Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Carb Blocker Ingredients & Drug Interactions

by Applied Nutrition

Tablet Or Pill Category: Botanical With Nutrients
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Carb Blocker is a dietary supplement by Applied Nutrition with 2 active ingredients. Its ingredients are commonly taken for blood sugar support in type 2 diabetes, weight loss and appetite control, insulin sensitivity.Based on those ingredients, 178 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chromium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Carb Blocker by Applied Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Applied Nutrition's Carb Blocker has two active ingredients: chromium and white kidney bean extract. Chromium is a mineral that plays a role in how your body handles blood sugar and may support insulin function.

White kidney bean extract is derived from the legume and is often used in carb-blocking supplements, though we hold limited interaction data for it. The tablet also contains inactive ingredients — fillers and binders like calcium phosphate, stearic acid, and magnesium stearate that help hold the tablet together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: neutralize carbohydrate enzymes decrease digested calories.
  • We looked for evidence on: Obesity, Metabolic syndrome, Impaired glucose tolerance (Prediabetes), Diabetes, Weight management, Carbohydrate metabolism — and 2 related terms.
  • The strongest evidence on file: Chromium is rated "Possibly Effective" for Diabetes (Natural Medicines).
  • Also on file: Chromium is rated "Possibly Ineffective" for Impaired glucose tolerance (Prediabetes).
  • Also on file: Chromium is rated "Insufficient Reliable Evidence To Rate" for Obesity, Metabolic syndrome.

The evidence for chromium is mixed. It's likely effective for treating a true chromium deficiency, which is rare.

For type 2 diabetes, the evidence suggests it may possibly help — some research shows it can lower blood glucose, especially in people whose diabetes isn't well controlled. For prediabetes (impaired glucose tolerance), high blood pressure, and schizophrenia, the evidence is too weak or negative to support its use.

The facts we hold don't include specific effectiveness data for the white kidney bean extract in this product.

The evidence, ingredient by ingredient Chromium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chromium is generally well tolerated at typical supplement doses. The most common side effects are stomach irritation, headaches, insomnia, irritability, and mood changes.

Skin rashes, itching, and hives have been reported, especially in people with a chromium contact allergy. Rare but serious effects — kidney or liver damage, muscle breakdown, and low platelet counts — have been documented, mostly with high or long-term doses.

For pregnancy, small amounts from food or prenatal vitamins are generally considered acceptable, but extra chromium supplements should be avoided unless your doctor recommends it. The safety data for higher supplement doses is limited.

For breastfeeding, limited data suggest it's likely safe, but talk with your doctor for personalized advice.

Side effects, ingredient by ingredient Chromium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chromium.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 178 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your pharmacist if you take insulin or any antidiabetes medications — chromium may lower your blood sugar further and increase hypoglycemia risk. Also flag levothyroxine (thyroid medication) and any NSAIDs or aspirin you use regularly.

These interactions are moderate to minor, but your pharmacist needs to know.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Carb Blocker may be worth considering if you're interested in chromium's blood-sugar effects, but it's not a decision to make alone — especially if you take insulin, antidiabetes drugs, or levothyroxine. Those medications need your pharmacist's go-ahead.

Check your exact pills against the interaction tool on this page before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 1, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Carb Blocker, straight from the product label.

Brand Applied Nutrition
Net contents 28 Tablet(s)
Market status On market
Date entered into DSLD Oct 1, 2012
DSLD ID 13305
Product type Botanical With Nutrients
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Carb Blocker by Applied Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
1 Tablet(s)
Servings per container
28
IngredientAmount% DV
Chromium100 mcg83%
Common Bean (White Kidney Bean) extract1000 mg--

Other ingredients: Dibasic Calcium Phosphate Dihydrate, Stearic Acid, Croscarmellose Sodium, Silicon Dioxide, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

PRODUCT 2: CARB-BLOCKER Scientifically-designed to neutralize carbohydrate enzymes and decrease the number of carb calories digested by the body.

CARB-BLOCKER BOTTLE 2: Neutralize Carbohydrate Calories

PRODUCT 2: CARB-BLOCKER

A reduced calorie diet & exercise plan, plus tips on continued weight support, visit: www.AppliedNutrition.com/deplan

The Bootcamp Mission: To help you achieve a healthier body weight in two weeks, so you look and feel great!

