Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Chewable Probiotic Natural Grape Flavor Ingredients & Drug Interactions

by American Health

Chewable Probiotic Natural Grape Flavor label
See full label image
Tablet Or Pill Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chewable Probiotic Natural Grape Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Chewable Probiotic Natural Grape Flavor is a dietary supplement by American Health with 2 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus DDS-1. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Chewable Probiotic Natural Grape Flavor by American Health

Ask about any prescription or over-the-counter medication and we check it for interactions with Chewable Probiotic Natural Grape Flavor by American Health — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Chewable Probiotic Natural Grape Flavor by American Health

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Oct 1, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Probiotic Blend” is a proprietary blend — the label gives one combined amount (16 mg) without saying how much of each component you get.

This chewable tablet contains two active ingredients: a proprietary probiotic blend and Lactobacillus acidophilus DDS-1, a strain of beneficial bacteria. These probiotics are meant to support your gut health by restoring balance to your intestinal bacteria.

The tablet also contains several inactive ingredients — xylitol, tricalcium phosphate, fructooligosaccharide, natural flavors, vegetable juice color, malic acid, silica, magnesium stearate, guar gum, and stevia leaf extract — that make up the tablet structure and flavor.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Lactobacillus Acidophilus's overall clinical evidence instead.

Moderate

Some clinical evidence supports Lactobacillus Acidophilus for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Antibiotic-associated diarrhea — rated "Possibly Effective" (Natural Medicines).
  • On file: Bacterial vaginosis — rated "Possibly Effective" (Natural Medicines).
  • On file: Helicobacter pylori — rated "Possibly Effective" (Natural Medicines).
  • On file: Irritable bowel syndrome (IBS) — rated "Possibly Effective" (Natural Medicines).

Lactobacillus acidophilus is rated possibly effective for irritable bowel syndrome (IBS), Helicobacter pylori infection, antibiotic-associated diarrhea, and bacterial vaginosis, meaning some evidence supports its use but more study is needed. It's rated possibly ineffective for atopic disease (allergic conditions), and the evidence isn't established for acute respiratory distress syndrome (ARDS).

The data we hold doesn't show effectiveness ratings for Bifidobacterium animalis lactis UABla-12.

The evidence, ingredient by ingredient Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy adults and children. Because it contains live, active organisms, there's a theoretical concern it could cause serious infections in some patients — cases of bacteremia, sepsis, and other infections have been reported, though most are thought to occur when bacteria move from other parts of the body where they occur naturally.

Some people taking probiotics report mild gastrointestinal side effects like stomach discomfort, bloating, gas, diarrhea, or nausea, but these are uncommon. A small number of trial participants taking a probiotic combination developed a rash or itching, though it's unclear whether L. acidophilus or another factor was responsible.

During pregnancy, Lactobacillus acidophilus is rated possibly safe; lactation safety data aren't on file for this ingredient. Talk with your doctor or pharmacist before starting, especially if you're pregnant, breastfeeding, or have a weakened immune system.

Side effects, ingredient by ingredient Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you're on antibiotic drugs — taking this probiotic at the same time may reduce how well the probiotic works. You may need to space them out differently.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic may be worth considering if you have IBS, antibiotic-related diarrhea, or certain other digestive concerns — the evidence is modest but present. If you take antibiotics, timing matters: separate when you take them from this probiotic to keep it effective.

Check your exact medications with your doctor or pharmacist before you start, and let them know if you have a weakened immune system or other health concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chewable Probiotic Natural Grape Flavor, straight from the product label.

Brand American Health
Net contents 60 Chewable Tablet(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 317679
Product type Non-nutrient/non-botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chewable Probiotic Natural Grape Flavor by American Health, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Chewable Tablet(s)
Maximum serving Sizes:
1 Chewable Tablet(s)
Servings per container
60
IngredientAmount% DV
Proprietary Probiotic Blend16 mg--
Lactobacillus acidophilus DDS-10 NP--
Bifidobacterium animalis lactis UABla-120 NP--

Other ingredients: Xylitol, Tricalcium Phosphate, Fructooligosaccharide, Natural Flavors, Vegetable juice color, Malic Acid, Silica, Magnesium Stearate, Guar Gum, Stevia Leaf Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

No gluten, no wheat, no dairy, no lactose, no sugar, no soy, no egg, no peanuts, no tree nuts, no fish. Non-GMO.

