor blood glucose levels closely.
Diuretic Drugs
Theoretically, aloe latex might increase the risk of hypokalemia when taken with diuretic drugs.
Overuse of aloe latex might compound diuretic-induced potassium loss, increasing the risk of hypokalemia.
Stimulant Laxatives
Theoretically, aloe latex might increase the risk for fluid and electrolyte loss when taken with stimulant laxatives.
Due to cathartic laxative effects of aloe latex, concomitant use with other stimulant laxatives might compound fluid and electrolyte loss.
Warfarin (Coumadin)
Theoretically, aloe latex might increase the risk of bleeding when taken with warfarin.
Aloe latex has stimulant laxative effects. In some people aloe latex can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of aloe vera.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, aloe might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that aloe extract induces CYP1A2 enzymes.
Brand information
Manufacturer and brand details for Cape Aloe, from the product label.
Douglas Laboratories
See all Douglas Laboratories products- Name
- Douglas Laboratories
- Street Address
- 600 Boyce Road
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15205
- Phone Number
- 1.800.245.4440
- Web Address
- www.douglaslabs.com
Cape Aloe by Douglas Laboratories: Common Questions
Does Cape Aloe by Douglas Laboratories interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What's the difference between aloe gel and aloe latex?
Can I take this long-term?
Will this help my constipation?
Is it safe during pregnancy?
What if I'm on a water pill (diuretic) for my blood pressure?
Does aloe cause that dark pigment I've heard about?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cape Aloe is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cape Aloe’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Cape Aloe's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 41 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Aloe 41 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
- Luyckx VA, Ballantine R, Claeys M, et al. Herbal remedy-associated acute renal failure secondary to Cape aloes. Am J Kidney Dis 2002;39:E13. PubMed
- Rajasekaran S, Sivagnanam K, Ravi K, Subramanian S. Hypoglycemic effect of Aloe vera gel on streptozotocin-induced diabetes in experimental rats. J Med Food 2004;7:61-6.
- Williams MS, Burk M, Loprinzi CL, et al. Phase III double-blind evaluation of an aloe vera gel as a prophylactic agent for radiation-induced skin toxicity. Int J Radiat Oncol Biol Phys 1996;36:345-9. PubMed
- Vogler BK, Ernst E. Aloe vera: a systematic review of its clinical effectiveness. Br J Gen Pract 1999;49:823-8.
- Bottenberg MM, Wall GC, Harvey RL, Habib S. Oral aloe vera-induced hepatitis. Ann Pharmacother 2007;41:1740-3. PubMed
- Rabe C, Musch A, Schirmacher P, et al. Acute hepatitis induced by an Aloe vera preparation: a case report. World J Gastroenterol 2005;11:303-4. PubMed
- Kanat O, Ozet A, Ataergin S. Aloe vera-induced acute toxic hepatitis in a healthy young man. Eur J Int Med 2006;17:589. PubMed
- Mueller SO, Stopper H. Characterization of the genotoxicity of anthraquinones in mammalian cells. Biochim Biophys Acta 1999;1428:406-14. PubMed
- Schorkhuber M, Richter M, Dutter A, et al. Effect of anthraquinone laxatives on the proliferation and urokinase secretion of normal, premalignant and malignant colonic epithelial cells. Eur J Cancer 1998;34:1091-8. PubMed
- Yang HN, Kim DJ, Kim YM, et al. Aloe-induced toxic hepatitis. J Korean Med Sci 2010;25:492-5. PubMed
- Choonhakarn C, Busaracome P, Sripanidkulchai B, et al. A prospective, randomized clinical trial comparing topical aloe vera with 0.1% triamcinolone acetonide in mild to moderate plaque psoriasis. J.Eur.Acad.Dermatol.Venereol. 2010;24:168-72. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. IV. Mechanism of cathartic effect. (3). Biol Pharm Bull. 1994;17:495-7. PubMed
- Ishii Y, Tanizawa H, Takino Y. Studies of aloe. V. Mechanism of cathartic effect. (4). Biol Pharm Bull. 1994;17:651-3. PubMed
- Nelemans FA. Clinical and toxicological aspects of anthraquinone laxatives. Pharmacology. 1976;14 Suppl 1:73-7. PubMed
- Paulsen E, Korsholm L, Brandrup F. A double-blind, placebo-controlled study of a commercial Aloe vera gel in the treatment of slight to moderate psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2005;19:326-31.
- Huseini HF, Kianbakht S, Hajiaghaee R, et al. Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Planta Med. 2012;78:311-6
- Ferreira, M., Teixeira, M., Silva, E., and Selores, M. Allergic contact dermatitis to Aloe vera. Contact Dermatitis 2007;57(4):278-279.
- Choonhakarn, C., Busaracome, P., Sripanidkulchai, B., and Sarakarn, P. The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial. Br J Dermatol 2008;158(3):573-577. PubMed
- Baretta, Z., Ghiotto, C., Marino, D., and Jirillo, A. Aloe-induced hypokalemia in a patient with breast cancer during chemotherapy. Ann.Oncol. 2009;20(8):1445-1446. PubMed
- Hunter, D. and Frumkin, A. Adverse reactions to vitamin E and aloe vera preparations after dermabrasion and chemical peel. Cutis 1991;47(3):193-196.
- Alvarez-Perea, A., Garcia, A. P., Hernandez, A. L., de, Barrio M., and Baeza, M. L. Urticaria due to aloe vera: a new sensitizer? Ann.Allergy Asthma Immunol. 2010;105(5):404-405. PubMed
- Hogan, D. J. Widespread dermatitis after topical treatment of chronic leg ulcers and stasis dermatitis. CMAJ. 2-15-1988;138(4):336-338.
- Savchak VI. Acute bullous allergic dermatitis due to local application of aloe leaves. Vestnik Dermatologii i Venerologii 1977;12:44-45.
- Nakamura, T. and Kotajima, S. Contact dermatitis from aloe arborescens. Contact Dermatitis 1984;11(1):51. PubMed
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