How It Works: This intensive diet system supplies four powerful products that, when used in combination with a reduced calorie diet and exercise plan, can help to maximize your weight loss efforts.

4-in-ONE DOCTOR-DEVELOPED HARDCORE DIET!

This program requires that you follow a reduced calorie diet & exercise plan.

Take the 2-Week Challenge! Are you looking to lose some weight, but frustrated with your results? Are you trying to get back into those skinny jeans or to fit into that new dress for a big event? Or would you like to feel more confident while wearing less?

“Stick with it for two weeks… and you will find that the results are worth the effort!”

Suggested/Recommended/Usage/Directions

Product 2: Carb-Blocker: (Adult) Take one (1) tablet twice daily before starchy meals & snacks.

Notice: For best results we recommend limiting the consumption of additional caffeine while using this product (e.g. less than three 8 ounce cups of coffee per day).

Precautions

Not intended for use by persons under 18 years of age.

KEEP OUT OF REACH OF CHILDREN.

Do not use if you are pregnant or nursing.

Usage Warnings: Do not use if safety seal is broken. Do not exceed recommended daily intake.

This product contains caffeine and may affect blood pressure and/or heart conditions. If you are under the care of a physician, please consult your physician before using this product.

Consult your physician before using this product if you are taking heart medications, diuretics or have a medical condition.

Do not use if you have an intestinal obstruction, hemorrhoids or other intestinal/digestive disorder.

KEEP OUT OF REACH OF CHILDREN.

Not intended for use by persons under 18 years of age.

WARNING: (State of California Prop 65) This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.

Storage

Store in a cool, dry place.

Brand IP Statement(s)

Applied Nutrition(R) is committed to developing science-based products that exceed the highest standards for quality and purity. As a leader in innovation, we continuously strive to bring forward new ideas and groundbreaking formulas that enhance health and well-being. To view our entire line of products, please visit us online at: www.AppliedNutrition.com

2-Week Bootcamp Extreme Diet(TM) is a doctor-developed system that is specially designed to give you the hardcore results that you are looking for. This intense multi-product & diet program is unlike anything you have tried before.

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Carb Blocker by Applied Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Carb Blocker by Applied Nutrition

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container28 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Chromium

Interacts with
178 drugs
100 mcg per serving Form: Chromium Picolinate

Chromium is an essential trace mineral involved in how the body handles sugar and fat. Some studies suggest it may modestly help blood sugar control i...

Chromium monograph & interactions

Common Bean (White Kidney Bean) extract

1000 mg per serving

Other (inactive) ingredients: Dibasic Calcium Phosphate Dihydrate, Stearic Acid, Croscarmellose Sodium, Silicon Dioxide, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Carb Blocker by Applied Nutrition Drug Interactions

Want to check YOUR meds against Carb Blocker?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
178Drugs
89 Moderate 89 Minor

Ingredients driving the most interactions

Chromium 178

Each ingredient & the kinds of drugs it affects

For each ingredient in Carb Blocker with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Chromium5 drug types · 178 drugs

Antidiabetes Drugs

Theoretically, chromium may have additive effects with antidiabetic agents and increase the risk of hypoglycemia.
Some research shows that taking chromium might lower blood glucose levels, especially in patients with poorly controlled type 2 diabetes.

Likelihood Possible Evidence A
Insulin

Theoretically, concomitant use of chromium and insulin might increase the risk of hypoglycemia.
In clinical research, chromium has been shown to increase insulin sensitivity,

Likelihood Possible Evidence B
Levothyroxine (Synthroid, Others)

Chromium might bind levothyroxine in the intestinal tract and decrease levothyroxine absorption.
Clinical research in healthy volunteers shows that taking chromium picolinate 1000 mcg with levothyroxine 1 mg decreases serum levels of levothyroxine by 17% when compared to taking levothyroxine alone. Advise patients to take levothyroxine at least 30 minutes before or 3-4 hours after taking chromium.

Likelihood Probable Evidence B
Aspirin

Theoretically, aspirin might increase chromium absorption.
Animal research suggests that aspirin may increase chromium absorption and chromium levels in the blood.

Likelihood Possible Evidence D
Nonsteroidal Anti-Inflammatory Drugs (Nsaids)

NSAIDs might increase chromium levels in the body.
Drugs that are prostaglandin inhibitors, such as NSAIDs, seem to increase chromium absorption and retention.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Carb Blocker, from the product label.