Vegetarian

Colony Forming Units (CFUs) Guaranteed through printed expiration date.

Non-GMO Dairy-Free

Formula

Made with Natural Flavors and Colors

5 Billion Live Cultures Friendly Bacteria for Digestive & Immune Systems

Natural Grape Flavor with other Natural Flavors

Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur. Do not use if seal under cap is broken or missing.

Keep out of reach of children.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Storage

Guaranteed quality and CFU through expiration when continuously stored in the original packaging as directed. Store in a cool, dry place away from direct sunlight.

No refrigeration required.

Brand IP Statement(s)

DDS-1 and UABla-12 are trademarks of Chr. Hansen A/S and used under license.

Copyright 2021 American Health, Inc.

FDA Statement of Identity

Probiotic Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, chew one (1) tablet daily. Do not swallow whole.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chewable Probiotic Natural Grape Flavor by American Health label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chewable Probiotic Natural Grape Flavor label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chewable Probiotic Natural Grape Flavor by American Health

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Chewable Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Probiotic Blend

16 mg per serving

Other (inactive) ingredients: Xylitol, Tricalcium Phosphate, Fructooligosaccharide, Natural Flavors, Vegetable juice color, Malic Acid, Silica, Magnesium Stearate, Guar Gum, Stevia Leaf Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chewable Probiotic Natural Grape Flavor by American Health Drug Interactions

Want to check YOUR meds against Chewable Probiotic Natural Grape Flavor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus acidophilus DDS-1 182

Individual Drug Interactions

The ingredients in Chewable Probiotic Natural Grape Flavor interact with 182 drugs. Click any drug to see the details.

1 of the 2 ingredients in Chewable Probiotic Natural Grape Flavor interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus DDS-1

Each ingredient & the kinds of drugs it affects

For each ingredient in Chewable Probiotic Natural Grape Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus DDS-11 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus DDS-1 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chewable Probiotic Natural Grape Flavor, from the product label.

American Health

See all American Health products
Name
American Health, Inc.
City
Ronkonkoma
State
NY
ZipCode
11779
Phone Number
800-445-7137
Web Address
www.AmericanHealthUS.com
Pharmacist Counseling Corner

Chewable Probiotic Natural Grape Flavor by American Health: Common Questions

Does Chewable Probiotic Natural Grape Flavor by American Health interact with any medications?
Yes. Based on its ingredients, Chewable Probiotic Natural Grape Flavor has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chewable Probiotic Natural Grape Flavor contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this probiotic while I'm on antibiotics?
You can, but timing is important. Antibiotics can kill the live organisms in this probiotic, making it less effective. Talk with your doctor or pharmacist about spacing out when you take them — many people take the probiotic a few hours before or after their antibiotic dose.
Will this help with my IBS?
Lactobacillus acidophilus is rated possibly effective for IBS, meaning some evidence supports it but more research is needed. Results vary from person to person, so give it time and check in with your doctor about whether you're noticing a difference.
Is it safe to take while breastfeeding?
We don't have safety data on file for Bifidobacterium animalis lactis in breastfeeding, and lactation safety information for Lactobacillus acidophilus isn't listed in our data. Talk with your doctor or pharmacist before starting to make sure it's right for you.
What are the side effects?
Most people tolerate it well, but some experience mild stomach discomfort, bloating, gas, diarrhea, or nausea — these are uncommon. Rarely, rashes or itching have been reported, though it's not always clear what caused them.
Why does it matter that this has live organisms?
Because they're alive, antibiotics can kill them before they do their job. Also, in very rare cases, these organisms have caused serious infections in people with weakened immune systems — another reason to check with your doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Chewable Probiotic Natural Grape Flavor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chewable Probiotic Natural Grape Flavor label
Go deeper

The Full Monographs Behind Chewable Probiotic Natural Grape Flavor’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph →
Sources

Sources & How We Checked

Chewable Probiotic Natural Grape Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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