Applied Nutrition

See all Applied Nutrition products
Name
Applied Nutrition(R)
Street Address
P.O. Box 66457
City
Los Angeles
State
CA
ZipCode
90066
Pharmacist Counseling Corner

Carb Blocker by Applied Nutrition: Common Questions

Does Carb Blocker by Applied Nutrition interact with any medications?
Yes. Based on its ingredients, Carb Blocker has a known interaction with 178 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Carb Blocker contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this help you lose weight or block carbs?
The product contains chromium and white kidney bean extract, both marketed for carb-blocking support. We have evidence that chromium may possibly help with type 2 diabetes blood-sugar control, but evidence for weight loss or blocking carbs isn't in the data we hold. Results vary widely, and this isn't a substitute for diet and exercise.
Can I take this if I'm pregnant?
Small amounts of chromium from food or prenatal vitamins are generally considered acceptable during pregnancy. But extra supplement doses should be avoided unless your doctor recommends it. Talk with your doctor or pharmacist before adding this product — they can give you personalized advice based on your situation.
What are the most common side effects?
Stomach upset, headaches, insomnia, irritability, and mood changes are the most common. Skin rashes and itching have also been reported, especially in people allergic to chromium. Serious side effects are rare but can include kidney or liver damage at high or long-term doses.
Is chromium safe long-term?
Chromium is usually well tolerated at typical supplement doses, but we don't have enough safety data on higher or long-term doses. It's safest to take it only as directed and let your doctor know if you're using it regularly.
Will this affect my thyroid medication?
Yes — chromium may reduce how much levothyroxine (Synthroid and other thyroid drugs) your body absorbs. Research shows it can lower blood levels by around 17%. Your pharmacist may suggest taking them several hours apart, but you need to check with them first before starting this product.
What's white kidney bean extract for?
White kidney bean extract is used in carb-blocking supplements. We don't have detailed interaction or effectiveness data for this ingredient in our system, so ask your pharmacist if you have questions about what it does.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Carb Blocker is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Carb Blocker label
Sources

Sources & How We Checked

Carb Blocker's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 53 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chromium 53 references
  1. Cerulli J, Grabe DW, Gauthier I, et al. Chromium picolinate toxicity. Ann Pharmacother 1998;32:428-31. PubMed
  2. Urberg M, Zemel MB. Evidence for synergism between chromium and nicotinic acid in the control of glucose tolerance in elderly humans. Metabolism 1987;36:896-9. PubMed
  3. Mohamedshah FY, Moser-Veillon PB, Yamini S, et al. Distribution of a stable isotope of chromium (53Cr) in serum, urine, and breast milk in lactating women. Am J Clin Nutr 1998;67:1250-5. PubMed
  4. Wasser WG, Feldman NS, D'Agati VD. Chronic renal failure after ingestion of over-the-counter chromium picolinate. [letter]. Ann Intern Med 1997;126:410. PubMed
  5. Mertz W. Interaction of chromium with insulin: a progress report. Nutr Rev 1998;56:174-7. PubMed
  6. Anderson RA. Chromium, glucose intolerance and diabetes. J Am Coll Nutr 1998;17:548-55. PubMed
  7. McLeod MN, Gaynes BN, Golden RN. Chromium potentiation of antidepressant pharmacotherapy for dysthymic disorder in 5 patients. J Clin Psych 1999;60:237-40. PubMed
  8. Fowler JF Jr. Systemic contact dermatitis caused by oral chromium picolinate. Cutis 2000;65:116. DOI
  9. Trent LK, Thieding-Cancel D. Effects of chromium picolinate on body composition. J Sports Med Phys Fitness 1995;35:273-80.
  10. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  11. Rabinovitz H, Friedensohn A, Leibovitz A, et al. Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients. Int J Vitam Nutr Res 2004;74:178-82. PubMed
  12. Lanca S, Alves A, Vieira AI, et al. Chromium-induced toxic hepatitis. Eur J Intern Med 2002;13:518-20. PubMed
  13. Kockler DR, McCarthy MW, Lawson CL. Seizure activity and unresponsiveness after hydroxycut ingestion. Pharmacotherapy 2001;21:647-51.. PubMed
  14. Davidson JR, Abraham K, Connor KM, McLeod MN. Effectiveness of chromium in atypical depression: a placebo-controlled trial. Biol Psychiatry 2003;53:261-4.. PubMed
  15. Food Standards Agency. Medicines and Healthcare products Regulatory Agency (MHRA). Expert Group on Vitamins and Minerals. Available at: http://cot.food.gov.uk/sites/default/files/vitmin2003.pdf.
  16. Mouser JF, Hak EB, Helms RA, et al. Chromium and zinc concentrations in pediatric patients receiving long-term parenteral nutrition. Am J Health Syst Pharm 1999;56:1950-6. PubMed
  17. Stevens T, Qadri A, Zein NN. Two patients with acute liver injury associated with use of the herbal weight-loss supplement hydroxycut. Ann Intern Med 2005;142:477-8. PubMed
  18. Wani S, Weskamp C, Marple J, Spry L. Acute tubular necrosis associated with chromium picolinate-containing dietary supplement. Ann Pharmacother 2006;40:563-6. PubMed
  19. Kleefstra N, Houweling ST, Jansman FG, et al. Chromium treatment has no effect in patients with poorly controlled, insulin-treated type 2 diabetes in an obese Western population: a randomized, double-blind, placebo-controlled trial. Diabetes Care 2006;29: PubMed
  20. Martin J, Wang ZQ, Zhang XH, et al. Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes. Diabetes Care 2006;29:1826-32. PubMed
  21. Singer GM, Geohas J. The effect of chromium picolinate and biotin supplementation on glycemic control in poorly controlled patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized trial. Diabetes Technol Ther 2006;8:636-43. PubMed
  22. John-Kalarickal J, Pearlman G, Carlson HE. New medications which decrease levothyroxine absorption. Thyroid 2007;17:763-5. PubMed
  23. Yazaki Y, Faridi Z, Ma Y, et al. A pilot study of chromium picolinate for weight loss. J Altern Complement Med 2010;16:291-9. PubMed
  24. Davis ML, Seaborn CD, and Stoecker BJ. Effects of over-the-counter drugs on chromium retention and urinary excretion in rats. Nutrition Research 1995;15(2):201-210.
  25. Young P, Turiansky G, Bonner M, and et al. Acute generalized exanthematous pustulosis induced by chromium picolinate. J.Am Acad.Dermatol. 1999;41(5 Pt 2):820-823. PubMed
  26. Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Lung cancer among workers in chromium chemical production. Am J Ind.Med 2000;38(2):115-126. DOI
  27. Gibb, H. J., Lees, P. S., Pinsky, P. F., and Rooney, B. C. Clinical findings of irritation among chromium chemical production workers. Am J Ind.Med 2000;38(2):127-131. PubMed
  28. Pittler, M. H. and Ernst, E. Dietary supplements for body-weight reduction: a systematic review. Am.J.Clin Nutr. 2004;79(4):529-536. PubMed
  29. Pei, D., Hsieh, C. H., Hung, Y. J., Li, J. C., Lee, C. H., and Kuo, S. W. The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial. Metabolism 2 PubMed
  30. Hisatomi, K., Ishii, H., Hashiguchi, K., Seki, M., Ide, M., Sugiyama, K., Ishimoto, H., Nakayama, S., Mukae, H., and Kohno, S. Interstitial pneumonia caused by inhalation of fumes of nickel and chrome. Respirology. 2006;11(6):814-817. PubMed
  31. Kleefstra, N., Houweling, S. T., Bakker, S. J., Verhoeven, S., Gans, R. O., Meyboom-de Jong, B., and Bilo, H. J. Chromium treatment has no effect in patients with type 2 diabetes in a Western population: a randomized, double-blind, placebo-controlled tri DOI
  32. Parsons, A., Ingram, J., Inglis, J., Aveyard, P., Johnstone, E., Brown, K., Franklin, M., and Bermudez, I. A proof of concept randomised placebo controlled factorial trial to examine the efficacy of St John's wort for smoking cessation and chromium to pr
  33. Bagdon RE and Hazen RE. Skin permeation and cutaneous hypersensitivity as a basis for making risk assessments of chromium as a soil contaminant. Environ.Health Perspect. 1991;92:111-119. PubMed
  34. Bharmal, S. V., Moyes, V., Ahmed, S., and Grossman, A. Hypoglycaemia: possible mediation by chromium salt medication. Hormones.(Athens.) 2010;9(2):181-183. PubMed
  35. Krol, E., Krejpcio, Z., Byks, H., Bogdanski, P., and Pupek-Musialik, D. Effects of chromium brewer's yeast supplementation on body mass, blood carbohydrates, and lipids and minerals in type 2 diabetic patients. Biol.Trace Elem.Res. 2011;143(2):726-737.
  36. Unisa, S., Jagannath, P., Dhir, V., Khandelwal, C., Sarangi, L., and Roy, T. K. Population-based study to estimate prevalence and determine risk factors of gallbladder diseases in the rural Gangetic basin of North India. HPB (Oxford) 2011;13(2):117-125. PubMed
  37. Noda, S., Asano, Y., and Sato, S. Lichen planus in a patient with long-term exposure to chrome. Eur.J.Dermatol. 2011;21(3):417-418. PubMed
  38. Xiang, J., Sun, Z., and Huan, J. N. Intensive chromic acid burns and acute chromium poisoning with acute renal failure. Chin Med.J.(Engl.) 7-5-2011;124(13):2071-2073.
  39. Chhabra, D., Oda, K., Jagannath, P., Utsunomiya, H., Takekoshi, S., and Nimura, Y. Chronic heavy metal exposure and gallbladder cancer risk in India, a comparative study with Japan. Asian Pac.J.Cancer Prev. 2012;13(1):187-190. PubMed
  40. Huszonek, J. Over-the-counter chromium picolinate. Am J Psychiatry 1993;150(10):1560-1561. PubMed
  41. Bunner S and McGinnis R. Chromium-induced hypoglycemia. Psychosomatics 1998;39(3):298-299. PubMed
  42. Martin, W. R. and Fuller, R. E. Suspected chromium picolinate-induced rhabdomyolysis. Pharmacotherapy 1998;18(4):860-862. DOI
  43. Proctor, D. M., Fredrick, M. M., Scott, P. K., Paustenbach, D. J., and Finley, B. L. The prevalence of chromium allergy in the United States and its implications for setting soil cleanup: a cost-effectiveness case study. Regul.Toxicol Pharmacol 1998;28(1 PubMed
  44. De Marchi S, Cecchin E, De Marchi SU. Systemic allergic dermatitis resulting from oral administration of chromium with a food supplement. Contact Dermatitis 2014;70(2):123-5. PubMed
  45. Hedberg YS, Gumulka M, Lind ML, Matura M, Lidén C. Severe occupational chromium allergy despite cement legislation. Contact Dermatitis. 2014;70(5):321-3. PubMed
  46. Thyssen JP, Jellesen MS, Møller P, Menné T, Johansen JD. Allergic chromium dermatitis from wearing 'chromium-free' footwear. Contact Dermatitis 2014;70(3):185-7. PubMed
  47. Liu Y, Cotillard A, Vatier C, et al. A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized, Placebo-Controlled Trial. PLoS One.
  48. Jamilian M, Asemi Z. Chromium Supplementation and the Effects on Metabolic Status in Women with Polycystic Ovary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. Ann Nutr Metab. 2015;67(1):42-8. PubMed
  49. Guimarães MM, Carvalho AC, Silva MS. Effect of chromium supplementation on the glucose homeostasis and anthropometry of type 2 diabetic patients: Double blind, randomized clinical trial: Chromium, glucose homeostasis and anthropometry. J Trace Elem Med Bi PubMed
  50. Paiva AN, Lima JG, Medeiros AC, et al. Beneficial effects of oral chromium picolinate supplementation on glycemic control in patients with type 2 diabetes: A randomized clinical study. J Trace Elem Med Biol. 2015;32:66-72. PubMed
  51. Yin RV, Phung OJ. Effect of chromium supplementation on glycated hemoglobin and fasting plasma glucose in patients with diabetes mellitus. Nutr J. 2015;14:14. PubMed
  52. Jamilian M, Zadeh Modarres S, Amiri Siavashani M, et al. The influences of chromium supplementation on glycemic control, markers of cardio-metabolic risk, and oxidative stress in infertile polycystic ovary syndrome women candidate for in vitro fertilizati
  53. Alinaghi F, Thyssen JP, Zachariae C, Johansen JD. No immediate effect of regulatory reduction of chromium in leather among adult patients with chromium allergy. Contact Dermatitis 2021;85(5):514-522. PubMed

See these in context on the Chromium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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